Cluster	SYMBOL	GENE ID	GENE NAME	OTHER NAME	SYNONYMS	ORGANISM	NUCLEOTIDE	PROTEIN	GENOMIC	Uniprot	Location	Complex	Function group	Interaction	Function	Unigene	Related Papers	Disorder	Sequence
1	PRKAA1	5562	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	AMPK|AMPKa1	human	NM_006251.5,NM_206907.3,XM_006714482.1	NP_006242.5,NP_996790.3,XP_006714545.1	NC_000005.10,NC_018916.2,NT_006576.17,NW_004929321.1	Q13131	Cytoplasm. Nucleus.	NULL			Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2. In response to nutrient limitation, promotes autophagy by phosphorylating and activating ATG1/ULK1. AMPK also acts as a regulator of circadian rhythm by mediating phosphorylation of CRY1, leading to destabilize it. May regulate the Wnt signaling pathway by phosphorylating CTNNB1, leading to stabilize it. Also has tau-protein kinase activity: in response to amyloid beta A4 protein (APP) exposure, activated by CAMKK2, leading to phosphorylation of MAPT/TAU; however the relevance of such data remains unclear in vivo. Also phosphorylates CFTR, EEF2K, KLC1, NOS3 and SLC12A1. {ECO:0000269|PubMed:11518699, ECO:0000269|PubMed:11554766, ECO:0000269|PubMed:12519745, ECO:0000269|PubMed:14651849, ECO:0000269|PubMed:15866171, ECO:0000269|PubMed:17486097, ECO:0000269|PubMed:17711846, ECO:0000269|PubMed:18184930, ECO:0000269|PubMed:18439900, ECO:0000269|PubMed:20074060, ECO:0000269|PubMed:20160076, ECO:0000269|PubMed:21205641}.	Hs.43322	1322130,2900138,7907095,8094892,8163463,8557660,8621713,8626596,8663446,8910387,9091312,9224708,9710607,9845345,9857077,10698692,10760274,10862786,11042152,11052978,11165240,11171059,11500364,11546797,11903059,11913976,11971957,11997383,12091379,12194824,12368907,12391032,12477932,12788940,12791703,12847291,12853467,12869384,12890675,14557259,14651849,14702039,14709557,14970221,14976552,14985344,14985505,15024086,15261145,15485651,15489334,15866171,16054041,16054095,16306228,16344560,16405649,16466905,16806233,16912160,17028174,17088252,17584647,18195011,18276112,18303014,18347656,18359290,18403135,18439900,18480843,18614941,18663353,18674809,18801964,18836454,18950855,18976975,18996102,19020741,19049348,19050283,19138981,19197243,19211918,19322201,19442239,19491292,19502591,19556893,19616115,19720090,19723093,19723094,19723101,19723105,19728147,19887561,19913121,19914239,19923924,19948975,19966861,20080969,20103647,20167678,20170185,20217115,20368287,20368732,20392842,20421294,20462511,20538596,20562859,20564492,20602615,20622004,20628086,20660302,20682687,20801214,20821366,20861072,20876741,21048031,21072212,21079763,21088205,21209024,21232561,21344388,21416543,21432774,21474997,21516116,21567395,21651489,21670147,21678424,21728993,21768291,21775054,21807092,21892142,21909354,21988832,21994947,22007913,22012985,22021095,22037551,22065577,22212710,22363791,22378745,22406815,22419736,22434430,22462548,22480519,22553202,22564965,22607554,22674476,22688514,22815988,22833096,22869372,22897928,22935535,22939624,22939629,22988252,23000302,23022380,23171948,23221389,23228943,23291726,23306156,23324179,23367447,23376776,23417417,23418352,23453806,23455922,23463002,23475945,23506848,23589839,23592276,23602568,23625915,23648710,23671028,23677989,23685869,23712032,23716691,23723070,23728343,23778007,23800577,23819460,23861218,23878245,23883584,23899558,23904275,23963659,23982477,24018441,24047437,24055274,24072697,24080159,24095280,24104889,24186207,24190973,24371122,24395629,24414799,24419061,24441100,24472739,24491542,24561578,24619908,24655923,24700636,24711643,24722188,24770722,24797263,24799027,24871657,24916949,24925061,24955726,24988326,25017332,25024613,25025067,25047736,25122135,25151490,25225183,25256353,25330949,25348630,25356873,25362209,25367309,25404641,25412657,25416956,25425646,25484082,25556665,25586669,25595658,25632961,25651975,25656579,25659498,25679763,25686248,25687571,25703587,25727016,25840010,25846811,25852190,25858560,25874865,25902870,25921289,25933205,25937278,25955819,25963833,25980607,26029847,26041108,26121488,26124005,26143491,26186194,26196392,26198640,26232429,26236947,26276392,26322680,26330165,26344197,26427441,26439621,26479318,26496610,26638075,26876938	15		NP_006242.5|MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ,NP_996790.3|MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ,XP_006714545.1|MLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
1	PRKAA2	5563	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	human	NM_006252.3	NP_006243.2	NC_000001.11,NC_018912.2,NT_032977.10,NW_004929290.1	P54646	Cytoplasm.  Nucleus.	NULL			Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. Involved in insulin receptor/INSR internalization (PubMed:25687571). AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2. In response to nutrient limitation, promotes autophagy by phosphorylating and activating ATG1/ULK1. AMPK also acts as a regulator of circadian rhythm by mediating phosphorylation of CRY1, leading to destabilize it. May regulate the Wnt signaling pathway by phosphorylating CTNNB1, leading to stabilize it. Also phosphorylates CFTR, EEF2K, KLC1, NOS3 and SLC12A1. Plays an important role in the differential regulation of pro-autophagy (composed of PIK3C3, BECN1, PIK3R4 and UVRAG or ATG14) and non-autophagy (composed of PIK3C3, BECN1 and PIK3R4) complexes, in response to glucose starvation. Can inhibit the non-autophagy complex by phosphorylating PIK3C3 and can activate the pro-autophagy complex by phosphorylating BECN1 (By similarity). {ECO:0000250|UniProtKB:Q8BRK8, ECO:0000269|PubMed:11518699, ECO:0000269|PubMed:11554766, ECO:0000269|PubMed:12519745, ECO:0000269|PubMed:14651849, ECO:0000269|PubMed:15866171, ECO:0000269|PubMed:17486097, ECO:0000269|PubMed:17711846, ECO:0000269|PubMed:18184930, ECO:0000269|PubMed:20074060, ECO:0000269|PubMed:20160076, ECO:0000269|PubMed:21205641, ECO:0000269|PubMed:25687571, ECO:0000269|PubMed:7959015}.	Hs.437039	1322130,1365882,1536860,2900138,7959015,7988703,8889548,9148944,9224708,10642499,10698692,10760274,11052978,11171059,11257506,11389854,11500364,11797013,12067722,12091379,12391032,12413941,12427743,12444247,12456889,12477932,12511592,12519745,12663462,12740371,12788940,12847291,12853467,12941758,14532170,14613924,14651849,14709557,14729328,14742438,14985344,14985505,15024086,15058305,15060529,15231718,15297373,15371448,15489334,15572372,15640157,16054041,16054095,16054096,16275868,16344560,16483872,16505254,16518831,16567511,16598851,16624523,16670154,16710414,16801347,16984726,17012231,17179156,17950019,18029386,18195011,18439900,18614941,18674809,18801964,18836454,18974883,18996102,19170765,19434633,19440859,19470831,19502591,19528236,19574280,19616115,19720090,19720831,19723084,19728147,19836452,19913121,19948975,20124121,20167927,20217115,20392842,20558612,20562859,20602615,20628086,20647423,20682687,20801214,20821366,20876741,21209024,21344388,21432774,21516116,21543851,21651489,21673972,21825219,22137581,22212710,22286170,22305490,22561688,22728651,22797923,22897928,22939624,23000302,23293026,23396962,23476055,23723070,24414799,24722188,25126726,25184681,25241761,25416956,25590814,25687571,25799226,25840010,25846811,25858560,26108355,26186194,26344197,26351140,26427488,26496610,26876938	15		NP_006243.2|MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFFEMCASLITTLAR
1	ULK1	8408	Serine/threonine-protein kinase ULK1	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	human	NM_003565.2,XM_011538798.1,XM_011538799.1,XR_944753.1	NP_003556.1,XP_011537100.1,XP_011537101.1	NC_000012.12,NC_018923.2,NT_029419.13,NW_004929386.1	O75385	Cytoplasm, cytosol. Preautophagosomal structure.	NULL			Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. {ECO:0000269|PubMed:18936157, ECO:0000269|PubMed:21460634, ECO:0000269|PubMed:21795849}.	Hs.47061	8889548,9693035,9872452,11076863,11146101,12477932,14702039,15014045,16616143,16940348,17081983,17192257,17353931,17595159,18007665,18936157,19211835,19225151,19258318,19287211,19597335,19690328,20562859,20921139,21072212,21169990,21205641,21241894,21258367,21460630,21460634,21475306,21518141,21560199,21795849,21819378,22321011,22354037,22456507,22539723,22585231,22613832,22885598,23027865,23043107,23078367,23262492,23291726,23392225,23524951,23716696,23849170,23863160,24013547,24066173,24119841,24306881,24603492,24671035,24955726,25040165,25126726,25127057,25266655,25429619,25541949,25678702,25686248,25701603,25714809,25723488,25749095,25761126,25792739,25847297,25891078,25892232,25925668,25980607,26018823,26282792,26310906,26347139	15		NP_003556.1|MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPIAANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA,XP_011537100.1|MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAVHRSGRAAEASPPNICLVFRSSAIRRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA,XP_011537101.1|MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA
1	ULK2	9706	Serine/threonine-protein kinase ULK2	ULK2	ATG1B|Unc51.2	human	NM_001142610.1,NM_014683.3,XM_011524087.1,XR_934124.1,XR_934125.1	NP_001136082.1,NP_055498.3,XP_011522389.1	NC_000017.11,NC_018928.2,NT_010718.17,NW_004929405.1	Q8IYT8	Cytoplasmic vesicle membrane.	NULL			Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons. {ECO:0000269|PubMed:18936157, ECO:0000269|PubMed:21460634, ECO:0000269|PubMed:21460635, ECO:0000269|PubMed:21690395, ECO:0000269|PubMed:21795849}.	Hs.168762	9734811,10557072,12471243,12477932,14702039,14702098,15014045,15489334,16169070,16344560,18029348,18936157,19225151,20379614,20562859,21282530,21475306,21988832,23043107,24923441,25925668,26052940	15		NP_001136082.1|MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTSTASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQSKAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASSKAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKCSIERRLSALCHSTATV,NP_055498.3|MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTSTASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQSKAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASSKAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKCSIERRLSALCHSTATV,XP_011522389.1|MRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTSTASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQSKAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASSKAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKCSIERRLSALCHSTATV
1	Ulk1	22241		Ulk1	AU041434|Unc51.1|mKIAA0722	mouse	NM_009469.3,XM_006534851.2,XM_006534852.1,XM_011249419.1,XM_011249420.1	NP_033495.2,XP_006534914.1,XP_006534915.1,XP_011247721.1,XP_011247722.1	AC_000027.1,NC_000071.6,NT_109320.5,NW_001030796.1	A0A0R4J0B3,O70405,Q6PB82	NULL	NULL				Mm.271898	8889548,9600096,10349636,10624947,10725249,10922068,11042159,11076861,11217851,11423996,12466851,12477932,12520002,12693553,12904583,14610273,15014045,15226823,15489334,15782199,16141072,16141073,16602821,17389358,17595159,17855365,17967808,18443221,18539900,18799693,18936157,18981720,19211835,19258318,19597335,19807128,20498061,21205641,21220506,21258367,21267068,21368103,21383122,21460634,21460635,21677750,21690395,21795849,21855797,21969579,22275429,22452982,22493260,22539723,22613832,22932492,23027865,23219390,23291478,23448468,23525089,23685627,23870125,24135897,24275123,24317201,24671035,24895007,25040165,25541949,25680463,25980607,26310906,26365490,26371245	19		NP_033495.2|MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA,XP_006534914.1|MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQATLFLPVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA,XP_006534915.1|MVPGWCWLAVSTSSQELILPLSSDLLLYRNGESLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQATLFLPVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA,XP_011247721.1|MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREVGEAPAEASQSRTPSPRDTLPPKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQATLFLPVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA,XP_011247722.1|MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREVGEAPAEASQSRTPSPRDTLPPKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA
1	Ulk2	29869		Ulk2	A830085I22Rik|AU015340|Unc51.2|mKIAA0623	mouse	NM_013881.4,XM_006533508.2,XM_006533509.2	NP_038909.3,XP_006533571.1,XP_006533572.1	AC_000033.1,NC_000077.6,NT_096135.6,NW_001030475.1,NW_001032132.1,NW_001032572.1	Q3UG39,Q9QY01	Cytoplasmic vesicle membrane.	NULL				Mm.162025	8889548,9600096,10349636,10557072,10624947,10725249,10922068,11042159,11076861,11217851,11544199,12466851,12477932,12693553,14610273,14681479,15489334,15782199,16141072,16141073,16602821,16887332,17273973,17389358,18443221,18799693,18936157,19597335,21267068,21460635,21690395,22493260,23291478,24135897,24275123,24923441,26371245	19		NP_038909.3|MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPVKKSCPVPVPVYSGPVPGSSCSSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTTARRASNEFFMCGGQCQPTVSPHSETAPIPVPTQVRNYQRIEQNLISTASSGTNPHGSPRSAVVRRSNTSPMGFLRVGSCSPVPGDTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSGSPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHAGAGYSYSPQPSRPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQSKAVFGRSVSTGKLSEQQVKAPLGGHQGSTDSLNTERPMDVAPAGACGVMLALPAGTAASARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGSSPPGAEGAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQVKSGKLSPSMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKYKCSIERRLSALCCSTATV,XP_006533571.1|MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPVKKSCPVPVPVYSGPVPGSSCSSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTTARRASNEFFMCGGQCQPTVSPHSETAPIPVPTQVRNYQRIEQNLISTASSGTNPHGSPRSAVVRRSNTSPMGFLRVGSCSPVPGDTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSGSPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHAGAGYSYSPQPSRPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQSKAVFGRSVSTGKLSEQQVKAPLGGHQGSTDSLNTERPMDVAPAGACGVMLALPAGTAASARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGSSPPGAEGAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQVKSGKLSPSMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKSLSSWSYLNCCWKEERKCIHCVHLGAKIEQEPW,XP_006533572.1|MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPVKKSCPVPVPVYSGPVPGSSCSSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTTARRASNEFFMCGGSAVVRRSNTSPMGFLRVGSCSPVPGDTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSGSPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHAGAGYSYSPQPSRPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQSKAVFGRSVSTGKLSEQQVKAPLGGHQGSTDSLNTERPMDVAPAGACGVMLALPAGTAASARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGSSPPGAEGAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQVKSGKLSPSMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKSLSSWSYLNCCWKEERKCIHCVHLGAKIEQEPW
1	ATG1	852695	Serine/threonine-protein kinase ATG1 {ECO:0000305}		APG1|AUT3|CVT10	baker's yeast	NM_001181045.1	NP_011335.1	NC_001139.9	P53104	Cytoplasm.  Preautophagosomal structuremembrane.	NULL			Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER- associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. Finally, ATG1 is also required for the maintenance of cell viability under starvation and for glycogen storage during stationary phase. Plays a role in genome stability through suppression of abnormal mitosis under starvation, and in regulation of filamentous growth. {ECO:0000269|PubMed:10995454, ECO:0000269|PubMed:11486014, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:11904149, ECO:0000269|PubMed:12589048, ECO:0000269|PubMed:14723849, ECO:0000269|PubMed:17295840, ECO:0000269|PubMed:17699586, ECO:0000269|PubMed:17700056, ECO:0000269|PubMed:18077553, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:18818209, ECO:0000269|PubMed:20439775, ECO:0000269|PubMed:20855505, ECO:0000269|PubMed:21228276, ECO:0000269|PubMed:21460632, ECO:0000269|PubMed:21490424, ECO:0000269|PubMed:21576396, ECO:0000269|PubMed:21712380, ECO:0000269|PubMed:22722939, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:22785534, ECO:0000269|PubMed:22885598, ECO:0000269|PubMed:22977244, ECO:0000269|PubMed:23230142, ECO:0000269|PubMed:23382696, ECO:0000269|PubMed:23549786, ECO:0000269|PubMed:24905091, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:8663607, ECO:0000269|PubMed:9190802, ECO:0000269|PubMed:9224897}.		8849441,9169869,9190802,9224892,9224897,10688190,10995454,11309418,11486014,11689437,12589048,15659643,15743910,15901835,16319894,16554755,17166847,18077553,18287526,18287533,18497569,18552550,18701704,18829864,19223769,19269370,19337029,19369420,19398890,19591838,19793921,19805182,19840948,19995911,20065092,20093466,20439775,20444982,20489023,20953146,21127252,21228276,21368826,21460632,21576396,21712380,21784249,22199229,22240591,22282571,22447937,22643220,22768199,22778255,22782902,22826123,22875988,22885598,23043107,23078654,23322149,23332755,23382696,23549786,23716696,23755917,23858448,23904270,24239358,24440502,24586198,24793651,24968893,25139988,25519895,25921291,25998554,26061644,26166702,26181331,26673895	28	1->29,319->666,764->790,825->897	NP_011335.1|MGDIKNKDHTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVNEDLSSYELEDDLPELESKSKGIVESNMFVSEYLSKQPKSPNSNLAGHQSMADNPAELSDALKNSNILTAPAVKTDHTQAVDKKASNNKYHNSLVSDRSFEREYVVVEKKSVEVNSLADEVAQAGFNPNPIKHPTSTQNQNVLLNEQFSPNNQQYFQNQGENPRLLRATSSSSGGSDGSRRPSLVDRRLSISSLNPSNALSRALGIASTRLFGGANQQQQQQQITSSPPYSQTLLNSQLFHELTENIILRIDHLQHPETLKLDNTNIVSILESLAAKAFVVYSYAEVKFSQIVPLSTTLKGMANFENRRSMDSNAIAEEQDSDDAEEEDETLKKYKEDCLSTKTFGKGRTLSATSQLSATFNKLPRSEMILLCNEAIVLYMKALSILSKSMQVTSNWWYESQEKSCSLRVNVLVQWLREKFNECLEKADFLRLKINDLRFKHASEVAENQTLEEKGSSEEPVYLEKLLYDRALEISKMAAHMELKGENLYNCELAYATSLWMLETSLDDDDFTNAYGDYPFKTNIHLKSNDVEDKEKYHSVLDENDRIIIRKYIDSIANRLKILRQKMNHQN
1	AOR_1_1230144	5993230			"AO090023000715"		XM_001821176.2	XP_001821228.1	NW_001884666.1	Q2UGT9	NULL	NULL					16372010	44	1->9,50->98,185->235,298->332,383->457	XP_001821228.1|MSTTLPKNGDSRLLSLPIRASAYHQDPLIYIDREAKHIQHSLQALIDAQSEGLLAGLQGPRLNETPTGSSTPSTEPSVLQRPLTIPVRQPVAEKISLRAAREGIFKSIFDLLKLREEEREILTARVAVRTDALDEINGFITKKAGLEEAVSTIYKNRESQLTKELREEGHKLETDIHELETKLSQMRARHRHVMEELAHMENSVESKLSSYKASLSLLESDIQKFLQKPPIPPQSSFANGTTLYSLNPKRRTLDMALEQWTTEQSELRKRQEEVDHEIQALEAGGGVWKQVVLEVCRFERRLKVEMRRSLQNQSQVLESSRAAENNSELDHVRGILEDLHKTTEHVEHYLGIAEDKDWKLLVCCIAAELEALREARAMLLDAFDIPDEGPSQSSERRVPDKSGENNLHNTHQDPLGVDNPDPPADLLQDAEEHHSDTISRSEDEDDEPDPAWLLPET
1	VOLCADRAFT_58372	9624735				volvox	XM_002948517.1	XP_002948563.1	NW_003307553.1	D8TPY1	NULL	NULL					20616280	81		XP_002948563.1|MAHSQAPRRTIGNWEILEVVGSGSFAIVWKARHLTTGTFAAVKEILSDRLNKKLHESLESEIAALQRLRHSNIVGLLDLYKEPGKIFLVLEYCAGGDLAQHLRRRGPLSEASCRYLLRQLAEGLKVLRQHNVIHRDLKPQNLLLSDNGSSPALKIADFGFARSLQPAGLAETLCGSPLYMAPEVLQLHRYDAKADLWSVGTILFELLTGKPPFNGANHLQLIQNIERGDAVLPDHVSRSLSPSCRQLLHQLLRRNP
1	VOLCADRAFT_67317	9627678				volvox	XM_002956676.1	XP_002956722.1	NW_003307607.1	D8UDK2	NULL	NULL					20616280	81		XP_002956722.1|MLDNYHVIELIGEGSFGKVYKGRRKCTGQITAMKFILKQGKSEKDIKNLRQEIEILRQLRHENIIQMLDAFETKTEFCVVTEYAQGELFEILEDDQNLPEEVVRGIAKQLVRALHYLHSNRIIHRDMKPQNILIGSNGVVKLCDFGFARAMSCNTMVLTSIKGTPLYMAPELVQEQPYNHTVDLWSLGVILFELHVGQPPFYTNSIYSLIHHIVKDPVRFPTNITPEFKSFLKGLLNKKPQDRLGWPQLLEHPFVRETDTERLVREKMLADAMEVAEGSRAWKVRWTE
2	ATG2A	23130	Autophagy-related protein 2 homolog A	ATG2A		human	NM_015104.2,XM_005273849.2,XM_005273850.2,XM_011544863.1,XM_011544864.1,XM_011544865.1,XM_011544866.1,XM_011544867.1,XM_011544868.1,XR_949846.1,XR_949	NP_055919.2,XP_005273906.1,XP_005273907.1,XP_011543165.1,XP_011543166.1,XP_011543167.1,XP_011543168.1,XP_011543169.1,XP_011543170.1	NC_000011.10,NC_018922.2,NT_167190.2,NW_004929380.1	Q2TAZ0	Preautophagosomal structure membrane.	NULL			Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000269|PubMed:22219374}.	Hs.370671	9253601,9455477,12477932,19615732,20379614,20562859,21887408,22219374,26496610,26673895	15		NP_055919.2|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD,XP_005273906.1|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD,XP_005273907.1|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD,XP_011543165.1|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD,XP_011543166.1|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLGMRDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD,XP_011543167.1|MESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD,XP_011543168.1|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLCHS,XP_011543169.1|MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGQELASQVPGAPLPAALAPTGPRTHGARRGAAGGSTMSSWRSS,XP_011543170.1|MVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD
2	ATG2B	55102	Autophagy-related protein 2 homolog B	ATG2B	C14orf103	human	NM_018036.5,XM_006720187.1,XM_011536888.1,XM_011536889.1,XR_943482.1,XR_943483.1	NP_060506.5,XP_006720250.1,XP_011535190.1,XP_011535191.1	NC_000014.9,NC_018925.2,NT_026437.13,NW_004929393.1	Q96BY7	Preautophagosomal structure membrane.	NULL			Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000269|PubMed:22219374}.	Hs.168241	12477932,12508121,14702039,15028280,15489334,19197948,20562859,22219374,22350415,23752268,25281560,25322940,25921289,26186194,26280900,26496610,26638075	15		NP_060506.5|MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGTALEIRIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQNEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHISLHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEILYLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGTVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGTLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD,XP_006720250.1|MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGTALEIRIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQNEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEVFFSMADMDMSHSLSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHISLHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEILYLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGIVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGTLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD,XP_011535190.1|MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGTALEIRIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQNEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHISLHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEILYLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGIVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFRRSGLW,XP_011535191.1|MRQKQLVHLLAVLQPTWGEFLDHHKEQPVRGSTFPSNLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHISLHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEILYLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGIVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGTLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD
2	Atg2a	329015	Autophagy-related protein 2 homolog A	Atg2a	1810013C15Rik|A830054M12|BC023754|mKIAA0404	mouse	NM_194348.3,XM_006531772.2,XM_006531773.2,XM_006531774.2,XM_006531775.2,XR_388259.1	NP_919329.2,XP_006531835.1,XP_006531836.1,XP_006531837.1,XP_006531838.1	AC_000041.1,NC_000085.6,NT_082868.6,NW_001030639.1	Q6P4T0	Preautophagosomal structure membrane.	NULL			Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion (By similarity). Mediates the intracellular lifestyle of Cryptococcus neoformans by supporting infection. {ECO:0000250, ECO:0000269|PubMed:21698225}.	Mm.277384	10349636,10922068,11042159,11076861,11217851,12466851,12477932,14610273,14621295,15782199,16141072,16141073,18799693,22710871,26496610,26764384	19		NP_919329.2|MSRWLWPWSNCVKERVCRYLLQHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLETWSVNEFLRSMESPLELVEGFVSSIEVAVPWAALLTDHCTVCVSGLQLTLQPRQGSGPGAADSQSWASCMTTSLQLAQECLREGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLNTVVRVEHSLGDEDRSVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLSGVCLYFEELPSQADPPQPPLQIGSCTGYVELMVRLKQNEAFPGPKLEVSGQLGSLHLLLTPRQLQQLQRLLSAVNLADPAGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAESLSLYPITNPLNLDSTDLFFSMAGLTSSVTSAVSELSVYSVDLGSSVHSNMAFHRPSTPPHSGGKMAPTPLLDTTRPDSLVKMTLGGVSLTLLQTASPSSGPSDLPTHFFAEFDAAKDGPFGSRDFSHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSHSRRTSSTEVHFGQLEVLECLWPRAATEPEYTEILSFPSHSGSEASARPCAHLRHTQTIRRVLKSRSRRSTACHCHSELSLDLADFQSDVELGSLDRLAALFRQVTTPSEPPAGLLTEPPQATELQTVFRLSAPRATLRLRFPIPDLRPDRDPWAGQAVRAEQLRLELSEPQFRSELNSGPGPPAPTRLELTCSDLQGIYEDGEKPPVPCLRVSKALNPRSTEAKYFLPQVVVTLNPQSSGTQWETAYEKGRDLELSTESPCELQQPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCTLDVIMPSAHIFLPSKEVYESIYNRINNDLLMWEPADLLPTSSAAARPPGSSGFKMCKSAFKLDSDSDEEDAQFFSMASGVPQTPAPEPSRRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDVTHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKAKLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEEGVTERGTLGRKGQGPPMLSAAVRIHLDPHKNVKEFLVTVRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITVLHTHLFSCAVDYRPLYLPVRVLVTAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVESLDLRRDYVCVLDIDLLELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYLTSSGDLHPPPRPPSPTEIAGQKLSESPASLPSCLPVETALINQRDLTDALLDTERRGLQELAQSSGGPLPQASPVSVYLFPGERSGAQAPLPPPGASSHTLGSKAKEHENEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIIVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHPTYRARVGLTGPRVSPSRSSGPNRPQNSWRTQGGIGRQHQVLMEIQLSKVSFQHEVYPEESAIAGGLGQELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTSSVGGPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDTSEAPRETHSRPGSPQEGQSEDTETASNPPEAPGSSHSSSDQQPIYFREFRFTSEVPICLDYHGKHVTVDQVGTFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLCYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASPVSRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEEAQD,XP_006531835.1|MSRWLWPWSNCVKERVCRYLLQHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLETWSVNEFLRSMESPLELVEGFVSSIEVAVPWAALLTDHCTVCVSGLQLTLQPRQGSGPGAADSQSWASCMTTSLQLAQECLREGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLNTVVRVEHSLGDEDRSVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLSGVCLYFEELPSQADPPQPPLQIGSCTGYVELMVRLKQNEAFPGPKLEVSGQLGSLHLLLTPRQLQQLQRLLSAVNLADPAGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAESLSLYPITNPLNLDSTDLFFSMAGLTSSVTSAVSELSVYSVDLGSSVHSNMAFHRPSTPPHSGGKMAPTPLLDTTRPDSLVKMTLGGVSLTLLQTASPSSGPSDLPTHFFAEFDAAKDGPFGSRDFSHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSHSRRTSSTEVHFGQLEVLECLWPRAATEPEYTEILSFPSHSGSEASARPCAHLRHTQTIRRVLKSRSRRSTACHCHSELSLDLADFQSDVELGSLDRLAALFRQVTTPSEPPAGLLTEPPQATELQTVFRLSAPRATLRLRFPIPDLRPDRDPWAGQAVRAEQLRLELSEPQFRSELNSGPGPPAPTRLELTCSDLQGIYEDGEKPPVPCLRVSKALNPRSTEAKYFLPQVVVTLNPQSSGTQWETAYEKGRDLELSTESPCELQQPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCTLDVIMPSAHIFLPSKEVYESIYNRINNDLLMWEPADLLPTSSAAARPPGSSGFKMCKSAFKLDSDSDEEDAQFFSMASGVPQTPAPEPSRRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDVTHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKAKLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEEGVTERGTLGRKGQGPPMLSAAVRIHLDPHKNVKEFLVTVRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITVLHTHLFSCAVDYRPLYLPVRVLVTAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVESLDLRRDYVCVLDIDLLELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYLTSSGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCLPVETALINQRDLTDALLDTERRGLQELAQSSGGPLPQASPVSVYLFPGERSGAQAPLPPPGASSHTLGSKAKEHENEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIIVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHPTYRARVGLTGPRVSPSRSSGPNRPQNSWRTQGGIGRQHQVLMEIQLSKVSFQHEVYPEESAIAGGLGQELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTSSVGGPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDTSEAPRETHSRPGSPQEGQSEDTETASNPPEAPGSSHSSSDQQPIYFREFRFTSEVPICLDYHGKHVTVDQVGTFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLCYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASPVSRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEEAQD,XP_006531836.1|MVTLNPQSSGTQWETAYEKGRDLELSTESPCELQQPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCTLDVIMPSAHIFLPSKEVYESIYNRINNDLLMWEPADLLPTSSAAARPPGSSGFKMCKSAFKLDSDSDEEDAQFFSMASGVPQTPAPEPSRRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDVTHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKAKLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEEGVTERGTLGRKGQGPPMLSAAVRIHLDPHKNVKEFLVTVRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITVLHTHLFSCAVDYRPLYLPVRVLVTAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVESLDLRRDYVCVLDIDLLELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYLTSSGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCLPVETALINQRDLTDALLDTERRGLQELAQSSGGPLPQASPVSVYLFPGERSGAQAPLPPPGASSHTLGSKAKEHENEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIIVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHPTYRARVGLTGPRVSPSRSSGPNRPQNSWRTQGGIGRQHQVLMEIQLSKVSFQHEVYPEESAIAGGLGQELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTSSVGGPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDTSEAPRETHSRPGSPQEGQSEDTETASNPPEAPGSSHSSSDQQPIYFREFRFTSEVPICLDYHGKHVTVDQVGTFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLCYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASPVSRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEEAQD,XP_006531837.1|MWEPADLLPTSSAAARPPGSSGFKMCKSAFKLDSDSDEEDAQFFSMASGVPQTPAPEPSRRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDVTHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKAKLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEEGVTERGTLGRKGQGPPMLSAAVRIHLDPHKNVKEFLVTVRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITVLHTHLFSCAVDYRPLYLPVRVLVTAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVESLDLRRDYVCVLDIDLLELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYLTSSGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCLPVETALINQRDLTDALLDTERRGLQELAQSSGGPLPQASPVSVYLFPGERSGAQAPLPPPGASSHTLGSKAKEHENEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIIVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHPTYRARVGLTGPRVSPSRSSGPNRPQNSWRTQGGIGRQHQVLMEIQLSKVSFQHEVYPEESAIAGGLGQELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTSSVGGPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDTSEAPRETHSRPGSPQEGQSEDTETASNPPEAPGSSHSSSDQQPIYFREFRFTSEVPICLDYHGKHVTVDQVGTFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLCYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASPVSRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEEAQD,XP_006531838.1|MASGVPQTPAPEPSRRQSQSTFSTLVTVLKGRITALCEAKDETGKRLDVTHGELVLDVEQGTIFSVAQYRGQPGLGYFCLEAEKAKLYHRAAIEDYLLPTHLEVPSFAPPAQLAPTIYPSEEGVTERGTLGRKGQGPPMLSAAVRIHLDPHKNVKEFLVTVRLHKATLRHYMAPPEQSWHSQLLDFLDVLDDPVLGYLPPTVITVLHTHLFSCAVDYRPLYLPVRVLVTAETFTLSSNIVMDTSTFLLRFILDDSALYLSDKCEVESLDLRRDYVCVLDIDLLELVIKTWKGSTEGRLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYLTSSGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCLPVETALINQRDLTDALLDTERRGLQELAQSSGGPLPQASPVSVYLFPGERSGAQAPLPPPGASSHTLGSKAKEHENEEEGDGDTLDSDEFCILDAPGLGIAPRDGEPIVTQLHPGPIIVHDGHFSQPLGSTDLLRAPAHFPVPSSRVVLREVSFIWHLYGGRDFGLHPTYRARVGLTGPRVSPSRSSGPNRPQNSWRTQGGIGRQHQVLMEIQLSKVSFQHEVYPEESAIAGGLGQELDERPLSRQVLIVQELEIRDRLATSKINKFLHLHTSERLPRRTHSNMLTIKALHVAPTSSVGGPECCLRVSMMPLRLNVDQDALFFLKDFFTSLAASINPMVPGDTSEAPRETHSRPGSPQEGQSEDTETASNPPEAPGSSHSSSDQQPIYFREFRFTSEVPICLDYHGKHVTVDQVGTFMGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLCYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLIRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPASPVSRSLQDKRSSRKLRRGQQPADLREGMAKAYDAVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPIIVATEATSNVLGGMRNQILPDAHKDHALKWRLEEAQD
2	Atg2b	76559	Autophagy-related protein 2 homolog B	Atg2b	2410024A21Rik|AI047755|AI503411|AW558123|C030004M05Rik|C630028L02Rik|mKIAA4067	mouse	NM_029654.4,XM_006516360.1,XM_006516361.1	NP_083930.5,XP_006516423.1,XP_006516424.1	AC_000034.1,NC_000078.6,NT_039551.8,NW_001030504.1	Q80XK6	Preautophagosomal structure membrane.	NULL			Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000250}.	Mm.114362,Mm.125279	1698780,8889548,10349636,10922068,11042159,11076861,11217851,12466851,12477932,12520002,15489334,16141072,16141073,16602821,21267068,22710871	19		NP_083930.5|MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRVATGSEPMYWSSFMTSSMQLAKECLSQKLTDEQGEASQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGAALEIRVDRTVYCDETADESSGVNVHQPTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIVYEPHPQLTRTLPEIAPSDPVQIGRLLGRLELSLTLKQNEVLPGAKLDVDGQIDSFHLFLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSMGVSSEKSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPHMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFADHKEQPVRGPAFQSDVVHPASLQKAALSSRSASVDESRPEFICRLALGIFSVSVLHIDPLSPAETSLNVNPLTRMATDFFSCVEKMDPAIFSTGDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRHFSTDMSVGQMEFLECLFPTDCHSVPSHYTELLTFHSKEGTDAHLPVCLQLHYKHSETRGPQGNQARLSSVPQKAELQIKLNPVCCELDISIVDRLNSLLQPQKLTTVEMMASHMYASYNKHISLHKAFTEVFLDDSHSPANRRVSVQVATPALHLSVRFPIPDLRSDQERGPWFKKSLQKETLHLEFTDLESKTEFVGGSTPEQTKLELTFRELSGSFQEEKGGPSVKFFHVSGGVDGDTASSDDFDWPRMVLKINPPAMHSILERIAAEEEEENDGHYQEEEDGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELLLPNIHLTLPNKGFYEKLYNRIFNDLLLWEPTAPSPVETLENVSYGIGLSVASQLINTFSKDSFSPFKSAVHYDEDSGSEEETLQYFSAVDPNYRSRRKKKLDSQNKNSQSFLSVLLSINHGLMAVFTDVKQENGDPMESKHGEFWLEFNSGSFFCVTKYEGFEDKHYICLHSSSLRLYHKGIVDGAILPTETRLPCSTRPHWLEPTIYSSEEDGLSRTASDGVGGDNLNMLSVAVKILSDKSESNTKEFLVAVGLKGATLQHRVLPAGLSWHEQILNFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLHLPLRSLLTVETFSISSSVALDKSSSTLRIIMDEAALHLSDKCNTVTVNLNRDYVRVMDMGLLELTITAVKSDSDGEQTAPRFELHCSSDVVHIRTCSDSCAALMNLIQYVASYGDLHGPHKAEMKPGVPQRKPKVDSSARSSSHGPVLPEADQQILRDLMSDAMEEIDLQQASAPVGPQANGVLDEKSHTQEPCCSDLFLFPDESGNVSQESSPAYPSLTHHLISDAVTGVTAENDDFCILFAPKTVVQEKEEEPVIKIMVDDAIVIKDDYFSLPITRTDSSKAPLHFPIPAVRYVVKEVSLVWHLYGGKDFATAPPTSPAKSYIPHSSPSQTPTRHGRHTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPECESSLLEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKDMPRKAHSNMLTIKALHVRPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSTEVELLLTPDPEVTKSPGADVTCSLPRHLSTSKEPNLVVSFPGPKQASPNHRANSAEGGNGLEEDVSAEETSFSDQPVFFREFRFTAEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLFYRHGLLGIDKLFSYAISEWLSDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPSTLSIEPKKAKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVRPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGED,XP_006516423.1|MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRVATGSEPMYWSSFMTSSMQLAKECLSQKLTDEQGEASQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGAALEIRVDRTVYCDETADESSGVNVHQPTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIVYEPHPQLTRTLPEIAPSDPVQIGRLLGRLELSLTLKQNEVLPGAKLDVDGQIDSFHLFLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSMGVSSEKSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPHMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFADHKEQPVRGPAFQSDVVHPASLQKAALSSRSASVDESRPEFICRLALGIFSVSVLHIDPLSPAETSLNVNPLTRMATDFFSCVEKMDPAIFSTGDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRHFSTDMSVGQMEFLECLFPTDCHSVPSHYTELLTFHSKEGTDAHLPVCLQLHYKHSETRGPQGNQARLSSVPQKAELQIKLNPVCCELDISIVDRLNSLLQPQKLTTVEMMASHMYASYNKHISLHKAFTEVFLDDSHSPANRRVSVQVATPALHLSVRFPIPDLRSDQERGPWFKKSLQKETLHLEFTDLESKTEFVGGSTPEQTKLELTFRELSGSFQEEKGGPSVKFFHVSGGVDGDTASSDDFDWPRMVLKINPPAMHSILERIAAEEEEENDGHYQEEEDGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELLLPNIHLTLPNKGFYEKLYNRIFNDLLLWEPTAPSPVETLENVSYGIGLSVASQLINTFSKDSFSPFKSAVHYDEDSGSEEETLQYFSAVDPNYRSRRKKKLDSQNKNSQSFLSVLLSINHGLMAVFTDVKQENGDPMESKHGEFWLEFNSGSFFCVTKYEGFEDKHYICLHSSSLRLYHKGIVDGAILPTETRLPCSTRPHWLEPTIYSSEEDGLSRTASDGVGGDNLNMLSVAVKILSDKSESNTKEFLVAVGLKGATLQHRVLPAGLSWHEQILNFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLHLPLRSLLTVETFSISSSVALDKSSSTLRIIMDEAALHLSDKCNTVTVNLNRDYVRVMDMGLLELTITAVKSDSDGEQTAPRFELHCSSDVVHIRTCSDSCAALMNLIQYVASYGDLHGPHKAEMKPGVPQRKPKVDSSARSSSHGPVLPEADQQILRDLMSDAMEEIDLQQASAPVGPQANGVLDEKSHTQEPCCSDLFLFPDESGNVSQESSPAYPSLTHHLISDAVTGVTAENDDFCILFAPKTVVQEKEEEPVIKIMVDDAIVIKDDYFSLPITRTDSSKAPLHFPIPAVRYVVKEVSLVWHLYGGKDFATAPPTSPAKSYISPHSSPSQTPTRHGRHTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPECESSLLEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKDMPRKAHSNMLTIKALHVRPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSTEVELLLTPDPEVTKSPGADVTCSLPRHLSTSKEPNLVVSFPGPKQASPNHRANSAEGGNGLEEDVSAEETSFSDQPVFFREFRFTAEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLFYRHGLLGIDKLFSYAISEWLSDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPSTLSIEPKKAKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVRPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGED,XP_006516424.1|MAVFTDVKQENGDPMESKHGEFWLEFNSGSFFCVTKYEGFEDKHYICLHSSSLRLYHKGIVDGAILPTETRLPCSTRPHWLEPTIYSSEEDGLSRTASDGVGGDNLNMLSVAVKILSDKSESNTKEFLVAVGLKGATLQHRVLPAGLSWHEQILNFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLHLPLRSLLTVETFSISSSVALDKSSSTLRIIMDEAALHLSDKCNTVTVNLNRDYVRVMDMGLLELTITAVKSDSDGEQTAPRFELHCSSDVVHIRTCSDSCAALMNLIQYVASYGDLHGPHKAEMKPGVPQRKPKVDSSARSSSHGPVLPEADQQILRDLMSDAMEEIDLQQASAPVGPQANGVLDEKSHTQEPCCSDLFLFPDESGNVSQESSPAYPSLTHHLISDAVTGVTAENDDFCILFAPKTVVQEKEEEPVIKIMVDDAIVIKDDYFSLPITRTDSSKAPLHFPIPAVRYVVKEVSLVWHLYGGKDFATAPPTSPAKSYISPHSSPSQTPTRHGRHTVCGGKGRNHDFLMEIQLSKVKFQHEVYPPCKPECESSLLEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKDMPRKAHSNMLTIKALHVRPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSTEVELLLTPDPEVTKSPGADVTCSLPRHLSTSKEPNLVVSFPGPKQASPNHRANSAEGGNGLEEDVSAEETSFSDQPVFFREFRFTAEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLFYRHGLLGIDKLFSYAISEWLSDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPSTLSIEPKKAKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVRPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGED
2	ATG2	855479	Autophagy-related protein 2		APG2|AUT8|SPO72	baker's yeast	NM_001183080.1	NP_014157.1	NC_001146.8	P53855	Preautophagosomal structure membrane.	NULL			Required for cytoplasm to vacuole transport (Cvt) vesicle and autophagosome completion. Necessary for the localization of ATG18 to the preautophagosomal structure (PAS) and the binding of ATG18 to ATG9. Involved in correct ATG9 trafficking through the preautophagosomal structure and in peroxisome degradation. ATG2 is the most downstream ATG protein in the preautophagosomal structure organization process. Plays a significant role in life span extension. {ECO:0000269|PubMed:10029994, ECO:0000269|PubMed:11382760, ECO:0000269|PubMed:11382761, ECO:0000269|PubMed:11675007, ECO:0000269|PubMed:14723849, ECO:0000269|PubMed:17295840, ECO:0000269|PubMed:18586673, ECO:0000269|PubMed:18625846, ECO:0000269|PubMed:19371383, ECO:0000269|PubMed:19995911, ECO:0000269|PubMed:22728243, ECO:0000269|PubMed:23230146, ECO:0000269|PubMed:23337777, ECO:0000269|PubMed:8224160}.		8849441,9169873,10900456,11382760,11382761,11689437,11805826,11805837,16554755,17295840,18497569,18586673,18701704,19793921,19840948,21887408,21987634,22199229,22728243,22768199,22842922,22851171,23230146,23382696,23409723,23549786,23904270,24440502,25026036,25468960,26061644,26181331,26493364,26673895	28	1->166,217->419,470->482,577->669,755->782,914->1202,1246->1259,1382->1483,1524->1540,1572->1592	NP_014157.1|MAFWLPQNIQKRLLLYVLQQISLFSNIDLSNLDVSIGSKSHFSFHDVNLSLDDLNIPNVQINEGIVDELVLKLTVSGGVEIDGSGLRFIMTPLYSSGSQELHSDFLVKSIQDLTNSMLQFSDPLTTYNRYKEDDISSSDSSSDLNSNIEASKPAANGSYTLQNMRNKALNVALAKLKIALKDVTIRFIVNDRDPSDNIVEVHLESIQLITTDANLRHINIENITISSIQKQAVPDSPVHPFNNDDLSQSVYLSKMEATSLYMSAMEEQSNEDPSEPQVTQEEQENDKCKESLMEINNLNIAFKGLSSVNDLRMSNIVIDIQDVHLAIHKIVEIKNSTLKNIIDIIVTHLDANESFSCQDSQSPSPDKQEPSALSSVDIKCIYLNLGQDITVILKSFKLEQKENNSLAFSLGSFYSNSSPLTISHKTKPLLTGEQTPQSIALNMGDELDIIISHDGIAHFFKIFQFVSKCMSFYQNKSKGMMPQIASDTKRTVQLTSKAVKLSLKFPYFLLCFQVSPFIYDSNRELYIELVDVFKKLPSRCTKILTMSSITISNLQSPLQLGSYDDTLKEALIYSSVHAIIKEVIFNEEYSGIVQLVEDISAFGKLFTDSKNSECTGKSKSKRGSFLQRSVRVLNSSRFVYKQSLSANFSLKIDSMKLKVSEIIGPQFGSVEALLSNNFFAITDDSQIVYFTKNLKVERKTPSLLEPQEIMSVVLNKAVNEPVLYVHRRANGKLKVIFNNIRIHYYARWLEILKKNIGPDNASSKDEPVSQKLSKKQPTSGFPWELKCLDCSLILHPFRLKSVMVIVLDNLTTGGSSFIPQAKLLSKANTLFLIDDYQNFKIQKDKNWPSLINFYAGQGFSAIGKIDTLNFLINKSDGALLLDCKIEQVGLSLCADSFQTFCQLCIDLKYPQTFPDEEKFRTQLKNPIDVFKDIDCDLFNSAFIRENNHQNDYDSVHLVDSFLDKTHEFNNGARSKLSSQGSYEMDSSSGTATGGILLPHESYLDSAQPKEEDTPPIASKEQERDVDIRGSIDVEKVVIKLFDGYDWKYTRKFIANTVEKLDKELSKAEASSSKSNVPQSEANIFDSIYISANKNNVTDLRRNLDGEIQGVQNSFSDVSKVNLRPSKHYKALIQLNKVHVNLKNYRVDEPDESNSDNSTDVLNRCVVSIYEFEIIDNVPTSTWNKFVTLLKHEPWPHSSPMFLLDLEFIRPIDFLQAVELVMQLNVAPLRLHVDQDTLEFLIRFLGFKDKRFELIDEYPDIVFIQKFSTNSIKLRLDYKPKKVDYAGLRSGQTSELMNFFTLDGSKIILKSVVLYGLNGFDELNNKLKAIWTPDITKKQLPGVLEGLAPVRSFMAIGSGVKTLVTVLMSEYRQEGHLGRSLKKGGNVFLKTTTGDFVKLGVKLTSGTQAILENTEELFGGVGSNGRVYDASKFGSADGADSDTAAVLDLDTLFEEDQLVGSKYSRIRDHEPTAVVIDMSSPGDHNEPTIVSLYADQPLDLPTGLKEAYSSLEKHMHIAYDAVWRAKGQMKDDKRGGPSAAAVYVARAAPVAIIRPLIGATEAVSKTLQGIANQVDKTHNEQINDKYKSNRTDS
2	VOLCADRAFT_105023	9615341				volvox	XM_002951135.1	XP_002951181.1	NW_003307565.1	D8TXV2	NULL	NULL				Vca.10068	20616280	81		XP_002951181.1|MFEAQVAYYLNKYLGQYLQGLDADSLRISVWRGDVELRNLSLRPEALQDLDLPVTVKAGLLGRLTLKVPWTALGREPVVVEFDRLYILACPKDQTPGQATQVNVSQYEADVAAGELEAKRRRVMEAETQWLQFMWGGGRGGASEPPFSLASTSTSGTLLPWQQLHSLVVRLFPPELQAKLILKAQQQQQQQQQQQQVSSDGKAGGDTKGKSKSRGGGGLFHLNLTALIHTILGNLQLRLTNVHIRYEDSSSLPGGQRLAGGILLGGVSAHTVDETGREAFITNDVLNLLRKAVVLQELGVYFDMGSPFLEAPRDWSALMAREWDLLFSPARHAPGSGDGGSGGDGGNGGPHYRHHYLLLPISGQMNYVRRSAKVLLADTSSAGGGGGGGSGGGGGGGRPPRQEGRIALRAVSLALSRDQYVGARALLETLDSYTANAPYRVMRPQCRPAPGAAARVWWRYAFLAVRKQLRLQRGGSCSWSQLQTACRLRKKYVPAYARCLMAASAASTSTAASGRSGGGGGGGSSRSPERQPPASAMASAGGLGGDATIAEMDAQLPEGTILLFRRMAHAMAQSQRPATTGGGVQGQPAVAAGAAAPAASTSTSSGGWQEDADQDEEEEEEVEPGATGGGGGDHPYCLTALLEVAVERCSLELGMSAADGVQPLISASMQAVGLRVLRYPQTLGVSLRVGWAGLDSPQGMLLCTGQLQNNSPQQELAYGTTLPAISGGGSGSGGGGGDSGRPRMSVKELKGEGKGVSGGKGGSESRPGTPSMPAAVITGSSVGGGDAGGDGSGDDSYQPTCAFMLDFVRRPQDGSADATLSVRLAPSYVTYNAAAVAAVGAFFSSSQQIGQLGNLQAQAAARVQRLQRLAQVRLRALSRERPKMVLRVVMHAPKVALPDDKGRGTLLLDLGCFSLSSSTPKAQGLVPSSDEASLYECFNFGIQRVEAALVGGRFAWPATSPQLPAALEEVAGGAVAASAAAASAAAVAAATFALLGPLPAGPDAREDRRGGRGAGGGGGGGSTAPLGLAFVAALAKEGPVAADELPPEGTHDSGEPPAAASSRSPAAATPPAPELCYESHDDDDSDGGSSLVELVRHIAGKDETSSSPPVVVTLLPRFGAQAELQVAAAQDPRLPAVRLRVVASPLRVEFSPWRYHRLMAVIGSLTASGSHGDPTGEAGGCWSSNRTRWVGGADNAVALVPEHVAVRREAVAESPEALVMRLGDSGEVAALRRSLARSAALVESVAGLLGAEAEDAESDSVAGQDLAKAGGGAGSGAGGGGLGINRDLLDELLAHRDVFELTGSLPSLEVRLSGRPPRAWRAVRRLAAAEPPPPPGAVDINAAAGGTGEVLGSMYQPSESHAGTDLEGTPRRPGGSVSSLSDFAGGASASAASPSLAAATKQPGRPGSSSSRFGGGGGGGGEVETASAAPPPQPPPQPQPVNTVGPTSSLHGSRVGPGSETESDVEFVDAAEYDNDDVDGGGSTYGVGGGDEHDGGDHEDHDHHQRLQDLTLEQEVPLLGVALTSAAVRVQYSADRLAVSLRMHGLRVENELMGSALGKQFAVLAVSSSLCTSTSATETTGAVDAAAASAGGEEKAATEGTDVESSSPLVQLSFTSNSSKSDRYKGLDTEICLQLASLFLTCHRPTVAALMGLGADMAYANSRLAEDKNADAAAAAAEPLPPAPSAAAAPAAAAAVVRSGGEGRTLMRLRISMARLQLVMPYEVLLPVQLPTAPSPPTIAHAVQQPPRQQEQQEGSVREQAAAGARSGPGPRLLAVAEMDAFSFCLDVRPSSLELTTSLGNFTAQYGALPASSPYRTICTMRSGTSGSLIEVAFRMHSAAESYSQPRVPPGQPYSSLSASLSAVQVVYMGRFLNELLSYLTAASSSAAVPATAAAAVAATSGSAGATADTAGTPMVLLLDVSLASPDISLPQNSSSGLEHRVGIDLGTLRLSNSVAWRRGVAAAAAASRAGGGVTTAGVDIAAPGAEGWEVLMDEMKIHLTDMSLVVGHADEGDGGQAYAGGSGKGQNIIRDVGSGVTVSLHRPLAIKPVGPAAATTDIEGTAAAAAAVPPPMPPLHAAVTLPQLSAVVSETEYRRLLAVLSGNFSEVAQNDPRVTELHQILQRLGGASSPPPRPPPPPPAPLSPHPPLTVPSPVKSTSTAAGGGGAGGGGGGNGVLRSPVLDFTRSIRSVLAALGDNCTVQATVAVGTARLTLLMSAAADGGGALAPLTAVDLRDFWLGYYATARGGMFLSATLPTFTIEDLRPGVSLEQRLVLSTAAAAVAAADGGSRGPSAPSQPQTLSHSAPSPSLLALEYRSSPGSTEVHGGNGAGTATAFPAVQALKLRLQRPTLVLDFGLLLRLVNFVTPSPVLQYPSIQGVPVHPRYQLPTSVVRLSLPSQPCDMWQALTSIFRMFGRFPFPCQGATPRPYETRDITVPLHMPYSAYGNDLWLSPEVRLLADAPAAGAAPPATGFLHVYDGGGGRLVLPPGLSPVESLPLIVVGANRALKLKNVRIVNCASLPSCLSLGPGAQLQARDEDGVKFILADPEVDRQYGAVMAAAAEVAAAAAAPAGAAGGSIAVTAPPADLVPATVPPPPPVFEMSVDALGVSLHLIEAPSRGIGAVLDENGGDGQPYGSSGYGSALDLTLGLTSATATPPRPPRLGADADATSALGGAMAQRLRRRLVLQLDASAKVTMQGQRQEAAATLRSLTMRTVTIFPTAAAATATAPVAASPPPSKVGSVSNLAAAAGCGIRPAAAPPEAAPTAPAMTIATSLLEPTDIEMRYSLSSSNQDLSLDVDALTLRLSPAALHLLLQLQELVLQPLAAPPPDKPLTRCDRFERLWSSHWGAPRTATAGATAPGGGGGGGGGGGGGGGRGPRGLELGVGGVDSLAEERGVTVWRPQPAHGYVALGDLLTAGTRMPSCQVATLAINSGLVAFPVAFEPVWLGPEAEDLALWRPVGPPGYVALGCVAGPRAAPPPLAAVGCVAARAVVEARLGECLLLTDRGNLWAVQNAAASFEVSPTEKHLPVVHLYDLRIPLGVPPAALTPLPQLLPTAAAVVPLGLVREASLPLGLGAASEPPPLSLLCQQRYLRSRSALIRRALSQASQLPCVEFTRVWWDKSLPAPSANRLSIWRPNPPPGYVFLGDCAATGIYAPPPSVVVLRDSDPGAALRDGRPPPLARPINFIRVWVDEHRERQGDPGALVLWRPVPPAGYVPLGLLAGLGSARVPSVQIPLRCVRADLVTSETLSRSAPDWHLPAFRHRTPLSGWLTDRRTGTFTVMAGPGAAPGDSSVGGGGGGGGFSEGFGGGTGSPAGKSFGQGQQGQGGGATFDAYRMKLDADDPWVASPGAGGGNGGGAGGGGGGAGGGDGTGTAGAGVTWGPIPGAVMAGKVTGAPRAYVFPDLSRSYAYLTVSIWTHSPSLGVWEPLLEPWAVLAHLDDNRTARPVAGVSPGTTIRITSTQSSVQVALAATALKSLLEALPEWTGLTSPEGLAAVRRQLAYGEAAAGGSLYGSLAAQQGLMTNALGCPVSLLTDLGDRQAVVELQTDAEDVPVLLQPPPTAAAAAAADSRAAGLAPPPVPAVRMFVDAVSAGPLPAELLREGGLMVRIKVKRQAPKGAAGRDVEGGSSEGRRVGTPITDSVVRWDERFLLKLPVELSEQLLCPAPGDNQFAGVPLQVDDSWEGLGASDWLANEVDTLRNTAAAAAAAAAAAGTLLPVLGAAAEGGGGAGAGGAAGGGSDVSETVDVPLFPTRVVVAVHNGDGGGVGGRAKSGGRPVGRARGDEAPVMLQLRLSLDVHQVDSSWQPFLSRTRRRLPYASPDGGPGGGSEGRTGGAVAAAAAIRGGRRAVRLYGSDVWVPFGQTGGIIISGPGGDMLQASSCIPIRAGPGLVLERSPGPGGQPLELLRSLAVLVNGSGVPLEVSLVAGDPEVASWTMLAGEAKPPPALPSAAAAAAAAGGHAEAATAAAPPPSPVEEDVYENERYIPLFGWSPNNLLPTERRRYSRHGQSYTSFPLVPLPPGWEWEGPWQVENAGHVDANGWFYALDWPLLRYPPTPEQARRKVTDMVRRRRWLRRRRWVGVGSGAVKGAAAVDGGPPRRLLGVVSPSDKLPLPLGWEVEGVELQVRPVAATSTSTSTAAAGGLGDTEAHESHEWSAGLVMSGLDEGGARLLCCRPMSALPNPGSEITSSTSATTGTASTSAFAGLALMPVAEAEEAATAATAPSAPPPLVDPLHPAWLSVSLECEALVATSGFLSGPGGGLDTLVDWRLVVRPPLTVHNTLPVAGRYIVWERDGRVGAREPPRVRQSGRVAAGGAAPVFSADMRMQASPHVYLSFAPDGCEYGESSPVIISDGYMRNAAGVAAAPRLPDSFRCTYSHSASFSALRIQLIRDVDTSAASAGFLAASAGGAGASRRGGGGGGLLFSPGEAVARGYPLTVSLHVPIWLVNATQLPVSCGILEVEAPPAPPSSMAAGVGGEGGGGGGGGGGGIRPELSAVSSGVGGFGATNQPPPHVLRIIDTEAFKNSPRPQSYVSVLPRSLELLSYPAGVTGPLESGDGDGGLQVAVVLRLHDSRWTQPIYLPRPGEQMQPRPGAGGVPLPSDRLLVRALCTDGCIHEVAVRLESAPLGLGLEFGLGLGTGLGAGLGAGLTTAGGLGGVAAATRASVAVVVRLEHHVVLTNTTGYPLQLLQPELAASADLGGGAGGRGFRGGAGMTFTAGGGAGRGSASGTTAAAGAPSLAAALTMSLPPGSLGVPLRWAAAAASRRHLCLALPLAGETATSATAYGLSPSIMWSEPLKIDMPGGQDAQVAVPVYCLGPVGRYHSAHASGPAAGALAAVAALANMTPQQQRLFELQRAHTVARAMFASLCGGGPGGGGGLLRLTRHASSGEDGGGGGGGGGGGGGGGGGEEQQQHQQQQGGEAAATWMARGVPVGASPPGRLHPPSLEPNLVRIVRPTELGNVEFLAVLLNVRLVMRAPGCLVLRLASLGGQPQQLLHNTSPHDLMWRQASPRAAWARLPGYSAAAVARGVLGESWGSPVEVELRDTEPQSESSLLLTTDLMAVGTGVSAGVGGFPGRGGIGGVGGGVGGGLLAAGGGGGGGGGGPLGAAAGDLGRPVLQGIFSVGQKHREVMAQVAGGWGGKGEGEGEGKLTAGRLTRVLRVGRGKGVDFMHLSLRLRSAQLDDQVPGSAYPVVLQPLEQPGGGGTSDPLFVLQYCCQFQFQFQFQFQFPVSGSDLPMAIDLLVVEDLVLRCSFRADAASRPRWAAGGFLKLGLDLAQLEDLSLVLPGIEVERTRLLRSELLKKVYDRLQERVFSLALAVLRSAGLMGGLSKVRSLQGGVLEGGKLIAKGFLQGATGIITKPVEGAERGGLSGFIGGLAKGIVGAAVNPVSGALAAVSKVTEGADATRRNIAGVLTGAAGVRRAGVGRKRLQRAFTGDNVLRPFKLHSALGQALLYSVAAWTGPSNPASGNDPRVAGGGAGGSGLLGLGAAGLGLVGAALPGSVRGGAGARPDLRQDRYEQHWILPGAVVLLITDRRVLAMRAAEFCALQERALAGDIAHVTDVPVSDAVVLWHLPWPEMLSAELAWFERPDRAAAESAGRSAADGLVLHRKHKSEGDRLYYEVHCTPGSAMAAEIRNRLQEERGWRDSQPQQMQLAAAAAMAAAAAAAAATTTAATAGSRSAAALPTSSAAAASSGSVNHYRSGTGGPDVVLPDTTLSQDFKLVWAATGSRASGGRSMSIWRPVGPPGYVALGDVAVTGREPPPRPVRLYKDSPALAAAAVNASGSGDAPASEAPRLAPPAGYSLLFRDSARPPLTLWRPEPPQGYVEMGCVAWPEIEEPPLGLVRCLRKDLVGPGRVFDSPVWAGGSGDNPYWKVSMWPVDCPAGTFVAVPFEVSKKPTRVFEAVF
3	atg-3	176921				nematode	NM_001307469.1,NM_067623.4	NP_001294398.1,NP_500024.1	NC_003282.8	Q9N369,U4PRD2	NULL	NULL				Cel.11917	9851916,18006689,22862955,23530068,23619095	5		NP_001294398.1|MGYDENRRPLTVEQTYEDFSADHSNKTITVEAHPSVDLTMPTVHPCKHAEMMKRLINQYAESGKVLGVHEYLFLFLKFVQAVIPTIEYDYTRAIKL,NP_500024.1|MQNLVNNLKSAALQIGETFTPVLRESKFRETGVLTPEEYVAAGDHLVHHCPTWKWAGASDPSKIRTFLPIDKQFLITRNVPCHKRCKQMEYDEKLEKIINEEDGEYQTSDETGWVDTHHYEKEHEKNEEKEQSTAPPPAAPEDSDDDDEEPLDLDELGLDDDEEDPNRFVVEKKPLAAGNDNSGEVEKVRTYDLHICYDKYYQVPRLFLMGYDENRRPLTVEQTYEDFSADHSNKTITVEAHPSVDLTMPTVHPCKHAEMMKRLINQYAESGKVLGVHEYLFLFLKFVQAVIPTIEYDYTRAIKL
3	ATG10	83734	Ubiquitin-like-conjugating enzyme ATG10	ATG10	APG10|APG10L|pp12616	human	NM_001131028.1,NM_031482.4,XM_005248610.3,XM_005248611.3,XM_005248612.2,XM_011543660.1,XM_011543661.1	NP_001124500.1,NP_113670.1,XP_005248667.1,XP_005248668.1,XP_005248669.1,XP_011541962.1,XP_011541963.1	NC_000005.10,NC_018916.2,NT_034772.7,NW_004929322.1	Q9H0Y0	Cytoplasm.	NULL			E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. {ECO:0000250, ECO:0000269|PubMed:21367888}.	Hs.713698	2890687,8125298,11076863,11230166,11256614,12477932,12482611,12890687,14702039,15489334,15489336,15498874,15657430,16381901,16963840,17256008,17353931,20379614,20562859,20723759,23285162,23850577,26186194	15		NP_001124500.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,NP_113670.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_005248667.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_005248668.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_005248669.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_011541962.1|MCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_011541963.1|MLEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP
3	ATG3	64422	Ubiquitin-like-conjugating enzyme ATG3	ATG3	APG3|APG3-LIKE|APG3L|PC3-96	human	NM_001278712.1,NM_022488.4,XM_011513074.1	NP_001265641.1,NP_071933.2,XP_011511376.1	NC_000003.12,NC_018914.2,NT_005612.17,NW_004929311.1	Q9NT62	Cytoplasm.	NULL			E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12- ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. {ECO:0000269|PubMed:11825910, ECO:0000269|PubMed:12207896, ECO:0000269|PubMed:12890687, ECO:0000269|PubMed:16704426, ECO:0000269|PubMed:20723759}.	Hs.477126	11825910,12477932,14702039,15144186,15355958,15489334,15592455,16303767,16704426,17353931,18083104,19342671,19838173,19932681,20061800,20562859,20697744,20723759,22644571,22863883,23119048,23824909,23829686,24023838,24186333,24191030,24420857,24747438,25147182,25503391,25689150,26043688,26496610,26673895	15		NP_001265641.1|MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYPSLYVRLVAKWLLTIFFLRNLV,NP_071933.2|MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM,XP_011511376.1|MEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM
3	Atg10	66795		Atg10	5330424L23Rik|5430428K15Rik|AI852123|APG10|Agp10|Apg10l|Apg10p|Atg10l	mouse	NM_025770.3,XM_006517326.2,XM_006517327.2,XM_011244551.1,XM_011244552.1,XR_873450.1	NP_080046.3,XP_006517389.1,XP_006517390.1,XP_011242853.1,XP_011242854.1	AC_000035.1,NC_000079.6,NT_039589.8,NW_001030534.1	A0A0R4J029,Q8R1P4	Cytoplasm.	NULL				Mm.235385	8889548,10349636,11042159,11076861,11217851,12466851,12477932,12482611,12890687,14610273,15033168,15489334,16141072,16141073,16602821,18799693,20723759,21267068,21677750	19		NP_080046.3|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE,XP_006517389.1|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE,XP_006517390.1|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLGTSNTWATIFCSTSLQDK,XP_011242853.1|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE,XP_011242854.1|MCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE
3	Atg3	67841	Ubiquitin-like-conjugating enzyme ATG3	Atg3	2610016C12Rik|APG3|Apg3l|Atg3l|PC3-96	mouse	NM_026402.3,XM_006522495.2	NP_080678.1,XP_006522558.1	AC_000038.1,NC_000082.6,NT_039624.8,NW_001030584.1	Q9CPX6	Cytoplasm.	NULL			E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12- ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. ATG12-ATG3 conjugate is also formed upon viccina virus infection, leading to the disruption the cellular autophagy which is not necessary for vaccinia survival and proliferation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. {ECO:0000269|PubMed:11825910, ECO:0000269|PubMed:18768753, ECO:0000269|PubMed:20723759, ECO:0000269|PubMed:24089205}.	Mm.41775	8889548,10349636,11042159,11076861,11217851,12466851,12477932,14610273,15489334,15782199,16141072,16141073,16602821,18083104,18768753,20723759,21220506,21421856,22024753,22055190,22170151,22493260,23184977,23202584,24035364,24089205,24191030,24466199,24591649,25686249,26027738	19		NP_080678.1|MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTDKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLESKDSIKLQDCSALCDEEDEEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM,XP_006522558.1|MEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLESKDSIKLQDCSALCDEEDEEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM
3	ATG3	855741	Autophagy-related protein 3		APG3|AUT1	baker's yeast	NM_001183184.3	NP_014404.3	NC_001146.8	P40344	Cytoplasm.	NULL			E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. The ATG12- ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. {ECO:0000269|PubMed:11058089, ECO:0000269|PubMed:11100732, ECO:0000269|PubMed:11149920, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:12965207, ECO:0000269|PubMed:15277523, ECO:0000269|PubMed:17227760, ECO:0000269|PubMed:17632063, ECO:0000269|PubMed:17986448, ECO:0000269|PubMed:18544538, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:19285500, ECO:0000269|PubMed:20615880, ECO:0000269|PubMed:22240591, ECO:0000269|PubMed:22539722, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:23503366, ECO:0000269|PubMed:8050581, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:9023185}.		8849441,9023185,9169873,10688190,11100732,11139573,11149920,11283351,11805826,12965207,14562095,15277523,16319894,16429126,17227760,17923092,17986448,18701704,18719252,19285500,19303850,19793921,19840948,19841731,20093466,20615880,21228276,21232131,21460040,22055191,22056771,22240591,22325599,22539722,22768199,22993095,23142976,23332755,23503366,24586198,24879155,25042851,25461810,25631054,25645919,25680528,26061644,26493364	28		NP_014404.3|MIRSTLSSWREYLTPITHKSTFLTTGQITPEEFVQAGDYLCHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPCDKRAEQCVEVEGPDVIMKGFAEDGDEDDVLEYIGSETEHVQSTPAGGTKDSSIDDIDELIQDMEIKEEDENDDTEEFNAKGGLAKDMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKVRVVRQRRRKELQEEQELDGVGDWEDLQDDIDDSLRVDQYLIVFLKFITSVTPSIQHDYTMEGW
3	apg3	9627481				volvox	XM_002952471.1	XP_002952517.1	NW_003307573.1	D8U1M2	Cytoplasm.	NULL					20616280	81		XP_002952517.1|MNVKHTLHTLFKSAVEKVAPPLSKSQFEEKRVLTPEEFVAAGDYLVHACPTWSWEGGDPKKRKSYLSAEKQFLVTRNVPCLRRATDVAGGSSYNPMSEFALPGEEGWVATHIQPTPGGAGTGPGGDADIPSMDDDEDSPLQAGPAAAAAGADAGGGGGGGGGGKEREKEKDGEGDIPDIGDLELNEGDDEAAAPSASAAGYLRAEEPADNIVRTRTYDLYITYDQYYQVPRFWLVGFDESRKPLLPHQGIGVMEDVSEEHARKTITLDPHPHLPGLSAASIHPCRHAETMKRLADKLVEGGRDFRVDLYLVLFLKFIASVVPTIQYDYTMAVGGD
4	atg-4.1	190777				nematode	NM_001276646.1,NM_060974.4	NP_001263575.1,NP_493375.2	NC_003279.8	K8ESC5,Q9NA30	Cytoplasm.	NULL				Cel.16270	9851916,14704431,19123269,22767594,22862955	5		NP_001263575.1|MLSILPLAYSNFSRILQYFEQLPVVDKMTEEILKQGVGIVETSLTFEPPFCESFERISIDNFPIFALGKEISKEDGIEAMKKYVTSRFWFTYRRDFSPIGGTGPSTDQGWGCMLRCAQMLLGEVLLRRHIGRHFEWDIEKTSEIYEKILQMFFDEKDALYSIHQIAQMGVTEGKEVSKWFGPNTAAQVMKKLTIFDDWSNIAVHVALDNILVKEDAITMATSYPSEDAVKLIMENGLVDKNRLSLSPGNIIPEWRPLLLMIPLRLGLTTINPCYLSAIQEFFKIPQCVGIIGGRPNHALYFVGMSGSKLFYLDPHYCRPKTESTAKMYAEKDSTATTDDVGFSHLEELVPLPSQTADVYTKMDDSTYHCQMMLWIEYENVDPSLALAMFCETRDEFENLCETLQKTTLPASQPPMFEFLQRRPKYLPKFEPYTGVSMKIEMKEFDDIGAANVKIDDDFEVLDVHTEEEDADEDNDDDVANA,NP_493375.2|MTEEILKQGVGIVETSLTFEPPFCESFERISIDNFPIFALGKEISKEDGIEAMKKYVTSRFWFTYRRDFSPIGGTGPSTDQGWGCMLRCAQMLLGEVLLRRHIGRHFEWDIEKTSEIYEKILQMFFDEKDALYSIHQIAQMGVTEGKEVSKWFGPNTAAQVMKKLTIFDDWSNIAVHVALDNILVKEDAITMATSYPSEDAVKLIMENGLVDKNRLSLSPGNIIPEWRPLLLMIPLRLGLTTINPCYLSAIQEFFKIPQCVGIIGGRPNHALYFVGMSGSKLFYLDPHYCRPKTESTAKMYAEKDSTATTDDVGFSHLEELVPLPSQTADVYTKMDDSTYHCQMMLWIEYENVDPSLALAMFCETRDEFENLCETLQKTTLPASQPPMFEFLQRRPKYLPKFEPYTGVSMKIEMKEFDDIGAANVKIDDDFEVLDVHTEEEDADEDNDDDVANA
4	atg-4.2	3565022				nematode	NM_069807.3	NP_502208.1	NC_003282.8	Q9U1N6	Cytoplasm.	NULL				Cel.32682	9851916,22767594	5		NP_502208.1|MNNIPDDFKKIASSSRLPRKYCSSESSLSDDDGHEIEHVLKHGAPEEALTPDTERMVVLGQDVVQSAPASLVPGGNLSWMSKIKSAGASMMGSIRPSSSSQDVHSTGEIEKHSKKKWKARLWSTWNNIKYSSTWMSDRSDEYGGENDVVFLGRRYSTSVDESGLRSGFENFCSDYYSRLWITYRTDFPALLDTDTTTDCGWGCMIRTTQMMVAQAIMVNRFGRDWRFTRRKRSHVAAHGDEDDFDREKIQEWMILKLFEDKPTAPLGIHKMVGIAAMGKGKKAVGSWYSPSEAVFIMKKALTESSSPLTGNTAMLLSIDGRVHIRDIEVETKNWMKKLILVIVVRLGAAELNPIYVPHLMRLFAMESCLGITGGRPDHSSWFVGYYGDQIIYLDPHVAHEYIPIDINPNTNVVDSDSKKAKKCPEKSYHCRLLSKMHFFDMDPSCALCFQFESREQFDNDMRQLNLSQFIDIDQGEEHGMKRVRDPMFSVVYGERRQPPSYEREVSETEQAQADKHGFEML
4	ATG4A	115201		ATG4A	APG4A|AUTL2	human	NM_001321287.1,NM_001321288.1,NM_001321289.1,NM_001321290.1,NM_052936.4,NM_178270.3,NM_178271.2,NR_135608.1,XM_005262064.2,XM_011530840.1,XM_011530841	NP_001308216.1,NP_001308217.1,NP_001308218.1,NP_001308219.1,NP_443168.2,NP_840054.1,NP_840055.1,XP_005262121.1,XP_011529142.1,XP_011529143.1,XP_011529	NC_000023.11,NC_018934.2,NT_011651.18,NW_004929444.1	Q8WYN0	Cytoplasm.	NULL				Hs.8763	12446702,12473658,12477932,14702039,15169837,15489334,15772651,17207965,17347651,20010802,20819778,21122541,21177865,21297227,23508006,24100292,24229464,24256813,25416956,25426560,25490467,26186194,26496610	15		NP_001308216.1|MLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,NP_001308217.1|MLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,NP_001308218.1|MLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,NP_001308219.1|MDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,NP_443168.2|MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,NP_840054.1|MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,NP_840055.1|MLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,XP_005262121.1|MLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,XP_011529142.1|MQSTGSSVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,XP_011529143.1|MQSTGSSVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV,XP_011529|
4	ATG4B	23192		ATG4B	APG4B|AUTL1	human	NM_013325.4,NM_178326.2,XM_005246992.2,XM_005246993.2,XM_005246995.2,XM_005246996.1,XM_011510836.1,XM_011510837.1,XM_011510838.1,XM_011510839.1	NP_037457.3,NP_847896.1,XP_005247049.2,XP_005247050.2,XP_005247052.1,XP_005247053.1,XP_011509138.1,XP_011509139.1,XP_011509140.1,XP_011509141.1	NC_000002.12,NC_018913.2,NT_005403.18,NW_004929308.1	B3KVU2,Q9Y4P1	Cytoplasm.	NULL				Hs.283610	10231032,11076863,11230166,12446702,12477932,14702039,15169837,15187094,15355958,15489334,15489336,16169070,16183633,16325851,16381901,16704426,17081983,17353931,18083104,18387192,19322194,19549685,19615732,20010802,20562859,21177865,21900206,22658674,22674379,22939629,23508006,23535732,23824909,24023838,24755409,24991826,25126726,25490467,25652856,25689150,26186194	15		NP_037457.3|MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEILSL,NP_847896.1|MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQILLM,XP_005247049.2|MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGGTICALASPVLAPLVLTIKVCVSLSREHLAVVRL,XP_005247050.2|MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGDSSDVERLERFFDSEDEDFEILSL,XP_005247052.1|MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGGTICALASPVLAPLVLTIKVCVSLSREHLAVVRL,XP_005247053.1|MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEILSL,XP_011509138.1|MWPLALLSPKRGDRPHLGHRLGLHAAVWTDDLCPSPGVPAPRPRLEVDTKEEAARQLLQRPQRIHRQEGQLLLHSPDRKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGGTICALASPVLAPLVLTIKVCVSLSREHLAVVRL,XP_011509139.1|MWPLALLSPKRGDRPHLGHRLGLHAAVWTDDLCPSPGVPAPRPRLEVDTKEEAARQLLQRPQRIHRQEGQLLLHSPDRKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGGTICALASPVLAPLVLTIKVCVSLSREHLAVVRL,XP_011509140.1|MWPLALLSPKRGDRPHLGHRLGLHAAVWTDDLCPSPGVPAPRPRLEVDTKEEAARQLLQRPQRIHRQEGQLLLHSPDRKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGGTICALASPVLAPLVLTIKVCVSLSREHLAVVRL,XP_011509141.1|MDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLGESCQVQVGSLGGTICALASPVLAPLVLTIKVCVSLSREHLAVVRL
4	ATG4C	84938	Cysteine protease ATG4C	ATG4C	APG4-C|APG4C|AUTL1|AUTL3	human	NM_032852.3,NM_178221.2,XM_005271288.1,XM_011542313.1,XM_011542314.1	NP_116241.2,NP_835739.1,XP_005271345.1,XP_011540615.1,XP_011540616.1	NC_000001.11,NC_018912.2,NT_032977.10,NW_004929290.1	Q96DT6	Cytoplasm.	NULL			Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. {ECO:0000250, ECO:0000269|PubMed:21177865}.	Hs.7353	8889548,12446702,12477932,14702039,15489334,16344560,17442669,18029348,18193044,20562859,20966902,22248718,25378659,25490467,26186194	15		NP_116241.2|MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYSDDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGERTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKMLKFSSKEKYPLFTFVNGHSRDYDFTSTTTNEEDLFSEDEKKQLKRFSTEEFVLL,NP_835739.1|MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYSDDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGERTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKMLKFSSKEKYPLFTFVNGHSRDYDFTSTTTNEEDLFSEDEKKQLKRFSTEEFVLL,XP_005271345.1|MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYSDDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGERTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKMLKFSSKEKYPLFTFVNGHSRDYDFTSTTTNEEDLFSEDEKKQLKRFSTEEFVLL,XP_011540615.1|MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYSDDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGERTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKNQIMIKAAIINIHVQDFMWT,XP_011540616.1|MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYSDDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGITIYVAQDCTGYFKPGILCGYYWWQT
4	ATG4D	84971		ATG4D	APG4-D|APG4D|AUTL4	human	NM_001281504.1,NM_032885.5,NR_104024.1,NR_104025.1,XM_006722927.1	NP_001268433.1,NP_116274.3,XP_006722990.1	NC_000019.10,NC_018930.2,NT_011295.12,NW_004929414.1	B4DGM8,Q86TL0	Cysteine protease ATG4D, mitochondrial.	NULL				Hs.512799	8125298,8889548,12446702,12477932,14702039,15489334,17207965,19549685,22441018,23508006,25490467	15		NP_001268433.1|MQVLHLAGRCPYVSPGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL,NP_116274.3|MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPDEVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL,XP_006722990.1|MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPDEVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRVYKADVARLVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL
4	Atg4a	666468		Atg4a	AI627006|AV169859|Apg4a|Atg4al|Autl2	mouse	NM_174875.3	NP_777364.3	AC_000042.1,NC_000086.7,NT_039716.8,NT_039718.8,NW_001035180.1,NW_001035183.1	Q5EBK1,Q8C9S8	Cytoplasm.	NULL				Mm.102230,Mm.393320	10349636,11042159,11076861,11217851,12446702,12466851,12477932,16141072,16141073,16602821,21267068,25652854	19		NP_777364.3|MESVMSKYENQILIFPDYLEEFPDTDELVWILGKQHPLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVIKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADPAGDFLTASNQSRDTSVPCSAWKPLLLIVPLRLGINQINPVYVEAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDIEESGLVDDQTFHCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIESTEQLEDFELEEDFEILSVG
4	Atg4b	66615		Atg4b	2510009N07Rik|AW048066|Apg4b|Atg4bl|Autl1	mouse	NM_174874.3,XM_006529793.1	NP_777363.1,XP_006529856.1	AC_000023.1,NC_000067.6,NT_078297.7,NW_001030662.1	A0A0R4J065,Q8BGE6	Cytoplasm.	NULL				Mm.29087	8889548,10349636,10725249,10922068,11042159,11076861,11217851,12446702,12466851,12477932,12904583,14530254,14610273,14621295,15489334,15782199,16141072,16141073,16602821,18083104,18768752,18799693,20577052,20634410,21267068,21701497,22025678,22055344,23093945,23585228,23754749,23861892,25578879,25906080,25916556,26235979,26378241	19		NP_777363.1|MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRRNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL,XP_006529856.1|MLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFNVLNAFLDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRANLPCVGAAALPTDSERHCNGFPAGAEVTNRPSAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVELTDSCFIPDESFHCQHPPSRMGIGELDPSIAVGFFCKTEEDFNDWCQQVKKLSQLGGALPMFELVEQQPSHLACQDVLNLSLDSSDVERLERFFDSEDEDFEILSL
4	Atg4c	242557		Atg4c	Apg4-C|Apg4c|Atg4cl|Autl1	mouse	NM_001145967.1,NM_175029.3,XM_006503071.2,XM_006503072.2,XM_006503073.2,XR_376316.2,XR_867860.1,XR_867862.1,XR_867863.1,XR_867864.1,XR_867865.1,XR_867	NP_001139439.1,NP_778194.3,XP_006503134.1,XP_006503135.1,XP_006503136.1	AC_000026.1,NC_000070.6,NT_039264.7,NW_001030747.1	Q3UYA5,Q811C2	Cytoplasm.	NULL				Mm.241663	8889548,10349636,10922068,11042159,11076861,11217851,12446702,12466851,12477932,14610273,15489334,16141072,16141073,16602821,17442669,18806760,21267068,21677750,22753949	19		NP_001139439.1|MEASGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDESKMLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEASALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKMLKISSKEKYPLFTFVNGHSKDFDFTSTAASEEDLFSEDERKNFKRFSTEEFVLL,NP_778194.3|MEASGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDESKMLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEASALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKMLKISSKEKYPLFTFVNGHSKDFDFTSTAASEEDLFSEDERKNFKRFSTEEFVLL,XP_006503134.1|MEASGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEGNVEEFRKDFISRIWLTYREEFPQIEASALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKMLKISSKEKYPLFTFVNGHSKDFDFTSTAASEEDLFSEDERKNFKRFSTEEFVLL,XP_006503135.1|MEASGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDESKMLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEASALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKTFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFERASEEITKMLKISSKEKYPLFTFVNGHSKDFDFTSTAASEEDLFSEDERKNFKRFSTEEFVLL,XP_006503136.1|MEASGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDESKMLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEASALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALHIENADSDSWTSNTVKKFTASFEASLSGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGDWYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPVRLGGERTNTDYLEFVKMLKISSKEKYPLFTFVNGHSKDFDFTSTAASEEDLFSEDERKNFKRFSTEEFVLL
4	Atg4d	235040	Cysteine protease ATG4D, mitochondrial	Atg4d	9830134P12Rik|APG4-D|Apg4d|Atg4dl|Autl4	mouse	NM_153583.10,XM_006510185.1	NP_705811.8,XP_006510248.1	AC_000031.1,NC_000075.6,NT_039472.8,NW_001030907.1	Q8BGV9	Cysteine protease ATG4D, mitochondrial.	NULL			Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability (By similarity). {ECO:0000250}.	Mm.440165	8889548,10349636,11042159,11076861,11217851,12446702,12466851,12477932,14610273,15489334,15782199,16141072,16141073,16602821,18799693,21267068	19		NP_705811.8|MNSVSPAAAQYRSGSSEDARRADCRRPRGQTRIPDPSNLGPSGSGVAALGSSGTDPAEPDEVDKFKAKFLTAWNNVKYGWAVKSRTSFSKISTVHLCGRCYHFEGEGDIQRFQRDFVSRLWLTYRRDFPPLAGGSLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWRWVEGTGLASSEMPGPASPSRCRGPGRRGPPRWTQGALEMEQDRWHRRIVSWFADHPRAPFGLHRLVELGRSSGKKAGDWYGPSVVAHILRKAVESCSEVSRLVVYVSQDCTVYKADVARLLSWPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRSELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQPSFPLESFHCTSPRKMAFAKMDPSCTVGFYAGNRKEFETLCSELMRILSSSSVTERYPMFTVAEGHAQDHSLDALCTQLSQPTLRLPCTGRLLKAKRPSSEDFVFL,XP_006510248.1|MLRSGQMMLAQGLLLHFLPRDWRWVEGTGLASSEMPGPASPSRCRGPGRRGPPRWTQGALEMEQDRWHRRIVSWFADHPRAPFGLHRLVELGRSSGKKAGDWYGPSVVAHILRKAVESCSEVSRLVVYVSQDCTVYKADVARLLSWPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRSELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQPSFPLESFHCTSPRKMAFAKMDPSCTVGFYAGNRKEFETLCSELMRILSSSSVTERYPMFTVAEGHAQDHSLDALCTQLSQPTLRLPCTGRLLKAKRPSSEDFVFL
4	ATG4	855498	Cysteine protease ATG4		APG4|AUT2	baker's yeast	NM_001183061.1	NP_014176.2	NC_001146.8	P53867	Cytoplasm. Nucleus.	NULL			Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine. ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. Moreover not only conjugation, but also subsequent ATG8-PE deconjugation performed also by ATG4 is an important step required to delipidate ATG8 to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components. ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS. {ECO:0000269|PubMed:11038174, ECO:0000269|PubMed:11100732, ECO:0000269|PubMed:11149920, ECO:0000269|PubMed:11904149, ECO:0000269|PubMed:16680092, ECO:0000269|PubMed:17632063, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:22240591, ECO:0000269|PubMed:22652539, ECO:0000269|PubMed:8050581, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:9649430}.		8849441,9169873,9649430,11038174,11149920,11805837,17632063,18701704,18719252,18971623,19398890,19793921,19840948,20093466,21987634,22240591,22768199,22782902,24470217,24586198,25483965,26061644	28	1->73,401->418,474->494	NP_014176.2|MQRWLQLWKMDLVQKVSHGVFEGSSEEPAALMNHDYIVLGEVYPERDEESGAEQCEQDCRYRGEAVSDGFLSSLFGREISSYTKEFLLDVQSRVNFTYRTRFVPIARAPDGPSPLSLNLLVRTNPISTIEDYIANPDCFNTDIGWGCMIRTGQSLLGNALQILHLGRDFRVNGNESLERESKFVNWFNDTPEAPFSLHNFVSAGTELSDKRPGEWFGPAATARSIQSLIYGFPECGIDDCIVSVSSGDIYENEVEKVFAENPNSRILFLLGVKLGINAVNESYRESICGILSSTQSVGIAGGRPSSSLYFFGYQGNEFLHFDPHIPQPAVEDSFVESCHTSKFGKLQLSEMDPSMLIGILIKGEKDWQQWKLEVAESAIINVLAKRMDDFDVSCSMDDVESVSSNSMKKDASNNENLGVLEGDYVDIGAIFPHTTNTEDVDEYDCFQDIHCKKQKIVVMGNTHTVNANLTDYEVEGVLVEKETVGIHSPIDEKC
4	apg4	9625150				volvox	XM_002948262.1	XP_002948308.1	NW_003307552.1	D8TP78	Cytoplasm.	NULL					20616280	81		XP_002948308.1|MELLMAGLLKSSFWIQRSISRVGVIELSSYVLCGAPLRDGIAQQLGPAPDTGGVSLPAAGVLDGDDYDRRSCNHSSQTGSSGTDTSTDRDSRSRQQVPEELSGEMAPGQRVAKVTHGLPVNAVTELKKGSAEGSTGCDGPDISPARRSGSACGSREAPRTSGGNRARDSAFGAAGCRGAGAQGYQHGLCGGDVAAGPSGRPAASAPLLLLIPLTLGMDKINPVYLPQLQRILTWPQSVGIVGGRPSASLYLCGVQDSSFLFLDPHEAQPTVRWGIAGDAGHTKEAGNGGSAVVLPASSLATYFCDTVRLMPATALDPSMAIGFLCMGAADLEDLFTRLDALAKEHSLAPLMTLTSGTAQAGVGLEDDFGEPEVGGAQHGGQQQQLEEWELV
5	atg-5	171735				nematode	NM_001306511.1,NM_058484.5,NM_182058.4	NP_001293440.1,NP_490885.3,NP_871858.2	NC_003279.8	Q3V5I7,Q3V5I8,W6RR39	Preautophagosomal structure membrane.	NULL				Cel.16294	9851916,17901876,19705512	5		NP_001293440.1|MDYEVCRKVWESHVPCQFTLQSSGGTHGEPLPFYTMLPRFSYLALAIQKVLSSFNRRDDGEKVHSDKMWLEHNGIPLKMYIPIGVIYDQANLSENDSILEIIVRTSQPPPQFQMVDRDMMEAMFMQNIKEADYLKTKAEITKNMMKDESAQLWRSVCNNNFDEFWTIVQKLMETSEGNEFAHIPLRVYVKNQAFKQALITAKHPDGSLRTIGEAVSDVLSSSSSSSTDSQSEHPPRLISHGIDIPHHTPLIFAAKNLSYPDNFIHVVLLLVVP,NP_490885.3|MDYEVCRKVWESHVPCQFTLQSSGGTHGEPLPFYTMLPRFSYLALAIQKVLSSFNRRDDGEKVHSDKMWLEHNGIPLKMYIPIGVIYDQANLSENDSILEIIVRTSQPPPQFQMVDRDMMEAMFMQNIKEADYLKTKAEITKNMMKDESAQLWRSVCNIPDNFDEFWTIVQKLMETSEGNEFAHIPLRVYVKNQAFKQALITAKHPDGSLRTIGEAVSDVLSSSSSSSTDSQSEHPPRLISHGIDIPHHTPLIFAAKNLSYPDNFIHVVLLLVVP,NP_871858.2|MDYEVCRKVWESHVPCQFTLQSSGGTHGEPLPFYTMLPRFSYLALAIQKVLSSFNRRDDGEKVHSDKMWLEHNGIPLKMYIPIGVIYDQANLSENDSILEIIVRTSQPPPQFQMVDRDMMEAMFMQNIKEADYLKTKAEITKNMMKDESAQLWRSVCNSMGVF
5	ATG5	9474		ATG5	APG5|APG5-LIKE|APG5L|ASP|hAPG5	human	NM_001286106.1,NM_001286107.1,NM_001286108.1,NM_001286111.1,NM_004849.3,NR_104402.1,NR_104403.1,XM_011536263.1	NP_001273035.1,NP_001273036.1,NP_001273037.1,NP_001273040.1,NP_004840.1,XP_011534565.1	NC_000006.12,NC_018917.2,NT_025741.16,NW_004929328.1	A9UGY9,Q7Z3H3,Q9H1Y0	Cytoplasm.  Preautophagosomal structuremembrane.	NULL				Hs.486063	7796880,9563500,9852036,10702672,11096062,11266458,11349150,11725643,11825910,12207896,12417306,12477932,12482611,12665549,12703993,12890687,14574404,14702039,15292400,15342556,15489334,15778222,16341674,16998475,17207965,17353931,18296641,18353420,18448665,19066443,19124466,19148225,19194464,19197948,19273585,19322201,19375507,19783847,19838193,19881538,19901552,20038797,20190558,20379614,20417604,20529838,20562859,20580051,20639872,20697744,20962850,21068098,21241894,21575909,21622776,21655094,21664058,21722286,21795849,21976705,21995634,22040493,22052905,22170153,22342342,22536318,22863883,22982048,22993366,23075929,23093945,23202584,23235332,23242420,23262492,23273568,23317196,23322078,23384565,23429496,23486359,23740937,23945651,23997112,24027027,24186333,24205307,24269628,24300435,24324106,24390342,24582693,24727585,24739953,24953774,24954904,25032862,25329677,25416956,25439980,25481044,25484072,25787994,26039132,26186194,26282792,26344197,26673895,26747760	15		NP_001273035.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD,NP_001273036.1|MHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD,NP_001273037.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDLTSFGPSIGNSWNILQKKMDFVISPLEYIRQRLKDLSFRSCFVLWLQMDSCTH,NP_001273040.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYTDLTSFGPSIGNSWNILQKKMDFVISPLEYIRQRLKDLSFRSCFVLWLQMDSCTH,NP_004840.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD,XP_011534565.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQVTAVWVGIQRFQASEEESEDEEFLATLTGGERSGKARKQWTQ
5	Atg5	11793	Autophagy protein 5	Atg5	2010107M05Rik|3110067M24Rik|AW319544|Apg5l|Atg5l|C88337|Paddy	mouse	NM_001314013.1,NM_053069.6,XM_011243108.1	NP_001300942.1,NP_444299.1,XP_011241410.1	AC_000032.1,NC_000076.6,NT_039492.8,NW_001030413.1	Q99J83	Cytoplasm. Preautophagosomal structure membrane.	NULL			May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma- induced autophagic cell death by interacting with FADD (By similarity). {ECO:0000250}.	Mm.22264	8889548,9563500,9626506,10349636,10725249,10922068,11042159,11076861,11217851,11266458,11707774,11890701,12466851,12477932,12482611,12520002,12665549,14610273,15292400,15489334,15525940,15680329,15782199,16141072,16141073,16300732,16602821,16625204,16794605,16885219,17190837,17350577,17450150,17510285,17700057,17709747,17912025,18054316,18097414,18188005,18196969,18268032,18281291,18341993,18443221,18448665,18452703,18502787,18551130,18591426,18599786,18701890,18782848,18799693,18849966,18946037,18996346,19066443,19139628,19167256,19174008,19246181,19250911,19270696,19276668,19299702,19339967,19433452,19463158,19466606,19571141,19647221,19783656,19783847,19794493,19812211,19844159,19881538,19920074,19956591,20062534,20147545,20159618,20171125,20200449,20206555,20417604,20421418,20453062,20519119,20577052,20600704,20723759,21041446,21119005,21220506,21241894,21267068,21368103,21378313,21421825,21493778,21498569,21551061,21641547,21681844,21690395,21701497,21746920,21795849,21807906,21909099,21957292,22055344,22068051,22082872,22240590,22265049,22302984,22362782,22440612,22445600,22491424,22496425,22508836,22520467,22649237,22684107,22710871,22749352,22764087,22842577,22847423,22850627,22901810,22917578,22982048,23052835,23093667,23093945,23123158,23184977,23195496,23211599,23274085,23327930,23354484,23382543,23426372,23455425,23479732,23521856,23633952,23704209,23800883,23831471,23863932,23870125,23878245,23884556,23907538,23918802,23921551,23939249,23954414,24035364,24089205,24089209,24121838,24185898,24209762,24211573,24240988,24268578,24275661,24290752,24305049,24310610,24315994,24376899,24418158,24441423,24445999,24466199,24550300,24591649,24668739,24802098,24875860,24895007,25075440,25109817,25179110,25216585,25227738,25305080,25316028,25341032,25398946,25406339,25437438,25497209,25585051,25683712,25695667,25708836,25788702,25894570,25936644,25959047,26040720,26235979,26320416,26387641,26416964,26502054,26649827	19		NP_001300942.1|MSFPEKDLLHCPSKDAVEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKRSQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIVPQPTD,NP_444299.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDVSEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAVEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKRSQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIVPQPTD,XP_011241410.1|MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDVSEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAVEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKRSQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIVPQPTD
5	ATG5	855954	Autophagy protein 5		APG5	baker's yeast	NM_001183963.1	NP_015176.1	NC_001148.4	Q12380	Preautophagosomal structure membrane.	NULL			Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E2 activity. Plays a role in the regulation of filamentous growth and chronological longevity. {ECO:0000269|PubMed:10406794, ECO:0000269|PubMed:10712513, ECO:0000269|PubMed:11149920, ECO:0000269|PubMed:15247238, ECO:0000269|PubMed:15947785, ECO:0000269|PubMed:16874032, ECO:0000269|PubMed:17890363, ECO:0000269|PubMed:17986448, ECO:0000269|PubMed:18625846, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:23064152, ECO:0000269|PubMed:23503366, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:8921905, ECO:0000269|PubMed:9759731}.		8849441,8921905,9169875,9759731,10406794,10688190,10712513,11139573,11149920,11283351,11689437,11805837,11897782,15155809,15947785,16040659,16874032,17012802,17167106,17192262,17986448,18497569,18627629,18701704,18719252,19793921,19840948,19889643,20093466,20489023,21987634,22240591,22768199,22889849,23064152,23078654,23238393,23503366,23549786,24586198,25461810,26061644,26673895	28		NP_015176.1|MNDIKQLLWNGELNVLVSIDPSFLMKGSPREIAVLRIRVPRETYLVNYMPLIWNKIKSFLSFDPLTDSEKYFWFEHNKTPIPWNYPVGVLFDCLAGKSATFTTSFENQVKDVLTFLRIHLVMGDSLPPTIIPIASSKTQAEKFWFHQWKQVCFILNGSSKAIMSLSVNEARKFWGSVITRNFQDFIEISNKISSSRPRHIPLIIQTSRTSGTFRISQPTISMTGVNPTLKDIEGDILDVKEGINGNDVMVICQGIEIPWHMLLYDLYSKLRSFDGFLYITLVPIKGGDKASSEL
6	BECN1	8678		BECN1	ATG6|VPS30|beclin1	human	NM_001313998.1,NM_001313999.1,NM_001314000.1,NM_003766.4,XM_005257758.2,XM_005257759.2,XM_005257760.2,XM_011525421.1	NP_001300927.1,NP_001300928.1,NP_001300929.1,NP_003757.1,XP_005257815.1,XP_005257816.1,XP_005257817.1,XP_011523723.1	NC_000017.11,NC_018928.2,NT_010783.16,NW_004929407.1	A0A024R1X5,B4DQ36,E7EV84,Q14457,W0FFG4	NULL	NULL		23192,11140,10146,11345,5562,5565,5571,9821,9100		Hs.716464	7490091,7829101,8125298,9765397,10395800,10604474,11306555,11309306,11564866,12372286,12477932,14966907,14970205,15489334,15922724,16179260,16267277,16390869,16417406,16522639,16713569,16718815,16857678,16874027,17203225,17236580,17272502,17337444,17355787,17438366,17441324,17441338,17446862,17550384,17589504,17595761,17643073,17659302,17724469,17786023,17999086,18005679,18184403,18184459,18497881,18497889,18552835,18628207,18641390,18769161,18797192,18829541,18843052,19049976,19050071,19060920,19066461,19130303,19145109,19180116,19218137,19270693,19270696,19273585,19289499,19298526,19298604,19318089,19325567,19347031,19372752,19375507,19395874,19520853,19535901,19535919,19556884,19635843,19641499,19680556,19713971,19762066,19778902,19798108,19921231,19959994,20004946,20009549,20010695,20023428,20037818,20090905,20150769,20190558,20206246,20207475,20208530,20230646,20368806,20454448,20473282,20501938,20559548,20562859,20622903,20638385,20639699,20643123,20697744,20711182,20819940,20842118,20863706,20889974,20921139,20937944,21062745,21081164,21139567,21203962,21209283,21239722,21241894,21327823,21353614,21358617,21420796,21444671,21478185,21499230,21537144,21543763,21556768,21597469,21610315,21646862,21654208,21681342,21711108,21722286,21729531,21750416,21769915,21777947,21779982,21861179,21873141,21875280,21936852,21962518,21971985,21976705,22028648,22039439,22081109,22095667,22147978,22157765,22174682,22219388,22240664,22242123,22248718,22286270,22301112,22310240,22314358,22335943,22392728,22393062,22493499,22498477,22622204,22627130,22648564,22650021,22674982,22733132,22742832,22797916,22805532,22875631,22933281,23029344,23089287,23112296,23125008,23168911,23182941,23184933,23197835,23216071,23225331,23264393,23315026,23316280,23332761,23334926,23337876,23420005,23427159,23429496,23444126,23478334,23479509,23504944,23525201,23541952,23564079,23569248,23573264,23686476,23703612,23722017,23737459,23787295,23790316,23801739,23812859,23827971,23877263,23878393,23880165,23935917,23943370,23954414,23974797,24012002,24034250,24056301,24056303,24132590,24141421,24145555,24186333,24186908,24188325,24260370,24303007,24324106,24324270,24345332,24349490,24365867,24378767,24385262,24386307,24440703,24443581,24472739,24478461,24528868,24535641,24587252,24623173,24681041,24690321,24716949,24733562,24755562,24760274,24785657,24879156,24885292,24941712,24956373,24969889,24970676,24971696,24980959,24980960,25032846,25046113,25096824,25115400,25127057,25136588,25175672,25179078,25196438,25204229,25208472,25215947,25275521,25292086,25311841,25318890,25366815,25400807,25427639,25436332,25439234,25466963,25472497,25484083,25490155,25496667,25499913,25594178,25596085,25607466,25620738,25631043,25639875,25649430,25669656,25689150,25693418,25708267,25714112,25714272,25715028,25758178,25803737,25814554,25821789,25824726,25825496,25837021,25847297,25871810,25891078,25906440,25955014,25984893,26008601,26055714,26097572,26148234,26186194,26319552,26347139,26363527,26496610,26590968,26673895,26722036	15		NP_001300927.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK,NP_001300928.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKDGCGERQD,NP_001300929.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKDGCGERQD,NP_003757.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK,XP_005257815.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK,XP_005257816.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK,XP_005257817.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKDGCGERQD,XP_011523723.1|MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKAEVQWHDLGLLQPPPPGFKQFPCLSLLSIWDYRHAPPRPAN
6	Becn1	56208	Beclin-1-C 37 kDa {ECO:0000303|PubMed:21364619}	Becn1	4921513J16Rik|5430417M23Rik|Atg6	mouse	NM_019584.3,XM_006533784.2	NP_062530.2,XP_006533847.1	NC_000077.6,NT_096135.6,NW_001075913.1	O88597	Beclin-1-C 37 kDa.	NULL		9821	Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors (By similarity). {ECO:0000250|UniProtKB:Q14457}.	Mm.178947,Mm.288064	9610637,9765397,10349636,11042159,11076861,11217851,12372286,12466851,12477932,14610273,14638851,14657337,15131264,15782199,16004578,16141072,16141073,16522639,16602821,16874043,16969128,17332429,17350577,17468177,17510285,17540004,17589504,17606641,17607355,17786023,17786025,17891140,17940279,18281291,18451870,18497881,18497889,18570871,18621691,18772134,18806760,18843052,18948195,19015235,19049976,19176312,19270693,19270696,19520853,19654319,19864570,20421418,20498061,20501938,20819940,20935509,20947830,21139567,21151103,21217818,21239722,21367693,21368103,21444671,21464117,21479246,21543763,21611191,21660048,21677750,21681844,21685724,21737790,21746920,21911604,21926971,21972018,21976705,22144182,22157765,22240590,22258505,22294621,22302984,22351764,22371349,22393062,22440612,22493499,22558309,22592897,22742832,22751932,22753949,22843615,23011054,23115045,23184933,23195496,23197835,23308102,23332761,23341467,23364696,23380905,23569248,23589298,23611643,23650262,23658055,23685627,23737459,23793984,23798385,23825228,23894198,23971531,23974797,24012002,24056303,24141421,24177427,24200693,24324270,24386307,24458007,24550138,24771295,24849286,24879156,24905722,24988431,25086229,25246579,25275521,25350163,25366815,25472497,25483966,25484083,25561470,25586377,25714272,25837021,25915474,26209658,26235979,26590968	19		NP_062530.2|MEGSKASSSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEEANSGEEPFIETRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK,XP_006533847.1|MMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
6	atg6	3361548	Vacuolar protein sorting-associated protein atg6		SPAC3A12.01c		XM_001712999.2	XP_001713051.1	NC_003424.3	P87117	Endosome membrane.	NULL		55102,51236,3337,7266,10916,11331,8243,11152	Required for cytoplasm to vacuole transport (Cvt), autophagy, nucleophagy, and mitophagy, as a part of the autophagy- specific vps34 PI3-kinase complex I. This complex is essential to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the preautophagosomal structure. Also involved in endosome-to-Golgi retrograde transport as part of the vps34 PI3- kinase complex II (By similarity). Plays a role in meiosis and sporulation. {ECO:0000250, ECO:0000269|PubMed:19778961}.		11859360,16823372,21504829,22681890,23950735,26771498	33		XP_001713051.1|MQYLCQRCHSLINFKDVYDDDLLKLKNLPKSRFVQASSLTEMNESGESDDQMNSSSEDYPAQRLQLYKKTISEGDYNFDNVPPPELRTPTLDSFVVLPAAKDGYEEEKNSPEEVNDLFSWKIEIYNRIFDLLSSKTKVDHPLCVECAELLTEEMSKTLRALKEEKKMYFNYDNFLSSQTVHEENTAALDSEIDELMKQINEKEEKIEEISDETDKLQKLLRELDEEKEKVYAEEQEFYNNLNQFQIKKLSLERQYDCANLEFEHNSRKLEKLQKMNVFSDIFYISHYSEPNGEGSIATINGLRLGRLPSQKVNWAEINAAWGMTVLLLDVLTEKLDFHSSSYQLKPFGSQSFIIRFDRDPNGNQVKPTKLDLFSSGELKIFMNRRFDQGMVAFLDYLHQFGDFCAAKTPSAVLPYAIENDRIGGKCIRLAFNQDENWTRALKFVLTDIKFLEAYVSSQDKQSNF
6	apg6	9628399				volvox	XM_002952015.1	XP_002952061.1	NW_003307570.1	D8U0G1	NULL	NULL					20616280	81		XP_002952061.1|LASLSAAAADLDSLEERYWNDVNDLELLLRAHTEERGALLAKIDRAGQRLQLLKNTSVLYDAFKIWHDGPFGTISGFRLGRTPEVPVEWDEINAAWGQAVLLLHTMAQVMLMMIQHRLLPMGSHPRVADKRATYDLFGPVSKLWSANYDRAMVAYLACLREFGEHAKKKDLQGGKPTQFNFPFPIDGDKVNNHTIKLTLNKDVRWTKALKFMLANLKVRHHVVPRTVRQRRWRRSRGAACNLGHPQQLGRQSSFTG
7	ATG7	10533		ATG7	APG7-LIKE|APG7L|GSA7	human	NM_001136031.2,NM_001144912.1,NM_006395.2,XM_006712931.2,XM_006712932.2,XM_006712933.2,XM_011533277.1,XM_011533278.1,XM_011533279.1,XM_011533280.1,XM_	NP_001129503.2,NP_001138384.1,NP_006386.1,XP_006712994.1,XP_006712995.1,XP_006712996.1,XP_011531579.1,XP_011531580.1,XP_011531581.1,XP_011531582.1,XP_	NC_000003.12,NC_018914.2,NT_022517.19,NW_004929309.1	B3KQM6,O95352	Cytoplasm.  Preautophagosomalstructure.	NULL		9140,55054,23192,9474,10533,25851,11337,11345,643246,4131,23363		Hs.38032	10233149,11096062,11825910,11890701,12477932,12482611,12890687,15342556,15355958,15489334,16303743,16303767,16344560,16704426,18029348,18083104,18187620,18296641,18688877,19124466,19148225,19279012,19635843,19881538,20083906,20195357,20379614,20543840,20562859,20697744,20723759,21274862,21655094,21832049,21903422,22170151,22354037,22499945,22622204,22674379,22863883,22927446,23290079,23295909,23386620,23527187,23640897,23824909,23894380,24023838,24068947,24097068,24186333,24362031,24681637,25126726,25339774,25921289,26043688,26186194,26214133,26344197,26468292	15		NP_001129503.2|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI,NP_001138384.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFAIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKIWDMSDDETI,NP_006386.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI,XP_006712994.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEDHLSFIRPKNGTFPAHQATCTQESAACPEIDLYQLSSRTIPCIHT,XP_006712995.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEDHLSFIRPKNGTFPAHQATCTQESAACPEIDLYQLSSRTIPCIHT,XP_006712996.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEDHLSFIRPKNGTFPAHQATCTQESAACPEIDLYQLSSRTIPCIHT,XP_011531579.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEDHLSFIRPKNGTFPAHQATCTQESAACPEIDLYQLSSRTIPCIHT,XP_011531580.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEDHLSFIRPKNGTFPAHQATCTQESAACPEIDLYQLSSRTIPCIHT,XP_011531581.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAELHQEPLMTNMPLEASRSCGKPPCQHSDLFPMERNRSGD,XP_011531582.1|MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGTALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEALECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQYPGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQVLDQYEREGFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEDHLSFIRPKNGTFPAHQATCTQESAACPEIDLYQLSSRTIPCIHT,XP_|
7	Atg7	74244		Atg7	1810013K23Rik|Agp7|Apg7l|Atg7l|Gm21553	mouse	NM_001253717.1,NM_001253718.1,NM_028835.4,XM_006506707.1,XM_006506708.2,XM_006506709.1,XM_006506710.2,XM_011241493.1,XM_011241494.1,XM_011241495.1	NP_001240646.1,NP_001240647.1,NP_083111.1,XP_006506770.1,XP_006506771.1,XP_006506772.1,XP_006506773.1,XP_011239795.1,XP_011239796.1,XP_011239797.1	AC_000028.1,NC_000072.6,NT_039353.8,NW_001030811.1	A0A0A0MQN4,Q3TM87,Q9D906	Cytoplasm.  Preautophagosomalstructure.	NULL				Mm.275332	8889548,10349636,10922068,11042159,11076861,11217851,11890701,12466851,12477932,12482611,12520002,12890687,14610273,15131264,15489334,15782199,15866887,16141072,16141073,16602821,16625205,16885219,17450150,17726112,18083104,18097414,18187572,18249191,18256270,18840362,18840363,18849965,18946037,19139628,19285958,19299702,19339967,19417210,19794493,19855132,19881538,19910529,19926846,19945408,20080761,20173742,20439739,20519119,20530580,20577052,20723759,20861693,21041446,21059894,21099263,21156154,21185264,21191072,21217818,21307249,21317241,21339326,21402742,21482715,21498569,21677750,21803288,21885532,21969579,21998456,22055190,22055344,22075916,22170151,22240590,22249165,22285542,22291845,22302984,22334718,22345170,22452982,22475450,22493260,22496425,22499945,22508836,22542182,22546555,22649237,22854643,22872865,22889762,22998728,23052835,23095749,23136410,23152632,23201261,23202295,23219390,23340736,23341467,23380905,23455503,23519075,23630012,23669018,23704209,23824538,23850690,23863932,23907538,23965987,23981124,24011591,24035364,24036476,24056303,24089209,24089213,24095740,24098148,24105478,24141421,24178293,24185898,24191030,24240988,24266345,24305049,24310610,24312373,24315368,24315370,24317201,24550300,24563254,24591649,24606906,24680677,24747745,24802098,24853953,24865278,24875857,24895007,24911523,24927592,24993132,25029098,25036705,25036706,25036708,25049227,25077962,25155956,25241190,25290687,25327288,25332431,25383539,25385531,25406339,25411424,25433221,25440060,25461254,25512546,25535282,25576084,25576626,25590799,25591498,25609235,25673642,25700544,25788702,25858075,25911758,25915474,26022442,26150392,26209658,26214133,26468292,26512112,26595272,26883359	19		NP_001240646.1|MHTGLWKIPTSTVVRPTPHCFPAMRLSSSGCEHLTVRLVRTVAMGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,NP_001240647.1|MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,NP_083111.1|MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_006506770.1|MHTGLWKIPTSTVVRPTPHCFPAMRLSSSGCEHLTVRLVRTVAMGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_006506771.1|MQGGWGQEIRLVRTVAMGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_006506772.1|MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_006506773.1|MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_011239795.1|MHTGLWKIPTSTVVRPTPHCFPAMRLSSSGCEHLTVRLVRTVAMGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_011239796.1|MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV,XP_011239797.1|MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV
7	ATG7	856576	Ubiquitin-like modifier-activating enzyme ATG7		APG11|APG7|CVT2	baker's yeast	NM_001179302.1	NP_012041.1	NC_001140.6	P38862	Cytoplasm.  Preautophagosomal structure.	NULL		301,11337,23710,11345,3851,727737	E1-like activating enzyme involved in the 2 ubiquitin- like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Plays a role in the regulation of filamentous growth and chronological longevity. {ECO:0000269|PubMed:10233148, ECO:0000269|PubMed:10233150, ECO:0000269|PubMed:11100732, ECO:0000269|PubMed:11149920, ECO:0000269|PubMed:12965207, ECO:0000269|PubMed:15277523, ECO:0000269|PubMed:16027116, ECO:0000269|PubMed:17632063, ECO:0000269|PubMed:17890363, ECO:0000269|PubMed:18544538, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:19061865, ECO:0000269|PubMed:19302372, ECO:0000269|PubMed:22055191, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:22785534, ECO:0000269|PubMed:23660403, ECO:0000269|PubMed:7593182, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:9759731}.		8091229,8849441,10233148,10233150,10508157,10688190,11038174,11100732,11139573,11283351,11489916,11805837,12965207,14576278,15277523,16823961,17167106,17227760,17986448,18497569,18701704,18719252,19398890,19793921,20093466,21193819,21228276,21572441,21987634,22055191,22056771,22243599,22325599,22768199,22993095,23142976,23332755,23382696,24239358,24386330,24586198,24606900,25042851,25519895,26061644,26493364	28	1->12,64->94,153->162,254->297,624->630	NP_012041.1|MSSERVLSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLTNRSFEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALECWEDGIKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPSLKGLFSKCQKWFDVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVPDLIDFKLLIIRQNEGSFALNATFASIDPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSSKQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQTKYSGSETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEISGLSVIKQEVERLGNDVFEWEDDESDEIA
7	apg7	9615836				volvox	XM_002951707.1	XP_002951753.1	NW_003307568.1	D8TZ27	NULL	NULL		5591,5700,5701,5704,5705,5708,8243,10558,8237			20616280	81		XP_002951753.1|SPSQSVVDVTFLSELSEFKLNVWKLSEDPVEIVGEQRQGSKSLKSARLPFLDTTAQLRSLSPCPDCHAAPGQLLLFNTIEGFRGSDKQSLMRQVSGQIWSDILCGAAEAEPWRLCRFLLLMHGDLKHYKFHYWFAFPALKPPAPFTLAAPPAPLASALPPTAIELVRRYSSTAHATTPPPTRCVLLSSAELPLLHACPGDGAGGGESPKRRHVVLVFSDGSHQAEYPGWQLRNVLLMAAVRWRVRELRVLCLRESSRGGGRLDPQRTVILDVRLPDIDTRSWPPPPPPPAAAAVGWEANAQGKLLPRFLDLGPHMRPEAQAEQAVDLNLRLMRWRAVPELEVGTMATTKCLLLGAGTLGCAVARTLQGWGVRHITLVDSGRVAFSNPVRQSLFNFEDCLGGGRPKAEAAAEALCRIFPSAVTRGVQLSIPMPGHPPADPAEEQALQQATQQLDDLVSEHDAVFLLTDTRESRWLPALLAAARRRIAITAAVGFDSFLVMRHGAPPGAANAPAASAGGQRRLGCYFCNDVFAPANSTRDRSLDQQCTVARPGLAPVAGALAVELLAALVQRGYAGEAALCAPPPSLAGMQPDASAPLGPAAHMVRGQLSAFSQVLMEGWAFGQCTACSAAVVEAYLARGWGLVREALQSPAALEALTGLSELHAAAAAAMMEEEEVEEEDEEAGEEEGKEERERGEGKGREVGGEEAKRGEGKEEEDEDDWTEL
7	apg8	9617238				volvox	XM_002952043.1	XP_002952089.1	NW_003307570.1	D8U058	NULL	NULL				Vca.4328	20616280	81		XP_002952089.1|MVNTRPLTFKQEHSIDKRKAEAARIKEKYPDRIPVIVEKAERSDIPDIDKKKYLVPSDLTVGQFVYVIRKRIKLSPEKAIFIFVKNVLPPTAALMSSIYEDHKDEDGFLYITYSGENTFGGVAALGEGEEQEGNEQLLLQG
8	GABARAP	11337	Gamma-aminobutyric acid receptor-associated protein	GABARAP	ATG8A|GABARAP-a|MM46	human	NM_007278.1	NP_009209.1	NC_000017.11,NC_018928.2,NT_010718.17,NW_004929405.1	O95166,Q6IAW1	NULL	NULL		9140,55054,25851,7086	Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000269|PubMed:15977068}.	Hs.647421	9892355,10856287,10899939,10900017,10931946,10984509,11042152,11096062,11146101,11414770,11461150,11727985,11727986,11729197,11779480,11825910,11875056,11885988,11890701,11948245,11979730,11997026,12367594,12477932,12507496,14625090,15169837,15695379,15977068,16169070,16303767,16339017,16874098,17164261,17353931,17580304,17581966,18638487,18976975,19056683,19154346,19250911,19363302,19533740,20010802,20111057,20200478,20452972,20562859,20639871,20665069,20706999,20810658,20820800,21376781,21383079,21617041,21684337,22267086,22354992,22421968,22470510,22939629,22948227,23043107,23209807,23545901,23602568,23721406,24089205,24100292,24198379,24240096,24582747,24668264,24686084,24879152,25126726,25126728,25127057,25215947,25224329,25498145,25684205,25771791,25847297,26040720,26186194,26347139,26413874,26687599	15		NP_009209.1|MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
8	GABARAPL1	23710		GABARAPL1	APG8-LIKE|APG8L|ATG8|ATG8B|ATG8L|GEC1	human	NM_031412.2,XM_005253344.3	NP_113600.1,XP_005253401.1	NC_000012.12,NC_018923.2,NT_009714.18,NW_004929383.1	A0A024RAP5,Q9H0R8	Cytoplasm, cytoskeleton.  Cytoplasmic vesiclemembrane.	NULL		10939,80183,9666,55626,2935,9711,22863,29982,5289,30849,5591,53635,81929,10999,8243,9126,51256,7159,80305,7248,7405,11130		Hs.524250	8495796,9892355,11076863,11230166,11256614,11374880,11414770,12477932,14625090,14702039,15292400,15489334,15489336,15604093,16189514,16381901,16431922,16704426,17580304,18296641,18541383,19001416,19250911,19549685,20010802,20197771,20200478,20562859,20628624,20810658,21516116,21597319,21617041,21620860,21691068,21893048,22120110,22354992,22470510,22658674,22948227,22959883,23043107,23602568,23721406,24647565,24668264,24747438,24879149,25127057,25416956,25684205,25771791,26040720,26050226,26186194,26347139,26451915,26673895	15		NP_113600.1|MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK,XP_005253401.1|MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLDALITHLRSGAEGVIYPDPLTYGSVRL
8	GABARAPL2	11345	Gamma-aminobutyric acid receptor-associated protein-like 2	GABARAPL2	ATG8|ATG8C|GATE-16|GATE16|GEF-2|GEF2	human	NM_007285.6	NP_009216.1	NC_000016.10,NC_018927.2,NT_010498.16,NW_004929402.1	P60520	Golgi apparatus.  Cytoplasmicvesicle, autophagosome.	NULL		64422,11337,23710,11345,440738	Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000250, ECO:0000269|PubMed:20418806, ECO:0000269|PubMed:23209295}.	Hs.461379	10747018,11076863,11096062,11146101,11256614,11414770,11825910,11890701,12473658,12477932,12507496,12581858,15169837,15489334,15489336,15604093,16169070,16189514,16303767,16381901,17353931,17580304,18187620,18768753,18776740,19056683,19250911,19322201,19533740,19549685,19635843,19844255,20010802,20010805,20029029,20200478,20468064,20562859,21177865,21383079,21460636,21497758,21516116,21617041,21669198,21684337,21832049,21900206,21988832,22354992,22421968,22470510,22885598,22959883,23043107,23112293,23142642,23891751,24089205,24269818,24550385,24582747,24668264,24747438,25086665,25127057,25416956,25684205,25771791,26040720,26284781,26347139,26451915	15		NP_009216.1|MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
8	MAP1LC3A	84557	Microtubule-associated proteins 1A/1B light chain 3A	MAP1LC3A	ATG8E|LC3|LC3A|MAP1ALC3|MAP1BLC3	human	NM_032514.3,NM_181509.2,XM_011529083.1,XM_011529084.1,XM_011529085.1	NP_115903.1,NP_852610.1,XP_011527385.1,XP_011527386.1,XP_011527387.1	NC_000020.11,NC_018931.2,NT_011362.11,NW_004929418.1	Q9H492	Cytoplasm, cytoskeleton.  Endomembranesystem.	NULL		51479,64422,23192,10533,161582,2288,23048,11345,2631,8987,9817,9895,4077,135112,4734,55361,3843,8878,64786	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). {ECO:0000269|PubMed:20713600, ECO:0000269|PubMed:24290141}.	Hs.632273	2212989,2470876,7908909,8833088,8997639,11076863,11096062,11230166,11278895,11780052,12477932,12740394,15187094,15213446,15342556,15383276,15489334,15489336,15857831,16169070,16286508,16303767,16341674,16381901,16704426,17102583,17438365,17580304,17804493,18448665,18653543,18688877,18695874,19021777,19056683,19250911,19322194,19427866,19492063,19549685,19623642,19696020,19812190,19820708,19838173,20004946,20010802,20010805,20023420,20061800,20153330,20168092,20204693,20352102,20382705,20398630,20417604,20479004,20495340,20505359,20529957,20562859,20639871,20713600,20937856,21045561,21048031,21209316,21262964,21316776,21412173,21415575,21460636,21497758,21507968,21537144,21556768,21617041,21628531,21674156,21684337,21709020,21729531,21812771,21832049,21845828,21909394,21935636,21943220,21988832,22011618,22237724,22249245,22267086,22281431,22328508,22354992,22411133,22421968,22456507,22470510,22505714,22647537,22648564,22714671,22728060,22959883,22963397,22974335,23043107,23089287,23209295,23219390,23239879,23333394,23345115,23376921,23434281,23449484,23459205,23602568,23624503,23632916,23640897,23681079,23752596,23787295,23956998,23989536,24023838,24067654,24070620,24100292,24186908,24282606,24290141,24404161,24440703,24528869,24532538,24619419,24690104,24806912,24886140,24899049,24998849,25005847,25026213,25042851,25046114,25127057,25132643,25136588,25311841,25339774,25384975,25416948,25416956,25419843,25450619,25466963,25483962,25484071,25490467,25498145,25503391,25601754,25661375,25686248,25689150,25771791,25824726,25847297,25871810,25921531,25955014,25984893,26015503,26040720,26075355,26084608,26097572,26150155,26268733,26347139,26468287,26722036	15		NP_115903.1|MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF,NP_852610.1|MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF,XP_011527385.1|MKMRFFSSPCGKAAVDPEMDLILSPRLECRAAITAHCSLELLGSSNSPVWAPQSAGITAAAAVLSASPGALEREARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF,XP_011527386.1|MKMRFFSSPCGKAAVDPEMDLILSPRLECRAAITAHCSLELLGSSNSPVWAPQSAGITAAAAVLSASPGALEREARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF,XP_011527387.1|MKMRFFSSPCGKAAVDPAAAAVLSASPGALEREARSPRSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF
8	MAP1LC3B	81631		MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	human	NM_022818.4	NP_073729.1	NC_000016.10,NC_018927.2,NG_029030.1,NT_010498.16,NW_004929402.1	Q658J6,Q9GZQ8	Cytoplasm, cytoskeleton.  Endomembranesystem.	NULL		64422,23192,10533,55717,9685,8452,161582,11337,11345,2631,8987,2997,3030,3032,89890,84078,9817,23130,3996,727737,4734,91754,8508,8439,5294,5573,5584,23637,3843,8878,23102,54958		Hs.356061	2212989,8997639,11060023,11076863,11256614,11825910,11890701,12477932,12740394,12932674,14702039,14713272,15187094,15231747,15325588,15355958,15489334,15489336,16169070,16189514,16303767,16344560,16381901,17580304,18083104,18184459,19250911,19279012,19322194,19492063,19623642,20010802,20038797,20100911,20153330,20200478,20417604,20562859,20863706,20889906,21099673,21383079,21617041,21900206,21988832,22056771,22080440,22095627,22170153,22174682,22267086,22354992,22434781,22470510,22472876,22482402,22496786,22948227,22963397,23043107,23203033,23209295,23209807,23333919,23371253,23427159,23429496,23459205,23721406,23736261,23787295,23805866,23935917,24023838,24089205,24113030,24141623,24220335,24288667,24566975,24582747,24646892,24668264,24671035,24690104,24879152,24900981,24983366,25007327,25126726,25127057,25144556,25215947,25244949,25256671,25339774,25416948,25416956,25419843,25439234,25483098,25490467,25503069,25607473,25653352,25666616,25684205,25771791,25847297,26040720,26347139,26413874,26451915,26468287,26638075	15		NP_073729.1|MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV
8	MAP1LC3C	440738	Microtubule-associated proteins 1A/1B light chain 3C	MAP1LC3C	ATG8J|LC3C	human	NM_001004343.2,XM_005273139.2	NP_001004343.1,XP_005273196.1	NC_000001.11,NC_018912.2,NT_167186.2,NW_004929294.1	Q9BXW4	Cytoplasm, cytoskeleton.  Endomembrane system.	NULL		64422,23192,10533,8452,2631,8987,3030,3032,9817,4077,4734,91754,8508,5584,51495,3843,5955,8878,54958,79876,284403	Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium. {ECO:0000269|PubMed:23022382}.	Hs.534971	2212989,8997639,12477932,12740394,15146197,15187094,15489334,16710414,19250911,20562859,22354992,22470510,23022382,23043107,23209807,23459205,24300435,24668264,25127057,25490467,25684205,25771791,25847297,26186194,26347139,26431026,26451915	15		NP_001004343.1|MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL,XP_005273196.1|MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL
8	Gabarap	56486	Gamma-aminobutyric acid receptor-associated protein	Gabarap		mouse	NM_019749.4	NP_062723.1	AC_000033.1,NC_000077.6,NT_096135.6,NT_187026.1,NW_001030480.1	Q9DCD6	Endomembrane system. Cytoplasm, cytoskeleton.  Golgi apparatus membrane.  Cytoplasmic vesicle, autophagosome.	NULL		64422,23192,10533,9685,1211,1213,79443,2631,3030,3032,9817,4130,4131,8508,8439,10015,5286,5584,22930,25782,83593,9667,8878,6788,6789,54958	Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). {ECO:0000250}.	Mm.272460	8889548,10349636,10899939,10900017,11042159,11076861,11146101,11217851,11890701,12466851,12477932,14610273,15365296,15489334,16141072,16141073,16307606,16602821,16874098,16954214,17916189,18451111,18497328,18799693,19225049,20010802,20354864,20577052,21267068,21383079,21388957,21677750,22033522,22049402,22948227,23427251,23671684,24089209,24240096,24747438	19		NP_062723.1|MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
8	Gabarapl1	57436	Gamma-aminobutyric acid receptor-associated protein-like 1	Gabarapl1	3110025G09Rik|9130422N19Rik|AI196471|Apg8l|Atg8l|GECI|MNCb-0091	mouse	NM_020590.4	NP_065615.1	AC_000028.1,NC_000072.6,NT_039353.8,NW_001030811.1	Q8R3R8	Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane.	NULL		55054,64422,23192,9474,10533,9685,1793,79443,11337,2631,3030,3032,9817,4130,4131,84557,8508,5584,83593,8878,6788,6789,54958	Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). {ECO:0000250}.	Mm.14638	8889548,10349636,11042159,11076861,11217851,11374880,11414770,12466851,12477932,14530254,15292400,15489334,15782199,16141072,16141073,16602821,16704426,17727637,18451111,20010802,20577052,21267068,21388957,21597319,21691068,22079573,22948227,23690988	19		NP_065615.1|MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
8	Gabarapl2	93739	Gamma-aminobutyric acid receptor-associated protein-like 2	Gabarapl2	0610012F20Rik|2900019O08Rik|AI173605|GATE-16|Gef2	mouse	NM_026693.5	NP_080969.2	AC_000030.1,NC_000074.6,NT_078575.7,NW_001030904.1	P60521	Golgi apparatus.  Cytoplasmicvesicle, autophagosome.	NULL		55054,64422,9474,10533,11337,11345,5289,30849,9821,10291,7024,8237	Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000250}.	Mm.371666	8889548,10349636,10747018,10900017,10922068,11042159,11076861,11217851,11414770,11890701,12466851,12477932,14610273,15489334,15782199,16141072,16141073,16602821,18799693,20577052,21383079	19		NP_080969.2|MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
8	ATG8	852200	Autophagy-related protein 8		APG8|AUT7|CVT5	baker's yeast	NM_001178318.1	NP_009475.1	NC_001134.8	P38182	NULL	NULL			Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. Moreover not only conjugation, but also subsequent ATG8-PE deconjugation is an important step required to facilitate multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of Atg9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components. Plays also a role in regulation of filamentous growth. {ECO:0000269|PubMed:10525546, ECO:0000269|PubMed:10681575, ECO:0000269|PubMed:10837468, ECO:0000269|PubMed:11038174, ECO:0000269|PubMed:11100732, ECO:0000269|PubMed:11149920, ECO:0000269|PubMed:16680092, ECO:0000269|PubMed:17132049, ECO:0000269|PubMed:17404498, ECO:0000269|PubMed:17632063, ECO:0000269|PubMed:17700056, ECO:0000269|PubMed:18508918, ECO:0000269|PubMed:19398890, ECO:0000269|PubMed:20855502, ECO:0000269|PubMed:21429936, ECO:0000269|PubMed:22622160, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:7593182, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:9649430}.		7813418,8849441,9649430,10525546,10688190,10837468,11038174,11100732,11139573,11149920,11283351,11675395,11689437,12965207,15277523,15659643,16079147,16093310,16319894,16554755,16680092,17227760,17632063,17986448,18508918,18544538,18616809,18701704,18719252,18971623,19021777,19285500,19325107,19398890,19619494,19793921,19840948,20010802,20093466,20141839,20382112,20382742,20430885,20526336,20615880,20639194,20855502,21196517,21228276,21460040,21617041,21757540,21987634,22055191,22056771,22123825,22240591,22282571,22308029,22325599,22354992,22384331,22539722,22579291,22643220,22652539,22733735,22768199,22778255,22782902,22826123,22885598,23043107,23129774,23503366,23549786,23559066,23904270,24705553,25042851,25461810,25483965,25691244,26040717,26061644,26181331,26438722	28		NP_009475.1|MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAEKSDIPEIDKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVNDTLPPTAALMSAIYQEHKDKDGFLYVTYSGENTFGR
9	ATG9A	79065		ATG9A	APG9L1|MGD3208|mATG9	human	NM_001077198.2,NM_024085.4,NR_104255.1	NP_001070666.1,NP_076990.4	NC_000002.12,NC_018913.2,NT_005403.18,NW_004929305.1	A0A024R438,Q7Z3C6	NULL	NULL				Hs.323363	11076863,11230166,12477932,14702039,15342556,15489334,15489336,15755735,16169070,16381901,16940348,17081983,19893488,19946888,20379614,20819778,21068542,21169990,21900206,21903422,22456507,23093945,24085552,24603492,24767251,24819384,25266655,25416956,25461811,25770209,26186194	15		NP_001070666.1|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEAVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSAGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAASLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPPLPRDLQGSRHRAEVASALRSFSPLQPGQAPTGRAHSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQAQAEPERHVWHRRESDESGESAPDEGGEGARAPQSIPRSASYPCAAPRPGAPETTALHGGFQRRYGGITDPGTVPRVPSHFSRLPLGGWAEDGQSASRHPEPVPEEGSEDELPPQVHKV,NP_076990.4|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEAVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSAGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAASLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPPLPRDLQGSRHRAEVASALRSFSPLQPGQAPTGRAHSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQAQAEPERHVWHRRESDESGESAPDEGGEGARAPQSIPRSASYPCAAPRPGAPETTALHGGFQRRYGGITDPGTVPRVPSHFSRLPLGGWAEDGQSASRHPEPVPEEGSEDELPPQVHKV
9	ATG9B	285973	Autophagy-related protein 9B	ATG9B	APG9L2|NOS3AS|SONE	human	NM_001317056.1,NM_173681.5,NR_073169.1,NR_133652.1,XM_011516064.1,XM_011516065.1,XM_011516066.1	NP_001303985.1,NP_775952.4,XP_011514366.1,XP_011514367.1,XP_011514368.1	NC_000007.14,NC_018918.2,NG_030317.1,NT_007933.16,NW_004929333.1	Q674R7	NULL	NULL		159,64422,23192,10533,8520,643246,4131,5931,8237,7874	Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity). {ECO:0000250}.	Hs.707300,Hs.716846	12477932,14702039,15234981,15755735,17403686,19197948,19423521,19423540,19657746,19913121,19948975,20083107,20406964,20416077,20438785,20628086,22374993,22606351,22879892,26186194	15		NP_001303985.1|MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHSALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQCPQDSPGLRVGPLIPEQDYERLEDCDPEGSQDSPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQPRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAEDGKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLLPPRDLSPTAPCPAAATASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRPCSSPSQPPSPDEEKPSWSSDGSSPASSPRQQWGTQKARNLFPGGFQVTTDTQKEPDRASCTD,NP_775952.4|MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHSALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQCPQDSPGLRVGPLIPEQDYERLEDCDPEGSQDSPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQPRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAEDGKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLLPPRDLSPTAPCPAAATASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRPCSSPSQPPSPDEEKPSWSSDGSSPASSPRQQWGTQKARNLFPGGFQVTTDTQKEPDRASCTD,XP_011514366.1|MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHSALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQCPQDSPGLRVGPLIPEQDYERLEDCDPEGSQDSPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQPRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAEDGKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLLPPRDLSPTAPCPAAATASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRPCSSPSQPPSPDEEKPSWSSDGSSPASSPRQQWGTQKARNLFPGGFQVTTDTQKEPDRASCTD,XP_011514367.1|MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHSALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQCPQDSPGLRVGPLIPEQDYERLEDCDPEGSQDSPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQPRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAEDGKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLLPPRDLSPTAPCPAAATASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRPCSSPSQPPSPDEEKPSWSSDGSSPASSPRQQWGTQKARNLFPGGFQVTTDTQKEPDRASCTD,XP_011514368.1|MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHSALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQCPQDSPGLRVGPLIPEQDYERLEDCDPEGSQDSPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQPRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAEDGKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLLPPRDLSPTAPCPAAATASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRPCSSPSQPPSPDEEKPSWSSDGSSPASSPRQQWGTQKARNLFPGGFQVTTDTQKEPDRASCTD
9	Atg9a	245860		Atg9a	AU019532|Apg9l1|Atg9|Atg9l1	mouse	NM_001003917.4,NM_001288612.1,NM_001288613.1,NR_109938.1,XM_011238687.1,XM_011238688.1,XM_011238689.1,XM_011238690.1	NP_001003917.2,NP_001275541.1,NP_001275542.1,XP_011236989.1,XP_011236990.1,XP_011236991.1,XP_011236992.1	AC_000023.1,NC_000067.6,NT_039173.8,NW_001030680.1	Q3ZAQ4,Q68FE2	NULL	NULL		55054,64422,23192,9474,10533,25851,11337,4131		Mm.238266,Mm.491221	8889548,10349636,10725249,10922068,11042159,11076861,11217851,12466851,12477932,15010206,15489334,15755735,15782199,16141072,16141073,19926846,20124090,21525242,21677750,22275429,22456507,22710871,22932492,23093945,23402761,24670807,24973144,26235979	19		NP_001003917.2|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV,NP_001275541.1|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV,NP_001275542.1|MVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV,XP_011236989.1|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV,XP_011236990.1|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQLHKQQTQAEPERHVWHRRESDESGESAPEEGGEGARAPQPIPRSASYPCATPRPGAPETTALHGGFQRRYGGITDPGTVPRGPSHFSRLPLGGWAEDGQPASRHPEPVPEEGSEDELPPQVHKV,XP_011236991.1|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGSTSSRPRLSPSGMCGTAGRVMRVERVPLKRGERVPGPPNPSPARPAIPVLHPGLEHLRPPPCMGASRGATGASQILAQCPVAPLTSPGCPWEDGQKMASQHQGTQSRCQRRAQRMNSPLKCTRYRQGGSWFPCSRMEVAAALPSLLSAMRGTL,XP_011236992.1|MAQFDTEYQRLEASYSDSPPGEEDLLVHVAEGSKSPWHHIENLDLFFSRVYNLHQKNGFTCMLIGEMFELMQFLFVVAFTTFLVSCVDYDILFANKMVNHSLHPTEPVKVTLPDAFLPAQVCSARIQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLGEVVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAVEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVRQHGHPQWLSGGQTEASVYQQAEDGKTELSLMHFAITNPGWQPPRESTAFLGFLKEQVQRDGAAAGLAQGGLLPENALFTSIQSLQSESEPLSLIANVVAGSSCRGPSLSRDLQGSRHRADVASALRSFSPLQPGAAPQGRVPSTMTGSGVDARTASSGSSVWEGQLQSLVLSEYASTEMSLHALYMHQILAQCPVAPLTSPGCPWEDGQKMASQHQGTQSRCQRRAQRMNSPLKCTRYRQGGSWFPCSRMEVAAALPSLLSAMRGTL
9	Atg9b	213948	Autophagy-related protein 9B	Atg9b	Apg912|Apg9l2|Apgdc2|Gm574|Nos3as|eONE|sONE	mouse	NM_001002897.3,XM_011249761.1	NP_001002897.2,XP_011248063.1	AC_000027.1,NC_000071.6,NT_165760.3,NW_001030784.1	Q6EBV9	NULL	NULL			Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. {ECO:0000269|PubMed:15755735}.	Mm.332252	10349636,11042159,11076861,11217851,12466851,15234981,15755735,16141072,16141073,18799693,21267068,22710871	19		NP_001002897.2|MVRRTGWGGSRRQRGRWGDLGPSSVPLLPMALPLPASPCRGTGGRRISVFSLSPAPRTRSCSSSVFPPASGSPCLVIQEAGASQTPHNVLPTPTTPSTQAHPTMIHTSASPSWGSHSTPPLASATPPPSCPRPQDHPGLRMGPLIPEQDYERLEDCDPEGSQDSPIHGEDHQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFNNQPKNHTRRGPLHSKVTLSDAILPSAQCAEKIHDSPLLVFLLVLAAGFWLFQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLELQRSGGLCVQPRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGSSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPEAYKRSDLRGVLANRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHVELLRREPGAFGARRWSRLARLQLRHFNELPHELRARLGRAYRPAAAFLRAAEPPAPLRALLARQLVFFSGALFAALLVLTIYDEDVLAVEHVLTTMTALGVTATVARSFIPEEQCQGRSSQLLLQAALAHMHYLPEEPGATGARASSYWQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSEGQTEASLSQRAEDGKTELSLMRFSLAHPQWQPPGHSSKFLGHLRGRVQQDAAAWGAPSTRSPPTPGVLSDCTSPLPEAFLANLLVNPRPPQRDLSPTAPCPAAATASLLASISRMVQDPSCVSPGGTGGQKLTQLPELVSAEMSLHAIYLHQLHQQQQQELWGEASASSPSRPWSSPSQPGSPDEEKPSWSSDGSSPASSPRQQWGTQRAQNLFPKGFQENTDTQKEPLTGPLH,XP_011248063.1|MDHPGLRMGPLIPEQDYERLEDCDPEGSQDSPIHGEDHQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFNNQPKNHTRRGPLHSKVTLSDAILPSAQCAEKIHDSPLLVFLLVLAAGFWLFQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLELQRSGGLCVQPRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGSSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPEAYKRSDLRGVLANRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHVELLRREPGAFGARRWSRLARLQLRHFNELPHELRARLGRAYRPAAAFLRAAEPPAPLRALLARQLVFFSGALFAALLVLTIYDEDVLAVEHVLTTMTALGVTATVARSFIPEEQCQGRSSQLLLQAALAHMHYLPEEPGATGARASSYWQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSEGQTEASLSQRAEDGKTELSLMRFSLAHPQWQPPGHSSKFLGHLRGRVQQDAAAWGAPSTRSPPTPGVLSDCTSPLPEAFLANLLVNPRPPQRDLSPTAPCPAAATASLLASISRMVQDPSCVSPGGTGGQKLTQLPELVSAEMSLHAIYLHQLHQQQQQELWGEASASSPSRPWSSPSQPGSPDEEKPSWSSDGSSPASSPRQQWGTQRAQNLFPKGFQENTDTQKEPLTGPLH
9	ATG9	851406	Autophagy-related protein 9 {ECO:0000303|PubMed:14536056}		APG9|AUT9|CVT6|CVT7	baker's yeast	NM_001180209.1	NP_010132.1	NC_001136.10	Q12142	Preautophagosomal structure membrane.	NULL			Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum- specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking. Anterograde trafficking requires an intact actin cytoskeleton and proper retrograde trafficking of from the PAS to the cytoplasmic vesicles requires the ATG1-ATG13 complex and the phosphatidylinositol 3-kinase complex I. Recruits ATG23 and ATG8 to the PAS. {ECO:0000269|PubMed:10662773, ECO:0000269|PubMed:10735854, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:14504273, ECO:0000269|PubMed:17132049, ECO:0000269|PubMed:17329962, ECO:0000269|PubMed:17426440, ECO:0000269|PubMed:18818209, ECO:0000269|PubMed:18829864, ECO:0000269|PubMed:22826123, ECO:0000269|PubMed:23129774, ECO:0000269|PubMed:24905091, ECO:0000269|PubMed:7593182, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:8663607}.		8849441,9169867,10662773,10688190,11382760,11805826,12192589,14504273,14723849,16093310,16319894,16429126,16787937,16874040,17135291,17178909,17204846,17329962,17426440,18287533,18497569,18701704,18829864,19182520,19337029,19371383,19793921,20065092,20083107,20093466,20489023,20861302,21887408,22282571,22384331,22768199,22826123,22977244,23129774,23409723,23549786,23904270,23986483,24165940,24440502,24586198,24881874,25385507,25557545,25817432,26181331	28	1->319,396->438,491->535,643->721,778->997	NP_010132.1|MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLPDIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLDGDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDDDTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKLPTSHRVSDIIIDKCYSNSITGFTKFFLWMFYFFVILKIVQLYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLFRTNVLTKTLEWNINLCVMGFVFNESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPKEKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTITQEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFVLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDEDSLTKKIAVNGSHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQLPAKKGYPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDNNNNGDDIKNGTNNATAKNDDNNGNNDHEYVLTESFLDSGAFPNHDVIDHNKMLNSNYNGNGILNKGGVLGLVKEYYKKSDVGR
9	VOLCADRAFT_93324	9627273				volvox	XM_002952575.1	XP_002952621.1	NW_003307574.1	D8U1U5	NULL	NULL					20616280	81		XP_002952621.1|MRLPREQEQELSNNGFHGVYTLPRYWHERGLSSILLAGALNLLALSSTAAFSTFLLLFVDWRALHAECLAPRAAGGGGGDCDLAAVALDRRPLLGRGVASDMLAVSYIAVCVVYLGWTAAHYVMDVRDMREVSHFMASKLGISEGKVVTMTWAEVVHRLVLVQRTTRLCIARDLDELHIVSRIMRKLLFPYAAVNWRHDNYLIAMINRNVLQLHLQPPADAPLAVQRVLGAVLRLFGGGGPSRGGGSAGGGGGGGGGAGCCGGRLLTKTLEWNLRWCVLDHMFDDRFRIRPEFSDVAALKRRLRAVACANVLLSPFLFMFLLAYFFMRNAERLYHHPGALGSRRWSGLAQWRIRELNELPHYLHHSSRRTRWRHLPGFWSSQRGVVAGYHDGGAGGVQVPSEGVWGGEGQEEVLSLNESLNPQCEVHAPDPQFEKAVRKTEYLACCAHKLNLGRTTDKKGNVTLVSEEPVAYDPERALADVVSYTHYLPRHWRGRAHTAEVQCAFLSMFRLKLGLFVEELASLITTPLFVSAFTTHVDGVGDVCSLALFDLARHGNAKFGAPVQAEKAFRSRQGKLEKSFLTFVATYPTWEPGEMGRRMLAALATNAGGGGGGSGAAATATTAAAAAGDSTSSDQHPLPRQAVDLLTYHPGPPTVFPYQAAAEAGKAAHVAEAAAAATALNRGVAASEFRSSSTKGVPPEEGGGGGARKGDTYSAVDASAVATAAPPPPPRMPQHDAGPRGIRRPQVPLHLQPYHGVTSYMSNTSASQLSWRPAAQSSSGAGVVPAGGSPPPSVASSQFSNLAAPYMQCYPVPLYYAQQQQLRHVQQQQYRRMYEHLMYGRPSAPLRDAVSAGGAPPPGLLPTPLSPPYHAPRMAGSSASVAGGGGAAAAAATAGWQHPSQLQLFDPSTSYSGMFHPFAFHGPHLVPLPYSPPVPALHPPPPPHPHLQHPVNQYQTRPEAHRGAASAAPSGIGGGGGGGATLAQGRVAPAAHDDDDDNPLSGGGFVELLPAVAAAPLPLPLLAPGPAVAAVASALRADPSLGFGPMEEADGFGLVPEALAPPATGGGGGGGAASSSGSSLGLMPRRWGSYGTPSRGLTERSVAPQAAATAAVLGDGGEVESPGVGGWYDRDCSYPQQQQQQQQHQPLQHIDALTAQLSALEESETVKQALTMVAYNPLARKDKKKLTGAILATDKAGRINERPFKDLDFVGHGWIGKEQKALRRENQELN
10	ATG10	83734	Ubiquitin-like-conjugating enzyme ATG10	ATG10	APG10|APG10L|pp12616	human	NM_001131028.1,NM_031482.4,XM_005248610.3,XM_005248611.3,XM_005248612.2,XM_011543660.1,XM_011543661.1	NP_001124500.1,NP_113670.1,XP_005248667.1,XP_005248668.1,XP_005248669.1,XP_011541962.1,XP_011541963.1	NC_000005.10,NC_018916.2,NT_034772.7,NW_004929322.1	Q9H0Y0	Cytoplasm.	NULL		8540,9474,10576,7203,10574,8139,6621	E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. {ECO:0000250, ECO:0000269|PubMed:21367888}.	Hs.713698	2890687,8125298,11076863,11230166,11256614,12477932,12482611,12890687,14702039,15489334,15489336,15498874,15657430,16381901,16963840,17256008,17353931,20379614,20562859,20723759,23285162,23850577,26186194	15		NP_001124500.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,NP_113670.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_005248667.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_005248668.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_005248669.1|MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_011541962.1|MCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP,XP_011541963.1|MLEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP
10	Atg10	66795		Atg10	5330424L23Rik|5430428K15Rik|AI852123|APG10|Agp10|Apg10l|Apg10p|Atg10l	mouse	NM_025770.3,XM_006517326.2,XM_006517327.2,XM_011244551.1,XM_011244552.1,XR_873450.1	NP_080046.3,XP_006517389.1,XP_006517390.1,XP_011242853.1,XP_011242854.1	AC_000035.1,NC_000079.6,NT_039589.8,NW_001030534.1	A0A0R4J029,Q8R1P4	Cytoplasm.	NULL				Mm.235385	8889548,10349636,11042159,11076861,11217851,12466851,12477932,12482611,12890687,14610273,15033168,15489334,16141072,16141073,16602821,18799693,20723759,21267068,21677750	19		NP_080046.3|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE,XP_006517389.1|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE,XP_006517390.1|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKECSDGYMCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLGTSNTWATIFCSTSLQDK,XP_011242853.1|MEDEFFGEKSFQHYCAEFIRHSQQIGDGWEWRTAKENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE,XP_011242854.1|MCKTQFRIKNETLTPHASVLTCLPTEENLELPMDDSEVTRPAAVAEVIKHEYHVLYSCSYQVPVLYFRASFLDGRPLALEDIWEGVHECYKPRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTAVLKNSQKINRNVNYITSWLSLVGPVVGLNLPLSYAKATSQSE
10	ATG10	850684	Ubiquitin-like-conjugating enzyme ATG10		APG10	baker's yeast	NM_001181862.1	NP_013058.1	NC_001144.5	Q07879	Preautophagosomal structure membrane.	NULL		10151,23130,3963,5317	E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS). Likely serves as an ATG5- recognition molecule. {ECO:0000269|PubMed:10508157, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:9759731}.		8849441,9169871,9759731,10508157,17167106,18701704,18719252,19793921,20093466,21193819,21228276,21987634,22056771,22282571,22768199,22993095,23142976,23222640,24586198,26061644	28	1->11,45->103	NP_013058.1|MIPYQEWHSQLQSLYDSQIFHNWALCQDVHLNDEKDGLLLRLIPTRQLQKNTERIENKLLNHIELYLTYSKVYNEPLLLLRIWEEKSIDGIPMTKLMLPTDIESLLDVQGKFQLGLDTIINLEGSVWYSFHPCDTSCIVGDQAEFMSTYLRRWVSIFIFSWLGYEDS
11	ATG11	856162	Autophagy-related protein 11		CVT3|CVT9	baker's yeast	NM_001184146.1	NP_015374.1	NC_001148.4	Q12527	Preautophagosomal structure membrane.	NULL		284697,3337,1785,2318,10985,10726,5214	Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for ATG9 anterograde transport from the mitochondria to the PAS. Recruits also the ATG19-prAPE1 complex to the PAS. Required for the Cvt vesicles completion. Plays a significant role in life span extension. {ECO:0000269|PubMed:10995454, ECO:0000269|PubMed:11264288, ECO:0000269|PubMed:11309418, ECO:0000269|PubMed:12479808, ECO:0000269|PubMed:15138258, ECO:0000269|PubMed:15659643, ECO:0000269|PubMed:16901900, ECO:0000269|PubMed:17012830, ECO:0000269|PubMed:17178909, ECO:0000269|PubMed:17192412, ECO:0000269|PubMed:17295840, ECO:0000269|PubMed:18077553, ECO:0000269|PubMed:18287526, ECO:0000269|PubMed:18497569, ECO:0000269|PubMed:18625846, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:18818209, ECO:0000269|PubMed:19061865, ECO:0000269|PubMed:19371383, ECO:0000269|PubMed:19619494, ECO:0000269|PubMed:19619495, ECO:0000269|PubMed:20647741, ECO:0000269|PubMed:20855505, ECO:0000269|PubMed:21343297, ECO:0000269|PubMed:21429936, ECO:0000269|PubMed:21757540, ECO:0000269|PubMed:22157017, ECO:0000269|PubMed:22308029, ECO:0000269|PubMed:22509044, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:23337777, ECO:0000269|PubMed:23559066, ECO:0000269|PubMed:8663607}.		8849441,9169875,10688190,10995454,11309418,11805837,15659643,16429126,16554755,16874092,17135291,17178909,17295840,18077553,18245329,18287526,18701704,18719252,18818209,18829864,19303850,19337029,19591838,19619494,19793921,20093466,20489023,20639194,21490424,21757540,21777812,21839922,22123825,22282571,22308029,22509044,22643220,22875988,22940862,23559066,23810512,23858448,23904270,23924895,24025448,24440502,24451165,24705553,25281559,25287303,25346786,25385507,26040717,26079297,26166702,26181331,26673895	28	1->15,106->172,224->381,483->621,667->700,848->948,1045->1098,1165->1178	NP_015374.1|MADADEYSTAPTQQEITPLQTTATIINAISGECITTNVDFFVSLDKFKQFIARKWKIPPDQLLILLPYGNKLKPSMFKELLINRSFTLNDFYVYDRRLFSLVSKPTPTNLLTSKDSNPMNSPNSNDLTETLEYLIKNSHISQYQGSDTIMIKPMPSPLEDADVDLSRLNYHSVTSLLTTNLGWLSALEIDVHYFKSLIPDIIAHIKRIFDGLTVCSQYLKLYCFDVESLYNSNVQFLNQLVDNGMTSKWEKCFNDTLSKLTALEGDSLQKFINIESLLENEKSVKILNHSINGKLNKIKREIDENASFRDIITVNIDRLRQMFTPNESKFELEDQMAESFEVLVSEMRTRSRNVLDKEEEEFNSQEFLKSMNVMLEKDKKESVKTLFTISQALYSQIGELIDLKKSLQKHAVAILGNIAFTQMEILGIKRLLLNECNKDLELYKKYEVEFAQVEDLPLIYGLYLIEKYRRLSWFQQILSFISNFNQDLELFKQNELRTRNKWVKNFGSIATVFCEDLLSSSDFKRLNEYHSHTSPPNEDEEDENENSIANYRQDLVKVSQAIDNYMTQIKETDVSEPIIDLLSKTLFETKRFHIIYSNFKNNNNNSSNGNSISPEGSIALKSDDVVKGYKTRIKKLESLLHEFQYSDIGHWPQGVLNTHLKPFRGSATSINKKKFLGASVLLEPANISEVNIDSVSQANNHQIQELESNVDDLLHQLQLLKEENNRKSMQISEMGKKISDLEVEKTAYRETLTNLNQELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKIEKLTGDYDDVSKSRERLQMDLDESNKKHEQEVNLLKADIERLGKQIVTSEKSYAETNSSSMEKGEKFETIPLAEDPGRENQISAYTQTLQDRIFDIISTNIFILENIGLLLTFDNNNNIQIRRVKGLKKGTAQSNILDESTQMLDAHDNSLIKSPVFQKLKDEYELIKSVANGSEKDTQQSIFLGNITQLYDNKLYEVAVIRRFKDIETLAKKLTKENKIKRTLLERFQREKVTLRNFQIGDLALFLPTRENVNSVGSMSSSTSSLSSSFSSVDLSTPPPLDAMSIQSSPSVIHSNVINQASISGRDKNKLMRPWAAFTAFEESTRYFLKDEKGLTKGKEWFVGRIVTLEHFVADSPSNNPFRLPKGSVWFQVTAVVVSYQGV
12	ATG12	9140	Ubiquitin-like protein ATG12	ATG12	APG12|APG12L|FBR93|HAPG12	human	NM_001277783.1,NM_004707.3,NR_033362.1,NR_033363.1,NR_073603.1,NR_073604.1	NP_001264712.1,NP_004698.3	NC_000005.10,NC_018916.2,NT_034772.7,NW_004929323.1	O94817	Cytoplasm.  Preautophagosomalstructure membrane.	NULL			Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus. {ECO:0000269|PubMed:12207896, ECO:0000269|PubMed:17709747, ECO:0000269|PubMed:17999726, ECO:0000269|PubMed:19074260, ECO:0000269|PubMed:19164948, ECO:0000269|PubMed:19666601, ECO:0000269|PubMed:23202584}.	Hs.264482	8889548,9490301,9852036,11096062,11825910,11890701,12207896,12477932,12482611,12665549,12890687,14702039,15146197,15342556,15489334,15778222,16189514,16344560,17353931,17457038,18187620,19124466,19197948,19901552,20417604,20562859,20723759,21241894,21832049,22152474,22170153,22342342,23202584,23307622,24186333,24727585,24899049,24954904,25416956,25439980,25629932,26186194,26673895	15		NP_001264712.1|MAEEPQSVLQLPTSIAAGGEGLTDVSPETTTPEPPSSAAVSPGTEEPAGDTKKKIYLCESVLCSFPRPRSWNSL,NP_004698.3|MAEEPQSVLQLPTSIAAGGEGLTDVSPETTTPEPPSSAAVSPGTEEPAGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
12	Atg12	67526	Ubiquitin-like protein ATG12	Atg12	4931423H11Rik|A330058M13Rik|Apg12l|Atg12l	mouse	NM_026217.3,XM_006526187.1	NP_080493.2,XP_006526250.1	AC_000040.1,NC_000084.6,NT_039674.8,NW_001030635.1	Q9CQY1	Cytoplasm.  Preautophagosomalstructure membrane.	NULL			Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus. {ECO:0000269|PubMed:11266458, ECO:0000269|PubMed:12890687, ECO:0000269|PubMed:20723759}.	Mm.9852	8889548,10349636,10922068,11042159,11076861,11217851,11266458,11890701,12466851,12477932,12482611,12665549,14610273,15489334,15782199,16141072,16141073,16602821,17709747,18448665,18946037,19174008,20080761,20723759,21267068,21551061,22024753,22082872,22520467,23052835,23431188,23907538,24191030,25585051,25686249	19		NP_080493.2|MSEDSEVVLQLPSAPVGAGGESLPELSPETATPEPPSSAAVSPGTEEPPGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG,XP_006526250.1|MSEDSEVVLQLPSAPVGAGGESLPELSPETATPEPPSSAAVSPGTEEPPGDTKKKIYLCESVLCPFPRPRSWNSI
12	ATG12	852518	Ubiquitin-like protein ATG12		APG12	baker's yeast	NM_001178565.1	NP_009776.1	NC_001134.8	P38316	Preautophagosomal structure membrane.	NULL			Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E2 activity. {ECO:0000269|PubMed:11149920, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:16874032, ECO:0000269|PubMed:16901900, ECO:0000269|PubMed:17295840, ECO:0000269|PubMed:17404498, ECO:0000269|PubMed:17986448, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:18725539, ECO:0000269|PubMed:18971623, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:23064152, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:9759731}.		7813418,8849441,9759731,10233150,10406794,10508157,10688190,11139573,11149920,11283351,11805837,11897782,12965207,15766533,16874032,17167106,17986448,18701704,19793921,19840948,20065092,20093466,22240591,22282571,22768199,23064152,23238393,23503366,23549786,24586198,25461810,26061644	28		NP_009776.1|MSRILESENETESDESSIISTNNGTAMERSRNNQELRSSPHTVQNRLELFSRRLSQLGLASDISVDQQVEDSSSGTYEQEETIKTNAQTSKQKSHKDEKNIQKIQIKFQPIGSIGQLKPSVCKISMSQSFAMVILFLKRRLKMDHVYCYINNSFAPSPQQNIGELWMQFKTNDELIVSYCASVAFG
13	atg-13	176150	Autophagy-related protein 13 homolog			nematode	NM_066381.4	NP_498782.1	NC_003281.10	P34379	Cytoplasm, cytosol. Preautophagosomal structure.	NULL			Autophagy factor required for autophagosome formation. {ECO:0000250}.	Cel.7923	9851916,22862955,22885670	5		NP_498782.1|MVNEYDTYNKWLKFFSVRMVQSIIQSRLGDEIESKCVPYSENAVDWFNMRIDELGEISAYLKSNIKSYPPVGTLTLEFLLYTPSGQLLPLEAWILSSSEGTDDCSRNELYHDMSTLLRSAIVSARMTPMHRLYVKKQHLETFVIMYRVFENDISSDMGKGKKTRKIGELVSKFGNISLDLHYRTSMHFEEPEIAPVTPVEDVEEEIDDGEKTVVDENIQTRTVSECVPIADAKKRKASGSVESATSAGSSTSREAAPRFILGQSTSSEDSRHSDVQNSYEEDHKPSLADLRNHSFPFVNLLQSAYNPANGTKKNSSSTCLNSPKSTPEDKEPTIEKVAESFRAAKIDEVVFEEDEDEELPLDSMELSEDSFVHFNQLSDFGGAPSLGNELGDYLKQLKTAPDMTESGDIDICNMDLKTELEKISSQTANFNNFLKHVNSFSDE
13	S6k	38654		S6k	10539|7-10|7084|CG10539|DS6K|DmelCG10539|Dp70S6k|Dp70[s6k]|Dp70s6k|Pk64F|Pk?6|S6K|S6K1|S6k|S6K|dS6K|dS6k|dp70[S6k]|dp70s6k|dps6k|ds6k|fs(3)07084|l(3)07084|p-S6K|p70 S6K|p70/S6K|p70S6K|p70[S6 kinase]|p	fruit fly	NM_001274521.1,NM_079217.3	NP_001261450.1,NP_523941.2	NT_037436.4	Q94533	NULL	NULL				Dm.856	3215511,8855259,8942996,8978055,9540809,9584098,10471706,10497130,10523207,10559955,10651243,10679387,10731132,10801327,10862736,10908587,10934032,10980431,11069885,11069888,11128988,11297505,11348591,11348592,11377964,11529271,11698190,11733057,11752451,11782950,11862217,12172554,12172555,12324955,12381661,12445406,12537568,12537572,12537573,12537574,12559758,12563289,12655636,12766775,12766776,12771962,12841848,14505573,14527345,14605208,14607085,14645523,14691557,14972680,15102439,15186745,15268862,15296710,15296714,15454083,15466161,15545626,15575970,15589139,15616552,15632201,15707896,15710747,15718470,15802506,15843412,15861189,16110336,16143107,16150727,16172603,16278294,16332201,16336044,16461276,16496002,16516475,16627617,16713952,16774996,16785324,17038544,17043309,17055976,17086199,17139322,17182864,17183368,17194782,17208179,17253963,17301792,17322403,17347671,17369395,17371599,17417628,17440611,17462592,17504806,17569856,17569867,17570358,17889654,18036784,18042644,18086911,18177722,18226226,18497260,18505882,18604198,18653470,18794330,18820430,18957936,19043547,19141596,19214204,19214224,19216764,19225150,19317915,19378453,19543366,19594484,19609361,19720874,19733656,19778508,19786572,19787055,19855819,19875983,19917724,20001959,20066047,20074526,20100334,20203043,20444422,20457147,20457610,20463884,20471266,20471268,20478529,20491566,20573703,20585550,20619819,20808898,20849947,20889130,21035763,21151574,21239477,21251254,21267071,21383842,21406223,21464442,21516106,21516128,21572965,21680868,21694719,21816278,21847093,21930778,21998598,22068330,22102829,22173880,22200592,22240900,22242005,22264732,22319582,22493059,22498699,22500638,22609549,22622177,22645656,22672579,22678283,22743648,22824239,22843669,22911822,22921367,22949833,22951642,22952930,22956542,22980980,23063786,23144631,23144943,23184942,23251396,23407678,23444356,23447678,23519314,23530222,23532117,23583758,23587196,23626835,23690177,23819996,23843608,23878397,23885240,23934892,24018644,24038661,24068890,24075010,24076014,24133012,24133450,24191061,24316039,24316411,24334257,24348428,24357229,24385933,24394412,24489769,24553922,24685228,24690889,24723892,24755363,24795642,24889782,24949430,24953188,25007267,25092766,25126791,25133314,25220459,25239948,25284370,25294944,25313405,25356674,25361581,25551675,25805973,25826530,25882208,25920570,25921541,26063572,26586826	12		NP_001261450.1|MADVSDPSELFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSILEDMHRANRMPARSPRRTPRQLPDSSFRLQFPSANVGANAPLAMHGHSQRSGMFARATPPHHMQTFAPRPSPAQDEMMDVQGLPMV,NP_523941.2|MADVSDPSELFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCINLHQDTEGQETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSILEDMHRANRMPARSPRRTPRQLPDSSFRLQFPSANVGANAPLAMHGHSQRSGMFARATPPHHMQTFAPRPSPAQDEMMDVQGLPMV
13	AKT1	207		AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	human	NM_001014431.1,NM_001014432.1,NM_005163.2,XM_005267401.1,XM_011536543.1,XM_011536544.1	NP_001014431.1,NP_001014432.1,NP_005154.2,XP_005267458.1,XP_011534845.1,XP_011534846.1	NC_000014.9,NC_018925.2,NG_012188.1,NT_026437.13,NW_004929393.1	B0LPE5,B3KVH4,P31749	Cytoplasm.  Nucleus.  Cell membrane.	NULL		8678,9711,5289,30849,5786,9392,57617,65082		Hs.525622	1533586,1718748,1851997,3037531,3384441,7774014,7891724,8524413,8940145,8978681,9005852,9019819,9312003,9368760,9373175,9381178,9394803,9395488,9512493,9736715,9768361,9812896,9829964,9973250,10082674,10085094,10102273,10217147,10224060,10226025,10358014,10358075,10376602,10376603,10377430,10438924,10454575,10485710,10485711,10490823,10490848,10491192,10497255,10527852,10542266,10570282,10576742,10617634,10635328,10698680,10748004,10833263,10866658,10869359,10869418,10872470,10896934,10910062,10926925,10930578,10958679,10983986,10995457,11035810,11042204,11116148,11139588,11154276,11154281,11156376,11156964,11208609,11274386,11278835,11313365,11313479,11404460,11410590,11410591,11425855,11438723,11445557,11500364,11504915,11508278,11509608,11535620,11546794,11579209,11583630,11585925,11598301,11689711,11696579,11707444,11707464,11710897,11715018,11723139,11756412,11777913,11782427,11809791,11825911,11828257,11839802,11855836,11877387,11884598,11902142,11903042,11923280,11956222,11960368,11976320,11994271,11994280,12009899,12011046,12042314,12062056,12062094,12070137,12077256,12112022,12124386,12138087,12138205,12145204,12149249,12150915,12167664,12167717,12176337,12176338,12176997,12194869,12218048,12244133,12244301,12244302,12244303,12297295,12376533,12393747,12438239,12446767,12446787,12458207,12477932,12524439,12527373,12529294,12535517,12586360,12592338,12621049,12637511,12722480,12727836,12734380,12741986,12750378,12757707,12768030,12782295,12783873,12791994,12808085,12808093,12853467,12874217,12888921,12919677,12952968,12972603,14499622,14500673,14505491,14520710,14523021,14534536,14560023,14566704,14568991,14611643,14612949,14623889,14625285,14636889,14645242,14645548,14647146,14657000,14679206,14702039,14713953,14742298,14749367,14749719,14755253,14761976,14970221,14973226,14985374,15001646,15010337,15016818,15026145,15047604,15047866,15060171,15067058,15102693,15115729,15118108,15136501,15146197,15149849,15156201,15173318,15183529,15187088,15187138,15194442,15203190,15217935,15224190,15231831,15242771,15262962,15262978,15263908,15271644,15283964,15284024,15316080,15326564,15331441,15342781,15342917,15385469,15388791,15389633,15459205,15465021,15467757,15470047,15475446,15489334,15492215,15522255,15525681,15527798,15533996,15539407,15545271,15545519,15546863,15572689,15574337,15580267,15581622,15607733,15609321,15616007,15665327,15665818,15668028,15678105,15688030,15689238,15705789,15710591,15718470,15722337,15723049,15743789,15753085,15778376,15784622,15800029,15802268,15806160,15808505,15809304,15817639,15818404,15831676,15833736,15837948,15840729,15843522,15845076,15845651,15856005,15861136,15879168,15888491,15896313,15896703,15905178,15910284,15911620,15922745,15961723,15982448,15987444,15993382,15994200,15998799,16007163,16007172,16007182,16009706,16012720,16019536,16026766,16027121,16027165,16027169,16036916,16044149,16049004,16049961,16055703,16076959,16091017,16098514,16099944,16107690,16114056,16115861,16123141,16128748,16139227,16141217,16142341,16148125,16160160,16163388,16174774,16177823,16186112,16202996,16210317,16216590,16224021,16243840,16256741,16263580,16272144,16274701,16278380,16280327,16282323,16293694,16338927,16343492,16354698,16362038,16365168,16373405,16395129,16405925,16407258,16407271,16412424,16417524,16428439,16434970,16453020,16466644,16474850,16478297,16508008,16524887,16525023,16532026,16532036,16537497,16540465,16543232,16549426,16551632,16564100,16568092,16571745,16583435,16601838,16603397,16604263,16613989,16616456,16644866,16651639,16670089,16682946,16684529,16723503,16732486,16763222,16774943,16775835,16780593,16785234,16790501,16790529,16792529,16797529,16814735,16818690,16820098,16820947,16822839,16836907,16839745,16840713,16841089,16842970,16844778,16849522,16862180,16897758,16912864,16916907,16926151,16932738,16946008,16951146,16962653,16972255,16977260,16981720,16982329,16982699,16987028,16987250,16988010,16990258,17006541,17006756,17008323,17012749,17015676,17016437,17024099,17030608,17041888,17043653,17050554,17052453,17060455,17065200,17068339,17081983,17088265,17097759,17098228,17099727,17113264,17124499,17128418,17136479,17136481,17141917,17143278,17148458,17151107,17157319,17169805,17173971,17179152,17210635,17214972,17215852,17233643,17235455,17244606,17274640,17276404,17287208,17287851,17299206,17300918,17307335,17310852,17317726,17317825,17318185,17318262,17333095,17335965,17342093,17349711,17351066,17360849,17375124,17383860,17386266,17386267,17400190,17404186,17406055,17428466,17443665,17458890,17461449,17462862,17468516,17469127,17470458,17471535,17478078,17483438,17493174,17495954,17495959,17501982,17504381,17505062,17507655,17507800,17510053,17512923,17513297,17513702,17520698,17521720,17522055,17522703,17533377,17535800,17544405,17544543,17546049,17549359,17551921,17553806,17554339,17565979,17566113,17569669,17577629,17580302,17581609,17584963,17594810,17599831,17599906,17601486,17606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450979,25466966,25482200,25482988,25492869,25492937,25498454,25499462,25501279,25502934,25504436,25509983,25519148,25524555,25534823,25538040,25550560,25551293,25562170,25564612,25569101,25569182,25573060,25582346,25589557,25590801,25592883,25597410,25601471,25611382,25613138,25619882,25620175,25625591,25627160,25636507,25639555,25639860,25639872,25640309,25645014,25650664,25659151,25660117,25661333,25661467,25662849,25665524,25691296,25695729,25698539,25701378,25701784,25702787,25704303,25704763,25714871,25719943,25726893,25729885,25736926,25745998,25753771,25757539,25760096,25762619,25775951,25777142,25784113,25784743,25791921,25814554,25815442,25816324,25830382,25835975,25846394,25846944,25847297,25862630,25862867,25862896,25862915,25874498,25877996,25880873,25886003,25893985,25896413,25896712,25897806,25909227,25915427,25922934,25925379,25931014,25943894,25954860,25960234,25961455,25962638,25964092,25982963,25987255,25990837,25996556,26004137,26022125,26026089,26030190,26044564,26047703,26051604,26070568,26071104,26075254,26087719,26088866,26108998,26109071,26123392,26125726,26137473,26139537,26149216,26150526,26158266,26170450,26178916,26195760,26203858,26208487,26213230,26235873,26243309,26256794,26260387,26265781,26267533,26283546,26286747,26302489,26318486,26344197,26364720,26386696,26390688,26391397,26393468,26427440,26435498,26496610,26499802,26505797,26631969	15		NP_001014431.1|MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA,NP_001014432.1|MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA,NP_005154.2|MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA,XP_005267458.1|MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA,XP_011534845.1|MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA,XP_011534846.1|MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKGP
13	HARBI1	283254	Putative nuclease HARBI1	HARBI1	C11orf77	human	NM_173811.3,XM_011520025.1,XM_011520026.1,XM_011520027.1,XM_011520028.1,XM_011520029.1	NP_776172.1,XP_011518327.1,XP_011518328.1,XP_011518329.1,XP_011518330.1,XP_011518331.1	NC_000011.10,NC_018922.2,NT_009237.19,NW_004929378.1	Q96MB7	Nucleus. Cytoplasm.	NULL		8453,23008,56904,7874	Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. {ECO:0000269|PubMed:15169610, ECO:0000269|PubMed:18339812, ECO:0000305}.	Hs.714463	12477932,14702039,15169610,15489334,16341674,18029348,18339812,20694011	15		NP_776172.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS,XP_011518327.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLDLPEFHWKDWLTVMSRTRIYSTFSSVNQGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS,XP_011518328.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLDLPEFHWKDWLTVMSRTRIYSTFSSVNQGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS,XP_011518329.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLDLPEFHWKDWLTVMSRTRIYSTFSSVNQGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS,XP_011518330.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLDLPEFHWKDWLTVMSRTRIYSTFSSVNQGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS,XP_011518331.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYYLVELLGANLSRPTQRSRAISPETQVLAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIRFPADEASIQALKDEFYGLAGMPGVMGVVDCIHVAIKAPNAEDLSYVNRKGLHSLNCLMVCDIRGTLMTVETNWPGSLQDCAVLQQSSLSSQFEAGMHKDSWLLDLPEFHWKDWLTVMSRTRIYSTFSSVNQGDSSFFLRTWLMTPLHIPETPAEYRYNMAHSATHSVIEKTFRTLCSRFRCLDGSKGALQYSPEKSSHIILACCVLHNISLEHGMDVWSSPMTGPMEQPPEEEYEHMESLDLEADRIRQELMLTHFS
13	RPS6KB1	6198	Ribosomal protein S6 kinase beta-1	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	human	NM_001272042.1,NM_001272043.1,NM_001272044.1,NM_001272060.1,NM_003161.3,XM_006722010.1,XM_011525101.1,XM_011525102.1,XM_011525103.1,XM_011525104.1	NP_001258971.1,NP_001258972.1,NP_001258973.1,NP_001258989.1,NP_003152.1,XP_006722073.1,XP_011523403.1,XP_011523404.1,XP_011523405.1,XP_011523406.1	NC_000017.11,NC_018928.2,NG_029513.1,NT_010783.16,NW_004929407.1	P23443	Cytoplasm.	NULL			Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTORC1) leads to dissociation from the EIF3 complex and activation. The active form then phosphorylates and activates several substrates in the pre-initiation complex, including the EIF2B complex and the cap-binding complex component EIF4B. Also controls translation initiation by phosphorylating a negative regulator of EIF4A, PDCD4, targeting it for ubiquitination and subsequent proteolysis. Promotes initiation of the pioneer round of protein synthesis by phosphorylating POLDIP3/SKAR. In response to IGF1, activates translation elongation by phosphorylating EEF2 kinase (EEF2K), which leads to its inhibition and thus activation of EEF2. Also plays a role in feedback regulation of mTORC2 by mTORC1 by phosphorylating RICTOR, resulting in the inhibition of mTORC2 and AKT1 signaling. Mediates cell survival by phosphorylating the pro-apoptotic protein BAD and suppressing its pro-apoptotic function. Phosphorylates mitochondrial URI1 leading to dissociation of a URI1-PPP1CC complex. The free mitochondrial PPP1CC can then dephosphorylate RPS6KB1 at Thr-412, which is proposed to be a negative feedback mechanism for the RPS6KB1 anti- apoptotic function. Mediates TNF-alpha-induced insulin resistance by phosphorylating IRS1 at multiple serine residues, resulting in accelerated degradation of IRS1. In cells lacking functional TSC1- 2 complex, constitutively phosphorylates and inhibits GSK3B. May be involved in cytoskeletal rearrangement through binding to neurabin. Phosphorylates and activates the pyrimidine biosynthesis enzyme CAD, downstream of MTOR. {ECO:0000269|PubMed:11500364, ECO:0000269|PubMed:12801526, ECO:0000269|PubMed:14673156, ECO:0000269|PubMed:15071500, ECO:0000269|PubMed:15341740, ECO:0000269|PubMed:16286006, ECO:0000269|PubMed:17052453, ECO:0000269|PubMed:17053147, ECO:0000269|PubMed:17936702, ECO:0000269|PubMed:18952604, ECO:0000269|PubMed:19085255, ECO:0000269|PubMed:19720745, ECO:0000269|PubMed:19935711, ECO:0000269|PubMed:19995915, ECO:0000269|PubMed:23429703}.	Hs.463642	1922062,8871403,9271440,9427642,9445476,9465032,9653190,9804755,10089566,10197603,10200280,10567431,10601311,10807185,10971657,10973943,11013237,11171059,11279232,11297520,11331760,11438723,11500364,11516946,11733037,11774034,11853558,11914378,12014987,12019261,12023960,12052877,12054624,12150925,12150926,12477932,12529391,12586835,12604610,12718876,12733712,12747804,12759354,12801526,12869548,14673156,14679009,14702039,14709557,15024086,15028555,15066126,15071500,15149849,15158097,15203190,15236312,15249583,15304500,15314020,15319361,15341740,15342556,15474452,15533996,15589845,15623621,15659381,15692808,15696579,15723049,15760907,15790787,15809305,15812314,15843522,15854902,15896331,15899889,15905173,15953364,16049009,16109716,16183647,16262259,16286006,16364302,16407298,16434552,16469801,16640565,16715128,16763566,16810323,16818690,16826166,16837165,16839745,16883576,16895915,16899564,16914728,16922504,16931574,16962100,16964243,17043309,17045920,17052453,17053147,17081983,17255101,17310252,17336708,17386266,17427199,17512525,17569770,17599906,17604271,17616691,17622239,17693255,17908691,17936702,18025271,18279656,18423201,18451027,18461003,18505677,18550814,18565837,18652687,18660489,18813808,18829578,18952604,19065636,19085255,19112174,19168580,19171678,19240722,19266162,19285034,19322201,19402821,19553685,19730801,19801633,19815051,19864428,19881535,19889638,19913121,19914247,19936974,19953087,19961954,19995915,20137651,20157535,20173664,20187284,20190034,20374740,20410302,20423989,20433920,20459645,20599538,20599721,20617335,20628086,20657550,20731018,20819778,20932932,20953835,20961652,21035469,21048031,21067588,21071439,21075311,21093473,21184268,21224254,21228102,21258406,21289241,21292829,21297943,21390332,21397856,21424608,21440577,21444676,21460630,21467264,21536668,21541441,21561857,21602892,21609291,21710263,21757621,21832049,21833088,21900206,21981924,21986499,21988832,22110663,22113269,22248270,22286763,22348058,22391570,22439934,22442669,22457523,22493283,22544753,22574368,22645648,22684641,22705322,22795649,22797923,22871496,22939624,22977662,23044732,23045529,23128233,23184942,23251661,23273915,23276696,23330000,23376066,23393338,23443539,23632629,23639457,23731517,23739915,23816567,23886172,23938603,24023352,24030155,24058693,24067973,24089522,24157791,24239466,24247430,24277938,24280132,24287118,24332215,24337579,24396066,24440085,24447434,24456794,24469069,24501087,24582588,24606695,24648513,24652283,24661902,24675012,24729449,24859886,24860943,24875531,24887566,24901052,24936148,25061101,25118997,25134527,25165983,25220053,25241761,25311616,25356520,25379021,25600244,25635535,25659153,25762619,25784113,25846498,26169935,26235873,26427479,26468204,26496226,26496610,26506538,26626074	15		NP_001258971.1|MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL,NP_001258972.1|MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSTAMC,NP_001258973.1|MDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL,NP_001258989.1|MAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL,NP_003152.1|MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL,XP_006722073.1|MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAVAPIHWGE,XP_011523403.1|MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL,XP_011523404.1|MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLVHHPDLCLHVHMVFYLSI,XP_011523405.1|MALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL,XP_011523406.1|MALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
13	Harbi1	241547	Putative nuclease HARBI1	Harbi1	D230010M03Rik	mouse	NM_178724.4,XM_006499470.1,XM_006499471.1,XR_866273.1	NP_848839.2,XP_006499533.1,XP_006499534.1	AC_000024.1,NC_000068.7,NT_039207.8,NW_001030694.1	Q8BR93	Nucleus.  Cytoplasm.	NULL			Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity (By similarity). {ECO:0000250, ECO:0000305}.	Mm.130331	10349636,11042159,11076861,11217851,12466851,12477932,14610273,15169610,15489334,15741177,15782199,16141072,16141073,18799693,21267068	19		NP_848839.2|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYFLVELLGASLSRPTQRSRAISPETQILAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIHFPVDEAAVQSLKDEFYGLAGMPGVIGVADCIHVAIKAPNAEDLSYVNRKGLHSLNCLVVCDIRGALMTVETSWPGSLQDCAVLQRSSLTSQFETGMPKDSWLLGDSSFFLRSWLLTPLPIPETAAEYRYNRAHSATHSVIERTLQTLCCRFRCLDGSKGALQYSPEKCSHIILACCVLHNISLDHGMDVWSSPVPGPIDQPPEGEDEHMESLDLEADRIRQELILTHFS,XP_006499533.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYFLVELLGASLSRPTQRSRAISPETQILAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIHFPVDEAAVQSLKDEFYGLAGMPGVIGVADCIHVAIKAPNAEDLSYVNRKGLHSLNCLVVCDIRGALMTVETSWPGSLQDCAVLQRSSLTSQFETGMPKDSWLLGDSSFFLRSWLLTPLPIPETAAEYRYNRAHSATHSVIERTLQTLCCRFRCLDGSKGALQYSPEKCSHIILACCVLHNISLDHGMDVWSSPVPGPIDQPPEGEDEHMESLDLEADRIRQELILTHFS,XP_006499534.1|MAIPITVLDCDLLLYGRGHRTLDRFKLDDVTDEYLMSMYGFPRQFIYFLVELLGASLSRPTQRSRAISPETQILAALGFYTSGSFQTRMGDAIGISQASMSRCVANVTEALVERASQFIHFPVDEAAVQSLKDEFYGLAGMPGVIGVADCIHVAIKAPNAEDLSYVNRKGLHSLNCLVVCDIRGALMTVETSWPGSLQDCAVLQRSSLTSQFETGMPKDSWLLGDSSFFLRSWLLTPLPIPETAAEYRYNRAHSATHSVIERTLQTLCCRFRCLDGSKGALQYSPEKCSHIILACCVLHNISLDHGMDVWSSPVPGPIDQPPEGEDEHMESLDLEADRIRQELILTHFS
13	ATG13	856315	Autophagy-related protein 13		APG13	baker's yeast	NM_001184282.1	NP_015511.1	NC_001148.4	Q06628	Cytoplasm. Preautophagosomal structure.	NULL		64422,23192,79016,1642,4131	Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Required for autophosphorylation of ATG1 at 'Thr-226' and its dimerization. May also be involved in the regulation of autophagy through SNF1. Involved in ATG9 and ATG23 cycling through the pre- autophagosomal structure. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase. {ECO:0000269|PubMed:10837477, ECO:0000269|PubMed:10995454, ECO:0000269|PubMed:11086004, ECO:0000269|PubMed:11486014, ECO:0000269|PubMed:14723849, ECO:0000269|PubMed:15743910, ECO:0000269|PubMed:17295840, ECO:0000269|PubMed:17426440, ECO:0000269|PubMed:17699586, ECO:0000269|PubMed:18077553, ECO:0000269|PubMed:18287526, ECO:0000269|PubMed:19805182, ECO:0000269|PubMed:19995911, ECO:0000269|PubMed:20439775, ECO:0000269|PubMed:20647741, ECO:0000269|PubMed:20855505, ECO:0000269|PubMed:21468027, ECO:0000269|PubMed:21712380, ECO:0000269|PubMed:22447937, ECO:0000269|PubMed:22778255, ECO:0000269|PubMed:22782902, ECO:0000269|PubMed:22885598, ECO:0000269|PubMed:8224160}.		8849441,9169875,9224892,10688190,10837477,10888680,10995454,11486014,15743910,15901835,16824055,18077553,18245329,18287526,18701704,18805955,18829864,19337029,19793921,19805182,19840948,19995911,20093466,20489023,20953146,21460632,21712380,21987634,22768199,22778255,22782902,22885598,23222640,23322149,23509291,23549786,23904270,24440502,24586198,24793651,25139988,25998554,26061644,26673895	28	1->53,125->237,271->283,343->738	NP_015511.1|MVAEEDIEKQVLQLIDSFFLKTTLLICSTESSRYQSSTENIFLFDDTWFEDHSELVSELPEIISKWSHYDGRKELPPLVVETYLDLRQLNSSHLVRLKDHEGHLWNVCKGTKKQEIVMERWLIELDNSSPTFKSYSEDETDVNELSKQLVLLFRYLLTLIQLLPTTELYQLLIKSYNGPQNEGSSNPITSTGPLVSIRTCVLDGSKPILSKGRIGLSKPIINTYSNALNESNLPAHLDQKKITPVWTKFGLLRVSVSYRRDWKFEINNTNDELFSARHASVSHNSQGPQNQPEQEGQSDQDIGKRQPQFQQQQQPQQQQQQQQQQQRQHQVQTQQQRQIPDRRSLSLSPCTRANSFEPQSWQKKVYPISRPVQPFKVGSIGSQSASRNPSNSSFFNQPPVHRPSMSSNYGPQMNIEGTSVGSTSKYSSSFGNIRRHSSVKTTENAEKVSKAVKSPLQPQESQEDLMDFVKLLEEKPDLTIKKTSGNNPPNINISDSLIRYQNLKPSNDLLSEDLSVSLSMDPNHTYHRGRSDSHSPLPSISPSMHYGSLNSRMSQGANASHLIARGGGNSSTSALNSRRNSLDKSSNKQGMSGLPPIFGGESTSYHHDNKIQKYNQLGVEEDDDDENDRLLNQMGNSATKFKSSISPRSIDSISSSFIKSRIPIRQPYHYSQPTTAPFQAQAKFHKPANKLIDNGNRSNSNNNNHNGNDAVGVMHNDEDDQDDDLVFFMSDMNLSKEG
13	VOLCADRAFT_95367	9624850				volvox	XM_002954444.1	XP_002954490.1	NW_003307586.1	D8U794	NULL	NULL		60673,3281,9776,27316,6117,6118,6294,9667,140775,29110,56252			20616280	81		XP_002954490.1|MTVPAFLLELDEVDGVGKEVEVWRKDISSPLVIEIHMAPGGVAAALAAAAAASAAGPSGGGGSCLPAGGGGGGAAAVAAAADYFGSLAVQLRPGASRVQAIQDGQGSGGACQRSAGEQFQFQLQYRIYRTLQQAVGSDGGGALCGDGDTLPRPPPPRLQDFAFAPVDTPGGRFRVAVQYNPAATALVLEHSTAPMAMPYTLNENYLGPFGAAAAAAGGSLGPPAGSRGPYGTQPFPGTSAPSSAGMAAARHMRPAMSTSLSGPTTAVLMGRSPPADGGILRHAPSAGSFGVGGIVPGSGAAAASAAGGGGGGGGVPAAGGPAAPPRVIVRQSWSSKEMKVSFSLPPPLGSPGGLGGGGGGGVAGGFRRSSSVPVESSSVPTSAFAVPAWQHKMMAAVQGREEGGGGATAATAAMEVSGTATTGRSMAAAAPAGAEDSATAAAAAAGSSSSSAGGGSGVTSRVVDATAAATATGAVGDAAGVSPAVAGVSLYDEYDGSRGGEGDDAAAAGDRSSGGGSSGGGGTRQSTAAVLGVGGTGSGTASRTTSAPLAIPSRSSSRTRSVVDLRAPAVYGGFEHRMAPGSAPAAPRGMLGLALGAMKPGGARGSGIGGGGAAAAASPSISSDAAAEAAVTSGAADGGKADRAADASASLMSLASLHQAMVPLGYFAGHVAPPGAGGVGGGGGGVVGPARGVSGRDITYLATIRRPSWSSRSGSLDPSLASAGAAGPLMASLSPLRDLLESSYSNPSTPGGPRMRPDSADQPRRTSQRHRDPSSSSTSAIFSLSPSSSAVPGTSPAVHLHHLHHQHQRRGAAARAAATTAAAAEGSGAGGGGGGEGTGLAADSTDSAAAAAAAMRAGPGAAADSATTGAAGDRGAARGMGNGSAAAAAVAAENMDVAEPTEDVVPYDLYGTYGDPDVDARTCPLIREDSESDLLPFALDQEGLVLGPGAAGGGGPAAAMLTAAAAAAGARATAPTGGRPRVAGHPAAGPIELTLSIAQARERDVAVGAFVRMMADAAPLAAAPEHPAVREYSPREALLELQQLGNRIQAALEAAAPQLQMAAAAAAAAAPPPAPQPPQSYWGLAPPGGAGPCSFAASWCRRIRSHDRTRRLLGASVRLPLG
14	Atg14	43438		Atg14	CG11877|DmelCG11877	fruit fly	NM_143412.3	NP_651669.1	NT_033777.3	Q9VAP6	NULL	NULL				Dm.4449	10731132,12537568,12537572,12537573,12537574,16110336,17569856,17569867,20798940,20980240,22036573,22330894,22562043,22952930,24389064,24949430,25006588	12		NP_651669.1|MANSSSSDESCKAPDNFRISSASTNGEDEESDVAGYTTKRRPTAATKELLKDANAKDRNATTGMGAHMRCPLCHSCSASRFHCRNCVRNGNITHSQAERPESLTEKQQRYINLQAGLKTFSTRYERLIGQHRSNEDRLMAIKAKRKQLELLQQLISGTGQRLRVLGERRDELRRANAEKRKNLPKYPDKVKMLENYVLDRVEKIEKLRETHLGLLDSIKQAARRSIQQLVTYVFPIAEVVLKEEQQRRASVERTEEAETIAALADAKNTSYIRGKWVFHGSGISEVQYRIVGPSLPANGDYTAYLDWLADNKDDVPKATANEITPSRFEAYRIVGALTYTAQLTQLLSFYLNVRLPHKIAYGDFCRKLLNEEQFRRKISRLNSNIMYLAYTQQVKLRALIEQHTLENLLAILDLERSDLGRYGHLDVNNAPLMKSVDSLLIGIETATESESEDENSLRMDWEAVPSLTPQPELADPNLMPAANQQSTIAFVRMAATSVLRWIK
14	ATG14	22863	Beclin 1-associated autophagy-related key regulator {ECO:0000303|PubMed:19050071}	ATG14	ATG14L|BARKOR|KIAA0831	human	NM_014924.4,XM_011536563.1,XM_011536564.1	NP_055739.2,XP_011534865.1,XP_011534866.1	NC_000014.9,NC_018925.2,NT_026437.13,NW_004929393.1	Q6ZNE5	Cytoplasm. Endoplasmic reticulum membrane.	NULL			Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t- SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity). {ECO:0000250|UniProtKB:Q8CDJ3, ECO:0000269|PubMed:18843052, ECO:0000269|PubMed:19050071, ECO:0000269|PubMed:19270696, ECO:0000269|PubMed:20713597, ECO:0000269|PubMed:23878393, ECO:0000269|PubMed:25686604}.	Hs.414809	10048485,12477932,14702039,15489334,16751776,17081983,18843052,19050071,19270696,19322201,19460752,20562859,20711182,20713597,21062745,21241894,21518905,22081109,22314358,22493499,22797916,22992773,23197835,23262492,23332761,23878393,23954414,24034250,24337183,24785657,24980959,24980960,25127057,25490155,25594178,25686604,25825496,25891078,25906440,26186194,26496610	15		NP_055739.2|MASPSGKGARALEAPGCGPRPLARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSRLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRIEQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVSPSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRFCDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR,XP_011534865.1|MSCKMRIEQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVSPSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRFCDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR,XP_011534866.1|MHPVENKIPRDWLSSQAIMASPSGKGARALEAPGCGPRPLARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSRLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRIEQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDVNLPKKLCNSVQIFV
14	Atg14	100504663	Beclin 1-associated autophagy-related key regulator {ECO:0000250|UniProtKB:Q6ZNE5}	Atg14	4832427M01|Atg14L|D14Ertd114e|D14Ertd436e	mouse	NM_172599.4	NP_766187.1	AC_000036.1,NC_000080.6,NT_039606.8,NW_001030552.1	Q8CDJ3	Cytoplasm. Endoplasmic reticulum membrane.	NULL			Required for both basal and inducible autophagy (PubMed:19270696, PubMed:19270693). Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (By similarity). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:19270693). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (By similarity). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (By similarity). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation of PIK3C3 by AMPK (PubMed:23332761). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (By similarity). Modulates the hepatic lipid metabolism (PubMed:22992773). {ECO:0000250|UniProtKB:Q6ZNE5, ECO:0000269|PubMed:19270693, ECO:0000269|PubMed:19270696, ECO:0000269|PubMed:22992773, ECO:0000269|PubMed:23332761}.	Mm.287279,Mm.470462	8889548,10349636,10725249,10922068,11042159,11076861,11217851,12040188,12466851,12477932,12520002,14610273,15368895,15489334,15782199,16141072,16141073,18799693,18843052,19270693,19270696,21220506,21228623,21241894,22493499,22797916,22992773,23332761,23455425,24089209,24185898,24849286,25821988	19		NP_766187.1|MASPSGKGSWTPEAPGFGPRALARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSQLKNKQEEFQKEVLKAMEGKRLTDQLRWKIMSCKMRIEQLKQTICKGNEEMKKNSEGLLKNKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLKSHYERLARLRRSHILELTSIIFPIDEVKTSGRDPADVSSETDSAMTSSMVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYNWVEEKKTTQGPDMEHNNPAYTISAALGYATQLVNIVSHILDINLPKKLCNSEFCGENLSKQKLTRAVRKLNANILYLCSSQHVNLDQLQPLHTLRNLMHLVSPRSEHLGRSGPFEVRADLEESMEFVDPGVAGESDASGDERVSDEETDLGTDWENLPSPRFCDIPSQPVEVSQSQSTQVSPPIASSSAGGMISSAAASVTSWFKAYTGHR
14	ATG14	852425	Autophagy-related protein 14		APG14|CVT12	baker's yeast	NM_001178476.1	NP_009686.1	NC_001134.8	P38270	Preautophagosomal structure membrane.	NULL			Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I. This complex is essential to recruit the ATG8- phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure. ATG14 mediates the specific binding of the VPS34 PI3-kinase complex I to the preautophagosomal structure (PAS). {ECO:0000269|PubMed:10547367, ECO:0000269|PubMed:11157979, ECO:0000269|PubMed:11382761, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:15004240, ECO:0000269|PubMed:16267277, ECO:0000269|PubMed:16421251, ECO:0000269|PubMed:16565503, ECO:0000269|PubMed:19445518, ECO:0000269|PubMed:20855505, ECO:0000269|PubMed:21703229, ECO:0000269|PubMed:22718752, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:8663607, ECO:0000269|PubMed:9712845}.		7813418,8849441,8901576,9712845,11157979,11805826,15879519,16421251,16554755,17923092,18701704,19269370,19445518,19840948,20093466,21121900,21987634,22437838,22875988,23129774,23209445,23891562,23904270,24165940,24586198,25519895,26061644	28		NP_009686.1|MHCPICHHRAHVVYCAHCINTSPSLLLKLKLDLILLKDENKELNGKVEQILNEAMNYDQLDIKRMEKKKDPLMNSLMKLDVLRMKKNNNLIRHRIEQLNERIYSKRNHISELKVEIDNYKCYKVGTGTDKLREQVEISDAKNKLAQVSKICESARDYKLNLLNNWFVIQKLQDNFQIPFAIAFQPLISLKNFRILPLAITNDSINIMWKYISFFSDILMIKLPYTNKICEQPMFEFSDSIQTVVQRLIKLIINILQICRHLKLVPSTPMDIPWLLDQYDVDGLFYNMVKRNKMKCRSVSLYWTFGMLYSMVLDNMNNPQRGHPARRTAPPPTVTGPHDRWYVVG
14	VOLCADRAFT_105732	9627733				volvox	XM_002952966.1	XP_002953012.1	NW_003307576.1	D8U2P5	NULL	NULL				Vca.3698	20616280	81		XP_002953012.1|MLLELNERRASLLERLNGLLTQRQTHVELEVRRQHLVAAAAREQARVQQAAAAVEEALFPWQQLHSLVALTHSHVAAMLLAEQRSKLAVLLDTLPLRVAAIRPPPQPPAQPQLPIQQPTAFNQQQQQQPQGASAGVFPKPNHPNQQQPGLQGSPSLIGPVAPGLGPAPSSAGAGAGGGGMGGGGSGHGGVAGSSPIQVTLCNMKLPDGATVSSLMAAQPESTSSALGYLLLLAELLSTYFGGPILHEGSFQGSTSVIWQQHSFWNRRPSTSNGRLPLFLEEGGGGGGGGGGGGGGGGGPGLSNPFPGLATKVRGPSPWTSQPSGHQHQYQQSQNQQPGTSHSQQHQQPQTQLQQHHGYSHLSAGGAAASAFSALTRVMSGGIAAAAGGAGGGGVSYIPQVEEALVRQRHTDLRLAYDMLLRSLACFTRDKIVPLGLQLPNSWGPLGWLAVLCASVRRDPGTDAVLVAAQQALAAQQGGQMAVGGLMGQGGGGGFTARDHLRPGLAAGGLAAAVAAVGDGGGGGGFQDNDGCTFCTLMSGFGAFFMFLLGICISNNYEYVGEWYKPEKGRGSPTTDQIKEAAKNCFITGGVYIAFTIMAAMCVCYQNKKAKRT
14	VOLCADRAFT_89218	9623595				volvox	XM_002948844.1	XP_002948890.1	NW_003307554.1	D8TR41	NULL	NULL					20616280	81		XP_002948890.1|MDLEAVGWRPARRLRHVTAVCLHNLYDPAFDGASGYFYELCTWDAQQWAWSRFYRSEQLANNRDLDWARQRLDPDTETMLQGVHHRPDVGPLRLRVYATCNDSTAPKSNSTTVATTLRPSSGSWPVGQNAADAAAAADDDDDDVLPNRSSSDYEAQHLPRLRRQADCCIARNGVGMAHVLRPPLQPSPPPLPLLPQPHTAARLSPVHVSAAGDSSGTAGNDGVSGQCWEQSRLGVGLGTICTSTEPLEAVVERSWGKVSGPGPPSLQLQQQSHQQPDLQTDITSAFGAPAAMQQSREGSGGEDTYQGDKVQLGQGQRQGQGETKHVTRQQGDVHMPRERDHQRQQQQQEVEKEEQQQQQQEQDGRYTVVCAGSLRAQNPAGACPDADVVAATAEVMPAPPASPGGPNGTCSSGPGPGASSACSGSSSRSRSSDFGAVRKEVSAGQLSNGGGSGPGSCEADIGAVDVGAASEANCVGGNLHGRAAVAAAASVAAVASALPQLLDAPAPPWEGSRGNAGGGQAAPDGGGFTCRRKHQEQEQEPEPGQGPQPPRLQLDWDMKMAPGVQRQTCEAEDPVSVRVDETDPQPTPPTEPAQPAEAATATGPSSTSSSSSSTSSSPACSLSSPSCPPGSVTVGELSAVGGSLLGVREVQHVVVCAHPTEVGCAGGSGGDVGRGGGGGVGGGPTPEQAALQEPEDDGGIGHQEGGYSDVGEQCDGEHERYRMNEERYGGDEEGVRWGEEEGSYDGGDGSGDGGGMRLLVEHVFELRELVFLDPRMLRHGWYINLPLLLMEPGRQPFVPPCALPPPPPPPRPPPRSEDDKRALLRWLLSSSSVVQPLQAVGSLEEELQNDDFLASAAAAAEPAATSAVPADGRHLHSPHLHHAHHVHLRPPALHHTGNANPHQRSLSAADAAALLDPGPIPGFLPSALAVLFRQEWPWGSAAAAAAAIAPPAGPPGLRQSSSRQGLEQPLPPTAATPAAAAAASERGSCGRASPGSRRVASTPSLAVVAEVEADAEAAEVTVDSAPGAGRLAGSAATLGSLLRPSGGSAGDFVRTWSGGDADSGSLSAPASPSSSAVSYIAAAAAAAAATLGGPAAASSLASDGGSQTSLTSLAGGRAASPSLPSPSGTNNQELPSEGLAAVQHSWLPAALLPPRRPASRSLRPFASSGQLTGGGAAAGGGGSGGAGPTAGLTAGDSQPPLIDSAAAKRGPAAAAAAVRGRKRAPLGRGPAPQSAAAAPPTNHYHNHHNHHNRGQGHNHQPYFAAAAAATSTAAAAVAPSVQRLCELVEVRANIGKLTQLQERLTATRAGALGVRRRLEAAAERRHLLDDVRARAEAVRVEGRGWSVRVDGMEAQLRAMRAEAVRRRHELHDRARALETAARVLQAAEQRRLSALEQLEGPSGRGHLAELTAALAGRRNRLVSELGRIFQIGPISESLLDPDPLDQTLDSSWAGEWARTAGDWDRQTQQHPQPQREEKASGGKQGAEEDGHPGGGGGGGAEGGPQTRQGGEEERAAGQQTPEGTEGAAMAVSAPSGSASLSGKLRGSNGGGGGGGGGPALGGGRGGDGGGGPTRLAIMGLELPPNLIERSLHGSVGWSPLDLGRRYDADQRTAAGLGYLAAIVDLAATYLGVPLRYPIAPRVSVSYISDPVPPSASVRSGAAAPVAAVAPLAAAALPGAGGAGAAAAAGRGAEWRLLTIATGSLNAVAAAAGPAPPPLPAPPPFAVGLIPGPRGVGVGGRLAVFSSILNANLDPWVATTPAGAVGDDAHPVGLNPAAGLPLFWGDGARDRTRFAYAVYLLSKDVEQLLESHGIPPIAPNQPLPNLYVLISAAASGVSRRAGRGGGGVGGVGGSGTSR
15	ATG15	850432	Putative lipase ATG15		AUT5|CVT17	baker's yeast	NM_001178779.1	NP_009994.2	NC_001135.5	P25641	Endoplasmic reticulum membrane.	NULL			Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension. {ECO:0000269|PubMed:11085977, ECO:0000269|PubMed:11264288, ECO:0000269|PubMed:11566994, ECO:0000269|PubMed:12499386, ECO:0000269|PubMed:18690010, ECO:0000269|PubMed:21364763, ECO:0000269|PubMed:21777356}.		1574125,8849441,11085977,11566994,12499386,14657499,16093310,17923092,18627629,18701704,18719252,18806213,19840948,20093466,21196517,21552543,21987634,22282571,22384331,23209445,24586198,25187651,26061644	28	1->11,35->58,96->166,233->295,337->370,471->520	NP_009994.2|MLHKSPSRKRFASPLHLGCILTLTVLCLIAYYFALPDYLSVGKSSSRGAMDQKSDGTFRLKSIYRHGVGANHRLHQRLEVTPEVISAAGMLYQETTTQGQDFEDQEPLWTTNAEYATTNPFDFEFELRRMPLLMKRMKERDPEFIESYIYGETYMTEEEEHAMWIDDDIVAPNITDRGTVVSLALMSSNAYVRIPQTGDWRNVTEPWNETEPEDFGWDGDGIRGHVFYNEVENIVVLSIKGTSAQGLPGSGEDETTGNDKINDNLLFSCCCARVSYLWTTVCDCYVKSYICDESCLEKELRRKDRFYSAVVDIYKGVLKEYPDAAIWVTGHSLGGALASLLGRTFGLPAVAFESPGELLPSKRLHLPFPPGLPSYMEGIWHFGHNADPIFMGTCNGASSSCSLVGYAMETACHTGRVCVYDVVNDKGWSVNMFNHRIHKVIDEVLLGYEQAAKCVEPEPCVDCYNWKFIPSRDWESSSRLITKTKSHAAPTTTTRTTATTTSSSTCVGRNWLGFCTKYEL
15	VOLCADRAFT_101426	9614936				volvox	XM_002959861.1	XP_002959907.1	NW_003308425.1	D8UMM1	NULL	NULL					20616280	81		XP_002959907.1|DIFSLGCVIAEVFCDGKALFDLSALLSYRRGDAAADLASGGALAAVDPDIRRLVLHMIQLDPAARWPAAKYLSDWPEPLFPPYFSSVLHPFFASLLPLDADARVAATAAAFPRLRREILAAAAAVTPSSAAEKAAAATAAPAGSTGLADGMTAQPLQPPATSRQQQDGATGTAVSAVAAAVVSAAAAPPPPSGNSGSGGMLVSGAAAGGVGSGTAGLWSLLDEVGALLADNGSMVRRFKVREPWGNWQGASSDDDMALLGCAVGGAGGGRAGGDGGGGGSSSSAWRGREEVELPRGGGWQWAGEWTVDMRGGQPHGGGPAAAAATTLLVDADGWEYRSTT
15	VOLCADRAFT_105099	9615536				volvox	XM_002951406.1	XP_002951452.1	NW_003307566.1	D8TYF1	NULL	NULL					20616280	81		XP_002951452.1|MSQLATTKRQASIGWPSLQQSIASGSTVDRQPHLVEVKSYLETYQGELQWLSISAELWPKDCQGSRQLHREFSVLSTSQPHPNVVVGLVGASVGSSGRPRLVTEYVPRCLSSELRTRGYGGLSGPEVKLLAWQLAQTIKHLHDKKIIHRDIKPANLLLDDAGVLRLCDFGSARFISSMREVPYDKDADAVLRVAARRYKAPEILIKQCHGPAADVWSFGCTVAELASGRPLLPGSSDADQMIRIMKFCGLPPYDPYGYLRASLSRNADVSRPVSPQLLSLLESCLRLDPNDRRTMDEILRSSYFSDVPLLIQGTELACLYDIQVEPFISLRGVQSADNSNNNNNACNNGCFKINSKWSSSKHIAMASPPRIPGSRTGAVPSAPSPPLTPTTLPPPPPPLSSPPSPSRPSPPRPVSPWAC
15	VOLCADRAFT_44867	9622004				volvox	XM_002945587.1	XP_002945633.1	NW_003307545.1	D8TH09	NULL	NULL					20616280	81		XP_002945633.1|QLASIAYCSHPDLLAAWNCTRCVGLPGFTPHRVVYDTVWDLAAYAGYYAPWDAVVLSFRGTDSSNWGQWAENMRAWRTDHMYPVPDFPHAFIHAGFYTLWTGSSLQATFTAAVSELMAVHPKARLVATGHSMGGALAQLAGLEFKLSYNTTHTTVYTYGAPRVGNVAYQQLFNSFVDISWRFTHNRDIVPSVPLQLMGFQHVAREVWEVDVEDPSRAGGVERKLLMCDASGEDPSCHNSACYLGLCTSIADHLLYLGLHMYQDS
16	atg-16.1	180717	Autophagic-related protein 16.1			nematode	NM_076367.3	NP_508768.1	NC_003284.9	Q19124	NULL	NULL				Cel.11058	9851916,22862955,24185444	5		NP_508768.1|MQTRSIDNVVNWSRCVHPSCVAWVIFIHFCFAKNCSILYFVLFQFTFFAELMADSYRKLIIERLEDVKQRNKQTATLYNNYSKLAEQLEKKHKYGTSSSNSSQLETGELARVKEEMAELYRSKCQNDQRLIDANHRIADFEKKSSAIIAEKIALEATAKSICAKYAKTEVELQRLKVDNDQLNDERIASNTTVTMLTKQIQDIENDRIHFLNKIRELNEQRVDFLNAEVALEEKRRNSRIQDMITSAVQDITDKDTKLEEMLRAMPDTNSNGDLLLGDSVPSRAEFVLECEEGEVNDVHWLDGETFATGGSDRNIKIWKVDGHGGYTRIGTLAGSNAAFTRIDYERDRKHFIASSNDKNVRIWNLDNSRLLSTLSGHSDQVTCVKFYQSHSAVSGSADRVIKIWDIQNQRCSRSLFPASKVLDVATNMGASPSLFASGHFDKKLRFYDGRSTDPVRTVDMGGRITSLDVTMSGCELLVSTRDDTISLIDLRTFQTVHCYSAENYRTSSDLSRVVLSSGNEYVAAGSSNGSIFVWNRNSTKLEKQLCSNSENAIFSLSWNPTGYGLLSSSKQKFVTLWK
16	atg-16.2	174067	Autophagic-related protein 16.2			nematode	NM_062898.3	NP_495299.2	NC_003280.10	Q09406	NULL	NULL				Cel.7602	9851916,14704431,19557190,22862955,23392608,24185444,24882217	5		NP_495299.2|MTDNRTSFRLEILNRLCKRERQQRCVKDMFKNYSLLDEQLQQSHRSRSVSVNDEHFKGNVNDRLAVMKEEMANVYRMKSKNDQDLIDANRKLADSESRYSLVSSQRDKLRIETDAIVKKMTVLENELAELKEENSVINTERVSLVATCNYLTEKKTQLDNERFQLLNRIRELQEKSAEFMNAEIALQEERAQMRIREQIAKATADLNLGDERASSAFGTSPETLDEFMMTDVLPSEVKFKLSTHDGEVHDVEWMSDDTFATAGSDSKVQIWRVSPNKTDASKVSTLSGCLGPVNRLDYDSQRHVCLASSNDKTCRLWNIDSQRLLSTFSGHTDKVSSARLFQSHNVISGSADRTIKNWDISSIRCLKSYLVGSTVFDIVAKCGVSQSSFISSHFDKKVRFWDARSSDATYSVELGQKVSSLDISMDGLQVLASSRDDTLSLIDVRNYGIIHLYSAEQYKTSCDSTRAIFSSTGEYVLAGSSNSSVFIWNTKTTKLEKVVKTARSDSAQIMSLAWNPSGRGLLACDRQKTCTLWR
16	ATG16L1	55054		ATG16L1	APG16L|ATG16A|ATG16L|IBD10|WDR30	human	NM_001190266.1,NM_001190267.1,NM_017974.3,NM_030803.6,NM_198890.2,XM_005246082.1,XM_005246084.1,XM_005246086.1,XM_006712608.1,XM_011548853.1,XM_011548	NP_001177195.1,NP_001177196.1,NP_060444.3,NP_110430.5,NP_942593.2,XP_005246139.1,XP_005246141.1,XP_005246143.1,XP_006712671.1,XP_011547155.1,XP_011547	NC_000002.12,NC_018913.2,NG_023038.1,NT_005403.18,NW_004929306.1,NW_011332690.1	A0A024R494,A0A024R4B6,E7EVC7,Q17RG0,Q53SV2,Q676U5	Cytoplasm.  Preautophagosomalstructure membrane.	NULL				Hs.529322	11181995,12477932,12665549,12975309,14702039,14743216,15489334,15620219,16344560,17200669,17353931,17435756,17455206,17484864,17534574,17554300,17625155,17894849,17921695,18047540,18088053,18162085,18166373,18200510,18338763,18366306,18438406,18448665,18495612,18499543,18521914,18521924,18587394,18671817,18698678,18715515,18824555,18849966,18852889,18985712,19120485,19139628,19174780,19235913,19262523,19269148,19276991,19322201,19334001,19337756,19422935,19491842,19575361,19590455,19659808,19683022,19760754,19783656,19898471,20014019,20024904,20066736,20082483,20222171,20380008,20395867,20417604,20485703,20562859,20570966,20637199,20639872,20697744,20722066,20839241,20846217,20875485,20886065,20962850,21072187,21102463,21206965,21406388,21513755,21618365,21674723,21734790,21832049,21879234,21987459,22275320,22302078,22342342,22346247,22370477,22412388,22573572,22658674,22863883,22885761,22936669,23128233,23202584,23262492,23300079,23376921,23392225,23434281,23439083,23512522,23535819,23633462,23850724,23964099,24022642,24036151,24076061,24086718,24100292,24238340,24401604,24413169,24522266,24553140,24563254,24627602,24656308,24713404,24715166,24791954,24954904,25003259,25048429,25060858,25159710,25233411,25253126,25461811,25484072,25712183,25738374,25767270,25825496,25883416,25886994,25891078,26095365,26165754,26186194,26344197,26347139,26673895	15		NP_001177195.1|MAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,NP_001177196.1|MQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,NP_060444.3|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,NP_110430.5|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,NP_942593.2|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,XP_005246139.1|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,XP_005246141.1|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,XP_005246143.1|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,XP_006712671.1|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,XP_011547155.1|MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY,XP_011547|
16	ATG16L2	89849	Autophagy-related protein 16-2	ATG16L2	ATG16B|WDR80	human	NM_001318766.1,NM_033388.1,XM_005274376.3,XM_005274378.2,XM_006718732.2,XM_006718733.2,XM_006718734.2,XM_011545332.1,XM_011545333.1,XM_011545334.1,XR_	NP_001305695.1,NP_203746.1,XP_005274433.1,XP_005274435.1,XP_006718795.1,XP_006718796.1,XP_006718797.1,XP_011543634.1,XP_011543635.1,XP_011543636.1	NC_000011.10,NC_018922.2,NT_167190.2,NW_004929380.1	Q8NAA4,Q9H7Q5	NULL	NULL			May play a role in autophagy. {ECO:0000250}.	Hs.653186	11214971,12477932,14702039,18187620,21900206,23266558,23439083,23563314,23850713,24406150,25720964,26673895	15		NP_001305695.1|MAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,NP_203746.1|MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,XP_005274433.1|MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHWYLNLSHPWSVTIF,XP_005274435.1|MAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,XP_006718795.1|MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFSFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,XP_006718796.1|MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLQPPGHWRG,XP_006718797.1|MPQGSWRLPPEKDLLNALLTPTHLTPVLRRGEVTQLGEPLSSDTRSSLCVWLPDFLPGLRMCCSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,XP_011543634.1|MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISESASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,XP_011543635.1|MAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ,XP_011543636.1|MAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ
16	Atg16l1	77040		Atg16l1	1500009K01Rik|Apg16l|Atg16l|WDR30	mouse	NM_001205391.1,NM_001205392.1,NM_029846.4,XM_006529950.2,XR_387198.2	NP_001192320.1,NP_001192321.1,NP_084122.2,XP_006530013.1	AC_000023.1,NC_000067.6,NT_078297.7,NW_001030662.1	G9M4M6,Q3TDQ5,Q8C0J2	Cytoplasm.  Preautophagosomal structuremembrane.	NULL				Mm.272972,Mm.456099	8889548,10349636,11042159,11076861,11217851,12466851,12477932,12665549,12904583,15449545,15489334,15761153,15782199,16141072,16141073,16602821,18321988,18448665,18799693,18849965,18849966,18946037,19139628,19269148,19382893,19783656,19898471,19926846,20602997,21220506,21267068,21677750,22082872,22167182,22258505,22520467,22715292,22740627,23392225,23658055,23954160,23973919,24089209,24089213,24162724,24238340,24384785,24550300,24553140,24563254,24591649,24821797,25308334,25485521,26195741	19		NP_001192320.1|MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDMPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQMNEAKISEYLQTISDLETNCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSDAARRRSVSSIPVPQDIMDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP,NP_001192321.1|MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDMPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQMNEAKISEYLQTISDLETNCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATRRSVSSIPVPQDIMDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP,NP_084122.2|MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDMPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQMNEAKISEYLQTISDLETNCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDIMDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP,XP_006530013.1|MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDMPNRHEISPGHDGAWNDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQMNEAKISEYLQTISDLETNCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAVSRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSDAARRRSVSSIPVPQDIMDTHPASGKDVRVPTTASYVFRH
16	Atg16l2	73683		Atg16l2	2410118P20Rik	mouse	NM_001111111.1,XM_006508225.2,XM_006508226.2,XM_006508227.2,XM_006508228.1,XM_006508230.1,XM_006508231.2,XM_011241916.1,XM_011241917.1,XM_011241918.1,	NP_001104581.1,XP_006508288.1,XP_006508289.1,XP_006508290.1,XP_006508291.1,XP_006508293.1,XP_006508294.1,XP_011240218.1,XP_011240219.1,XP_011240220.1	AC_000029.1,NC_000073.6,NT_039433.8,NW_001030877.1	G9M4M8,Q6KAU8	Cytoplasm.	NULL				Mm.275744	10349636,11042159,11076861,11217851,12466851,12477932,14610273,15449545,15747579,16141072,16141073,18799693,21677750,22008794,22082872,23563314,24550300	19		NP_001104581.1|MAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFSPDRSYALAGSSNGDLYIWDVNTGKLETSLQGPHCTAVNAVAWCFSGNHVVSVDQGRKVVLWH,XP_006508288.1|MESPGGSAPLLGLELCAAARDSAAMAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFSFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFRLFKRRPVHLGCEHRETGDQPTGTPLRLLKPPAGWMSRVRVRLPACSCCPPEVCLPSSALLLMPWLGASPGTTL,XP_006508289.1|MESPGGSAPLLGLELCAAARDSAAMAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFSFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFSPDRSYALAGSSNGDLYIWDVNTGKLETSLQGPHCTAVNAVAWCFSGNHVVSVDQGRKVVLWH,XP_006508290.1|MESPGGSAPLLGLELCAAARDSAAMAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFSPDRSYALAGSSNGDLYIWDVNTGKLETSLQGPH,XP_006508291.1|MAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFRLFKRRPVHLGCEHRETGDQPTGTPLRLLKPPAGWMSRVRVRLPACSCCPPEVCLPSSALLLMPWLGASPGTTL,XP_006508293.1|MAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFRLFKRRPVHLGCEHRETGDQPTGTPLRLLKPPAGWMSRVRVRLPACSCCPPEVCLPSSALLLMPWLGASPGTTL,XP_006508294.1|MESPGGSAPLLGLELCAAARDSAAMAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFRLFKRRPVHLGCEHRETGDQPTGTPLRLLKPPAGWMSRVRVRLPACSCCPPEVCLPSSALLLMPWLGASPGTTL,XP_011240218.1|MESPGGSAPLLGLELCAAARDSAAMAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFRLFKRRPVHLGCEHRETGDQPTGTPLHCC,XP_011240219.1|MESPGGSAPLLGLELCAAARDSAAMAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRWLQVQF,XP_011240220.1|MAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFRLFKRRPVHLGCEHRETGDQPTGTPLRLLKPPAGWMSRVRVRLPACSCCPPEVCLPSSALLLMPWLGASPGTTL
16	ATG16	855194	Autophagy protein 16		APG15|APG16|CVT11|SAP18	baker's yeast	NM_001182663.1	NP_013882.1	NC_001145.3	Q03818	Preautophagosomal structure membrane.	NULL			Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS). Recruites also ATG3 to the PAS. Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. {ECO:0000269|PubMed:10406794, ECO:0000269|PubMed:11689437, ECO:0000269|PubMed:11897782, ECO:0000269|PubMed:15569245, ECO:0000269|PubMed:17132049, ECO:0000269|PubMed:17192262, ECO:0000269|PubMed:22652539, ECO:0000269|PubMed:23064152, ECO:0000269|PubMed:8224160, ECO:0000269|PubMed:8663607}.		8849441,9169872,10406794,10688190,11283351,11689437,11897782,16554755,16874032,17012802,17192262,17986448,18701704,18719252,18997338,19793921,19889643,20093466,20421943,20489023,21232131,21987634,22768199,22842922,23064152,23238393,23549786,24586198,26061644,26067383	28	1->21,99->150	NP_013882.1|MGNFIITERKKAKEERSNPQTDSMDDLLIRRLTDRNDKEAHLNELFQDNSGAIGGNIVSHDDALLNTLAILQKELKSKEQEIRRLKEVIALKNKNTERLNDELISGTIENNVLQQKLSDLKKEHSQLVARWLKKTEKETEAMNSEIDGTK
16	spf38	2539984	Pre-mRNA-splicing factor cwf17		cwf17		NM_001023856.2	NP_596835.1	NC_003423.3	O94620	Nucleus.	NULL			Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.		11859360,11884590,15755920,16823372,18818364,21386897,22681890,24014766,24081329,24210919,24442611,24713849,24874881,24957674,25274039,26771498	33		NP_596835.1|MDKRKESESATNGHLVKRIRIQDSSLITEGSVLQRTSDLNVPNLQMFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVKNYGVLNGCKGAITDLQWSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDCIKTIEEKYPLTAVAIAQQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKPFASAQRQLQIFEGAIHGQEHNLLGVAWSRNSRFVGAGSSDKNVYVWSATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRTIFLGELN
16	VOLCADRAFT_116733	9624148				volvox	XM_002948257.1	XP_002948303.1	NW_003307552.1	D8TP71	NULL	NULL					20616280	81		XP_002948303.1|MSLVPPDFCDSSSPGPRRAGSLPASPSQLHTVPPGPFPHAAYPGLPICLSSQDPPTQAASSPAKHAQPFPHMYQMSIMGQQQHLAALDLAAAAHSPSGGALQTSPSRMLPSPNSGMPLHGAQHPYLGYDAGMQQYCSQHPQRLHPPGQQHSSVHGLVPSFPAAAGPGTGSDAVVAGNQHQNHPYNMAPYGYFPPYVQQQPLSGSPLGHHQQFLGPRTSVPYGAPFASPPRHVSSQQSPPNGGGGGGAGMGQQQGGPLRHNDTAAIGPPADGAVYGAAVQAASEGGPRGAVAREGAPAAIWVGDPNASGHNAPHGAGPAVAASPPAMAKAAPSGGVMGSPQGPTLGGFLAAAAGGNALHGAVRHVVDELRTSPLILPSDYDTPGRGSIGITGGGRSTGGAAYGSGGGGGSGEKNAAIQRYQAQIVSLERQNAELQKRLTDTQSALEAARQARQALEAKQDAMADQVAQANHGAKSRESALESARRANDALSGELRSCQDEVAALRNALAAAKDTAVQWQDRAMEVGKELEAARKKIETLGEEERRLSSENMALRKEVQQLNDVIIKGRIESAELREKLRSSQQDAARAASTAQALASRVESEHEGAAVQMTVMRNKLSELESRNSQLLYDVSGLREEVSRARQAADAAKAALAAKPAGIASEGVGSVRQQQHHHHMSGATSAGWMGLEAQQPSGNSIAPGLGLGGGSGSGAYNGASYGGPYGGNIGNGYNGVGSSVEYSGPGFGAAGFGGGGPSGSVNGGGSGTASGNGGVGGGSFSQRPPAALPPPPQPGSFPSSHSGQATISAILRDLPTDMAFSKLDPETFRNMVRAEAEAMGRGGGGGGGDGLYSAASSPLKPSYGTRHGGGGGDLGTVPSSGALDGVALLPPPPPRLAWGDGPGRDLAAAPPPPPLPDARNMWRAPPPLADEGGFGGRGGGGGGASKAPNTGAANSSYATGRGVAPLQGNGGAGGGGGSGGSPPPYAVNLVDNPYAHRRPANAVGTGGAPPGGGMGSGNGGAYNGETPYGTEETVKDMIARSKALEDKLMVLCSEKGGLEAEYARMPLGAGRSLRERNRKQVVEQRLELLNKEISSVRMQLKRLGVK
17	ATG17	851142	Autophagy-related protein 17		APG17	baker's yeast	NM_001182311.3	NP_013527.3	NC_001144.5	Q06410	Cytoplasm.  Preautophagosomal structuremembrane.	NULL			Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre- autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity. Plays particularly a role in pexophagy and nucleophagy. With ATG13, is required for ATG1 activation by autophosphorylation of 'Thr-226'. Recruits ATG9 to the pre- autophagosomal structure. Plays also a role in regulation of filamentous growth. {ECO:0000269|PubMed:10995454, ECO:0000269|PubMed:11486014, ECO:0000269|PubMed:12048214, ECO:0000269|PubMed:15743910, ECO:0000269|PubMed:15901835, ECO:0000269|PubMed:17362880, ECO:0000269|PubMed:17700056, ECO:0000269|PubMed:18077553, ECO:0000269|PubMed:18287526, ECO:0000269|PubMed:18701704, ECO:0000269|PubMed:19061865, ECO:0000269|PubMed:19223769, ECO:0000269|PubMed:19371383, ECO:0000269|PubMed:19805182, ECO:0000269|PubMed:19995911, ECO:0000269|PubMed:20439775, ECO:0000269|PubMed:20729555, ECO:0000269|PubMed:21712380, ECO:0000269|PubMed:22768199, ECO:0000269|PubMed:23169651}.		8849441,9169871,10688190,10995454,11283351,11489916,11805837,12048214,15263065,15659643,15743910,15766533,15901835,16204215,16429126,16487579,16554755,17295840,17362880,18077553,18212056,18287526,18701704,18719252,19269370,19337029,19371383,19755117,19793921,19995911,20041197,20065092,20093466,20439775,20489023,20826334,21712380,21839922,21987634,22243599,22768199,22778255,22875988,22885598,23390603,23549786,23716696,23858448,23904270,23939028,24586198,24793651,25998554,26061644,26086550,26673895	28		NP_013527.3|MNEADVTKFVNNARKTLTDAQLLCSSANLRIVDIKKKLSSWQLSISKLNFLIVGLRQQGKFLYTILKEGIGTKLIQKQWNQAVLVVLVDEMKYWQYEITSKVQRLDGIVNELSISEKDDTDPSKLGDYISRDNVNLLNDKLKEVPVIERQIENIKLQYENMVRKVNKELIDTKLTDVTQKFQSKFGIDNLMETNVAEQFSRELTDLEKDLAEIMNSLTQHFDKTLLLQDKKIDNDEREELFKVVQGDDKELYNIFKTLHEVIDDVDKTILNLGQFLQAKIKEKTELHSEVSEIINDFNRNLEYLLIFKDISNLIDSFKNSCTQDIQTTKELCEFYDNFEESYGNLVLEAKRRKDVANRMKTILKDCEKQLQNLDAQDQEERQNFIAENGTYLPETIWPGKIDDFSSLYTLNYNVKNP
18	atg-18	179246				nematode	NM_171491.3,NM_171492.4	NP_741576.1,NP_741577.1	NC_003283.11	H2KYN5,O16466	NULL	NULL				Cel.17812	9851916,12958363,16530747,17172799,17417969,17901876,21183797,21285529,21502138,21802374,21906946,21998252,22451698,22862955	5		NP_741576.1|MSATTSEENPDSINYIGFNQDSKVICVGHKDGYMFYKTADILENNTLTYEGENLTHLGLNNCLIIERLFSSALMVVISQKDPRVLHVYHFTSRNIICDHRFNKSVLTVRLNRDRIVVCLEDCIYIYNLKDMKMMHNIMDTPTNKLGVLDLTSNPGNALIAYPGSTDTGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTVIRVYSVPNGHRLFEFRRGVTRCVNIYSLCFSSDSKYLTSSSNTETVHVFKLEKTEGVDNKPEASTEGGGWFDAINKTFSAYMPSQVLQVGELMTTERSFATAKLPGAARSNQVSLVSHKNQQYVMAATSDGFVYAYRLDPEGGELDLIKQHNIGPKSDTSRASPTSTGSGGAAKSAEASNQSVPNMDDPDDFPPMSHTSG,NP_741577.1|MSATTSEENPDSINYIGFNQDSKVICVGHKDGYMFYKTADILENNTLTYEGENLTHLGLNNCLIIERLFSSALMVVISQKDPRVLHVYHFTSRNIICDHRFNKSVLTVRLNRDRIVVCLEDCIYIYNLKDMKMMHNIMDTPTNKLGVLDLTSNPGNALIAYPGSTDTGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTVIRVYSVPNGHRLFEFRRGVTRCVNIYSLCFSSDSKYLTSSSNTETVHVFKLEKTEGVDNKPEASTEGGGWFDAINKTFSAYMPSQVLQVGELMTTERSFATAKLPGAARSNQVSLVSHKNQQYVMAATSDGFVYAYRLDPEGGELDLIKQHNIGPKSDTSRASPTSTGSGGAAKSAEASISV
18	WIPI1	55062		WIPI1	ATG18|ATG18A|WIPI49	human	NM_001320772.1,NM_017983.6,NR_135470.1,NR_135471.1,XM_005257497.3,XR_934496.1	NP_001307701.1,NP_060453.3,XP_005257554.1	NC_000017.11,NC_018928.2,NG_007093.3,NT_010783.16,NW_004929407.1	B4DX63,G5EA37,Q5MNZ9	Golgi apparatus, trans-Golgi network. Endosome.	NULL				Hs.463964	12477932,14702039,15020712,15489334,15602573,16169070,17618624,19936222,20505359,20562859,21317285,21564513,24384561,24991767,25233424,25462558,26186194	15		NP_001307701.1|MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS,NP_060453.3|MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS,XP_005257554.1|MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
18	WIPI2	26100		WIPI2	ATG18B|Atg21|CGI-50|WIPI-2	human	NM_001033518.1,NM_001033519.1,NM_001033520.1,NM_001278299.1,NM_015610.3,NM_016003.3,XM_006715685.1	NP_001028690.1,NP_001028691.1,NP_001028692.1,NP_001265228.1,NP_056425.1,NP_057087.2,XP_006715748.1	NC_000007.14,NC_018918.2,NT_007819.18,NW_004929329.1	A0A024R823,Q9Y4P8	Preautophagosomal structure membrane.	NULL				Hs.122363	9847074,10810093,11076863,11230166,11256614,12477932,12853948,14702039,15489334,15489336,15602573,16169070,16381901,18029348,20505359,20562859,21044950,21145461,21564513,21575909,22456507,22939629,24954904,24991767,25147182,25233411,25233424,25416956,25462558,25578879,26186194	15		NP_001028690.1|MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_001028691.1|MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_001028692.1|MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_001265228.1|MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_056425.1|MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_057087.2|MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,XP_006715748.1|MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
18	Wipi1	52639	WD repeat domain phosphoinositide-interacting protein 1	Wipi1	4930533H01Rik|AW411817|D11Ertd498e	mouse	NM_145940.2	NP_666052.1	AC_000033.1,NC_000077.6,NT_096135.6,NW_001030434.1	Q8R3E3	Golgi apparatus, trans-Golgi network.  Endosome.	NULL			Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation- induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway. {ECO:0000269|PubMed:22275429}.	Mm.35817	10349636,10725249,10922068,11042159,11076861,11217851,12466851,12477932,15226823,15489334,15782199,16141072,16141073,21267068,24098492	19	1->20,283->307,359->400,433->446	NP_666052.1|MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTVLDIPSNPTGLCALSINHSNSYLAYPGSQSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKMEHLTDSRPEEPSTWSGYMGKMFMAATNYLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSLLSSGTTEENKENDLRPSLPPSYAATVARPSTSAASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGSQKGKTKQS
18	Wipi2	74781	WD repeat domain phosphoinositide-interacting protein 2	Wipi2	1110018O08Rik|2510001I10Rik	mouse	NM_178398.4,XM_006504752.2	NP_848485.1,XP_006504815.1	AC_000027.1,NC_000071.6,NT_039316.8,NW_001030796.1	Q80W47	Preautophagosomal structure membrane.	NULL			Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). Recruits the ATG12- ATG5-ATG16L1 complex to omegasomes, resulting in ATG8 family proteins lipidation and starvation-induced autophagy. Omegasomes are derived from ER and serve as intermediates for genesis of isolation membrane (also called preautophagosome) from ER cisternae membranes. {ECO:0000269|PubMed:23051912, ECO:0000269|PubMed:23291478, ECO:0000269|PubMed:24954904}.	Mm.29432	8889548,10349636,10922068,11042159,11076861,11217851,12466851,12477932,12904583,14610273,15489334,15782199,16141072,16141073,18799693,21267068,26496610	19		NP_848485.1|MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEAVREKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,XP_006504815.1|MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEAVREKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
18	ATG18	850577	Autophagy-related protein 18 {ECO:0000303|PubMed:14536056}		AUT10|CVT18|NMR1|SVP1	baker's yeast	NM_001179986.1	NP_444297.1	NC_001138.5	P43601	Preautophagosomal structure membrane.	NULL			The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). May negatively regulate FAB1 activity by sequestering or masking VAC7 from FAB1. Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication. With ATG2, protects ATG8 from ATG4-mediated cleavage. {ECO:0000269|PubMed:11470404, ECO:0000269|PubMed:11536337, ECO:0000269|PubMed:11707261, ECO:0000269|PubMed:11739783, ECO:0000269|PubMed:14723849, ECO:0000269|PubMed:15155809, ECO:0000269|PubMed:15194695, ECO:0000269|PubMed:16876790, ECO:0000269|PubMed:17699591, ECO:0000269|PubMed:18586673, ECO:0000269|PubMed:18769150, ECO:0000269|PubMed:19037259, ECO:0000269|PubMed:20154084, ECO:0000269|PubMed:22108003, ECO:0000269|PubMed:22728243, ECO:0000269|PubMed:22787281, ECO:0000269|PubMed:24905091}.		7670463,8849441,11536337,11707261,11739783,11805826,11805837,14723849,15103325,15372071,16319894,16554755,16876790,17295840,17699591,17875934,18467557,18497569,18586673,18701704,18769150,18829864,19037259,19841731,20093466,20154084,20526336,21036361,21070969,21887408,21987634,22728243,22768199,22842922,22851171,23230146,23332755,23549786,23904270,24440502,24586198,25803831,26061644	28	1->13,137->228,320->377,435->463	NP_444297.1|MSDSSPTINFINFNQTGTCISLGTSKGFKIFNCEPFGKFYSEDSGGYAIVEMLFSTSLLALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQIYIYDINTMRLLHTIETNPNPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQDAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMAISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTYATRIYSISFSEDSQYLAVTGSSKTVHIFKLGHSMSNNKLDSDDSNMEEAAADDSSLDTTSIDALSDEENPTRLAREPYVDASRKTMGRMIRYSSQKLSRRAARTLGQIFPIKVTSLLESSRHFASLKLPVETNSHVMTISSIGSPIDIDTSEYPELFETGNSASTESYHEPVMKMVPIRVVSSDGYLYNFVMDPERGGDCLILSQYSILMD
18	mug179	2543297	Autophagy-related protein 21		atg18b		NM_001019272.2	NP_593843.1	NC_003424.3	Q9P6N1	Cytoplasm.  Golgi apparatus, Golgi stackmembrane.	NULL			Required for cytoplasm to vacuole transport (Cvt) vesicles formation and autophagy (By similarity). Has a role in sporulation. {ECO:0000250, ECO:0000269|PubMed:16303567}.		11859360,16823372,19778961,23050226,23950735	33		NP_593843.1|MPSIILYCSWNQDRGFLSIGSENGYQVYRSNPFTLCFSKKANGASICEMLYESSLLAFVNISPESTRLLKLVDIKRDIVLCRIFYPSPVLSVRFTWNRLVVLIKGSIYVYNLKNMELINTLNTSKGNVIAFAVHENYVAYNSPTNPGDIYLASLDTAIPVTLIHCHSSAVQVVDFHPRGHLIATASAKGTVIRVITTSDGELVTELRRGYIPASIVSISFHPVEPFLACASENGTIHVFKISKQPSDPNSSPTSSVTVSSSWSKYLTSNVAKVWDTRKEFATAKIPEASFYGKIIFSSSGPHIQVASYSGHYYRFAVNLKNGGNCALLERYIFDD
18	SPAC458.06	2543338	SVP1-like protein 2				NM_001020128.2	NP_594700.1	NC_003424.3	Q9P3W2	Vacuole membrane.	NULL			Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways. {ECO:0000250}.		11859360,16823372,18818364,19778961,22681890,23950735	33		NP_594700.1|MSTINTVSLNQDASCMSVALDTGYKIFQINPLKLRAQRQFNDGGLSIVKMLFRSNVLLLVGGGGNPKYAPNKLIVWDDVKERPVKELELNFEIKGICFDGKLLAIATASKLFLYQFGNNLKLQRCLDTQNPKGLCAMVTTVEKTAIVFPSRKVGQLQILFLFKDHMNTSIVPAHDSEISCLGISKTGSKIASSSTNGTLIRIWNSETGEKICEFRRGYQHTAVCQLAFSPDELLLACASKKETLHIFSLHGSPNTIRQLTSEEPYEEASEFKSSTTEPRQTHWKRKLLKLIDSGKRAHWRIQLYQSNPVLLHWLDEMTILICYKDAAYQKLKLTIEESSKSVEHANQHVCFHYDYTLEADGSLC
18	VOLCADRAFT_103431	9620302				volvox	XM_002947293.1	XP_002947339.1	NW_003307549.1	D8TLT4	NULL	NULL				Vca.1513	20616280	81		XP_002947339.1|MALSSKSGVLHVSFNQDCSCVALGSQQGVHIYNVDTHKLCYRYAIGAVSIVEMLFCTSLVGFVGAGEQPALTPRKLTVMNTSASRVIQELSYPISVLAVRMNRQRLVVVTSQAVHVYCLSKLACLRVIETENNPGGCCALTCCHEPNLLALPSSSRTGTVRIYDLTQEGQGNVLSEVQAHQSPVVAAFKDTFWSVLRLTVLAWSSDGGLLATATAKGTLIRVHRMPRAARSHSFRRGATSATIQSLAFGPVGLPVQLLVAASSHGTVHVFRLEDPEPCGGGLLPRPGGSVAGGLLSAVVKYSSQMVGDLVEPARNIATIRLPRSVGIAICAFRSQPGNCYCYSASPELATAAVATTATATSPAEAIHPNSRVTVAGPPGPPGCDPGSAAAGAAVVQAELGSGDRGEAKSACGGRSAWGGTTGGSGGGWGGVRCGTAGGGDAGAGVCGGGRWQEGLLYEYTLTDLLSQQGPKCNLDGEWSMVIEVSYVGWYEGSVRPQDVCTLPTWVGRMPVGGVLWPSGSAVRVKATQQGHQLQQRTGSVQSPIPSLSYTSFREKLAAMCSAVGIKRGIMPHSMRIGGNSAAAARGVSEEARKAHGRWKTDAMVQLYTRMEDDAALETTRNLGLA
18	VOLCADRAFT_42684	9614600				volvox	XM_002955830.1	XP_002955876.1	NW_003307598.1	D8UAY9	NULL	NULL					20616280	81		XP_002955876.1|EEILHVGFNQDYGCFACGTTNGFRVYNCEPFKETFCRGFNNGGIGIVEMLFRCNILAIVGGGAAPRYPPTKVMIWDDHQGKCIGEMTFRSQVRAVRLRRDRIVVALEHKVLVYNFADLKLLHQTETCANPRGLVAISSTAAMSSASDNTVLACPGLHTGQVRIELYDRRQTKFIPAHNNALSCLVLSMDGKRLVTASEKGTLVRVWNTADGQLLQELRRGADPAHIYSLALSRDCEWLALTSDKGTVHVFAPLLCDDGAETPTASSPSSVQGYVPAIPLPKYFNSEWSFAQFRIHDEPAASAGHPLPSIVGFGAEPNTVLVVTAGGSFYKVAFDPAKGGQCSQLSYCKFLE
18	VOLCADRAFT_95446	9625043				volvox	XM_002954547.1	XP_002954593.1	NW_003307587.1	D8U7H0	NULL	NULL					20616280	81		XP_002954593.1|MARPSSLPGNPVTGLRDDFFGRPDMLNNSVTQTRMPTKCNSGLLALKVPDPPQFAPSAVCAISADGKIAAVGGRDIELFLWDVDTGDLLSKIRGHDIFWVGSHDNAFFITCQEDGKVVLWDRGTMRTTLTLGEVADGITCCHIAQDNDFVVVGSAKGNVYSWDTDTGTVAHMYEAGHKGPVQFAQVYSLPSYGRCVVSCGAKDHTVVVWDLLSGEPRALIEIKELEHAKNLKYDVTRDGARVVVWCTDSVPFPNLVVVDIMSQNKISVYCHEGLVRQAVFTPNGDRIISSGNDNRLQVWDTFSLENLVTMSGHEGSVLCCAVNETATRVVSGGEDCSVRLWSLDDGKQLLCFQAQDEPIKQVQFASSGQKILSCDVTGRVYVWSMHAEFLTNLMRRYADNISACAMSNDMKLCLVGCNNGRVMLWDVERRESVWEYTHHTGRVEAVAFNSMRDMCATAGADGRIVLLFSDSGKQANSFLGAEEPMMTVQFSPDDERIAGCAADGKLYLYTTAGSTRKPKAVLRSSVARISNHVWSPNSKLVAGACSDGTMMVWNASSGGIHSVLEGAAVGATCCCFDLIGKLLAVGTVLGTTLMYNLETSEMLVELKGNASPVREVVFNQETSQLTTMCSRQACVWDVSSATKIRVFDFVMDKAGDFKSPPHPYRWAVAHNSTVLFDHESEALVLDMLTIDDPLLRSYYLSDVQTIASGFNHRKLLVWSAAGSSAPDKFHTTHDAITSTHFSNDDRLVVMGTQDGNVVVYDVVHGETVEIIVGHQNGPCRCVKLSADNREVLSCGADSKVVLWDWRKRSPLRIYSGHFISIGCCDMSMQGNRVVSGDNHGMICVWEKDSGNPVQTLPLAHSKAVLSVTISADGSTIASVGADDKARGSTRVSIWNVDIGIELVSLTAAVESHPLYCSFSPDGNKLAVTESNGNVMVWNVAAGCQWYMIYQAHKGKVTGCSWSADCRKFTTCGTDSVAAIWDAESGAPLFKFNLKAGPLTSCSVSPSGLYVAAGSTTGTLSVSNLATAARNTPEPSFLFHWLATHDLKAANFLYLRLLAMYPFLANVQDAQGWSIALHALSRGNAEVSAIVMDALSNECGVLGLISAVPFSVATRIKFHNQPDEPAGLFGGGGGGGGAGARPTSAWAGGGDGGNRSIRPRTAAALRSASMAVGAEGNKSMRRASLAFLKPDDDDGQLLPDMRQGSNLRDVLVQKSKASFSQQLKKVAVEMVTETRDQDHMALIQNNAVALALNSKSSECVQAVLDAAAANKVSWGSYHAITDMMPSLALRYPIMCYHFLAALDLRNLGDLEVPVAVLKGLDRSVIRTAPIFTNVKNLWQGHLKLHEVKFGPQPYAHVKASMVRLPYACSIGRDSLLQTLVESDVPVKVYGTPTLRAIIKHKWRLYARRKLLLRSLVYVFYVIMFTVTGILFSLEDHTLSMSGYWKTSQGKAHFIIDGYIFAQTAWYAWTELTQMYAIGLSMYFRSYWNTFDSLMICLVLLIPPLHVVRLSDNEGGALGPLIAFAMIMVWFKSLFYGLAFEPFGPIVNMVFQISRAIRQFMVMLFMCCCAFGVSLMVLSQYSTTSYLGLPDQYSRDGGQDFGRTLFTMWRAVLGQFDVSWVWGSAWQELSILFFSGFMFAVQILLLNMLIALMREVYNRVKNTEEDVFLKGRATLIVEVETLMARKQLERYANMPPYVHLLTPVKRNDVRDRSGLEARLEKMEQMLMKLQDALDQGLVGPRGAPVAALPPAGGPVGHLVGGDGHGGDGSNINTAALTQEQLNLIQLQAGKLKEMEDQFPAVLRQLDRVQRSVNNQELRLEGVVTVLRDIENLLRNQQPVVIHQENRPMPRRGSVLTEAELEAEVKRLLGKGDEKL
19	ATG19	854072	Autophagy-related protein 19		CVT19	baker's yeast	NM_001183336.1	NP_014559.1	NC_001147.6	P35193	Preautophagosomal structure membrane.	NULL			Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as APE4, LAP3, LAP4 and AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole. Involved in the organization of the preautophagosomal structure (PAS). ATG19 association with cargo protein is required to localize ATG11 to the PAS. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates, and is essential for the survival of cells subjected to severe ER stress. Plays also a role in regulation of filamentous growth. {ECO:0000269|PubMed:11382752, ECO:0000269|PubMed:11430817, ECO:0000269|PubMed:12479807, ECO:0000269|PubMed:12479808, ECO:0000269|PubMed:15138258, ECO:0000269|PubMed:15659643, ECO:0000269|PubMed:15801807, ECO:0000269|PubMed:16186126, ECO:0000269|PubMed:17132049, ECO:0000269|PubMed:17192412, ECO:0000269|PubMed:17238920, ECO:0000269|PubMed:17700056, ECO:0000269|PubMed:19021777, ECO:0000269|PubMed:19061865, ECO:0000269|PubMed:20659891, ECO:0000269|PubMed:21228276}.		8849441,9169874,10688190,11283351,11382752,11430817,11675395,11805837,12479807,12479808,15138258,15659643,16186126,16319894,17192412,17238920,18497569,18719252,19021777,19398890,19619494,19840948,20093466,20489023,20615880,20639194,20659891,21228276,21343297,21460040,21839922,22123825,23390603,23801757,24586198,24705553,24968893,25009170,25287303,26673895	28	1->17,108->194,230->289,359->415	NP_014559.1|MNNSKTNQQMNTSMGYPLTVYDECNKFQLIVPTLDANIMLWCIGQLSLLNDSNGCKHLFWQPNDKSNVRILLNNYDYGHLFKYLQCQRKCSVYIGEGTLKKYNLTISTSFDNFLDLTPSEEKESLCREDAHEDPVSPKAGSEEEISPNSTSNVVVSRECLDNFMKQLLKLEESLNKLELEQKVTNKEPNHRISGTIDIPEDRSELVNFFTELKTVKQLEDVFQRYHDYERLSQECDSKTEIASDHSKKETKIEVEPPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFTDAGDKPTTQIIDMGPHEIGIKEYKEYRYFPYALDLEAGSTIEIENQYGEVIFLGKYGSSPMINLRPPSRLSAESLQASQEPFYSFQIDTLPELDDSSIISTSISLSYDGDDNEKALTWEEL
20	ATG20	851445	Autophagy-related protein 20		CVT20|SNX42	baker's yeast	NM_001180172.1	NP_010170.1	NC_001136.10	Q07528	Endosome membrane.	NULL			Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy. Also involved in endoplasmic reticulum- specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Functions in protein retrieval from the endocytic pathway. Required for proper sorting of the v-SNARE protein SNC1. {ECO:0000269|PubMed:12048214, ECO:0000269|PubMed:12554655, ECO:0000269|PubMed:15901835, ECO:0000269|PubMed:16138904, ECO:0000269|PubMed:17132049, ECO:0000269|PubMed:19793921, ECO:0000269|PubMed:20861302}.		8849441,9169867,10688190,11557775,11805837,12048214,12554655,12876220,14574415,15263065,15659643,16319894,16429126,17634282,18467557,18497569,18719252,19591838,19793921,19840948,20065092,20093466,20861302,21127052,21987634,22615397,22875988,23209445,24586198,26493364	28	1->144,302->448,487->605,638->640	NP_010170.1|MSDLNDVQENAKLNSETRNTGKAEPPHGTTEYVAEAEISKNGVGSPKKSPKKGKVGKGDNNKVETELVHTALLEKDNPFMEEGPTGFTKSALLEIPGMRSHNLKNPNEDYEDDSEGLLPLNQESNAETCRTSLSGSINSMNGETSASEEPSVSNRKKSARIHILEAKRVSEGQGRAYIAYVIQFENSTVQRRYSDFESLRSILIRLFPMTLIPPIPEKQSIKNYGKSITGSSSKYLLPSEGSGSVDLSLSVIHASVNNSDEKLIRHRIRMLTEFLNKLLTNEEITKTSIITDFLDPNNHNWHEFVNSSSTFSSLPKSILQCNPLDPTNTTRIHAMLPIPGSSSQLLLNKESNDKKMDKERSKSFTNIEQDYKQYENLLDNGIYKYNRRTTKTYHDLKSDYNEIGEVFAQFAHEQAQVGELAEQLSYLSNAFSGSSISLEKLVGRLYYNINEPLNESVHMATSARELIKYRKLKYLQNEMIKKSLNSKRAQLEKLEAQNNEYKDVDKIIDNEMSKSHTINLERPNNNTGSGGKSYGGKLFNGFNKLASMVKDSVKYQETDPHTASINLKKEIEQLSESLEVTENDLEVISKVIKNDQLPKFSKEREVDLSEILKHYSRYMRNYARQNLEIWKEVKRHQDFA
20	VOLCADRAFT_69645	9628060				volvox	XM_002958537.1	XP_002958583.1	NW_003307641.1	D8UIV1	NULL	NULL					20616280	81		XP_002958583.1|MLFDYLCSALDFLPACFKVADPVKQGEGVAAYVSYKVRTKTTHVNYDAPFNEVTRRFRDFAWLHDKLVEKNKGHIVPPLPEKSAVQKYQMATDFIEQRRRALQVFLNRVASHPILKDSRELQTFLQANDEQWMLETAKWQAETSAQHRPVSAAAQWFKSLQHSAQSLVSGRADDMQEDAEYIKIRDYVNSLENHLTEAHRQAGRLLRKEADLGSALAEFAAAAEQLGKQDSEGPMRVAFGCLFTRANEVAALSRARSEAIAVEFAAPLKEFARTIKSVQVAMADRAAALSTYSQAKSDLDSKKVRLAKLRGTPGLKEDKLAETERDVNEADQRLRNAKLGYETIRDTMREELNRFQKERAAEMSAVLRDFALAQAHHTAEQAKAWGELLRDLQHAAVGGS
20	VOLCADRAFT_96778	9614817				volvox	XM_002955784.1	XP_002955830.1	NW_003307598.1	D8UB11	NULL	NULL					20616280	81		XP_002955830.1|MADNLGPLGRGRSKDPLDELGGLVGQTLNLFDGQAAAKGPEQLVDVYGATARATAATDNVIAQSMDLDLLGTSSTAQVAPGPLARSNTFGQEAEIPLFNDEVQIGFTHVVEEVQSPSSSPQNEPKPIESRSEVGPSGYHLVSDGPSTSTGEPNTGHLNEPPLIRVWIREPERVEGTNKLGMRTTYFTYLVRTESQLPGLRTDGSEVRRRFSEFDALHKVVKLQYRGYIIPPLPEKSFIEAKLAHEDFLRLRRADLQASIAFLRGIAQHPVLRESEALKLFLLQPGELQYNPAWTALLHSVGGSMESSEGTARLLTTQGAATATSKAVAGLNSLVSWVRHNVTSSKRELDEEEQQLRHAKELMRDLERLLQLCCESARIMCSHMDSLGADLYELGRNMGMLSKWEETLRANVGSYTEAGFSASKRAAHCKQLSFASARQHTVWKTASVKTAASLVALHDYYIVMPEAVAALEERERCLDQIQALEAELMAKHADLNKTTGGSKAASSNRDRRAYTLTNTVDRLEEQLKVCRDNYVLIKRRNMEELRRLHLTREKDFHEMMASFSALQAQLLQASADMWRTTARQFAGEAVTPAGSAGGPQEQDDD
21	WIPI1	55062		WIPI1	ATG18|ATG18A|WIPI49	human	NM_001320772.1,NM_017983.6,NR_135470.1,NR_135471.1,XM_005257497.3,XR_934496.1	NP_001307701.1,NP_060453.3,XP_005257554.1	NC_000017.11,NC_018928.2,NG_007093.3,NT_010783.16,NW_004929407.1	B4DX63,G5EA37,Q5MNZ9	Golgi apparatus, trans-Golgi network. Endosome.	NULL				Hs.463964	12477932,14702039,15020712,15489334,15602573,16169070,17618624,19936222,20505359,20562859,21317285,21564513,24384561,24991767,25233424,25462558,26186194	15		NP_001307701.1|MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS,NP_060453.3|MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS,XP_005257554.1|MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
21	WIPI2	26100		WIPI2	ATG18B|Atg21|CGI-50|WIPI-2	human	NM_001033518.1,NM_001033519.1,NM_001033520.1,NM_001278299.1,NM_015610.3,NM_016003.3,XM_006715685.1	NP_001028690.1,NP_001028691.1,NP_001028692.1,NP_001265228.1,NP_056425.1,NP_057087.2,XP_006715748.1	NC_000007.14,NC_018918.2,NT_007819.18,NW_004929329.1	A0A024R823,Q9Y4P8	Preautophagosomal structure membrane.	NULL				Hs.122363	9847074,10810093,11076863,11230166,11256614,12477932,12853948,14702039,15489334,15489336,15602573,16169070,16381901,18029348,20505359,20562859,21044950,21145461,21564513,21575909,22456507,22939629,24954904,24991767,25147182,25233411,25233424,25416956,25462558,25578879,26186194	15		NP_001028690.1|MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_001028691.1|MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_001028692.1|MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_001265228.1|MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_056425.1|MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,NP_057087.2|MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,XP_006715748.1|MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
21	Wipi1	52639	WD repeat domain phosphoinositide-interacting protein 1	Wipi1	4930533H01Rik|AW411817|D11Ertd498e	mouse	NM_145940.2	NP_666052.1	AC_000033.1,NC_000077.6,NT_096135.6,NW_001030434.1	Q8R3E3	Golgi apparatus, trans-Golgi network.  Endosome.	NULL			Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation- induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway. {ECO:0000269|PubMed:22275429}.	Mm.35817	10349636,10725249,10922068,11042159,11076861,11217851,12466851,12477932,15226823,15489334,15782199,16141072,16141073,21267068,24098492	19	1->20,283->307,359->400,433->446	NP_666052.1|MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTVLDIPSNPTGLCALSINHSNSYLAYPGSQSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKMEHLTDSRPEEPSTWSGYMGKMFMAATNYLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSLLSSGTTEENKENDLRPSLPPSYAATVARPSTSAASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGSQKGKTKQS
21	Wipi2	74781	WD repeat domain phosphoinositide-interacting protein 2	Wipi2	1110018O08Rik|2510001I10Rik	mouse	NM_178398.4,XM_006504752.2	NP_848485.1,XP_006504815.1	AC_000027.1,NC_000071.6,NT_039316.8,NW_001030796.1	Q80W47	Preautophagosomal structure membrane.	NULL			Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). Recruits the ATG12- ATG5-ATG16L1 complex to omegasomes, resulting in ATG8 family proteins lipidation and starvation-induced autophagy. Omegasomes are derived from ER and serve as intermediates for genesis of isolation membrane (also called preautophagosome) from ER cisternae membranes. {ECO:0000269|PubMed:23051912, ECO:0000269|PubMed:23291478, ECO:0000269|PubMed:24954904}.	Mm.29432	8889548,10349636,10922068,11042159,11076861,11217851,12466851,12477932,12904583,14610273,15489334,15782199,16141072,16141073,18799693,21267068,26496610	19		NP_848485.1|MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEAVREKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD,XP_006504815.1|MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSASIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLEAVREKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLTTIQKIPRLLVGASDGYLYMYNLDPQEGGECALMRQHRLDGSMETTSEIVDSASHDCPLATQTYGTAAAKGAYVPSSPTRLGKGQDANLEAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
21	ATG21	856004	Autophagy-related protein 21		HSV1|MAI1	baker's yeast	NM_001183914.1	NP_015225.1	NC_001148.4	Q02887	Cytoplasm.  Vacuole.	NULL			Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy. Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure. Protects ATG8 from ARG4- mediated cleavage. Essential for maturation of proaminopeptidase I. {ECO:0000269|PubMed:11536337, ECO:0000269|PubMed:11852075, ECO:0000269|PubMed:15155809, ECO:0000269|PubMed:15194695, ECO:0000269|PubMed:16876790, ECO:0000269|PubMed:18769150, ECO:0000269|PubMed:19793921, ECO:0000269|PubMed:20154084, ECO:0000269|PubMed:22108003}.		8849441,9169875,11536337,11852075,15103325,15155809,15194695,16306222,16319894,16876790,18458063,18701704,18719252,18769150,19547744,19793921,19840948,19841731,20093466,20154084,20526336,20861302,21196517,21490951,21987634,22282571,23332755,23390603,24586198,25279700,25691244	28	38->127,195->238,491->496	NP_015225.1|MKVLQFNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGSRDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRGQGLNKGKKLKIVNTKRKCTICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTGTLEGDSANLNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSPKKNKPNSEALYDVVIYDTLNVTPVNYLNSVHKGNVACLAVSHDGKLLATASDKGTIIRVFHTGVDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNGHWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFSKKIKSSIPNQNLSRNFAYITVNESNRSCLGFPDEFPNQVYIASDDGTFSIYSIPSKPGECVLTKNNKFT
22	ATG22	850319	Autophagy-related protein 22		AUT4	baker's yeast	NM_001178683.1	NP_009892.1	NC_001135.5	P25568	Vacuole membrane.	NULL			Vacuolar effluxer which mediate the efflux of leucine and other amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation. {ECO:0000269|PubMed:11058089, ECO:0000269|PubMed:17021250, ECO:0000269|PubMed:8663607}.		1574125,8849441,12192589,16093310,17021250,20093466,21987634,22282571,24586198	28	1->22,65->94,183->213,265->318,445->483,507->528	NP_009892.1|MSYGTINDMNESVTNYRIKKAQNNIKGWYAYSFSSEPFVVSAVSTYIPLLLQQFASINGVKVHDHSIPCLSETGSDSDKCVLGLFNNRIFVDTSSFALYVFSLSVLFQTIIVISVSGIVDLWGSVKFKGRILVWFGIVGALSTVAISKLNDTQIYSLAGLYIVANGCFGVINVVGNSLLPIFVKDSLKCQSQGAYEPDKVDSLTTVISGRGASLGYSSALIVQIVSMFLVASKKGSKQDVQVAVLFVGIWWFVWQLPMIWLIDDVTIPIRVDDSTLASARSPYPGEQDALGQLNWKNYLSYGWVSLFESFKHARLLKDVMIFLIAWFIISDSITTINSTAVLFSKAELHMSTLNLIMISVLTVVNAMLGAFMIPQFLATKFRWTSSQTLMYIIIWASFIPFYGILGFFFNAFGLKHKFEMFLLAIWYGLSLGGLSAVSRSVFSLIVPPGKESTFFSMFSITDKGSSILGPFLVGLLTDKTHNIRYSFYFFFLLLMLSLPVLNCLDVKRGRREAEELSQVLPESERRLD
23	ATG23	851151	Autophagy-related protein 23		CVT23	baker's yeast	NM_001182319.1	NP_013535.1	NC_001144.5	Q06671	Cytoplasm.  Preautophagosomal structuremembrane.	NULL			Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9. Plays also a role in regulation of filamentous growth. {ECO:0000269|PubMed:14504273, ECO:0000269|PubMed:14723849, ECO:0000269|PubMed:14734026, ECO:0000269|PubMed:17426440, ECO:0000269|PubMed:17700056}.		8849441,9169871,14504273,14734026,17135291,17426440,18497569,18829864,20093466,21232131,22271760,22768199,22875988,23904270,24586198,25385507,25631054,26673895	28	1->38,99->109,144->163,207->453	NP_013535.1|MELNQVLEKKEQILQYLGTLVGLHEKALSDVNSASQVTSIRKDITICLNDLCRINDLLVSHDGLLKREIGSLLRDKQELLELNEREQLLWKERKSWHIKQETDAAPADYVIDKDAIITISSHHRTSLNKYIESVGAENTILSNTDDSDAMIEEVQNAESSADQMIRNYKLLQLSHKQAKSEIIRLETLLRDFKKDNKFIEEELKRQSGRIRSEMGNIDFHLSKIEESKHQLMKRIGFESPLTQEKSLSEKIFNLRLSSADEDYNERQTINMKNFVHMKDLIELKIEDLQEQLMRNKNESSTVLTQRELWLDCQKKVGDLESKLITKLRSSSNSKIPPNEMSEMINSTIQYLNNLLDSSDEKLTTTLISNERDVLSKACEELHSESTTAQDGSSALPSKPIDIHKSHKGSNASSNLKQPSTPSFLVASKSPPKIGISESVVNANKNDAISKKVE
24	SNX4	853416	Sorting nexin-4		ATG24|CVT13	baker's yeast	NM_001181470.1	NP_012498.1	NC_001142.9	P47057	Cytoplasm.  Membrane.	NULL			Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells (By similarity). Involved in retrieval of late-Golgi SNAREs from post- Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy. Involved in proper sorting of the v-SNARE protein SNC1. {ECO:0000250, ECO:0000269|PubMed:12048214, ECO:0000269|PubMed:12554655, ECO:0000269|PubMed:15800066, ECO:0000269|PubMed:17420293, ECO:0000269|PubMed:18818209, ECO:0000269|PubMed:19793921, ECO:0000269|PubMed:20729555, ECO:0000269|PubMed:20861302, ECO:0000269|PubMed:21429936, ECO:0000269|PubMed:8663607}.		8641269,8849441,10688190,11283351,11557775,12048214,12554655,14764870,15263065,16429126,16452633,16554755,17101785,17420293,18467557,18497569,18701704,18719252,19591838,19793921,19840948,20065092,20093466,20826334,20861302,21196517,21490951,21880895,21987634,22384331,22615397,22875988,23332755,23409723,23893744,23986483,24470217,24586198,24700328,25026036,26493364	28		NP_012498.1|MTDKGKNDLTSKAKDKARGNPEKPPYWFEIIVSDPQKRTGDPGSSSGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDAFMNAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQELQELVTGENEELAAKLKIFNEGVTQLSYGLQDLTKYLDYEYIVDLKDLEHYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGINQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGSLADHHIEFYERILEAWEKVDDSL
26	ATG26	850886	Sterol 3-beta-glucosyltransferase		UGT51	baker's yeast	NM_001182076.1	NP_013290.1	NC_001144.5	Q06321	Cytoplasm. Membrane.	NULL			May be involved in decane metabolism (By similarity). Involved in the biosynthesis of sterol glucoside. Not involved in autophagy-related pathways. {ECO:0000250, ECO:0000269|PubMed:10224056, ECO:0000269|PubMed:17012830}.		8849441,9169871,10224056,11805826,14562095,16429126,18245329,18756268,19536198,19840948,20065090,20093466,21623372,21987634,22199229,22282571,23222640,24586198,26493364	28	1->191,334->575,677->743,1110->1198	NP_013290.1|MPITQIISASDSEAGPKPSISLVPDKPSEPETSPRHHRLSRSLSKFKRWRGRSNSSLSMGSSEQQELQDSPNEARSDDDENGYNNDNADDLAKSKYMMKSIAGLLTTASVYAGMNNAQEMNVLSQVDSEESDSSDSFQENIGRNEVKSKKENLKTKSHPEVPRLDKRKPTLFDFSITREKLSKDNVAKLRQRFCLDEQEPFLNDFPAWLLKDVLVQGHIFITTKHFLFFAYLPKNPRSVKMSGNLNIRTKLIRSTRYWCVLKNHLFSMYTSSTELYFPVLTIDLREVQKIETQKHTLNGSATKTFKLYTDESTFKFNADSEFSAKSWVNALKKEQFAAQNSENNSISLKIPLPNIIEIDDQPIVNKALTLRLRALESSQTYAIDDFMFVFMDGSGSQVKESLGEQLAILQKSGVNTLYYDIPAKKSKSSFGKETPATVEQKNNGEDSKYLNVPTSAVPSSENGKKSRFRFRERSNSWFRRAKPLEDSQVEDVEEIYKDAANDIDSSVHSTIHIHEQEDSQEQTVAWKPSHLKNFAEMWAAKPIHYRNKFIPFQKDDTYLIKETEEVSANERFRYHFKFNKEKSLISTYYTYLNRNVPVYGKIYVSNDTVCFRSLLPGSNTYMVLPLVDVETCYKEKGFRFGYFVLVIVIHGHEELFFEFSTEVARDDIERILLKLLDNIYASSAEGSNISSASLGDVQHNPDSAKLKLFEDKINAEGFEVPLMIDENPHYKTSIKPNKSYKFGLLTIGSRGDVQPYIALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAGNPVELMSLMVENESMNVKMLREASSKFRGWIDALLQTSWEVCNRRKFDILIESPSAMVGIHITEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKGISGQVNKWRVETLGLGKTNLFLLQQNNVPFLYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFKPPAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVYCILNKGWSERLGDKAAKKTEVDLPRNILNIGNVPHDWLFPQVDAAVHHGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAGLIKKKISKEDGIKTAISAIYNELEYARSVTLSRVKTPRKKEENVDATKLTPAETTDEGWTMI
26	VOLCADRAFT_104846	9618262				volvox	XM_002950793.1	XP_002950839.1	NW_003307563.1	D8TWH3	NULL	NULL					20616280	81		XP_002950839.1|MTVHLDRVSRLYTQPTYNPGRQVGPIKLQPLPGRGRGLVADRDIPAAEAVLLSEAVGGVLRGPPGAELRPRQLAEHLERLQRAGSGSGSGGGGDGDGVGLGPPDRVRLRLLYDGSPPDSPRSLRNRGASLEADFLKLEDKLRRAAEAPKKAKGKGFGAPAAAGAAAAAGAVGQTDYKGSVDAASLSGAPLQPDELLRTALYNSWGHTAGELGATALRGEVSGAIIGESKRWFELLWYFALVSAVQDISRGAEVTTSYLGELALAPLERRREWLRGAYGFECECDRCTAEASIPPPVTAAVAAAYQSAQALKTKTEGEAAAAGGGGWDLEASSVRQLGPAVTAAVEQLEAAMDSAGLPARTRSWLRASAYTAYYARAALRDVPGGSEVGTGGGGGGGGDEGCGSVLFGRGGDASRSPVPYSDPAIPAELAEVISSVASGTDLHLYLTLEALSRSAESFPRDDPRVAEATRICLRAHILRYGRTSDTVLRELLQARSTYPHYLGRVDCSASAPSGPAAQHQEQQQQDGERQQPLFANNPVFYAGVMVRGHKGDLVRLFELPPTEGRMYIFDHYVCFYSAVFGFAKKRRMPTRTIKAVRKRKHLGFPNSLEIETDDYKEFFTSFLSREEAYQLINKQLQEAKRSGLESGSSRVRRSTDNGSFFNGAGNGTIHEQSSPQSASRGGTLDGGGGRRGGGGPHGGCGSGGGAARGGLNGERSLLTRHSGSLGDDDNDDEEDSGSVWVMEPRPAPAVAAGSRHVLHTTLPGSPREFFDVVLADSAPFFEDFLDSQGNRRINLTSWKRHPQLGYVRDMNFTAPIKGAFGNWGVSHTACFQSQRFCLYEDEHIVFESSQTMTDIPYGDCFTVDQRWDIRREVFVSEGGGADTGDRATISFDLHVRVPFTSRCLFKSVIESGSVKQVQDTYAQFVEQLRPFLEERLLSRNTLNMTMVHQQDNLPPPQLSQTPRLNRGGGGMGSLAARSTQMTRSVQLQRTASHLTSRTPGRHVTGSAAFESADFGEGGVGGGTAAQQLRQSFHLGGGDSRGGGNINGEHSVARLLRSLGRRLAEGARGVFESGVDVVLNLSQCRTTPQMRFLIALVLAMFLANAVCMLGYLWHGWSSSSAASVAGGGGSGGGGGAVALDGIFFGPLLPDGGAAAVMSDLSAALGAAAGTGGSGGGAGGGGGGGVSYWVQRMALLQQEIQLLQGRMEILSREVSVVMVQLTKAAGSAAAAAATGGADPAAAAAATVAGGAFSAAAGES
26	VOLCADRAFT_107296	9619844				volvox	XM_002956542.1	XP_002956588.1	NW_003307605.1	D8UD22	NULL	NULL					20616280	81		XP_002956588.1|MDLRAQVRNYNMTLSNNKTPPPIKTEGKTENQHVKSLQSLSNGNEVPYDATLRTVIHEGSRTPKLPPRQTQKHPYLRLPIWPHQRQRQHQRQLGVPGRGREPEQIHVRQGPPSAPSSATSATSASPRWGSGNRGTSTTPPGGSLTEEVGGCDDGGDRRGGGSCGGGGGTVVSFDECIRKYGNVPSLRVLIMVAGTRGDVQPATALGVRLASHGHRVRLATHPPYRDLVYGAGLEFFPLAGDPRRMMELTVKHRAPRRPERVFRCGILP
27	ATG27	853261	Autophagy-related protein 27		ETF1	baker's yeast	NM_001181611.1	NP_012357.2	NC_001142.9	P46989	Cytoplasmic vesicle membrane.	NULL			Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9. {ECO:0000269|PubMed:12186856, ECO:0000269|PubMed:17135291, ECO:0000269|PubMed:17426440, ECO:0000269|PubMed:22826123}.		8641269,8849441,10688190,12186856,16107716,16269340,17135291,17297289,17426440,18467557,18829864,19840948,20093466,21196517,21232131,21987634,22282571,22447937,22615397,22940862,23904270,24586198,25385507,25557545	28	1->1,25->199,257->271	NP_012357.2|MVSKTWICGFISIITVVQALSCEKHDVLKKYQVGKFSSLTSTERDTPPSTTIEKWWINVCEEHNVEPPEECKKNDMLCGLTDVILPGKDAITTQIIDFDKNIGFNVEETESALTLTLKGATWGANSFDAKLEFQCNDNMKQDELTSHTWADKSIQLTLKGPSGCLKSKDDDKKNGDGDNGKDGDSEGKKPAKKAGGTSWFTWLFLYALLFTLIYLMVVSFLNTRGGSFQDFRAEFIQRSTQFLTSLPEFCKEVVSRILGRSTAQRGGYSAV
29	ATG29	855937	Autophagy-related protein 29			baker's yeast	NM_001183980.1	NP_015159.1	NC_001148.4	Q12092	Preautophagosomal structure.	NULL			Plays a role in autophagy. Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions. Plays also a role in mitophagy and regulation of filamentous growth. {ECO:0000269|PubMed:16289106, ECO:0000269|PubMed:17700056, ECO:0000269|PubMed:18287526, ECO:0000269|PubMed:19793921}.		8849441,9169875,11805837,14562095,16289106,16319894,16429126,16554755,18287526,18701704,19337029,19536198,19755117,19793921,19840948,20093466,20826334,21460040,21987634,22768199,22842922,22885598,23858448,23904270,23939028,24586198,25998554,26673895	28	1->54,87->213	NP_015159.1|MIMNSTNTVVYIKVKGRRPQGFLDPPKFEWNGTKERQLWTMVSNLNYSQDQIDWQNLSKIFETPEFFLKKRTYKLFAEHLELLQLQLEKKRDLEKYSNDQVNEGMSDLIHKYTPTLQNDNLLNVSASPLTTERQDSEEVETEVTNEALQHLQTSKILNIHKKTSDSENKPNDKLDKDGINKEMECGSSDDDLSSSLSVSKSALEEALMDRLQF
31	ATG31	851585	Autophagy-related protein 31		CIS1	baker's yeast	NM_001180330.1	NP_010305.1	NC_001136.10	Q12421	Cytoplasm, cytoskeleton. Preautophagosomal structure.	NULL			Plays a role in starvation-induced autophagy. Involved in mitophagy. Functions with ATG17 and ATG29 at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions. May be involved in microtubule function, such as chromosome segregation and karyogamy. {ECO:0000269|PubMed:17362880, ECO:0000269|PubMed:18287526, ECO:0000269|PubMed:19793921, ECO:0000269|PubMed:9348527}.		8849441,9169867,9348527,11283351,11805837,14562095,16319894,16554755,17237519,17362880,18087042,18287526,18497569,18701704,19337029,19755117,19793921,19840948,20093466,20489023,22768199,23858448,23904270,23939028,25773276,25998554,26673895	28		NP_010305.1|MNVTVTVYDKNVKYRLEENIKNNKGPSNDDQPAYNNESKSTDGSDYAMFPTNIKYIFEDNNDELVDSSDAALTAGIDKVGDELENVIIVQLDESGSLEDITLISDQYELLSHRTNSLSLEENQMRTLSSHGDDKSNDEEEELSVDSDRFRVDSDIELDVISQFCDLSPFLRDLSLNDLIKLYVTQNEQLQMLSNSV
32	ATG32	854660	Autophagy-related protein 32		ECM37	baker's yeast	NM_001179494.1	NP_012120.1	NC_001141.2	P40458	Mitochondrion outer membrane.	NULL			Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation. {ECO:0000269|PubMed:19619494, ECO:0000269|PubMed:19619495, ECO:0000269|PubMed:19770589, ECO:0000269|PubMed:19793921, ECO:0000269|PubMed:21576396, ECO:0000269|PubMed:22157017, ECO:0000269|PubMed:22308029, ECO:0000269|PubMed:22643220, ECO:0000269|PubMed:22914317}.		8849441,9169870,16554755,18087042,19619494,19619495,19736522,19770589,20093466,21757540,22140548,22282571,22308029,22384331,22940862,23209445,23810512,24025448,24586198,24838945,25287303,26079297,26438722	28		NP_012120.1|MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
33	MTOR	2475	Serine/threonine-protein kinase mTOR	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1|SKS	human	NM_004958.3,XM_005263438.1,XM_011541166.1,XR_244786.1	NP_004949.1,XP_005263495.1,XP_011539468.1	NC_000001.11,NC_018912.2,NG_033239.1,NT_032977.10,NW_004929289.1	P42345	Endoplasmic reticulum membrane.	NULL			Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1- mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1- pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser- 758', disrupting the interaction with AMPK and preventing activation of ULK1. Also prevents autophagy through phosphorylation of the autophagy inhibitor DAP. mTORC1 exerts a feedback control on upstream growth factor signaling that includes phosphorylation and activation of GRB10 a INSR-dependent signaling suppressor. Among other potential targets mTORC1 may phosphorylate CLIP1 and regulate microtubules. As part of the mTORC2 complex MTOR may regulate other cellular processes including survival and organization of the cytoskeleton. Plays a critical role in the phosphorylation at 'Ser-473' of AKT1, a pro-survival effector of phosphoinositide 3-kinase, facilitating its activation by PDK1. mTORC2 may regulate the actin cytoskeleton, through phosphorylation of PRKCA, PXN and activation of the Rho-type guanine nucleotide exchange factors RHOA and RAC1A or RAC1B. mTORC2 also regulates the phosphorylation of SGK1 at 'Ser-422'. Regulates osteoclastogensis by adjusting the expression of CEBPB isoforms (By similarity). {ECO:0000250|UniProtKB:Q9JLN9, ECO:0000269|PubMed:12087098, ECO:0000269|PubMed:12150925, ECO:0000269|PubMed:12150926, ECO:0000269|PubMed:12231510, ECO:0000269|PubMed:12718876, ECO:0000269|PubMed:14651849, ECO:0000269|PubMed:15268862, ECO:0000269|PubMed:15467718, ECO:0000269|PubMed:15545625, ECO:0000269|PubMed:15718470, ECO:0000269|PubMed:18497260, ECO:0000269|PubMed:18762023, ECO:0000269|PubMed:18925875, ECO:0000269|PubMed:20516213, ECO:0000269|PubMed:20537536, ECO:0000269|PubMed:21659604, ECO:0000269|PubMed:23429703, ECO:0000269|PubMed:23429704}.	Hs.338207	7539137,7809080,7822316,8008069,8083223,8660990,8662507,9092573,9099849,9405468,9434772,9465032,9653645,10089303,10200280,10325225,10364159,10567431,10660304,10664457,10698949,10702316,10753870,10779345,10910062,10942774,10971657,11114166,11279232,11287630,11426320,11438723,11602639,11691836,11691993,11729323,11733037,11777913,11853878,11884412,11914378,11930000,11967149,12000755,12030785,12080086,12105188,12145207,12150925,12150926,12172553,12231510,12242281,12271141,12370290,12408816,12477932,12558800,12604610,12665511,12718876,12719976,12747827,12796477,12807916,12813467,12820960,12912989,14578359,14668532,14679009,14729629,14743216,14970221,15001544,15004009,15028555,15056668,15066126,15150271,15161933,15218033,15268862,15284440,15292274,15317677,15342556,15388791,15452223,15459249,15467718,15489334,15489897,15496972,15522880,15539461,15576463,15580312,15584862,15604215,15605414,15623621,15624760,15632115,15632201,15657358,15659381,15702344,15708965,15718470,15723049,15755954,15760907,15767663,15772076,15796538,15802268,15809305,15843522,15854902,15878852,15896331,15899889,15905173,15953364,16006564,16027121,16049009,16098202,16098514,16099944,16109716,16141350,16183647,16221682,16242075,16282343,16286006,16341243,16354680,16354698,16407298,16427044,16452250,16467080,16541103,16543150,16603397,16631613,16652388,16710414,16786123,16798736,16818690,16824195,16837165,16847060,16849522,16870609,16874098,16884363,16912159,16912980,16914728,16915281,16916907,16919458,16922504,16927414,16929481,16954686,16959214,16962653,16963469,17016437,17018601,17028174,17043309,17052453,17075574,17102641,17110454,17114181,17148679,17215282,17253963,17277771,17289850,17318075,17329400,17329620,17351147,17360675,17363738,17372934,17386266,17409838,17461779,17463046,17470430,17482291,17483438,17488873,17545512,17553806,17562705,17562865,17565979,17595159,17604271,17616684,17616691,17631500,17640392,17656678,17683115,17693255,17698027,17721885,17724079,17726467,17889116,17897319,17911267,17914450,17928295,17935273,17942603,17990907,17991864,17993259,17996122,18006825,18030348,18048359,18056791,18160036,18215133,18235224,18247380,18250445,18276609,18292222,18337562,18337751,18339839,18339899,18348264,18351386,18372248,18395956,18413763,18423201,18426977,18434090,18483275,18490760,18494264,18497260,18505677,18511708,18519641,18548093,18550814,18563337,18566586,18566587,18570873,18596736,18612547,18622747,18650380,18652687,18658153,18660489,18678646,18697743,18702307,18704194,18715846,18722121,18725988,18757300,18762023,18769127,18769147,18776922,18787170,18794342,18807177,18813808,18824293,18826385,18831768,18842593,18848473,18924132,18925875,18926585,18929564,18945681,18948269,18953439,18955708,18980674,18990449,19018001,19019920,19020722,19020730,19054297,19074768,19078992,19090006,19098000,19107520,19107873,19108833,19114562,19121088,19145465,19147678,19147764,19147772,19147966,19155728,19164214,19176054,19176518,19176689,19201859,19203585,19203829,19211835,19222999,19223493,19223902,19225151,19225536,19234517,19240722,19244117,19258318,19285014,19293424,19299575,19301157,19321861,19331815,19341427,19357233,19371356,19373664,19402821,19414743,19416884,19446321,19454477,19487463,19489223,19505958,19509151,19535348,19539012,19553685,19553815,19553991,19561084,19564927,19587219,19608873,19615795,19619545,19624311,19648884,19654299,19657638,19679016,19680556,19690328,19698731,19724909,19725049,19726679,19739122,19757306,19771169,19788500,19789507,19789631,19794149,19797172,19815051,19838215,19864431,19875696,19875983,19881535,19889638,19897009,19914247,19935716,19935854,19936974,19946888,19949304,19954658,19955088,19956179,19956839,19956876,19956903,19966861,20005306,20009539,20019839,20022946,20030877,20038818,20048174,20053679,20061787,20070283,20080789,20081105,20093977,20133820,20137118,20145209,20150565,20153512,20157617,20160076,20166697,20166753,20169205,20176935,20182617,20190810,20196784,20204306,20207176,20226010,20227368,20232298,20232305,20233713,20236941,20299603,20308064,20335217,20338061,20338997,20339946,20354165,20354178,20360610,20368287,20372862,20375166,20375271,20379614,20381137,20386866,20388784,20395440,20410302,20412774,20424163,20424326,20427287,20427710,20438709,20439490,20447721,20453000,20457610,20459645,20459775,20460933,20479250,20480226,20488790,20491627,20517583,20537536,20542007,20542987,20543138,20562859,20606252,20607654,20622004,20628002,20630061,20656459,20668229,20673489,20679884,20717925,20727662,20727967,20801936,20805015,20805416,20809949,20810650,20811722,20811725,20817788,20823133,20828737,20837708,20855840,20857497,20861467,20864032,20874802,20884115,20929525,20960030,20978191,21033251,21035469,21035497,21040950,21045808,21046231,21048031,21062981,21062993,21071439,21071597,21092676,21095582,21113813,21123297,21145759,21159731,21170086,21177249,21177869,21199794,21203441,21212465,21223797,21228927,21239045,21242970,21246613,21258367,21264294,21266827,21276607,21277936,21283628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LEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW,XP_011539468.1|MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGIP
33	Mtor	56717	Serine/threonine-protein kinase mTOR	Mtor	2610315D21Rik|AI327068|FRAP|FRAP2|Frap1|RAFT1|RAPT1|flat	mouse	NM_020009.2,XM_006539077.1	NP_064393.2,XP_006539140.1	AC_000026.1,NC_000070.6,NT_166299.2,NT_187033.1,NW_001030773.1	Q9JLN9	Endoplasmic reticulum membrane.	NULL			Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1- mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1- pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser- 758', disrupting the interaction with AMPK and preventing activation of ULK1. Also prevents autophagy through phosphorylation of the autophagy inhibitor DAP. mTORC1 exerts a feedback control on upstream growth factor signaling that includes phosphorylation and activation of GRB10 a INSR-dependent signaling suppressor. Among other potential targets mTORC1 may phosphorylate CLIP1 and regulate microtubules. As part of the mTORC2 complex MTOR may regulate other cellular processes including survival and organization of the cytoskeleton. Plays a critical role in the phosphorylation at 'Ser-473' of AKT1, a pro-survival effector of phosphoinositide 3-kinase, facilitating its activation by PDK1. mTORC2 may regulate the actin cytoskeleton, through phosphorylation of PRKCA, PXN and activation of the Rho-type guanine nucleotide exchange factors RHOA and RAC1A or RAC1B. mTORC2 also regulates the phosphorylation of SGK1 at 'Ser-422'. Regulates osteoclastogensis by adjusting the expression of CEBPB isoforms (PubMed:19440205). {ECO:0000269|PubMed:11792863, ECO:0000269|PubMed:15467718, ECO:0000269|PubMed:15545625, ECO:0000269|PubMed:16221682, ECO:0000269|PubMed:16915281, ECO:0000269|PubMed:16962653, ECO:0000269|PubMed:18046414, ECO:0000269|PubMed:19440205, ECO:0000269|PubMed:21258367, ECO:0000269|PubMed:21659604}.	Mm.21158	7809080,8530339,8889548,9334222,10079223,10349636,10922068,11042159,11076861,11217851,11687517,11707573,11875068,12134068,12140361,12150926,12393646,12466851,12477932,12801981,12957289,14534328,14561707,14579029,14610273,14612424,14634209,14684988,14691534,15156201,15185396,15254091,15254238,15358118,15467718,15485918,15489334,15545625,15550386,15576463,15632201,15672593,15723049,15772076,15788477,15895362,15928081,15963500,15967113,16027121,16099428,16141072,16141073,16183639,16221682,16282343,16286931,16341243,16364254,16537399,16541103,16602821,16677760,16714284,16772532,16906226,16912167,16915281,16962829,16963469,16996801,17005556,17006666,17043309,17052453,17141160,17178807,17229738,17245434,17273797,17284572,17290308,17301289,17322895,17329361,17369192,17386266,17405917,17516572,17562867,17588951,17596519,17616684,17616691,17635924,17641780,17664276,17670836,17689501,17698586,17724683,17825298,17941081,17942753,17962806,17971449,18006825,18039669,18046414,18057094,18070882,18079193,18094233,18160036,18162531,18198186,18199538,18207367,18215134,18235224,18270303,18283119,18316213,18326485,18339627,18342602,18347059,18372248,18381428,18453534,18468454,18474609,18479958,18483275,18492954,18566586,18568033,18614546,18616983,18650380,18664580,18703865,18725988,18767117,18768473,18768809,18773906,18787170,18809716,18824293,18842593,18848473,18851840,18924132,18929564,18949383,18974106,18980674,18988856,18990450,19013287,19020099,19047368,19060896,19097998,19138937,19139015,19147764,19151711,19165175,19185849,19190264,19228596,19237506,19255143,19258318,19266163,19293429,19356717,19389373,19393224,19406939,19414743,19422788,19440205,19447494,19474313,19481146,19483717,19487463,19497867,19535330,19538929,19539012,19541609,19543266,19552768,19556857,19561084,19567830,19586661,19593385,19620286,19622833,19628573,19634141,19642171,19644667,19648913,19690069,19692352,19698731,19703998,19704009,19710174,19729590,19733540,19829382,19850877,19864431,19877273,19886750,19917692,19934303,19934433,20004186,20008564,20022946,20038583,20041152,20042677,20045038,20053679,20058701,20060329,20060330,20061787,20068142,20104019,20126553,20145209,20151325,20166753,20167228,20169165,20178983,20196784,20197621,20203102,20231314,20335217,20347422,20347762,20352108,20354178,20388784,20388826,20396791,20412774,20424163,20424326,20429048,20444807,20445056,20466002,20498714,20530239,20542987,20554235,20566686,20574055,20606252,20615870,20615969,20644257,20668162,20717955,20727922,20801936,20802152,20823133,20837708,20847160,20847591,20852388,20852647,20858757,20862226,20864032,20933441,20935455,20935515,20972332,20972424,21040901,21041654,21045808,21062985,21078910,21079150,21095582,21106878,21113129,21135502,21179166,21189286,21199794,21200439,21212100,21228155,21233250,21238928,21258367,21266573,21267068,21268018,21283818,21300751,21307309,21310925,21320501,21325052,21336308,21339483,21343542,21349854,21358638,21360636,21382453,21387562,21393858,21413931,21439266,21444676,21454706,21462085,21463685,21464307,21470048,21471201,21501832,21511183,21512002,21532529,21559457,21606591,21607286,21607293,21613414,21641396,21673516,21674478,21677750,21678406,21695255,21718677,21723501,21725971,21738705,21748792,21750711,21785161,21795849,21799304,21808151,21838918,21841000,21876130,21886784,21896734,21896779,21911744,21946849,21963787,21981924,21983129,21993994,22001647,22007913,22010857,22015718,22025690,22053105,22055460,22056141,22056783,22058153,22075384,22081627,22133684,22143799,22145042,22158946,22179044,22179112,22193387,22207131,22227194,22253885,22273489,22275355,22287635,22302821,22306200,22307088,22351927,22367541,22383528,22399302,22403008,22407942,22408252,22426621,22442136,22446027,22446186,22456226,22461615,22471963,22484424,22492229,22508056,22529334,22544753,22561297,22653655,22700793,22711601,22711699,22722868,22729283,22738676,22745686,22750207,22761730,22791749,22826320,22846606,22884327,22907434,22984623,23027611,23027865,23061908,23063798,23064282,23070543,23077579,23081858,23100423,23102618,23103253,23115080,23129577,23142783,23155049,23160380,23183047,23184952,23185335,23197407,23212520,23223576,23226562,23242809,23250913,23263183,23269193,23274896,23315073,23329839,23341605,23342106,23392671,23394946,23395832,23410496,23425014,23426372,23429704,23434734,23440206,23440873,23443503,23444404,23454121,23454868,23456828,23508953,23538752,23562079,23589074,23604129,23607966,23624629,23637172,23665330,23686362,23695213,23699409,23716557,23722550,23744272,23774212,23786956,23803853,23806777,23811944,23818585,23828865,23836929,23858034,23858058,23872956,23884148,23896646,23911927,23915343,23972597,23972959,23994476,24002653,24036451,24047696,24049142,24068000,24068326,24088573,24092877,24094105,24101522,24121838,24129405,24141387,24184801,24203997,24209762,24218567,24227713,24243565,24253377,24273170,24275666,24280772,24302719,24316214,24333417,24336796,24338587,24349533,24371138,24411482,24445950,24462113,24462873,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LGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAASAAAATSTEGSNSESEAESNENSPTPSPLQKKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKAGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW
33	TOR1	853529	Serine/threonine-protein kinase TOR1		DRR1	baker's yeast	NM_001181724.1	NP_012600.1	NC_001142.9	P35169	Cell membrane.	NULL			Phosphatidylinositol 3-kinase homolog, component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA gene expression, and rRNA processing. TORC1 positively controls protein biosynthesis by regulation of mRNA stability, translation initiation factor activity, and high-affinity amino acid permeases that serve to provide amino acids for use by the translation machinery. TORC1 also promotes growth by sequestering a number of nutrient and general stress-responsive transcription factors in the cytoplasm. TORC1 negatively controls macroautophagy, a process to recycle surplus cytoplasmic mass under nutrient starvation conditions. TORC1 controls many of these processes via TIP41-TAP42-mediated inhibition of the type 2A-related phosphatases PP2A and SIT4 (PubMed:10198052, PubMed:10329624, PubMed:10604478, PubMed:10995454, PubMed:11741537, PubMed:15620355, PubMed:7606777, PubMed:8741837, PubMed:9539725, PubMed:9843498). In nutrient rich conditions, responsible for the phosphorylation of AGC S6 kinase (S6K) YPK3, activating YPK3 kinase activity and promoting phosphorylation of ribosomal protein S6 (PubMed:25767889). Phosphorylates kinase SCH9 at 6 amino acids in the C-terminus, activating SCH9 kinase activity to properly regulate ribosome biogenesis, translation initiation, and entry into stationary phase (PubMed:17560372). {ECO:0000269|PubMed:10198052, ECO:0000269|PubMed:10329624, ECO:0000269|PubMed:10604478, ECO:0000269|PubMed:10995454, ECO:0000269|PubMed:11741537, ECO:0000269|PubMed:15620355, ECO:0000269|PubMed:17560372, ECO:0000269|PubMed:25767889, ECO:0000269|PubMed:7606777, ECO:0000269|PubMed:8741837, ECO:0000269|PubMed:9539725, ECO:0000269|PubMed:9843498}.		8186460,8641269,8741837,8849441,9096347,9207794,9398673,9461583,10198052,10329624,10436010,10899009,10940301,10973982,11078525,11997479,12171921,12408816,12624103,12631735,12719473,14736892,15326168,15539461,15598536,15620355,15643061,15772072,15989961,16269340,16308562,16397762,16554755,16874307,16900101,16923813,16980405,17403371,17507646,17560372,17565946,17603109,17679098,17698581,17846631,17875934,17923092,17989363,18087042,18225956,18245087,18408719,18423200,18435413,18493323,18513215,18552287,18616809,18689878,18690010,18723607,18753406,18805955,18812505,18949037,19061648,19073887,19106085,19160490,19269370,19328065,19424415,19521502,19557187,19574957,19748353,19805182,19805410,19805817,19835169,19901341,19995911,20042596,20065090,20093466,20157544,20157595,20388713,20457600,20457806,20489023,20526336,20617129,20697716,20702584,21035341,21107429,21118957,21127252,21324902,21331237,21343333,21368139,21490424,21552543,21623372,21641548,21655263,21757539,21840851,21902802,21987634,22043304,22068328,22199229,22227188,22282571,22307609,22445487,22451491,22547071,22622083,22646158,22727621,22960125,23097491,23222640,23223232,23363605,23481038,23660670,23697803,23704987,23716719,23747251,23832372,24035500,24116217,24239358,24465216,24500206,24514902,24586198,24649827,24664350,24704685,24725177,24834721,25046117,25061043,25063813,25238629,25446900,25512609,25767889,25822194,25855033,25901273,26079297,26322385,26456335,26510498,26582391,26659116,26700129	28	1->73,105->111,215->228,395->406,437->449,519->587,1160->1236,1356->1382,1413->1426,1542->1641,1766->1801,1856->1951,2355->2414	NP_012600.1|MEPHEEQIWKSKLLKAANNDMDMDRNVPLAPNLNVNMNMKMNASRNGDEFGLTSSRFDGVVIGSNGDVNFKPILEKIFRELTSDYKEERKLASISLFDLLVSLEHELSIEEFQAVSNDINNKILELVHTKKTSTRVGAVLSIDTLISFYAYTERLPNETSRLAGYLRGLIPSNDVEVMRLAAKTLGKLAVPGGTYTSDFVEFEIKSCLEWLTASTEKNSFSSSKPDHAKHAALLIITALAENCPYLLYQYLNSILDNIWRALRDPHLVIRIDASITLAKCLSTLRNRDPQLTSQWVQRLATSCEYGFQVNTLECIHASLLVYKEILFLKDPFLNQVFDQMCLNCIAYENHKAKMIREKIYQIVPLLASFNPQLFAGKYLHQIMDNYLEILTNAPANKIPHLKDDKPQILISIGDIAYEVGPDIAPYVKQILDYIEHDLQTKFKFRKKFENEIFYCIGRLAVPLGPVLGKLLNRNILDLMFKCPLSDYMQETFQILTERIPSLGPKINDELLNLVCSTLSGTPFIQPGSPMEIPSFSRERAREWRNKNILQKTGESNDDNNDIKIIIQAFRMLKNIKSRFSLVEFVRIVALSYIEHTDPRVRKLAALTSCEIYVKDNICKQTSLHSLNTVSEVLSKLLAITIADPLQDIRLEVLKNLNPCFDPQLAQPDNLRLLFTALHDESFNIQSVAMELVGRLSSVNPAYVIPSIRKILLELLTKLKFSTSSREKEETASLLCTLIRSSKDVAKPYIEPLLNVLLPKFQDTSSTVASTALRTIGELSVVGGEDMKIYLKDLFPLIIKTFQDQSNSFKREAALKALGQLAASSGYVIDPLLDYPELLGILVNILKTENSQNIRRQTVTLIGILGAIDPYRQKEREVTSTTDISTEQNAPPIDIALLMQGMSPSNDEYYTTVVIHCLLKILKDPSLSSYHTAVIQAIMHIFQTLGLKCVSFLDQIIPTILDVMRTCSQSLLEFYFQQLCSLIIIVRQHIRPHVDSIFQAIKDFSSVAKLQITLVSVIEAISKALEGEFKRLVPLTLTLFLVILENDKSSDKVLSRRVLRLLESFGPNLEGYSHLITPKIVQMAEFTSGNLQRSAIITIGKLAKDVDLFEMSSRIVHSLLRVLSSTTSDELSKVIMNTLSLLLIQMGTSFAIFIPVINEVLMKKHIQHTIYDDLTNRILNNDVLPTKILEANTTDYKPAEQMEAADAGVAKLPINQSVLKSAWNSSQQRTKEDWQEWSKRLSIQLLKESPSHALRACSNLASMYYPLAKELFNTAFACVWTELYSQYQEDLIGSLCIALSSPLNPPEIHQTLLNLVEFMEHDDKALPIPTQSLGEYAERCHAYAKALHYKEIKFIKEPENSTIESLISINNQLNQTDAAIGILKHAQQHHSLQLKETWFEKLERWEDALHAYNEREKAGDTSVSVTLGKMRSLHALGEWEQLSQLAARKWKVSKLQTKKLIAPLAAGAAWGLGEWDMLEQYISVMKPKSPDKEFFDAILYLHKNDYDNASKHILNARDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKYKQLPPNSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQDLQIWIKFANLCRKSGRMRLANKALNMLLEGGNDPSLPNTFKAPPPVVYAQLKYIWATGAYKEALNHLIGFTSRLAHDLGLDPNNMIAQSVKLSSASTAPYVEEYTKLLARCFLKQGEWRIATQPNWRNTNPDAILGSYLLATHFDKNWYKAWHNWALANFEVISMVQEETKLNGGKNDDDDDTAVNNDNVRIDGSILGSGSLTINGNRYPLELIQRHVVPAIKGFFHSISLLETSCLQDTLRLLTLLFNFGGIKEVSQAMYEGFNLMKIENWLEVLPQLISRIHQPDPTVSNSLLSLLSDLGKAHPQALVYPLTVAIKSESVSRQKAALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELWYEGLEDASRQFFVEHNIEKMFSTLEPLHKHLGNEPQTLSEVSFQKSFGRDLNDAYEWLNNYKKSKDINNLNQAWDIYYNVFRKITRQIPQLQTLDLQHVSPQLLATHDLELAVPGTYFPGKPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAKKIPLNIEHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQTGIPLPLINPSELLRKGAITVEEAANMEAEQQNETKNARAMLVLRRITDKLTGNDIKRFNELDVPEQVDKLIQQATSIERLCQHYIGWCPFW
34	TOR2	853632	Serine/threonine-protein kinase TOR2		DRR2	baker's yeast	NM_001179768.1	NP_012719.2	NC_001143.9	P32600	Cell membrane.	NULL			Phosphatidylinositol 3-kinase homolog, component of both TORC1 and TORC2. TORC1 regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA gene expression, and rRNA processing. TORC1 positively controls protein biosynthesis by regulation of mRNA stability, translation initiation factor activity, and high-affinity amino acid permeases that serve to provide amino acids for use by the translation machinery. TORC1 also promotes growth by sequestering a number of nutrient and general stress-responsive transcription factors in the cytoplasm. TORC1 negatively controls macroautophagy, a process to recycle surplus cytoplasmic mass under nutrient starvation conditions. TORC1 controls many of these processes via TIP41-TAP42-mediated inhibition of the type 2A-related phosphatases PP2A and SIT4 (PubMed:10198052, PubMed:10329624, PubMed:10604478, PubMed:11741537, PubMed:15620355, PubMed:7606777, PubMed:8741837, PubMed:9539725, PubMed:9843498). In nutrient rich conditions, responsible for the phosphorylation of AGC S6 kinase (S6K) YPK3, activating YPK3 kinase activity and promoting phosphorylation of ribosomal protein S6 (PubMed:25767889). Phosphorylates kinase SCH9 at 6 amino acids in the C-terminus, activating SCH9 kinase activity to properly regulate ribosome biogenesis, translation initiation, and entry into stationary phase (PubMed:17560372). TORC2 regulates cell cycle-dependent polarization of the actin- cytoskeleton, cell wall integrity, and receptor endocytosis. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway by activating the RHO1 guanine nucleotide exchange factor ROM2. TORC2 phosphorylates the AGC kinase YPK2, an upstream effector of the cell integrity pathway. TORC2 negatively regulates calcineurin-dependent stress signaling via phosphorylation of its effector SLM1-SLM2 (PubMed:14593073, PubMed:15372071, PubMed:16055732, PubMed:16959779, PubMed:8846782, PubMed:8943012). {ECO:0000269|PubMed:10198052, ECO:0000269|PubMed:10329624, ECO:0000269|PubMed:10604478, ECO:0000269|PubMed:11741537, ECO:0000269|PubMed:14593073, ECO:0000269|PubMed:15372071, ECO:0000269|PubMed:15620355, ECO:0000269|PubMed:16055732, ECO:0000269|PubMed:16959779, ECO:0000269|PubMed:17560372, ECO:0000269|PubMed:25767889, ECO:0000269|PubMed:7606777, ECO:0000269|PubMed:8741837, ECO:0000269|PubMed:8846782, ECO:0000269|PubMed:8943012, ECO:0000269|PubMed:9539725, ECO:0000269|PubMed:9843498}.		7499212,8186460,8196765,8754819,8846782,8849441,8943012,9038344,9398673,9461583,9475724,9545237,9804843,9811607,9826521,9843498,10198052,10329624,10940301,10973982,11057898,11839800,12207708,12408816,12631735,12719473,14576278,14593073,14736892,15265867,15689497,15704212,16002396,16055732,16118191,16155567,16554755,16823961,16874307,16959779,17507646,17846631,17923092,18245087,18249174,18408719,18552287,18723607,18805955,18812505,19269370,19805182,19805410,20093466,20489023,20526336,20617129,21035341,21118957,21232131,21324902,21552543,21623372,22207764,22282571,22296835,22298706,22307609,22445487,22496512,22940862,23222640,23390603,23625923,23660670,24035500,24465216,24629393,24834721,25026036,25253719,25624345,26028537,26700129	28	1->83,123->142,1150->1274,1317->1325,1392->1440,1550->1596,1635->1648,1688->1707,1773->1841,1885->1954,2359->2418	NP_012719.2|MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMSTTSNTDSNHNGPNDSGRVITGSAGHIGKISFVDSELDTTFSTLNLIFDKLKSDVPQERASGANELSTTLTSLAREVSAEQFQRFSNSLNNKIFELIHGFTSSEKIGGILAVDTLISFYLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAANTLGRLTVPGGTLTSDFVEFEVRTCIDWLTLTADNNSSSSKLEYRRHAALLIIKALADNSPYLLYPYVNSILDNIWVPLRDAKLIIRLDAAVALGKCLTIIQDRDPALGKQWFQRLFQGCTHGLSLNTNDSVHATLLVFRELLSLKAPYLRDKYDDIYKSTMKYKEYKFDVIRREVYAILPLLAAFDPAIFTKKYLDRIMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISPYMTLILDNIREGLRTKFKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKIPSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQSFMKKTGESNDDITDAQILIQCFKMLQLIHHQYSLTEFVRLITISYIEHEDSSVRKLAALTSCDLFIKDDICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLLFMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESATLLCTLINSSDEVAKPYIDPILDVILPKCQDASSAVASTALKVLGELSVVGGKEMTRYLKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKTENNPHIRRGTVRLIGILGALDPYKHREIEVTSNSKSSVEQNAPSIDIALLMQGVSPSNDEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVMRSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIKLQITIISVIESISKALEGEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIVVRMTEYSAGSLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGDRELTKATMNTLSLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENEVPERKNYEDEMQVTKLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRSCSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLNLVEFMEHDDKPLPIPIHTLGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQLHQTDSAIGILKHAQQHNELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKLRSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQSPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQVRIKFANLCRKSGRMALAKKVLNTLLEETDDPDHPNTAKASPPVVYAQLKYLWATGLQDEALKQLINFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWRVCLQPKWRLSNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISMLTSVSKKKQEGSDASSVTDINEFDNGMIGVNTFDAKEVHYSSNLIHRHVIPAIKGFFHSISLSESSSLQDALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSLLSDLGKAHPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGRDLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENEHKNAIRNARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW
38	VPS34	850941	Phosphatidylinositol 3-kinase VPS34		END12|PEP15|STT8|VPL7|VPS7|VPT29	baker's yeast	NM_001182127.1	NP_013341.1	NC_001144.5	P22543	NULL	NULL			Phosphatidylinositol 3-kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy- specific VPS34 PI3-kinase complex I. This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure. Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3- kinase complex II. This second complex is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes (probably through the synthesis of a specific pool of phosphatidylinositol 3-phosphate recruiting the retromer to the endosomes). Its activation by VPS15 may lead to the phosphorylation of phosphatidylinositol in the sorting compartment membrane. Finally, it might also be involved in ethanol tolerance and cell wall integrity. {ECO:0000269|PubMed:11157979, ECO:0000269|PubMed:11523784, ECO:0000269|PubMed:12244127, ECO:0000269|PubMed:2247081, ECO:0000269|PubMed:2555343, ECO:0000269|PubMed:3062374, ECO:0000269|PubMed:7929582, ECO:0000269|PubMed:7989323, ECO:0000269|PubMed:8385367, ECO:0000269|PubMed:8387919}.		7929582,7989323,8385367,8387919,8849441,9169871,10359603,10637310,11157979,11689570,11847108,14731957,15634212,16421251,16429126,16487579,16554755,16729061,16839886,17565946,18533003,18612650,18676811,19001347,20489023,20729555,21121900,22833678,23332755,23335340,23904270,24165940,26086550	28	1->61,149->303,852->875	NP_013341.1|MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQIPFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT
38	VOLCADRAFT_40672	9617169				volvox	XM_002953955.1	XP_002954001.1	NW_003307582.1	D8U5M8	NULL	NULL					20616280	81		XP_002954001.1|GSGGGGGGGGIIRLLDPEVGRDNPAELKAQKLARGLQRGVLDRDLKPNSEERKKLQAILKLPPNKPLHAEERALLWRFRASLTADTRALTKFLQCVDWSDAAEAKQAAELMRQWAPISAADALELLSPDFRAEVVREHAVKALQVEVEVEERRQYLLQLVQALRYEAADGSRLASFLVARAAEDPALAIQLHWYLFCELDDPGFGQRARALHSSLLDALERRAGPVGLAVKNTIRKQVDLVKQLKAVIRELKSAKIKAARATERLREMISESGPCGELTALRVPLPLDPNIVLAGIVPKECAVFKSAMMPLKLSFRIEAAPFNWRAPPTPPAAEGGVGGPGLARGTAASPHPHHHQQQHHHILLPWQHHHSPVGGAAGGSSHHSAGAGSSSSGHHRHQHGPTADPLSLLPTRTGIVQAPAGAGGGSGSAAAAAVTSASSHHGQHPAAVAAALPPPPYGAPGPILDGYRCWLIYKKGDDLRQDHFILQMISLMDRMLKRENLDLRLTPYKVLPTSCDDGLLEFVPSVPLSAVLAEHRTIHRFLALTQADPTGPFGLRGEVVETFVRSCAGYCVMTYILGVGDRHLDNLMLTNDGRLFHIDFGYILGNDPKPFPPPMKLCKEMIEAMGGQGSEYYKQFRMFACEAYNILRKRADLILSLFHLMAGASIEAIRADPEKAILKLQDKFRLDFDDEAAVEWMQGLINESATALLPQLVETTHRWAQYWR
39	MAPK1	5594	Mitogen-activated protein kinase 1	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	human	NM_002745.4,NM_138957.3	NP_002736.3,NP_620407.1	NC_000022.11,NC_018933.2,NG_023054.2,NT_011520.13,NW_004929430.1	P28482,Q1HBJ4,Q499G7	NULL	NULL			Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.	Hs.431850	1319925,1330687,1347949,1378617,1540184,1648701,1712480,2032290,7535768,7566346,7569900,7737129,7768935,7777512,7816602,7876160,7957875,8083223,8157000,8208531,8221888,8248197,8290275,8381049,8384717,8386592,8388392,8389479,8407983,8506364,8552640,8586671,8607977,8618896,8626452,8626561,8626571,8631994,8639570,8794306,8806671,8816480,8846788,8900182,8939914,8941362,8960373,8994038,9013873,9029147,9030579,9045910,9069267,9092573,9130707,9155017,9199329,9199504,9204908,9207092,9211903,9223324,9325171,9335504,9343414,9388255,9403476,9405468,9430688,9440696,9453574,9528769,9535905,9535909,9535927,9558095,9564043,9565682,9592082,9604935,9621077,9628874,9632734,9649500,9658081,9687510,9725910,9744883,9771888,9788880,9792705,9832145,9857190,9858547,9872331,9915826,9973222,10027715,10051431,10066798,10074203,10187842,10194762,10197981,10206983,10207078,10224087,10230405,10318905,10330152,10347142,10371216,10388555,10405182,10409742,10415025,10419510,10446219,10490027,10509564,10512765,10521505,10567572,10581001,10601328,10617468,10627507,10635328,10644696,10660621,10692442,10702794,10706702,10706854,10712923,10733581,10737616,10747973,10748182,10757792,10762698,10779345,10780709,10799874,10801826,10866661,10878576,10910078,10915800,10942774,10958679,10958680,10958792,10969079,10982368,10988299,10993892,10996427,11013076,11035004,11044099,11114188,11134045,11153078,11157753,11181841,11205744,11226163,11226259,11258664,11260070,11266467,11278335,11278395,11278799,11279118,11279232,11279280,11313464,11350735,11350938,11352917,11358671,11403955,11408587,11409852,11409876,11409918,11416124,11431474,11481231,11489891,11493009,11500490,11504923,11520933,11532249,11549292,11570821,11579140,11581251,11583024,11585926,11606045,11702783,11726657,11741541,11741894,11744690,11748628,11756441,11773377,11776327,11781324,11786537,11788583,11805108,11805112,11823456,11840291,11840343,11857080,11861509,11865055,11866440,11866540,11867630,11876253,11878930,11883936,11884401,11891214,11896055,11904305,11914583,11923300,11930938,11937531,11943771,11952164,11958689,11960991,11961297,11971971,11983899,11988087,11994045,12006497,12016217,12030372,12032872,12038794,12039864,12048211,12050114,12054624,12058028,12058067,12076252,12077112,12079429,12081892,12081893,12082090,12082091,12082107,12089333,12091386,12093745,12095140,12095152,12105188,12121974,12140374,12149268,12149431,12149432,12151316,12151396,12161424,12167619,12175859,12177807,12183542,12200131,12206715,12218048,12220502,12220533,12226093,12239168,12239215,12351702,12354773,12356731,12356755,12362243,12379481,12387894,12388423,12391149,12393542,12408764,12419216,12435397,12438317,12441075,12444202,12446729,12450322,12456688,12460991,12464620,12473660,12477932,12478298,12482669,12491158,12505790,12508271,12529294,12531514,12536241,12538349,12538595,12540369,12540563,12551925,12555071,12556484,12556561,12562867,12576315,12576423,12588875,12592337,12592382,12594221,12603851,12606501,12611773,12618428,12618431,12624094,12637339,12637502,12637525,12643788,12663671,12665511,12665513,12665801,12676937,12682854,12690112,12690113,12697810,12714584,12727980,12734410,12754301,12759139,12760422,12763138,12774925,12775419,12788955,12792650,12794004,12794087,12794156,12801888,12810719,12821662,12826588,12832284,12832467,12837293,12840032,12871860,12883725,12894225,12897141,12917419,12937136,12937895,12943720,12947314,12947325,12957654,12960100,12963735,12972603,12972619,12975377,14500714,14500727,14511403,14530346,14532121,14551204,14551213,14570886,14575703,14581471,14587029,14592976,14602725,14620918,14622970,14634064,14636584,14636891,14654779,14655753,14671106,14672918,14676207,14676217,14676843,14691575,14694183,14701866,14702039,14711824,14714552,14715628,14729955,14742298,14744867,14762791,14764702,14766231,14960303,14968112,14970210,14970219,14985328,14988395,14993287,14997206,15016620,15021912,15030407,15031289,15033443,15033452,15037631,15040022,15041276,15059773,15064239,15068691,15069082,15078890,15081531,15087455,15094067,15116093,15118098,15128760,15128788,15133037,15143154,15155723,15173068,15173174,15184391,15187168,15210690,15210734,15225643,15241487,15243131,15247230,15247297,15249224,15253667,15276183,15292226,15292252,15300592,15322023,15342917,15343382,15347670,15355986,15356145,15358166,15358203,15371627,15379552,15380617,15383283,15459189,15485655,15489334,15489336,15529758,15542607,15542825,15544353,15545519,15557324,15563472,15588985,15592455,15595556,15603708,15610077,15616014,15616583,15632082,15632084,15653554,15654082,15655247,15655348,15664191,15671028,15689238,15699045,15713638,15719130,15721302,15721486,15728253,15728359,15735702,15739119,15746430,15757891,15777705,15778365,15778391,15782123,15809051,15814736,15850461,15851026,15851480,15857981,15861134,15880942,15882975,15890751,15897893,15923189,15928037,15928662,15951569,15952796,15967790,15967991,15979846,15985432,16027724,16039586,16045329,16047735,16051177,16081426,16093354,16094384,16131083,16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66182,25874498,25884419,25889655,25896662,25913664,25921289,25937083,25943894,25948734,25953087,25962735,25963833,25976462,26004135,26041108,26041847,26044620,26046540,26047699,26051103,26054744,26062551,26080397,26095851,26096876,26117268,26163656,26176534,26182292,26186194,26247533,26253279,26267534,26267535,26269597,26324936,26344197,26391660,26408092,26475492,26514924,26549023,26574555,26612919,26752685	15		NP_002736.3|MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS,NP_620407.1|MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
39	MAPK3	5595		MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	human	NM_001040056.2,NM_001109891.1,NM_002746.2,XR_243293.1	NP_001035145.1,NP_001103361.1,NP_002737.2	NC_000016.10,NC_018927.2,NG_029936.1,NT_187260.1,NW_004929400.1	L7RXH5,P27361,Q9BWJ1	NULL	NULL				Hs.861	862676,1319925,1322499,1347949,1463607,1540184,1922387,7535768,7687743,7739560,7836374,8112321,8152805,8197172,8208531,8226933,8290275,8325880,8376365,8388392,8407983,8423803,8506364,8552640,8618896,8626571,8626767,8631994,8632909,8639570,8794306,8806671,8939914,8940068,9006895,9020136,9054461,9069267,9126608,9130707,9155018,9211903,9218456,9223324,9235954,9325171,9343414,9388255,9403476,9446616,9525956,9535905,9535909,9535927,9558095,9564043,9621077,9628824,9658081,9687510,9733512,9792677,9792705,9857190,9872331,9915826,10027715,10066421,10074203,10187842,10194762,10206983,10224087,10339476,10347142,10383391,10402467,10415025,10419510,10431817,10446219,10509564,10521505,10551817,10559944,10570282,10574913,10581001,10597297,10617468,10627507,10635328,10648599,10677502,10702794,10712923,10725920,10727525,10748187,10780709,10799874,10869359,10912793,10915800,10958792,10982368,11027280,11044099,11114188,11131153,11134045,11135364,11205744,11226163,11238443,11260070,11278799,11279232,11287604,11342557,11350938,11387337,11403955,11409852,11409918,11466319,11504923,11520933,11532249,11551945,11570821,11579140,11581251,11583024,11585926,11682603,11702783,11741541,11741977,11773377,11776327,11781324,11784715,11788583,11792123,11866440,11866540,11884401,11891214,11904305,11923300,11930938,11937531,11948414,11952164,11960991,11961297,11986622,11988087,12030372,12032872,12048211,12049732,12063245,12081892,12082090,12082091,12089333,12095152,12118371,12121974,12167619,12183542,12193595,12200131,12218048,12226077,12239168,12356731,12362243,12388423,12408764,12441075,12446729,12456688,12473660,12477932,12482669,12491158,12529294,12531514,12538349,12538595,12540563,12555071,12562867,12576423,12594221,12603851,12606501,12624094,12624098,12637339,12637502,12637525,12643788,12663671,12676937,12682854,12689928,12690112,12697810,12727216,12754301,12759139,12763138,12775419,12792650,12794156,12810719,12821662,12832284,12832467,12840032,12937136,12943720,12947325,12960100,12975377,14499342,14515181,14530346,14532121,14551213,14559906,14575703,14587029,14592976,14602725,14622970,14634064,14651992,14671106,14676207,14676217,14701866,14702039,14711824,14712216,14714552,14744867,14960303,14985328,14988395,15016620,15030407,15040022,15059773,15064239,15068691,15069082,15078890,15081531,15113754,15118098,15128760,15133517,15143154,15144186,15173068,15184391,15210690,15210734,15243131,15247230,15247297,15249224,15256218,15276183,15292176,15302935,15321994,15322023,15336571,15342917,15347670,15355986,15356145,15364926,15371627,15379552,15469820,15471881,15489334,15509801,15542825,15544353,15545519,15563472,15588985,15603708,15616583,15642734,15653554,15655247,15655348,15671028,15689238,15721302,15721486,15728253,15735702,15739119,15746430,15757891,15778365,15782123,15784503,15809051,15814736,15861134,15878863,15879168,15880942,15890751,15919053,15923189,15950189,15951569,15967790,15967991,15985432,16047735,16050810,16081426,16149052,16153436,16156742,16209712,16239230,16242072,16253958,16273281,16278291,16278684,16280323,16287813,16291755,16317051,16321971,16332685,16344560,16368546,16373414,16395283,16406609,16414009,16428339,16436505,16456541,16461926,16492667,16515552,16533948,16538383,16539678,16556602,16569214,16574793,16580177,16581800,16582626,16617096,16621960,16624816,16626623,16644735,16670094,16687572,16699726,16705745,16735500,16741963,16794828,16796978,16810323,16813525,16814421,16820412,16820791,16844778,16849642,16920714,16926156,16941494,16954218,16990258,16995340,16998804,17016429,17035635,17068339,17068343,17081983,17131384,17142261,17149612,17182689,17192257,17209045,17212589,17215072,17237147,17237423,17255949,17267664,17273789,17274723,17290218,17294242,17297454,17303382,17303384,17311928,17317670,17322878,17341442,17351113,17382881,17388789,17406055,17410437,17411366,17427197,17443665,17453826,17458890,17464174,17478078,17496918,17504381,17510316,17513610,17519976,17522999,17525735,17526808,17543571,17560175,17565009,17575262,17581212,17582224,17583675,17615382,17620336,17622743,17627030,17634019,17644078,17652082,17662006,17686614,17695723,17728396,17825787,17850776,17868650,17879163,17881458,17884340,17889508,17889855,17897354,17906618,17921324,17932312,17936667,17938255,17942397,17942603,17967787,17983270,17991320,17991743,18006496,18022816,18029348,18034864,18036343,18055485,18063683,18065201,18070930,18079194,18079197,18086557,18086662,18087676,18092356,18095097,18160848,18164958,18165705,18166657,18174382,18187448,18189318,18210145,18212269,18224451,18245089,18245228,18263590,18266953,18270969,18271757,18276593,18280112,18280482,18280748,18284542,18288130,18292183,18296648,18327407,18328346,18332145,18358530,18365874,18372245,18378312,18387958,18398416,18405916,18410277,18414015,18423386,18424438,18424783,18426801,18426913,18433299,18434089,18434324,18443043,18448488,18463290,18477477,18487214,18508903,18516291,18535203,18538010,18559923,18563362,18570890,18572386,18577518,18593910,18617556,18624398,18632853,18644434,18660489,18667434,18682391,18688042,18691388,18692180,18694962,18703508,18710790,18711316,18715846,18755896,18760861,18771677,18787043,18787400,18794356,18830271,18853184,18854243,18854640,18949384,18981248,18983981,18986987,19008312,19015316,19020743,19032445,19035465,19058874,19060905,19082454,19091959,19097033,19116345,19147502,19147767,19153083,19154323,19158277,19160418,19164129,19164283,19167335,19184415,19197339,19199380,19206162,19242545,19266047,19298651,19319745,19328461,19363666,19366876,19404844,19407222,19414528,19418584,19426868,19428994,19445727,19447520,19453261,19455469,19457236,19477952,19494114,19502238,19502590,19543489,19565474,19575782,19588500,19589780,19593445,19597469,19608729,19610261,19619936,19622906,19631608,19632304,19643177,19649722,19651986,19656390,19664780,19666073,19672022,19676104,19684019,19686845,19697705,19713532,19723095,19729990,19751964,19776005,19777442,19782465,19802003,19805545,19808666,19815047,19816090,19816934,19816936,19819966,19822148,19823867,19828458,19833733,19834610,19835659,19843478,19847302,19855431,19858308,19861416,19874574,19892016,19895547,19910486,19910580,19917255,19917706,19919532,19926313,19930715,19956840,20009539,20016498,20018936,20019835,20028985,20038816,20056088,20069553,20072648,20074451,20074637,20074640,20075392,20087064,20097574,20102637,20103886,20123980,20126471,20126615,20155832,20164223,20167130,20174585,20179103,20180987,20189953,20190820,20201065,20203690,20225236,20231899,20232314,20232315,20307589,20335309,20336759,20347885,20351270,20358251,20359813,20371703,20385094,20386571,20402410,20404718,20406097,20432452,20451919,20453075,20455999,20460375,20463007,20463008,20464500,20483734,20490331,20493910,20501673,20506264,20512084,20519144,20538278,20566577,20616308,20622900,20637859,20664595,20671117,20671123,20680465,20693286,20701626,20716207,20726858,20729213,20731749,20735357,20735841,20736304,20737958,20811691,20811717,20823131,20823133,20829350,20837468,20839920,20840867,20842205,20849923,20853849,20868224,20889506,20889557,21029458,21057728,21070506,21071439,21076047,21079800,21084381,21123621,21126445,21135229,21147777,21150201,21152870,21159167,21172820,21185392,21187340,21199725,21209852,21212994,21228323,21262199,21262770,21270289,21273059,21278199,21285250,21293101,21321112,21325048,21335558,21349701,21354279,21368226,21370247,21378313,21413023,21423810,21444628,21448845,21454500,21454579,21474332,21474333,21483469,21487005,21520151,21531765,21537329,21541441,21551235,21574189,21606674,21607585,21625939,21635820,21645924,21669399,21675959,21687944,21708241,21713404,21730054,21730285,21732279,21742938,21747041,21750416,21752354,21760921,21764057,21765462,21768093,21768115,21772273,21778192,21803177,21816898,21821233,21833774,21840940,21852536,21871886,21873423,21873429,21875946,21878648,21899882,21900206,21908610,21910869,21914806,21917714,21925842,21952366,21959954,21960346,21968647,21989417,22009749,22024154,22025613,22027397,22028271,22028468,22039050,22039051,22052014,22076613,22076920,22090124,22094458,22117074,22123847,22147898,22158075,22162761,22171261,22174934,22178882,22222560,22229442,22238304,22265030,22277029,22293503,22344067,22344606,22362758,22370345,22384111,22388352,22393163,22396784,22406505,22407921,22465663,22479424,22487967,22502979,22504224,22543708,22551942,22553998,22556124,22560877,22562654,22563495,22563497,22564243,22574813,22593617,22610905,22672288,22696230,22702503,22712802,22722337,22735594,22796164,22808094,22808266,22828925,22837689,22848708,22865467,22866973,22869729,22898922,22902213,22904195,22914360,22914643,22917644,22927430,22935974,22937208,22939629,22955283,22955917,22990118,22995914,23012423,23024368,23076151,23088735,23098854,23166842,23174997,23222305,23247634,23258237,23265704,23274199,23306155,23317503,23319595,23332156,23341459,23349307,23357054,23360766,23376485,23383273,23397142,23408424,23424616,23430108,23441482,23449627,23452857,23455179,23457635,23468892,23516513,23538858,23549785,23555755,23555914,23558220,23569008,23576434,23585396,23589880,23601559,23602568,23613227,23615537,23618859,23620784,23621408,23621870,23640488,23644655,23645677,23651922,23671702,23677697,23684072,23698777,23709326,23742646,23754287,23776205,23806683,23806693,23812726,23812841,23827636,23847209,23867452,23922976,23966319,23982477,23986795,24040019,24074900,24089523,24119769,24121020,24135036,24161842,24164897,24166600,24183461,24199952,24204846,24239461,24252614,24269383,24291038,24331979,24332066,24342355,24345643,24365237,24370825,24371145,24384722,24397597,24409324,24418364,24434142,24469921,24488174,24493589,24501087,24530396,24565681,24578133,24586397,24587385,24606918,24619413,24623414,24651445,24657322,24657659,24677094,24682903,24706358,24714552,24716848,24722188,24768991,24780446,24788939,24789460,24818995,24825908,24874739,24966925,24966948,25016365,25048004,25056061,25064159,25066297,25085753,25091805,25108429,25118288,25120769,25121610,25141921,25142507,25164676,25167778,25187541,25188412,25214430,25217205,25241249,25241253,25241761,25253956,25267105,25270024,25319474,25341684,25398317,25414256,25449334,25497010,25515236,25561793,25596700,25605020,25622783,25647783,25652124,25655003,25675421,25693804,25697727,25704763,25713071,25738359,25748447,25753158,25770213,25780035,25796184,25803100,25816226,25816245,25846811,25852190,25937083,25943894,25962735,25963833,26004135,26041847,26044620,26047699,26051103,26054744,26096876,26182292,26186194,26247533,26253279,26324936,26344197,26408092,26496610,26514924,26574555,26612919	15		NP_001035145.1|MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSPAAVGLGAGEQGGT,NP_001103361.1|MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPGVLEAP,NP_002737.2|MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPGVLEAP
39	PRKAA1	5562	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	AMPK|AMPKa1	human	NM_006251.5,NM_206907.3,XM_006714482.1	NP_006242.5,NP_996790.3,XP_006714545.1	NC_000005.10,NC_018916.2,NT_006576.17,NW_004929321.1	Q13131	Cytoplasm. Nucleus.	NULL			Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2. In response to nutrient limitation, promotes autophagy by phosphorylating and activating ATG1/ULK1. AMPK also acts as a regulator of circadian rhythm by mediating phosphorylation of CRY1, leading to destabilize it. May regulate the Wnt signaling pathway by phosphorylating CTNNB1, leading to stabilize it. Also has tau-protein kinase activity: in response to amyloid beta A4 protein (APP) exposure, activated by CAMKK2, leading to phosphorylation of MAPT/TAU; however the relevance of such data remains unclear in vivo. Also phosphorylates CFTR, EEF2K, KLC1, NOS3 and SLC12A1. {ECO:0000269|PubMed:11518699, ECO:0000269|PubMed:11554766, ECO:0000269|PubMed:12519745, ECO:0000269|PubMed:14651849, ECO:0000269|PubMed:15866171, ECO:0000269|PubMed:17486097, ECO:0000269|PubMed:17711846, ECO:0000269|PubMed:18184930, ECO:0000269|PubMed:18439900, ECO:0000269|PubMed:20074060, ECO:0000269|PubMed:20160076, ECO:0000269|PubMed:21205641}.	Hs.43322	1322130,2900138,7907095,8094892,8163463,8557660,8621713,8626596,8663446,8910387,9091312,9224708,9710607,9845345,9857077,10698692,10760274,10862786,11042152,11052978,11165240,11171059,11500364,11546797,11903059,11913976,11971957,11997383,12091379,12194824,12368907,12391032,12477932,12788940,12791703,12847291,12853467,12869384,12890675,14557259,14651849,14702039,14709557,14970221,14976552,14985344,14985505,15024086,15261145,15485651,15489334,15866171,16054041,16054095,16306228,16344560,16405649,16466905,16806233,16912160,17028174,17088252,17584647,18195011,18276112,18303014,18347656,18359290,18403135,18439900,18480843,18614941,18663353,18674809,18801964,18836454,18950855,18976975,18996102,19020741,19049348,19050283,19138981,19197243,19211918,19322201,19442239,19491292,19502591,19556893,19616115,19720090,19723093,19723094,19723101,19723105,19728147,19887561,19913121,19914239,19923924,19948975,19966861,20080969,20103647,20167678,20170185,20217115,20368287,20368732,20392842,20421294,20462511,20538596,20562859,20564492,20602615,20622004,20628086,20660302,20682687,20801214,20821366,20861072,20876741,21048031,21072212,21079763,21088205,21209024,21232561,21344388,21416543,21432774,21474997,21516116,21567395,21651489,21670147,21678424,21728993,21768291,21775054,21807092,21892142,21909354,21988832,21994947,22007913,22012985,22021095,22037551,22065577,22212710,22363791,22378745,22406815,22419736,22434430,22462548,22480519,22553202,22564965,22607554,22674476,22688514,22815988,22833096,22869372,22897928,22935535,22939624,22939629,22988252,23000302,23022380,23171948,23221389,23228943,23291726,23306156,23324179,23367447,23376776,23417417,23418352,23453806,23455922,23463002,23475945,23506848,23589839,23592276,23602568,23625915,23648710,23671028,23677989,23685869,23712032,23716691,23723070,23728343,23778007,23800577,23819460,23861218,23878245,23883584,23899558,23904275,23963659,23982477,24018441,24047437,24055274,24072697,24080159,24095280,24104889,24186207,24190973,24371122,24395629,24414799,24419061,24441100,24472739,24491542,24561578,24619908,24655923,24700636,24711643,24722188,24770722,24797263,24799027,24871657,24916949,24925061,24955726,24988326,25017332,25024613,25025067,25047736,25122135,25151490,25225183,25256353,25330949,25348630,25356873,25362209,25367309,25404641,25412657,25416956,25425646,25484082,25556665,25586669,25595658,25632961,25651975,25656579,25659498,25679763,25686248,25687571,25703587,25727016,25840010,25846811,25852190,25858560,25874865,25902870,25921289,25933205,25937278,25955819,25963833,25980607,26029847,26041108,26121488,26124005,26143491,26186194,26196392,26198640,26232429,26236947,26276392,26322680,26330165,26344197,26427441,26439621,26479318,26496610,26638075,26876938	15		NP_006242.5|MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ,NP_996790.3|MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ,XP_006714545.1|MLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
39	PRKAA2	5563	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	human	NM_006252.3	NP_006243.2	NC_000001.11,NC_018912.2,NT_032977.10,NW_004929290.1	P54646	Cytoplasm.  Nucleus.	NULL			Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. Involved in insulin receptor/INSR internalization (PubMed:25687571). AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2. In response to nutrient limitation, promotes autophagy by phosphorylating and activating ATG1/ULK1. AMPK also acts as a regulator of circadian rhythm by mediating phosphorylation of CRY1, leading to destabilize it. May regulate the Wnt signaling pathway by phosphorylating CTNNB1, leading to stabilize it. Also phosphorylates CFTR, EEF2K, KLC1, NOS3 and SLC12A1. Plays an important role in the differential regulation of pro-autophagy (composed of PIK3C3, BECN1, PIK3R4 and UVRAG or ATG14) and non-autophagy (composed of PIK3C3, BECN1 and PIK3R4) complexes, in response to glucose starvation. Can inhibit the non-autophagy complex by phosphorylating PIK3C3 and can activate the pro-autophagy complex by phosphorylating BECN1 (By similarity). {ECO:0000250|UniProtKB:Q8BRK8, ECO:0000269|PubMed:11518699, ECO:0000269|PubMed:11554766, ECO:0000269|PubMed:12519745, ECO:0000269|PubMed:14651849, ECO:0000269|PubMed:15866171, ECO:0000269|PubMed:17486097, ECO:0000269|PubMed:17711846, ECO:0000269|PubMed:18184930, ECO:0000269|PubMed:20074060, ECO:0000269|PubMed:20160076, ECO:0000269|PubMed:21205641, ECO:0000269|PubMed:25687571, ECO:0000269|PubMed:7959015}.	Hs.437039	1322130,1365882,1536860,2900138,7959015,7988703,8889548,9148944,9224708,10642499,10698692,10760274,11052978,11171059,11257506,11389854,11500364,11797013,12067722,12091379,12391032,12413941,12427743,12444247,12456889,12477932,12511592,12519745,12663462,12740371,12788940,12847291,12853467,12941758,14532170,14613924,14651849,14709557,14729328,14742438,14985344,14985505,15024086,15058305,15060529,15231718,15297373,15371448,15489334,15572372,15640157,16054041,16054095,16054096,16275868,16344560,16483872,16505254,16518831,16567511,16598851,16624523,16670154,16710414,16801347,16984726,17012231,17179156,17950019,18029386,18195011,18439900,18614941,18674809,18801964,18836454,18974883,18996102,19170765,19434633,19440859,19470831,19502591,19528236,19574280,19616115,19720090,19720831,19723084,19728147,19836452,19913121,19948975,20124121,20167927,20217115,20392842,20558612,20562859,20602615,20628086,20647423,20682687,20801214,20821366,20876741,21209024,21344388,21432774,21516116,21543851,21651489,21673972,21825219,22137581,22212710,22286170,22305490,22561688,22728651,22797923,22897928,22939624,23000302,23293026,23396962,23476055,23723070,24414799,24722188,25126726,25184681,25241761,25416956,25590814,25687571,25799226,25840010,25846811,25858560,26108355,26186194,26344197,26351140,26427488,26496610,26876938	15		NP_006243.2|MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFFEMCASLITTLAR
39	VPS15	852394	Serine/threonine-protein kinase VPS15		GRD8|VAC4|VPL19|VPS40|VPT15	baker's yeast	NM_001178445.2	NP_009655.2	NC_001134.8	P22219	NULL	NULL			Serine/threonine-protein kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I. This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure. Is also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II. This second complex is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes (probably through the synthesis of a specific pool of phosphatidylinositol 3-phosphate recruiting the retromer to the endosomes). By regulating VPS34 kinase activity, VPS15 appears to be essential for the efficient delivery of soluble hydrolases to the yeast vacuole. {ECO:0000269|PubMed:11157979, ECO:0000269|PubMed:12244127, ECO:0000269|PubMed:1756716, ECO:0000269|PubMed:1988155, ECO:0000269|PubMed:3062374, ECO:0000269|PubMed:7989323, ECO:0000269|PubMed:8387919, ECO:0000269|PubMed:8509446, ECO:0000269|PubMed:8649377}.		1493335,7721937,7813418,7989323,8387919,8649377,8849441,10637310,11157979,11689570,11805826,14576278,14731957,15551135,16421251,16429126,16487579,16554755,16729061,16823961,16839886,17565946,18467557,18676811,19445518,20489023,21070969,21121900,23335340,23390603,23904270,24165940,24307682,25163837	28		NP_009655.2|MGAQLSLVVQASPSIAIFSYIDVLEEVHYVSQLNSSRFLKTCKALDPNGEIVIKVFIKPKDQYSLRPFLQRIRAQSFKLGQLPHVLNYSKLIETNRAGYMIRQHLKNNLYDRLSLRPYLQDIELKFIAFQLLNALKDIHNLNIVHGDIKTENILVTSWNWCILTDFAAFIKPVYLPEDNPGEFLFYFDTSKRRTCYLAPERFNSKLYQDGKSNNGRLTKEMDIFSLGCVIAEIFAEGRPIFNLSQLFKYKSNSYDVNREFLMEEMNSTDLRNLVLDMIQLDPSKRLSCDELLNKYRGIFFPDYFYTFIYDYFRNLVTMTTSTPISDNTCTNSTLEDNVKLLDETTEKIYRDFSQICHCLDFPLIKDGGEIGSDPPILESYKIEIEISRFLNTNLYFPQNYHLVLQQFTKVSEKIKSVKEECALLFISYLSHSIRSIVSTATKLKNLELLAVFAQFVSDENKIDRVVPYFVCCFEDSDQDVQALSLLTLIQVLTSVRKLNQLNENIFVDYLLPRLKRLLISNRQNTNYLRIVFANCLSDLAIIINRFQEFTFAQHCNDNSMDNNTEIMESSTKYSAKLIQSVEDLTVSFLTDNDTYVKMALLQNILPLCKFFGRERTNDIILSHLITYLNDKDPALRVSLIQTISGISILLGTVTLEQYILPLLIQTITDSEELVVISVLQSLKSLFKTGLIRKKYYIDISKTTSPLLLHPNNWIRQFTLMIIIEIINKLSKAEVYCILYPIIRPFFEFDVEFNFKSMISCCKQPVSRSVYNLLCSWSVRASKSLFWKKIITNHVDSFGNNRIEFITKNYSSKNYGFNKRDTKSSSSLKGIKTSSTVYSHDNKEIPLTAEDRNWIDKFHIIGLTEKDIWKIVALRGYVIRTARVMAANPDFPYNNSNYRPLVQNSPPNLNLTNIMPRNIFFDVEFAEESTSEGQDSNLENQQIYKYDESEKDSNKLNINGSKQLSTVMDINGSLIFKNKSIATTTSNLKNVFVQLEPTSYHMHSPNHGLKDNANVKPERKVVVSNSYEGDVESIEKFLSTFKILPPLRDYKEFGPIQEIVRSPNMGNLRGKLIATLMENEPNSITSSAVSPGETPYLITGSDQGVIKIWNLKEIIVGEVYSSSLTYDCSSTVTQITMIPNFDAFAVSSKDGQIIVLKVNHYQQESEVKFLNCECIRKINLKNFGKNEYAVRMRAFVNEEKSLLVALTNLSRVIIFDIRTLERLQIIENSPRHGAVSSICIDEECCVLILGTTRGIIDIWDIRFNVLIRSWSFGDHAPITHVEVCQFYGKNSVIVVGGSSKTFLTIWNFVKGHCQYAFINSDEQPSMEHFLPIEKGLEELNFCGIRSLNALSTISVSNDKILLTDEATSSIVMFSLNELSSSKAVISPSRFSDVFIPTQVTANLTMLLRKMKRTSTHSVDDSLYHHDIINSISTCEVDETPLLVACDNSGLIGIFQ
39	VOLCADRAFT_120976	9615735				volvox	XM_002951700.1	XP_002951746.1	NW_003307568.1	D8TZ15	NULL	NULL					20616280	81		XP_002951746.1|MPTNTVIPSPRRELDEALITLPGGTRRNKSSVPAYANAFKGVSRQGRRAETQQVPVHSGASQPLDIQYDMVPGVKLAWAGPASGTYSTTGFGSSPKKYTSQLVGRVSPHYAGTPALQQTMSTPAGNQDQLHLPEIANGNSHSAAHQQGSFRGSNYALPTFQSWTPGTSTPGTASHARRALPYVSTNTSSLAKPLTVQYHPVLRSPSLGPGPGSPYTQPVATASAVAAGPRGTPQRPATDQGSPAQQAAGGVGPGEATRLYPRTAYGGQPHRLPHTPPEVAAEVARLRHAQELDGVIYGIRNELIQAAAPRLDPPVKSKFLQLYEDPNRPLAKLNPKQLLGEVAPSSQHHRRHRPHAIATDKPEVSSDGRPPSPMASSSRSPMYERRLRPLPTDIQEDAAAAQSAADMGDRADNQEIDALPNVHLRPPELPGEAGMRSGHDQGIGAEAEEETESPDRSTPRSSLIDREDTTLTMADFRALSDGGLSVALATAGEGTVGTEGVEQLGAAAEDVAPADGQAAGPQEYGQQQDGSVPPPVILAPSDEAAGASLQGAPEAGVPDQQLDEVLEQAQPRPPAAGPSTEVTAETCPEPAALEYMAGPLPSSDVGVTVQAGAPECAGEAEPESGDAAVPESTPKEDMDLLQDAGGTSSLDRVAGAPSAMPEVCKMDEDGAELGSGDAAKEPESQAAVQAPEIAVVPQGDGDEASPTVSGTGPTDAQEPEGAAAESRQEATADVADLEGAQAGAELNPSGSSECQPLESSETMAISASEATTAADAFVYSLPPGVTPEMARASAVCIQTHARGYQARRRMAVMRKEREAVKAQPEQVLQPEILPSPSTSLTKSEYELPQGVTPEMARAAIVRIQSHARGYFARRHVAELRRGREAGQAALATAVTAATTRKLEGYELKEGVSVEVAEAAAIRVQAHMRGHLARRRVRHMRAELSPSAEPASEPEQEASRGAATGEGPAEEDTTLREQGEAVSNRAGATEPAQPPVASEPEELTIDALKAALDEEQQDADAEAAAALSDAVAEEPAMLDMSDPAAVAAAAAKSAIRLLEDGSYGLDGVVDTTAAVDQTAAEASMARLAASSARTSAMFQGAGAEMRFSDDEASALELIDNLDGLLQGDDEAAAAAAAVAAAAAPADGEMVSISADGVSEPQALGTGGSGGGIAGAYGMVMKCKVRGTEPVQWVAIKEFKIDDNDPDAEDVKRTSLREVAVLEALQHPHVVGFVDKFMVGDRLFIVMEFLPCNLLELLEAQPGGMDRDAVRLIMFQLCSAIAFIHRKGMVYRDIKPENLLVDEHGTVKLCDFGFARYLPSGPSSHLTDYVATRWYRAPELLLGPPYRDALGKHVQYMYGPPVDMWAVGCLMGELLDGEPLFAGDSDLDQLYRVQQILGPMAPSHQYMFYANPHNTGIVFNIKQPMTLGARYRGKVSDVELSFMLGLLEMDPDKRLTGEQCLQHPYLVDLATAANAATTPSPSDSIVATSTNLSVDDGGSGGGDARFPAPLATGGDAGAGPQRGLSKLHANDNGHVVIVEGEVDDEEERGMAGGMAAVKSMSALAEVAAAVSEIEPLDEA
39	VOLCADRAFT_88093	9620582				volvox	XM_002947772.1	XP_002947818.1	NW_003307550.1	D8TN22	NULL	NULL					20616280	81		XP_002947818.1|MQLESASQPPPAELSTQPAGSESGDPPPLHRLFVGSVPRTAVEATLREYFEQCGVVRDLAVLRDRTSGKSRGCAFVSYLTLEEAEAAIQKFDRQLMLPGSQTPLEVRFAKNHSYVQAGEGPSGNRQIFFSRVPLTLKVCHHVAYEEDEILSLFLAYGEVETINVFKCRRSGRSKGCGFIEMRTREAAIAAMENLDERHVFDSTGTAISVRWADPDLQQRKKKAMDDANAENRMLFFAKVLRSTTEDDVRRLFSRFGKVYDINLFRAFQGAPTTKGCGLVTMSQHSDAVAAIAALDGIHVWEGMDCPMVVKWMDTALQRRRREQHLANIRQTPLPSSSIGALLGGQGPPPDPQQQQPQQQQQQQQQQQQQQQQQEQQEHRNQQQQQLSYQTVQHQHHQQHQQHQHQQHQHQHQHHQHHQQQLQTVIQLGAQPARVASASTSGGGAVGPGAGLTIVAEPPPAGHLQPPAVAAAHPPLGNNSGAGGGGGGGGGLIADLTVFPAADSAGGPPLELPPPGCNPDVVKLFIGNIPRGCTEKHLLALFQSIGKVVELVIMYDKVTREPKGSAFVWYATREDAERAILQFNLRPVFPDPSGAQDRPLVVRKAKARSSRMVVSAASMYAAATTLGQAAPLGAMPYTQRFVNVGGDGGAGSAGSSGLTVLSLPAAMEGLQIVDGSALGAGIGASMGVNMSVGVSGAPAQVPGAAVAAGTAAGPHPGLMHAGQVPVVGGGGGGGGGGGDGSRMGAGGHGRGMMGMVALAPSGAMAAGLYDAYGTGEHLLADFGTAAVLPANQTASVSAASGGAGGSSGGGYAVLLPSATGSNQWDAAAAATAASIALTHSQLQSLNQHLYGVQAVSGAALQLAASGPGLIQLYMSGQPIPHWPQLASCTVTARLTLPPFPGGGRFLKTLLCLHDSGGLVVVKVYFKRPDTAAGGLEPYKQQLTAIRYFWQESQYVGYLVRQHLAQNLYDRLSTRPFMSKLEKRWVAFQLLLAAAQIHNRGVVHGDIKSENVLMSSWSWVFLADFAAGLKPAALPADNPAEYSFFFDTGGRRRAYIAPERFFSSDSKPRTTSLTPEMALMDSEPRVVCDALRKRSMLSAAAKVVPLLRHESPVVRGSAVALVAAAAGHLPLADVFAQLAVLVKPYLRRMPPLLTDQQLVADCLMSHGAAETLSAARDKLAAPLRCGAAAAAAAASSGTHPSPSSSTSLRMAPEPPRLGGGDGGCGGGPADSGEVSFQGYPLLEGLCGAEDLGDLFLRPAAPLYTYDLSMDPSAAATAALAAAGAEGTGGAAAAAAAAIAAATATTGGGGAAAAPAAASAAAAVPGPGLSSHAAALATLCGRLSSLEPRVAVLAERLAREPMGVDPLERQQLERLAGLLARLRGDEGSDVRGAAARDTWRLVSLSQRGPPPLTSAAGPIGAGGGGGGAGGGLLGAAVQHGDYFSVSGGPFTSDSTSPHLLWGADRGDGAGAGSAGGGGGGGGGGGGGGGGGGWWRPRGVLVGHLAEHRRGVTRLAVGAGGCFLASASADETVKVWDLRRLERDVAFHSRLTYAAQTGRITALCCCGGPWSTPGGEGGAPWSSGTTVASGSSSGSLHLWRPEYTTRQGGVPDKYTGVVAVRQLSPGQGAILTVEPWGPHLLLYVTQRGGVTAWDTRTQRDAWVLPCAPAHGLPEHLLADPSQSASWLMTGGAGSSRGYVCLWDVRFQQSVHGEAGLWDVVSGRCRQVLRCLGPMEAEAAAAAATVPAALMPQPSPPSPHRVPSSTGGTAGTCTGTAGPGGISGTTTSTTGSGLEHAAVQPRTAGARCLLSLQGGALLWGGSDAAVRYWDTCRPAGSYAVCGPLWPGDSLSDGTAASGLSVPEYRYKYLTRAVGDVAVCEELCLLDNSASRLTESCHELRDRKSVTMSNHIAVLHAYAAVRTKNVLLAQPQVRVNDQAHADAVTALAVADPPGSSRLLLTASRDGVIKAWK
40	UVRAG	7405	UV radiation resistance-associated gene protein	UVRAG	DHTX|VPS38|p63	human	NM_003369.3,XM_006718674.2,XM_006718675.2,XM_011545226.1,XM_011545227.1,XM_011545228.1,XR_950027.1	NP_003360.2,XP_006718737.1,XP_006718738.1,XP_011543528.1,XP_011543529.1,XP_011543530.1	NC_000011.10,NC_018922.2,NG_046930.1,NT_167190.2,NW_004929380.1	Q9P2Y5	Late endosome. Lysosome.  Early endosome. Endoplasmic reticulum.  Midbody.  Chromosome, centromere.	NULL			Involved in maintaining chromosomal stability. Promotes DNA double-strand break (DSB) repair by association with DNA- dependent protein kinase complex DNA-PK and activating it in non- homologous end joining (NHEJ) (PubMed:22542840). Required for centrosome stability and proper chromosome segregation (PubMed:22542840). {ECO:0000269|PubMed:22542840}.	Hs.202470	2332174,8125298,9169138,9533029,10798355,12477932,12928850,14702039,14737099,16344560,16799551,17106237,17891140,18495205,18552835,18641390,18843052,19050071,19270696,19608861,20163458,20379614,20562859,20643123,20724836,21062745,21118109,21241894,21597469,21606679,22081109,22314358,22354037,22493499,22542840,23200933,23878393,23954414,24034250,24056303,24550300,24554770,24785657,24849286,24882360,24956373,24980960,25490155,25533187,25807108,25906440,26139536,26234763,26496610,26673895	15		NP_003360.2|MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHTSSAIPVPKRQSSIFGGADVGFSGGIPSPDKGHRKRASSENERLQYKTPPPSYNSALAQPVTTVPSMGETERKITSLSSSLDTSLDFSKENKKKGEDLVGSLNGGHANVHPSQEQGEALSGHRATVNGTLLPSEQAGSASVQLPGEFHPVSEAELCCTVEQAEEIIGLEATGFASGDQLEAFNCIPVDSAVAVECDEQVLGEFEEFSRRIYALNENVSSFRRPRRSSDK,XP_006718737.1|MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRKQMVILRDTVKGSEEQTDENH,XP_006718738.1|MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLQESSPLTVSGP,XP_011543528.1|MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCIKPQMSCFQFGAKPSWKRQPLTGNGCDRHHTSSAIPVPKRQSSIFGGADVGFSGGIPSPDKGHRKRASSENERLQYKTPPPSYNSALAQPVTTVPSMGETERKITSLSSSLDTSLDFSKENKKKGEDLVGSLNGGHANVHPSQEQGEALSGHRATVNGTLLPSEQAGSASVQLPGEFHPVSEAELCCTVEQAEEIIGLEATGFASGDQLEAFNCIPVDSAVAVECDEQVLGEFEEFSRRIYALNENVSSFRRPRRSSDK,XP_011543529.1|MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRICIRLDFLTKQHMVTMSAEDNVRLQLASIKLDIAKQTCKNVKQCHSSH,XP_011543530.1|MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQSFSVPLK
40	Uvrag	78610	UV radiation resistance associated protein	Uvrag	9530039D02Rik|AI648770|BB124205|Uvrag1|Uvragl	mouse	NM_178635.3,XM_006508349.2	NP_848750.3,XP_006508412.1	AC_000029.1,NC_000073.6,NT_039433.8,NW_001030877.1	Q8K245	Late endosome.  Lysosome.  Early endosome.  Endoplasmic reticulum.  Midbody.  Chromosome, centromere.	NULL			Involved in maintaining chromosomal stability. Promotes DNA double-strand break (DSB) repair by association with DNA- dependent protein kinase complex DNA-PK and activating it in non- homologous end joining (NHEJ). Required for centrosome stability and proper chromosome segregation (By similarity). {ECO:0000250|UniProtKB:Q9P2Y5}.	Mm.323072	9169138,10349636,10798355,10922068,11042159,11076861,11217851,12466851,12477932,12520002,12904583,14610273,15782199,16096065,16141072,16141073,17891140,18799693,18843052,21267068,21606679,22493499,22542840,24081163,24550300,25275521,25533187,25583492,25917095,25946189,26139536,26590968	19		NP_848750.3|MSSCASLGGPVPLPPPGPSAALTSGAPARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCDNEKIFKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAFQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPCEHKGHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRLGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFSTEHGKLQLQKDSLSELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNENKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISNAIPVPKRQSSTFGGADGGFSAGIPSPDKVHRKRASSENERLQYKTPPPSYNSALTQPGVAMPTSGDSERKVAPLSSSLDTSLDFSKENKKAGVDLGSSVSGDHGNSDSGQEQGEALPGHLAAVNGTALPSEQAGPAGTLLPGSCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK,XP_006508412.1|MWSCRLSSGVSDISGTSLLGTLLIEMAISFWIPTSLFICVIMRKSLKNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAFQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPCEHKGHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRLGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFSTEHGKLQLQKDSLSELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNENKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISNAIPVPKRQSSTFGGADGGFSAGIPSPDKVHRKRASSENERLQYKTPPPSYNSALTQPGVAMPTSGDSERKVAPLSSSLDTSLDFSKENKKAGVDLGSSVSGDHGNSDSGQEQGEALPGHLAAVNGTALPSEQAGPAGTLLPGSCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK
41	SH3GLB1	51100		SH3GLB1	Bif-1|CGI-61|PPP1R70|dJ612B15.2	human	NM_001206651.1,NM_001206652.1,NM_001206653.1,NM_016009.4,XM_006710672.2,XM_006710673.2,XM_011541538.1	NP_001193580.1,NP_001193581.1,NP_001193582.1,NP_057093.1,XP_006710735.1,XP_006710736.1,XP_011539840.1	NC_000001.11,NC_018912.2,NG_030018.1,NT_032977.10,NW_004929290.1	A0A087WW40,Q9Y371	Cytoplasm. Golgi apparatus membrane.	NULL				Hs.136309	8125298,9455484,10531379,10810093,11161816,11259440,11384986,11431473,11894096,12456676,12477932,14702039,14704270,15452144,15489334,15978591,16227588,16344560,16374509,16696976,16710414,16763557,16916719,17891140,18029348,18474606,18752120,18824435,18833585,19074440,19125733,19132989,19341794,19805544,20159967,20562859,20643123,21068542,21283040,21499257,21832049,21988832,22785202,22863883,23376485,23414517,23429496,24056303,24270810,25416956,25619828,25981964,26186194,26344197,26496610,26638075	15		NP_001193580.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,NP_001193581.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,NP_001193582.1|MIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,NP_057093.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,XP_006710735.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,XP_006710736.1|MIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,XP_011539840.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN
41	Sh3glb1	54673	Endophilin-B1	Sh3glb1	AA409932|AI314629|AU015566|Bif-1|mKIAA0491	mouse	NM_001282037.1,NM_001282042.1,NM_019464.3,XM_006501716.2,XM_006501717.1,XM_006501718.2	NP_001268966.1,NP_001268971.1,NP_062337.1,XP_006501779.1,XP_006501780.1,XP_006501781.1	AC_000025.1,NC_000069.6,NT_039240.8,NW_001030737.1	Q9JK48	Cytoplasm. Golgi apparatus membrane.	NULL			May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells (PubMed:17086176). May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts (PubMed:24523556). Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Isoform 2 acts antiapoptotic in neuronal cells; involved in maintenance of mitochondrial morphology and promotes neuronal viability (PubMed:24523556). {ECO:0000250|UniProtKB:Q9Y371, ECO:0000269|PubMed:17086176, ECO:0000269|PubMed:24523556}.	Mm.271775,Mm.440295	8889548,10349636,10725249,11042159,11076861,11217851,11259440,11604418,12456676,12466851,12477932,12520002,14610273,15031102,15368895,15489334,15782199,16075368,16141072,16141073,16227588,16602821,17381077,17891140,18474606,18806760,20671748,21068542,21499257,23055939,23287860,24220501,24523556,25619828,25981964	19		NP_001268966.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,NP_001268971.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGK,NP_062337.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN,XP_006501779.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGK,XP_006501780.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADE,XP_006501781.1|MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYALSNAIGPSAQASTGSLVITCPSNLNDLKESSNNRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN
42	DRAM2	128338		DRAM2	CORD21|PRO180|TMEM77|WWFQ154	human	NM_178454.4,XM_005270469.1,XM_005270470.1,XM_006710361.1,XM_006710362.1,XM_011540707.1,XM_011540708.1	NP_848549.3,XP_005270526.1,XP_005270527.1,XP_006710424.1,XP_006710425.1,XP_011539009.1,XP_011539010.1	NC_000001.11,NC_018912.2,NT_032977.10,NW_004929290.1	A0A024R0B7,Q6UX65	Lysosome membrane.	NULL				Hs.485606	12477932,12975309,15489334,16303743,16710414,18029348,19322201,19556885,19895784,20379614,21584698,22001757,25983245	15		NP_848549.3|MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI,XP_005270526.1|MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI,XP_005270527.1|MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI,XP_006710424.1|MLIWGNAKYCGSFIVNVYYLIKVKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI,XP_006710425.1|MLIWGNAKYCGSFIVNVYYLIKVKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI,XP_011539009.1|MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI,XP_011539010.1|MWWFQQGLSFLPSALVIWTSAAFIFSYITAVTLHHIDPALPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLGILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCSSVLHSGNFGTDLEQKLHWNPEDKGYVLHMITTAAEWSMSFSFFGFFLTYIRDFQKISLRVEANLHGLTLYDTAPCPINNERTRLLSRDI
43	AMBRA1	55626		AMBRA1	DCAF3|WDR94	human	NM_001267782.1,NM_001267783.1,NM_001300731.1,NM_017749.3,XM_005253009.2,XM_005253011.2,XM_005253014.2,XM_006718259.1,XM_006718260.1,XM_011520214.1,XM_	NP_001254711.1,NP_001254712.1,NP_001287660.1,NP_060219.2,XP_005253066.1,XP_005253068.1,XP_005253071.1,XP_006718322.1,XP_006718323.1,XP_011518516.1,XP_	NC_000011.10,NC_018922.2,NT_009237.19,NW_004929378.1	A0A075B6T1,Q9C0C7	Cytoplasmic vesicle, autophagosome.	NULL				Hs.654644	11214970,12107410,12477932,14702039,16344560,16949367,17589504,17603510,17622796,19295130,19615732,20360068,20562859,20694011,20711182,20921139,21145461,21358617,21753002,22190034,22441670,23069654,23429496,23524951,23551272,23954414,23974797,24337577,24587252,24879156,24980959,25127057,25215947,25438055,25499913,25515538,25803737,25891078,26086269,26186194,26496610	15		NP_001254711.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRSLALSPRLEYSGAILAHCKLRLPGSCHSPASASQVAGTTGAHHHARLIFAFLVEMEFHHVSQAGLELLTSGDLPTSASQSAGITGVSHRAWPRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,NP_001254712.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,NP_001287660.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTAECCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,NP_060219.2|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,XP_005253066.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTAECCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,XP_005253068.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTAECCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,XP_005253071.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,XP_006718322.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTAECCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,XP_006718323.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR,XP_011518516.1|MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRVLVAPYVQRHQITQQMSLNSVIGGREDTSFFG,XP_|
43	Ambra1	228361		Ambra1	2310079H06Rik|A130023A14|AA474864|AV021921|D030051N19Rik|mKIAA1736	mouse	NM_001080754.1,NM_172669.3,XM_006499252.1,XM_006499253.1	NP_001074223.1,NP_766257.3,XP_006499315.1,XP_006499316.1	AC_000024.1,NC_000068.7,NT_039207.8,NW_001030694.1	A2AH22	Cytoplasmic vesicle, autophagosome.	NULL				Mm.436667	10349636,11042159,11076861,11217851,12466851,12477932,12520002,12904583,14610273,14621295,15782199,16141072,16141073,17589504,17967808,18799693,20921139,21267068,21677750,21753002,22240590,22493499,23524951,23910655,24089209,25438055,25499913,25931117,26496610	19		NP_001074223.1|MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTRTVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVSTTFEGMPPSGNQLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEEPGAASSGPGEGEGSEYGGSGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELPQPALSSSSPVPIPVPLASNEGPTMHCNVTNNSHLPEGDGSNRGEAAGPSGEPQNR,NP_766257.3|MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTTVECCQHPGILCLCSRCAGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTRTVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVSTTFEGMPPSGNQLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEEPGAASSGPGEGEGSEYGGSGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELPQPALSSSSPVPIPVPLASNEGPTMHCNVTNNSHLPEGDGSNRGEAAGPSGEPQNR,XP_006499315.1|MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTTVECCQHPGILCLCSRCAGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTRTVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVSTTFEGMPPSGNQLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEEPGAASSGPGEGEGSEYGGSGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELPQPALSSSSPVPIPVPLASNEGPTMHCNVTNNSHLPEGDGSNRGEAAGPSGEPQNR,XP_006499316.1|MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTRTVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVSTTFEGMPPSGNQLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVHSSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEEPGAASSGPGEGEGSEYGGSGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELPQPALSSSSPVPIPVPLASNEGPTMHCNVTNNSHLPEGDGSNRGEAAGPSGEPQNR
44	RB1CC1	9821	RB1-inducible coiled-coil protein 1	RB1CC1	ATG17|CC1|FIP200|PPP1R131	human	NM_001083617.1,NM_014781.4,XM_011517643.1,XM_011517644.1,XM_011517645.1,XM_011517646.1,XM_011517647.1,XM_011517648.1,XM_011517649.1,XM_011517650.1,XR_	NP_001077086.1,NP_055596.3,XP_011515945.1,XP_011515946.1,XP_011515947.1,XP_011515948.1,XP_011515949.1,XP_011515950.1,XP_011515951.1,XP_011515952.1	NC_000008.11,NC_018919.2,NG_015833.1,NT_008183.20,NW_004929339.1	Q8TDY2	Nucleus. Cytoplasm.  Cytoplasm, cytosol.  Preautophagosomal structure.	NULL			Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double- membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways. {ECO:0000250, ECO:0000269|PubMed:10769033, ECO:0000269|PubMed:12095676, ECO:0000269|PubMed:12163359, ECO:0000269|PubMed:12221124, ECO:0000269|PubMed:14533007, ECO:0000269|PubMed:21775823, ECO:0000269|PubMed:23262492}.	Hs.196102	7724523,9039502,10769033,11850849,12068296,12095676,12163359,12221124,12477932,14533007,15375585,15489334,15968549,16043512,16061648,16344560,16865226,17015619,17081983,17353931,17706618,17707572,17986458,18036779,18285457,18443221,18676680,18976975,19170196,19211835,19225151,19258318,19437535,19597335,19625176,19690328,19692168,19888451,20301425,20453000,20562859,20614030,21203526,21241894,21602932,21637919,21717524,21775823,21795712,21822266,21903422,21988832,22049074,22396748,22751121,23043107,23262492,23289756,23392225,23602568,23885119,23960084,24100292,24610824,24711643,24732589,24954904,25040165,25640309,25686248,26151896,26186194,26496610	15		NP_001077086.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,NP_055596.3|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011515945.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011515946.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKCSFITPKTAGHLFMQKSA,XP_011515947.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPASGASRRPWVLGKVMEKEYCQAKKCSFITPKTAGHLFMQKSA,XP_011515948.1|MAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011515949.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQRELFPTYPLRPVLYTNTKSDKYIKRRKYIFYNY,XP_011515950.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKRYQQFDHQCQYQQGEKGNTWCYYENSSDFTCPLNVFG,XP_011515951.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRPPAIPKTTFSTENDMEIKVEESLMMPAVFHTVASRTQLALEMYEVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSNYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRLDSLPEHEDSEKAEMKRSTELVLSPDMPRTTNESLLTSFPKSVEHVSPDTADAESGKEIRESCQSTVHQQDETTIDTKDGDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPRIIRPFIAECRQTIAKLDNQNMKAIKGLEDRLYALDQMIASCGRLVNEQKELAQGFLANQKRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVKIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKRLYEAEKSKRESFGKLFRKSFLRNRLFRGLDSWPPSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKRGNL,XP_011515952.1|MERDYMKQKNQKGNPLGNYLTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLSEQKASVSQTSPQSASSPRMESTAGITTTTSPRTPPPLTVQDPLCPAVCPLEELSPDSIDAHTFDFETIPHPNIEQTIHQVSLDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTNVCGKEDFGDHTSLNVQLERCRVVAQDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSMSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV
44	Rb1cc1	12421	RB1-inducible coiled-coil protein 1	Rb1cc1	2900055E04Rik|5930404L04Rik|Cc1|FIP200|LaXp180	mouse	NM_009826.4,XM_006495443.2,XM_011238338.1,XM_011238339.1,XM_011238340.1,XM_011238341.1,XM_011238342.1	NP_033956.2,XP_006495506.1,XP_011236640.1,XP_011236641.1,XP_011236642.1,XP_011236643.1,XP_011236644.1	AC_000023.1,NC_000067.6,NT_039169.8,NW_001030649.1	Q9ESK9	Nucleus. Cytoplasm, cytosol.  Cytoplasm.  Preautophagosomal structure.	NULL			Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a novel mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways (By similarity). Plays a role as a modulator of TGF-beta- signaling by restricting substrate specificity of rnf111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double- membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis. {ECO:0000250, ECO:0000269|PubMed:12095676, ECO:0000269|PubMed:15968549, ECO:0000269|PubMed:19258318, ECO:0000269|PubMed:19940130, ECO:0000269|PubMed:21088496, ECO:0000269|PubMed:21525242, ECO:0000269|PubMed:21795712, ECO:0000269|PubMed:21807966, ECO:0000269|PubMed:23285000, ECO:0000269|PubMed:23392225}.	Mm.293811	7724523,8889548,10349636,11042159,11076861,11207567,11217851,11850849,12095676,12465718,12466851,12477932,14610273,14691545,15375585,15968549,16043512,16141072,16141073,16865226,17015619,17706618,18039682,18285457,18443221,18799693,18981720,19106106,19211835,19258318,19940130,20716775,21220506,21267068,21525242,21677750,21764854,21795712,21807966,22049074,23392225,23402761,23537899,23542691,23633228,23637331,23685627,23960084,24185898,24266345,24449836,24591649,24741061,24923305,25052093,26075877	19		NP_033956.2|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_006495506.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011236640.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEHVCHHSVSMDSEDKMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011236641.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEHVCHHSVSMDSEDKMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011236642.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEHVCHHSVSMDSEDKMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011236643.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEHVCHHSVSMDSEDKMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPASGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV,XP_011236644.1|MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNPIFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLVHDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTRHSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTTNTSLVTSFHKSMEHVAPDPTGTERGKELRESCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSSFCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQTITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFDFETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLHFDLHL
45	ATG101	60673		ATG101	C12orf44	human	NM_001098673.1,NM_021934.4	NP_001092143.1,NP_068753.2	NC_000012.12,NC_018923.2,NT_029419.13,NW_004929384.1	A0A024R128,Q9BSB4	Cytoplasm. Preautophagosomal structure.	NULL				Hs.9911	12477932,14702039,15342556,16712791,19287211,19597335,20562859,21900206,21988832,23392225,23640897,24100292,25686248	15		NP_001092143.1|MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRRLIKDTLAL,NP_068753.2|MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRRLIKDTLAL
46	ZFYVE1	53349	Zinc finger FYVE domain-containing protein 1	ZFYVE1	DFCP1|PPP1R172|SR3|TAFF1|ZNFN2A1	human	NM_001281734.1,NM_001281735.1,NM_021260.3,NM_178441.2,XM_011536839.1,XR_943478.1	NP_001268663.1,NP_001268664.1,NP_067083.1,NP_848535.1,XP_011535141.1	NC_000014.9,NC_018925.2,NT_026437.13,NW_004929393.1	Q9HBF4	Golgi apparatus, Golgi stack.  Endoplasmicreticulum.	NULL				Hs.335106	10997877,11024279,11256955,11739631,11804589,12477932,12508121,14702039,15489334,15498874,16344560,19389623,19898463,21832049,21900206,22178386,22456507,23455425,25578879,26673895	15		NP_001268663.1|MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGEEVSVVPKTSASTDSPWMGLAKYAWSGRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL,NP_001268664.1|MAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL,NP_067083.1|MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL,NP_848535.1|MAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL,XP_011535141.1|MAHSSFFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGEEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL
46	Zfyve1	217695	Zinc finger FYVE domain-containing protein 1	Zfyve1	DFCP1|G630053K23|TAFF1|ZNFN2A1|mKIAA1589	mouse	NM_183154.3,XM_006515689.2,XM_006515690.2,XM_006515691.2,XM_006515692.2,XM_011244073.1	NP_898977.2,XP_006515752.1,XP_006515753.1,XP_006515754.1,XP_006515755.1,XP_011242375.1	AC_000034.1,NC_000078.6,NT_039551.8,NW_001030502.1	Q810J8	Golgi apparatus, Golgi stack. Endoplasmic reticulum.	NULL				Mm.59257	10349636,11042159,11076861,11217851,12466851,12477932,12904583,14610273,14621295,15489334,16141072,16141073,17967808,18799693,22456507,23455425,25876663	19		NP_898977.2|MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL,XP_006515752.1|MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL,XP_006515753.1|MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL,XP_006515754.1|MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL,XP_006515755.1|MAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL,XP_011242375.1|MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL
47	BCL2	596		BCL2	Bcl-2|PPP1R50	human	NM_000633.2,NM_000657.2,XM_011526135.1,XR_935246.1,XR_935247.1,XR_935248.1	NP_000624.2,NP_000648.2,XP_011524437.1	NC_000018.10,NC_018929.2,NG_009361.1,NT_010966.15,NW_004929411.1	A0A024R2B3,A0A024R2C4,P10415	Mitochondrion outer membrane.	NULL				Hs.150749	36599,1339299,1373874,1453000,1502141,1508712,1908951,2250705,2834197,2875799,3285301,3523487,3924412,7546744,7579350,7593193,7650367,7753817,7772249,7834748,7896880,7929424,7954800,8022822,8050499,8080725,8090743,8183370,8232588,8358790,8402618,8402648,8551385,8649841,8668206,8760290,8790371,8910675,8929532,8949945,9027314,9031086,9070836,9109491,9111042,9115213,9119086,9130713,9184696,9219694,9226175,9226228,9305631,9305851,9334338,9388232,9389483,9395403,9430630,9449720,9463381,9488477,9525867,9561195,9645350,9660918,9668078,9727491,9731710,9738012,9742125,9765397,9788433,9843949,9852076,9973195,10072505,10075695,10198631,10217402,10329560,10330179,10354271,10417825,10467396,10490827,10506221,10521466,10567572,10597216,10620603,10620799,10622714,10625696,10669763,10677502,10679027,10716992,10807576,10837489,10848600,10871848,10949025,11054413,11060313,11123279,11126360,11158204,11175251,11181702,11206074,11262395,11264898,11278245,11323417,11325850,11326318,11368354,11390485,11406564,11437653,11463391,11463392,11483855,11495898,11513873,11527400,11530860,11546872,11583631,11642719,11684014,11728179,11752215,11759059,11759062,11774038,11776759,11787859,11790116,11804283,11804688,11832478,11839683,11855781,11856759,11861644,11864421,11867266,11871856,11877091,11877266,11877309,11877669,11877670,11908736,11914580,11929874,11940482,11948397,11949842,11949843,11956602,11959101,11964319,11971816,11983915,11986946,11988841,11994280,11999565,12000759,12011972,12019168,12025227,12031912,12032828,12032841,12036852,12036886,12036888,12039864,12046064,12054739,12054916,12070027,12082633,12086670,12086875,12095980,12095993,12096338,12101183,12112824,12118096,12133494,12133517,12137781,12140755,12151395,12161031,12162425,12165497,12167335,12170763,12171774,12172977,12174951,12186923,12189556,12197229,12197771,12207028,12209154,12209955,12214154,12215338,12217802,12234263,12270344,12393707,12400004,12404120,12420213,12421819,12431997,12439925,12440815,12452037,12477721,12477729,12477932,12480939,12481899,12488548,12490308,12499093,12510149,12510191,12513829,12515824,12530303,12532420,12533044,12540563,12575534,12579337,12581249,12583439,12613529,12617962,12624108,12629413,12637332,12667443,12670866,12684626,12686415,12694817,12698366,12702730,12720100,12721288,12721767,12722479,12729794,12749011,12751031,12754350,12756585,12759537,12815463,12819863,12821128,12835724,12839682,12853473,12879322,12890751,12890867,12901880,12937123,12938158,12939460,12960134,12960340,12970736,13130506,14519627,14529662,14554083,14555646,14558950,14572466,14612291,14627346,14628086,14631373,14647416,14647426,14660675,14679209,14689061,14698203,14699151,14714449,14724650,14737118,14739602,14754534,14764541,14767525,14769789,14964781,14966123,14971737,14980220,14999286,15006356,15024706,15026553,15033793,15033825,15033827,15034060,15051039,15057274,15061204,15093750,15115329,15123638,15124764,15149157,15149158,15156398,15179054,15196944,15203866,15210690,15225643,15231068,15231831,15233914,15235941,15243561,15245329,15261486,15263017,15274378,15280201,15302859,15303767,15314290,15314639,15329319,15339676,15340216,15344336,15345651,15351796,15353294,15367432,15375594,15467428,15467450,15478112,15484294,15489334,15489891,15492114,15498929,15520201,15528355,15541642,15544840,15545228,15547950,15561778,15563082,15572421,15574335,15577328,15584904,15593417,15605273,15613488,15619620,15633216,15634885,15638363,15657349,15657350,15694340,15716988,15720412,15720419,15733859,15735709,15754411,15757646,15757977,15763593,15776018,15799693,15800682,15803126,15811121,15817479,15826766,15830715,15832179,15832769,15837573,15840562,15849194,15876860,15880952,15889622,15901672,15907209,15911345,15929186,15965276,15981087,15990872,16007339,16010987,16120388,16132718,16133992,16139338,16148027,16166262,16167175,16173075,16179260,16181427,16183855,16186627,16186795,16194898,16195370,16199534,16204228,16215670,16215945,16227396,16228292,16235026,16243795,16246184,16273250,16307838,16308474,16358373,16434970,16438077,16443602,16463650,16469847,16472763,16479062,16481323,16509771,16520895,16530191,16533178,16533807,16538384,16541314,16545683,16550596,16554306,16566921,16568081,16575548,16636671,16638854,16638864,16642033,16648655,16675913,16690525,16697956,16707568,16714000,16717086,16732934,16733517,16735440,16750039,16761743,16777355,16790527,16799010,16820876,16832704,16839413,16840204,16841088,16850164,16855163,16874461,16949642,16950491,16960146,16982461,16984978,16988783,16998187,17007374,17015762,17050165,17074584,17074758,17082179,17090549,17091766,17097560,17118768,17145812,17188136,17191123,17200714,17203183,17207023,17241114,17252199,17259174,17272502,17274640,17289999,17290286,17295204,17301078,17310847,17325632,17356300,17360176,17363905,17372162,17379544,17379601,17384650,17404013,17418785,17426248,17434928,17438366,17439414,17446862,17464868,17473827,17507655,17516030,17516614,17525735,17534194,17536310,17557568,17561354,17575222,17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47	BCL2L1	598		BCL2L1	BCL-XL/S|BCL2L|BCLX|Bcl-X|PPP1R52	human	NM_001191.3,NM_001317919.1,NM_001317920.1,NM_001317921.1,NM_001322239.1,NM_001322240.1,NM_001322242.1,NM_138578.2,NR_134257.1,XM_005260486.2,XM_005260	NP_001182.1,NP_001304848.1,NP_001304849.1,NP_001304850.1,NP_001309168.1,NP_001309169.1,NP_001309171.1,NP_612815.1,XP_005260543.1,XP_005260544.1,XP_011	NC_000020.11,NC_018931.2,NG_029002.1,NT_011362.11,NW_004929418.1	A0A0S2Z3C5,Q07817,Q5TE63	NULL	NULL				Hs.516966,Hs.732176	7540278,7644501,7650367,7834748,8358789,8596636,8692274,8929532,9020082,9027312,9027313,9111042,9130713,9153240,9184696,9192670,9305851,9326610,9334338,9372935,9388232,9389483,9393856,9430630,9435230,9488720,9525867,9539746,9660918,9675101,9727492,9731710,9742125,9765397,9824152,9843949,9973195,10049775,10075695,10085290,10195903,10198631,10217402,10330179,10365962,10446169,10467396,10467399,10620799,10625696,10679027,10713718,10716992,10737788,10802717,10807576,10837489,10891504,10949025,11044452,11054413,11060313,11077446,11123279,11126360,11175750,11206074,11278245,11279541,11283018,11342619,11423909,11437653,11463391,11463392,11483855,11494146,11574549,11583631,11696595,11714801,11733517,11739707,11742726,11756417,11780052,11788897,11801602,11832478,11859372,11883953,11911810,11941452,11964315,11965035,11971963,11994280,12000759,12011449,12025227,12046686,12070027,12079401,12108390,12115603,12137781,12161031,12186923,12198137,12204872,12209955,12214154,12244097,12372300,12381725,12387875,12439925,12477932,12510191,12515824,12553012,12579342,12592339,12594175,12637494,12667443,12721288,12738789,12767928,12783855,12810626,12815463,12853473,12855666,12901880,12937123,12963020,12969962,14502257,14520471,14573608,14596824,14625274,14631373,14656874,14656879,14668940,14735465,14739602,14752512,14764594,14960327,14963330,14980220,15006356,15030396,15031724,15034060,15077116,15079071,15110758,15124764,15131699,15156398,15179366,15231831,15292226,15292519,15323553,15353804,15375594,15385505,15459189,15459197,15477204,15489334,15574335,15625014,15625897,15637055,15638362,15638369,15653751,15657349,15657350,15694340,15694358,15705582,15721256,15722788,15725478,15733859,15767554,15770735,15782132,15827323,15837790,15870695,15901672,15961228,16048439,16052512,16077903,16081848,16085054,16085058,16148096,16151013,16189514,16192647,16204228,16253528,16260615,16282323,16368107,16403219,16492678,16509771,16572289,16572323,16603546,16608847,16631755,16632475,16650855,16684963,16697956,16723699,16773221,16790528,16794010,16810067,16815550,16835272,16850161,16928273,16959370,16983335,16998475,17046835,17110373,17209561,17227835,17237249,17272823,17274640,17289999,17301078,17311927,17369848,17384650,17404017,17418785,17428862,17439414,17446862,17457084,17492131,17519046,17525735,17534896,17633465,17652760,17657164,17659302,17673921,17699158,17803695,17873279,17880809,17893147,17911582,17923112,17923691,17927446,17942397,18051367,18069888,18079751,18088462,18171672,18182854,18196538,18216295,18220834,18250306,18262222,18285708,18299329,18309324,18342927,18428028,18494061,18511705,18534987,18543286,18566606,18568767,18580065,18590823,18594472,18609706,18628207,18636124,18641390,18718060,18719108,18768389,18775810,18786178,18806875,18813778,18818203,18820703,18835031,18843207,18974096,19008458,19020723,19043455,19049976,19060904,19064571,19074266,19074440,19165861,19180116,19199036,19211554,19212627,19219602,19220664,19236754,19242522,19317621,19336552,19395874,19397698,19427857,19427863,19439449,19459857,19467764,19475409,19520842,19530162,19567200,19573080,19587033,19634140,19667065,19670908,19692168,19713971,19723045,19763917,19767770,19773279,19797069,19820711,19834061,19838163,19878271,19883274,19916559,19917720,19948828,19955567,20010695,20045442,20048149,20051518,20063052,20080789,20090905,20100468,20106970,20140092,20178603,20192224,20203691,20213502,20223826,20308427,20331635,20347499,20363734,20400521,20453000,20468060,20507983,20541605,20554038,20580954,20581863,20603619,20628624,20661931,20673843,20728382,20803149,20818434,20855536,20858890,21033220,21041309,21080944,21081150,21148306,21173168,21187157,21199865,21203533,21226954,21256112,21277008,21292770,21320495,21339291,21367852,21396851,21399876,21424121,21454712,21458670,21516116,21527247,21533126,21567405,21589877,21639858,21656147,21659544,21669490,21671007,21674052,21674599,21726118,21840391,21852238,21854985,21856303,21863213,21887277,21900206,21952639,21971866,21980434,21988832,22009326,22084435,22098591,22099018,22119486,22127243,22138435,22141411,22158966,22160868,22197371,22211240,22213163,22219388,22235227,22240664,22267549,22354970,22393362,22403404,22433870,22440396,22440942,22454513,22464442,22486615,22515821,22516262,22522453,22552851,22589539,22609401,22617334,22627140,22670675,22685558,22686245,22705850,22729867,22732506,22797576,22884477,22892098,22898820,22933114,22949227,22960132,22987535,23013270,23028682,23051936,23055042,23064052,23079612,23091012,23171055,23243017,23245996,23275004,23292448,23333404,23369735,23382671,23392805,23442864,23449449,23475955,23519249,23562578,23573264,23670706,23680104,23708869,23749114,23756231,23798675,23802633,23812727,23823868,23828460,23887890,23908595,23954445,23960074,23977882,24038028,24050266,24055032,24091677,24116174,24217227,24217388,24286026,24297914,24313893,24339958,24443581,24474649,24491557,24508256,24514149,24523919,24614958,24621501,24621885,24650799,24808369,24814347,24907396,24922075,24982172,24999239,25025927,25060925,25084985,25092868,25110240,25126723,25225677,25241761,25270224,25296756,25299770,25318106,25324306,25333670,25343522,25371206,25416956,25429837,25473892,25522273,25590803,25661370,25683634,25684043,25726913,25731750,25773855,25844633,25862560,25875481,25876659,25965792,25975002,26054744,26186194,26215742,26245900,26396258,26401016,26496610,26556313,26710889,26871637	15		NP_001182.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_001304848.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_001304849.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_001304850.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_001309168.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_001309169.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_001309171.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,NP_612815.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,XP_005260543.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,XP_005260544.1|MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK,XP_011|
47	Bcl2	12043	Apoptosis regulator Bcl-2	Bcl2	AW986256|Bcl-2|C430015F12Rik|D630044D05Rik|D830018M01Rik	mouse	NM_009741.5,NM_177410.3	NP_033871.2,NP_803129.2	AC_000023.1,NC_000067.6,NT_078297.7,NW_001030662.1	P10417,Q6NTH7,Q8BQK4	NULL	NULL			Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). {ECO:0000269|PubMed:17418785}.	Mm.257460	1335956,1337029,1373874,1450512,1498330,1508712,1611911,1672292,1794054,1835668,1896073,1924327,1959134,1970800,2183011,2250704,2649247,2895697,3032455,3165083,7472523,7478538,7507474,7545760,7546744,7561683,7563251,7585606,7587091,7594564,7595537,7602121,7607090,7609638,7612233,7628407,7632929,7639335,7642473,7646485,7650367,7650488,7669664,7669718,7675327,7721348,7732571,7734031,7736574,7751019,7753802,7753817,7772249,7812968,7834747,7834748,7840250,7846127,7847793,7862455,7896880,7929424,7945396,7953633,7954800,7962121,8012109,8022822,8027571,8030757,8050499,8080725,8084613,8105477,8108419,8113673,8118099,8132207,8133891,8149910,8157699,8170972,8181070,8183579,8206089,8208546,8268655,8288247,8294493,8313913,8358176,8358790,8360476,8372353,8376932,8402909,8406486,8441607,8466531,8468048,8479747,8524870,8557033,8564847,8577388,8587122,8623928,8625820,8631771,8635454,8640868,8642244,8650001,8661050,8661724,8663032,8670887,8674410,8692941,8697804,8700551,8753880,8755480,8757609,8758925,8760259,8760267,8788039,8790367,8798441,8799155,8811108,8815872,8836552,8889548,8895385,8917732,8933760,8946914,8949945,8950980,8962163,9008714,9009190,9028316,9052834,9056714,9070836,9078436,9098922,9106670,9115213,9142988,9153592,9169087,9176392,9176486,9184696,9194558,9202146,9215624,9215625,9215626,9216067,9237103,9241272,9252127,9252128,9271117,9299161,9327729,9362445,9374413,9413174,9422522,9484776,9525867,9547242,9560217,9590129,9681465,9682022,9697835,9723184,9771644,9780150,9794553,9828132,9843949,9852076,9916699,9916985,9950951,9988219,9988222,10075839,10193316,10197582,10200490,10200548,10201940,10223192,10321489,10349636,10363969,10366444,10375669,10377054,10383617,10414973,10415149,10417825,10452843,10486519,10488913,10493738,10498879,10519417,10523863,10582606,10588741,10588868,10597216,10597263,10602483,10607745,10611317,10611509,10618441,10619357,10644554,10674380,10693874,10726970,10739651,10762311,10762322,10807576,10815637,10894153,10955330,11027399,11042159,11076861,11077442,11086988,11092819,11120788,11146504,11212255,11217851,11226327,11259262,11275690,11290297,11311799,11325830,11359801,11413198,11438662,11463391,11527400,11546872,11572983,11709185,11723074,11731234,11747371,11777964,11781239,11832424,11840165,11865975,11896583,11920569,11920715,11922619,11926897,11934474,11937580,11980919,11983915,12009762,12050152,12082633,12086670,12114718,12167626,12189556,12209154,12218115,12234259,12242151,12270125,12370314,12374983,12393617,12414660,12420306,12433687,12462415,12466851,12477932,12598723,12606450,12614028,12617961,12717433,12718432,12732662,12791942,12801416,12801933,12849704,12851714,12855558,12881529,12915712,12928432,12949911,14500638,14550262,14551195,14555646,14572898,14645573,14647416,14651853,14656881,14657025,14657380,14660795,14662332,14668867,14695177,14699151,14707049,14733915,14734712,14749373,14764669,14768056,14962910,15010700,15057274,15123655,15136728,15148390,15155612,15179559,15203215,15233914,15258617,15292044,15294893,15312804,15326356,15380515,15492043,15509702,15545599,15613488,15618488,15708565,15708569,15728354,15731004,15746559,15761494,15776018,15780994,15782199,15818405,15836427,15849194,15888023,15901735,15905539,15907209,15911345,15946936,15983387,16079159,16095731,16102793,16141072,16141073,16188096,16200198,16227588,16262630,16270868,16282979,16354545,16393138,16415685,16427619,16443792,16485035,16518721,16620920,16672320,16690745,16697956,16714293,16717086,16766264,16839884,16888403,16935937,16950491,16982684,16987237,17019806,17045827,17068116,17133361,17135264,17219413,17234957,17267035,17274640,17289999,17308993,17317859,17382885,17382917,17475835,17476283,17494993,17504973,17540004,17541981,17586682,17591857,17616686,17622798,17674769,17705137,17714451,17785775,17786945,17884794,17909078,17913397,17955375,17965419,18023519,18032675,18086008,18097009,18097449,18097759,18159948,18161062,18195012,18223655,18229451,18281291,18287559,18382684,18405886,18417716,18437159,18443228,18445590,18490895,18499746,18552208,18570871,18614015,18718527,18722365,18729219,18772134,18787044,18806761,18818203,18835031,18835033,18835564,18845789,18988889,18990690,19017967,19074266,19079363,19139267,19144853,19168699,19197937,19229877,19250983,19307306,19429009,19502415,19621384,19622370,19629484,19630211,19633419,19651893,19667115,19672954,19682497,19737977,19738028,19740330,19780757,19808650,19814688,19834489,19839062,19846553,19885953,19935657,20030922,20035012,20145039,20187704,20231687,20299524,20363911,20392256,20460269,20503275,20523125,20539308,20569988,20621101,20637280,20643953,20656893,20662604,20692344,20711984,20716950,20819940,20843830,20856227,20876285,20889974,20974940,21052840,21148799,21151042,21248291,21317312,21393866,21402911,21451108,21458954,21474673,21533046,21560315,21606168,21606958,21624358,21672382,21742968,21765887,21768356,21818117,21850221,21880664,21916141,21924257,21958558,21997189,22036586,22037186,22081075,22107967,22123611,22197342,22198238,22203953,22209676,22223437,22257939,22258505,22275372,22371349,22374434,22389723,22393362,22403281,22461702,22704985,22710123,22855610,22878411,22892563,22932141,22933114,23073173,23088454,23091012,23108914,23129176,23149744,23203923,23267016,23269245,23341540,23355742,23430084,23440261,23481305,23514933,23590664,23666531,23713735,23787700,23825125,23840878,23843527,23936461,24129924,24141421,24240096,24266926,24293136,24349082,24363325,24381169,24394664,24395794,24466179,24469320,24500693,24711453,24741061,24786774,24825007,24829923,24912196,24966955,24982181,25000291,25014217,25057207,25127920,25266628,25384217,25470948,25574476,25680182,25693418,25898913,25961032,26178579,26189065,26319553,26344567	19		NP_033871.2|MAQAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDADAAPLGAAPTPGIFSFQPESNPMPAVHRDMAARTSPLRPLVATAGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK,NP_803129.2|MAQAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDADAAPLGAAPTPGIFSFQPESNPMPAVHRDMAARTSPLRPLVATAGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWVGACLVE
48	GOPC	57120	Golgi-associated PDZ and coiled-coil motif-containing protein	GOPC	CAL|FIG|GOPC1|PIST|dJ94G16.2	human	NM_001017408.2,NM_020399.3	NP_001017408.1,NP_065132.1	NC_000006.12,NC_018917.2,NT_025741.16,NW_004929328.1	Q9HD26	Cytoplasm.  Golgi apparatus membrane.	NULL			Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes. {ECO:0000269|PubMed:11707463, ECO:0000269|PubMed:14570915, ECO:0000269|PubMed:15358775}.	Hs.191539	9843494,11162552,11384996,11520064,11707463,12149515,12372286,12471024,12477932,12538861,12661006,12885772,14570915,14574404,15144186,15317815,15358775,15489334,15546864,15951434,16012170,16189514,16192284,16263117,16316992,16344560,16646955,16882988,17158866,17207965,18029348,18468998,18754678,19027007,19071123,19860857,20130090,20195357,21105033,21516116,21543871,21988832,22658674,22863883,22939629,23266556,23545662,23818989,23966943,24154728,24210758,24613305,24722188,24999209,25231053,25416956,25609649,25614626,25876703,25900982,26179146,26186194,26496610,26638075	15		NP_001017408.1|MSAGGPCPAAAGGGPGGASCSVGAPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQSVSQINHKLEAQLVDLKSELTETQAEKVVLEKEVHDQLLQLHSIQLQLHAKTGQSADSGTIKAKLERELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNPGASCKDTSGEIKVLQGFNKKAVTDTHENGDLGTASETPLDDGASKLDDLHTLYHKKSY,NP_065132.1|MSAGGPCPAAAGGGPGGASCSVGAPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQSVSQINHKLEAQLVDLKSELTETQAEKVVLEKEVHDQLLQLHSIQLQLHAKTGQSADSGTIKAKLSGPSVEELERELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNPGASCKDTSGEIKVLQGFNKKAVTDTHENGDLGTASETPLDDGASKLDDLHTLYHKKSY
48	Gopc	94221	Golgi-associated PDZ and coiled-coil motif-containing protein	Gopc	2210402P09Rik|AI844555|CAL|FIG|GOPC1|PIST	mouse	NM_001199272.1,NM_053187.3	NP_001186201.1,NP_444417.2	AC_000032.1,NC_000076.6,NT_039492.8,NW_001030413.1	Q8BH60	Cytoplasm.  Golgi apparatus membrane.	NULL			Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes. {ECO:0000269|PubMed:12149515, ECO:0000269|PubMed:12372286, ECO:0000269|PubMed:15317815}.	Mm.390258	8889548,10349636,11042159,11076861,11162552,11217851,11384996,11520064,12149515,12372286,12466851,12471024,12477932,12885772,14610273,15136571,15317815,15329396,15489334,15700542,15700543,15893389,16141072,16141073,16602821,16765935,17360959,18287559,18288386,18468998,20958966,21677750,22949614,24523912	19		NP_001186201.1|MSAGGPCPAGAGGGPGGSSCPVGVSPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLRSELTETQAEKVVLEKEVHEQLLQLHSTQLQLHAKTGQSVDSGAIKAKLSVHSVEDLERELEANKTEKVKEARLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGSGNSGASCKDSSGEMKMLQGYNKKAVRDAHENGDVGAAGESPLDDTAARAAHLHSLHQKKAY,NP_444417.2|MSAGGPCPAGAGGGPGGSSCPVGVSPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLRSELTETQAEKVVLEKEVHEQLLQLHSTQLQLHAKTGQSVDSGAIKAKLERELEANKTEKVKEARLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGSGNSGASCKDSSGEMKMLQGYNKKAVRDAHENGDVGAAGESPLDDTAARAAHLHSLHQKKAY
50	RAB5A	5868		RAB5A	RAB5	human	NM_001292048.1,NM_004162.4	NP_001278977.1,NP_004153.2	NC_000003.12,NC_018914.2,NT_022517.19,NW_004929309.1	A0A024R2K1,P20339	Cell membrane.	NULL				Hs.475663	1516130,1999336,2493636,2501306,7957092,7991565,8294464,8521472,8831575,9045618,9524117,9697774,9730828,10329441,10491193,10512627,10720461,10722846,10818110,11062261,11076863,11099046,11493665,11536198,11682489,11703925,11718716,11733506,11788822,11792815,11870209,11884531,12034881,12147258,12359748,12432064,12433916,12477932,12612085,12668728,12761223,12832475,12972505,14600265,14613930,14617813,14644159,14669515,14978216,15014045,15016378,15023538,15078902,15207266,15328530,15377662,15378032,15388334,15489334,15489336,15782196,16034420,16141272,16354686,16381901,16525121,16554017,16622416,16754960,16890161,16902405,16923123,17081065,17173037,17301141,17301152,17353931,17403676,17473071,17524504,17562788,17581628,17611268,18005733,18498773,18725540,18755741,18767904,18957427,18974049,18982021,19032933,19118546,19126785,19322201,19372461,19398555,19460345,19620308,19656886,19723633,19759177,19819222,19830447,19913121,19923319,19966785,20376209,20395296,20412119,20457610,20458337,20472552,20534488,20558162,20628086,20847427,20926780,21104291,21203429,21266579,21300063,21378754,21423773,21500550,21640764,21655223,21669283,21835792,21849022,21895870,21987812,21988832,22178872,22341461,22547071,22558309,22768177,22833562,22939629,22942286,22952906,23048039,23086000,23182941,23291133,23382462,23393387,23434372,23454239,23536683,23606746,23687301,23733193,23813952,23815289,23824909,23940042,24102721,24334765,24440914,24466349,24576301,24587345,24659799,24727246,24788845,24848261,24872409,24891604,24980434,25049275,25152371,25179218,25281560,25483964,25496667,25566515,25711083,25737280,25763873,25869668,25900982,25915798,26112597,26168723,26186194,26195760,26344197,26355680,26496610	15		NP_001278977.1|MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCSN,NP_004153.2|MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCSN
51	MYD88	4615		MYD88	MYD88D	human	NM_001172566.1,NM_001172567.1,NM_001172568.1,NM_001172569.1,NM_002468.4,XM_005265172.1,XM_006713170.1	NP_001166037.1,NP_001166038.1,NP_001166039.1,NP_001166040.1,NP_002459.2,XP_005265229.1,XP_006713233.1	NC_000003.12,NC_018914.2,NG_016964.1,NT_022517.19,NW_004929309.1	A0A0A0MS70,A0A0A0MSI9,A0A0A0MST0,Q99836	Cytoplasm.	NULL				Hs.82116	8957090,9013863,9344657,9374458,9575168,9716450,9915784,10383454,10854325,10880445,10952994,11416133,11544529,11743586,11828002,11854210,11880380,11909531,11960013,11976320,12391239,12477932,12531807,12538665,12609980,12646618,12659850,12724322,12761501,12860405,12865424,12885415,14573621,14625308,14630816,14702039,15004556,15107846,15276183,15294994,15342556,15361868,15489334,15623538,15665823,15728506,15760459,15845500,15849357,16024789,16189514,16203735,16236719,16286016,16293622,16365431,16424162,16461741,16482509,16484229,16517734,16517750,16644730,16951688,16961462,16997282,17258210,17276401,17363736,17507369,17507480,17513785,17548806,17567694,17583698,17905570,17920759,17935950,17940625,18070982,18086890,18195069,18221795,18292575,18325643,18458086,18503546,18523439,18539711,18541719,18571728,18581201,18669862,18703508,18719610,18768833,18771998,18776126,18782768,18802114,18810425,18987746,19006693,19120481,19124728,19167362,19254290,19257978,19265123,19281832,19297619,19336475,19423540,19453261,19488045,19494325,19506249,19509286,19543401,19548630,19592493,19593445,19619129,19656901,19745833,19753301,19779605,19786094,19826413,19913121,19917706,19940113,19948740,19950169,20048342,20145198,20145615,20167866,20197549,20219467,20306472,20331378,20406964,20410269,20433840,20438785,20448286,20463618,20485341,20588308,20628086,20639876,20676093,20681284,20802145,20805788,20817868,20824098,20837465,20880684,20937539,20941850,20957750,20966070,21048031,21113489,21179087,21248248,21257927,21273385,21325272,21334391,21383499,21516116,21525878,21536801,21606507,21621419,21640812,21646294,21654189,21792053,21804016,21809339,21897371,21903422,21911421,21949112,21956671,21988832,21991928,22011580,22020631,22043923,22095710,22158417,22219328,22221660,22250084,22288587,22295065,22332739,22474023,22495176,22533866,22541070,22565171,22581261,22640364,22673208,22685567,22739766,22808296,22837180,22848400,22896623,22904187,22931316,22944768,22964479,22985132,22992740,23002119,23013250,23036196,23136947,23186691,23221546,23235763,23255009,23269203,23321251,23355535,23380077,23381138,23419703,23446312,23453969,23460645,23497717,23532735,23549880,23633945,23666053,23712403,23713977,23728346,23776175,23786414,23802631,23836557,23941760,23955458,23962979,23976989,23986494,24019529,24067789,24072850,24113472,24142728,24143223,24153350,24189845,24204290,24224040,24253023,24265315,24285099,24316379,24363429,24366360,24444466,24509637,24553177,24573383,24603331,24622324,24670424,24735611,24782504,24828863,24859878,24887488,24895570,24903481,24977712,24995344,25054155,25055137,25058342,25159121,25160558,25175786,25197661,25216226,25247317,25295729,25299052,25320238,25320320,25344726,25347427,25359991,25360699,25371371,25375272,25389708,25416956,25446563,25475726,25501023,25621893,25691060,25722298,25723115,25766528,25768255,25816840,25819228,25870959,25877355,25886387,25900979,25969543,26186194,26230596,26244327,26294719,26363072,26466961,26468534	15		NP_001166037.1|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIGAAGWWWLSLMITCRARNVTSRPNLHSASLQVPIRSD,NP_001166038.1|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRLARRPRGGCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP,NP_001166039.1|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP,NP_001166040.1|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGAAGWWWLSLMITCRARNVTSRPNLHSASLQVPIRSD,NP_002459.2|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP,XP_005265229.1|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASAAGWWWLSLMITCRARNVTSRPNLHSASLQVPIRSD,XP_006713233.1|MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASAAGWWWLSLMITCRARNVTSRPNLHSASLQVPIRSD
52	RUBCN	9711		RUBCN	KIAA0226|RUBICON|SCAR15	human	NM_001145642.3,NM_014687.2,XM_005269374.2,XM_006713827.2,XM_006713828.2,XM_006713829.2,XM_006713830.2,XM_006713831.2	NP_001139114.1,NP_055502.1,XP_005269431.1,XP_006713890.1,XP_006713891.1,XP_006713892.1,XP_006713893.1,XP_006713894.1	NC_000003.12,NC_018914.2,NG_034153.1,NT_005612.17,NW_004929312.1	Q8N4U6,Q92622	Late endosome. Lysosome.  Early endosome.	NULL				Hs.478868	9039502,11181995,12477932,15146197,15231748,16344560,16641997,19270693,19270696,19550146,19608861,20379614,20562859,20826435,20943950,20974968,21062745,21118109,21241894,22423966,22423967,22493499,22527681,23728897,23954414,24034250,24980960,25594178,25807108,25891078,26496610	15		NP_001139114.1|MQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPGGPRNITIIVEDPIAESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,NP_055502.1|MRPEGAGMELGGGEERLPEESRREHWQLLGNLKTTVEGLVSTNSPNVWSKYGGLERLCRDMQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,XP_005269431.1|MRPEGAGMELGGGEERLPEESRREHWQLLGNLKTTVEGLVSTNSPNVWSKYGGLERLCRDMQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPGGPRNITIIVEDPIAESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,XP_006713890.1|MRPEGAGMELGGGEERLPEESRREHWQLLGNLKTTVEGLVSTNSPNVWSKYGGLERLCRDMQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPGGPRNITIIVEDPIAESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDGSEGSNLTHISKNGLSVSLASMFSDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,XP_006713891.1|MRPEGAGMELGGGEERLPEESRREHWQLLGNLKTTVEGLVSTNSPNVWSKYGGLERLCRDMQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDGSEGSNLTHISKNGLSVSLASMFSDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,XP_006713892.1|MQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPGGPRNITIIVEDPIAESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDGSEGSNLTHISKNGLSVSLASMFSDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,XP_006713893.1|MLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPGGPRNITIIVEDPIAESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDGSEGSNLTHISKNGLSVSLASMFSDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT,XP_006713894.1|MLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAPGGPRNITIIVEDPIAESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDGSEGSNLTHISKNGLSVSLASMFSDADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT
53	SQSTM1	8878	Sequestosome-1	SQSTM1	A170|FTDALS3|OSIL|PDB3|ZIP3|p60|p62|p62B	human	NM_001142298.1,NM_001142299.1,NM_003900.4,XM_011534683.1,XM_011534684.1	NP_001135770.1,NP_001135771.1,NP_003891.1,XP_011532985.1,XP_011532986.1	NC_000005.10,NC_018916.2,NG_011342.1,NT_023133.14,NW_004929325.1	Q13501	Cytoplasm.  Late endosome.  Lysosome. Cytoplasmic vesicle, autophagosome.  Nucleus.  Endoplasmicreticulum.  Cytoplasm, P-body.	NULL			Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin- 1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. {ECO:0000250, ECO:0000269|PubMed:10356400, ECO:0000269|PubMed:10747026, ECO:0000269|PubMed:11244088, ECO:0000269|PubMed:12471037, ECO:0000269|PubMed:15340068, ECO:0000269|PubMed:15802564, ECO:0000269|PubMed:15911346, ECO:0000269|PubMed:15953362, ECO:0000269|PubMed:16079148, ECO:0000269|PubMed:16286508, ECO:0000269|PubMed:19931284, ECO:0000269|PubMed:20168092, ECO:0000269|PubMed:24128730}.	Hs.587290,Hs.724025	8551575,8618896,8650207,8702753,8910285,9184228,9252186,9564850,9566925,9762895,10022904,10356400,10362795,10397530,10708586,10747026,10776788,11244088,11447312,11473345,11563677,11755531,11786419,11852044,11981755,11992264,12034707,12242277,12374763,12431995,12471037,12477932,12700667,12727313,12787561,12813044,12857745,12857950,12869526,12887891,14584883,14676191,14692700,14702039,14702098,15125799,15143057,15146436,15158159,15164150,15176995,15207768,15340068,15489334,15493999,15592455,15647816,15721744,15761153,15802564,15840729,15870274,15911346,15953362,16011831,16079148,16083285,16129434,16159877,16169070,16189514,16252010,16286508,16344560,16405664,16565220,16574459,16630834,16691492,16751776,16793543,16820172,16861740,16874300,16964243,16997282,17052185,17065558,17081983,17120186,17187080,17229007,17237936,17314511,17353931,17550899,17580304,17685470,17898222,17931355,17932931,18083104,18083707,18157088,18174161,18296712,18379439,18379713,18442140,18457658,18543015,18584184,18624398,18653543,18776740,18984666,18992722,19004011,19010391,19013454,19016598,19020788,19021777,19049332,19056867,19067022,19071211,19074260,19197142,19201866,19229298,19250911,19257822,19282458,19285159,19398892,19427028,19427866,19481605,19557423,19589897,19615732,19640926,19780870,19812211,19816510,19822672,19843958,19850933,19903815,19931284,20010802,20018885,20061786,20061800,20098416,20103647,20168092,20173742,20200946,20204693,20230821,20357094,20360068,20378532,20379614,20417604,20421418,20452972,20457763,20495340,20499339,20551902,20562859,20573959,20600853,20604804,20639871,20706999,20711182,20808283,20814791,20837465,20890124,20971078,20974803,20979579,21045561,21062285,21073987,21079414,21118398,21149568,21160040,21173155,21187718,21195346,21220506,21325881,21371883,21412052,21460636,21482715,21516116,21517082,21536669,21544590,21555518,21606687,21617041,21628417,21628531,21646350,21691068,21726808,21735147,21771882,21876553,21900206,21903097,21923101,21931693,21935636,21949121,21959292,21981924,21988832,22017874,22020285,22084127,22098537,22178386,22190034,22190037,22286270,22296116,22320446,22322858,22411133,22421968,22434781,22491873,22525272,22565157,22658674,22674379,22714671,22728060,22792322,22797925,22841931,22863883,22939629,22941224,22952826,22963397,22972638,22992334,23017601,23023376,23117207,23239879,23242280,23266528,23274085,23300799,23303844,23314748,23333919,23345396,23398456,23402259,23417734,23434281,23437331,23455922,23459205,23503661,23564079,23637164,23640897,23649778,23658060,23681079,23686137,23752596,23787295,23795962,23824909,23911927,23942205,23989536,24011591,24023838,24042580,24065390,24086340,24086678,24089205,24100292,24121507,24122957,24128730,24138988,24162737,24189400,24220190,24240628,24270048,24270664,24322982,24332042,24366813,24394643,24413169,24416372,24440703,24486447,24553345,24582747,24599075,24613305,24616100,24618016,24619419,24642144,24664425,24667411,24668264,24690104,24711643,24769734,24778252,24806912,24879152,24886973,24899140,24927592,24928389,24971696,24983366,24991827,24998849,25002027,25002530,25007327,25013806,25015291,25026213,25034783,25040165,25042851,25050557,25088198,25101860,25103771,25114083,25126726,25127057,25144556,25157103,25158237,25241215,25269472,25277244,25281560,25311206,25338734,25339774,25416956,25429107,25433461,25450619,25466963,25483962,25505069,25516445,25526666,25653352,25670202,25686248,25693804,25708205,25723488,25796131,25832774,25841304,25847297,25852190,25921531,25937318,25939382,25969509,25972374,25973309,25984893,25996949,26008206,26018155,26043024,26075355,26109433,26150155,26186194,26187466,26268733,26279575,26347139,26349538,26363065,26364802,26389662,26412716,26413874,26417105,26427388,26496610,26546463,26637326,26638075,26673895,26722036,26746706	15		NP_001135770.1|MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL,NP_001135771.1|MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL,NP_003891.1|MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL,XP_011532985.1|MARGTGAGAQGSEGGGGGGRGPGPGSGRGGGPGAGRGPGQGARRPPLRAQALCPVLREEEQAQKGRGRYQAHCRYQGRGTLAASPPRQGRAGPGWAGLGGESRGPAWIWGLDLGPPRSRRRRAGRPGFKGAAAPPSPAPRGGGVGAGGRDPDRLPQPRVGSCESASVSARLISHGRCTRTWLLAELRRKSYNSLACNMGLEKGFSAASGGRLDCRRRPGRVYFHLRRRWHLQAASGRFGPHHR,XP_011532986.1|MARGTGAGAQGSEGGGGGGRGPGPGSGRGGGPGAGRGPGQGARRPPLRAQALCPVLREEEQAQKGRGRYQAHCRYQGRGTLAASPPRQGRAGPGWAGLGGESRGPAWIWGLDLGPPRSRRRRAGRPGFKGAAAPPSPAPRGGGVGAGGRDPDRLPQPRVGSCESASVSARLISHGRCTRTWLLAELRRKSYNSLACNMGLEKGPQMLNLRGQRKSFSSLT
54	NBR1	4077		NBR1	1A1-3B|IAI3B|M17S2|MIG19	human	NM_001291571.1,NM_001291572.1,NM_005899.4,NM_031858.2,NM_031862.3,XM_006721903.1,XM_011524813.1	NP_001278500.1,NP_001278501.1,NP_005890.2,NP_114068.1,XP_006721966.1,XP_011523115.1	NC_000017.11,NC_018928.2,NG_005905.2,NT_010783.16,NW_004929407.1	A0A024R1V3,B7Z5R6,Q14596	Cytoplasm. Cytoplasmic vesicle, autophagosome. Lysosome.  Cytoplasm, myofibril,sarcomere, M line.	NULL				Hs.277721,Hs.708158	7545954,7581362,7584044,7997258,8069304,8700509,11179671,11856312,12107412,12477932,12813044,14702039,15489334,15802564,15840729,16189514,16713569,16861740,19250911,19398892,19427866,19822672,19946888,20010802,20368287,20379614,20417604,20562859,20808283,21121670,21296869,21606687,21620860,21909099,21935636,21989022,22430266,22484440,22558309,22728060,23239026,23376485,23649778,24128730,24269898,24413169,24664425,24667779,24692539,24769734,24879152,25007327,25042851,25043814,25416956,25609649,26112016,26186194,26496610,26638075	15		NP_001278500.1|MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQGLWGLLSFLHLAKKCFFLKAPSEAFSWF,NP_001278501.1|MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGANNF,NP_005890.2|MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY,NP_114068.1|MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY,XP_006721966.1|MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY,XP_011523115.1|MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKALFAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNNDWYSQRY
56	VMP1	81671	Vacuole membrane protein 1	VMP1	EPG3|TANGO5|TMEM49	human	NM_030938.3	NP_112200.2	NC_000017.11,NC_018928.2,NT_010783.16,NW_004929407.1	Q96GC9	NULL	NULL			Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions. {ECO:0000250, ECO:0000269|PubMed:17724469}.	Hs.444569,Hs.708260	11076863,11230166,11256614,11785947,12477932,15466293,15489336,16381901,17724469,17940279,18384814,18550798,19019082,19056683,19322201,19490893,20299819,21173155,21467264,22144109,22333543,22404213,22535956,22971212,23118302,23316280,23460482,23710913,24365149,26186194,26638075	15	1->45,211->240,330->366,390->406	NP_112200.2|MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLEILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK
57	TP53INP2	58476	Tumor protein p53-inducible nuclear protein 2	TP53INP2	C20orf110|DOR|PINH|dJ1181N3.1	human	NM_021202.1,XM_005260476.2,XM_006723841.2,XM_011528952.1,XM_011528953.1	NP_067025.1,XP_005260533.1,XP_006723904.1,XP_011527254.1,XP_011527255.1	NC_000020.11,NC_018931.2,NT_011362.11,NW_004929418.1	Q8IXH6	Cytoplasm, cytosol.  Nucleus.  Nucleus, PMLbody.  Cytoplasmic vesicle, autophagosome.	NULL			Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. {ECO:0000269|PubMed:18030323, ECO:0000269|PubMed:19056683, ECO:0000269|PubMed:22470510}.	Hs.516994	11780052,12477932,15489334,17238154,19056683,19934309,20010805,21467300,22470510,22750142,23728790	15		NP_067025.1|MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY,XP_005260533.1|MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY,XP_006723904.1|MDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY,XP_011527254.1|MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY,XP_011527255.1|MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY
58	BNIP3	664	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3	BNIP3	NIP3	human	NM_004052.3	NP_004043.3	NC_000010.11,NC_018921.2,NT_030059.14,NW_004929377.1	Q12983,Q6NVY4	NULL	NULL			Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway. {ECO:0000269|PubMed:19935772, ECO:0000269|PubMed:22292033}.	Hs.144873	7478990,7954800,8125298,9396766,9575197,9867803,9973195,10381623,10625696,10891486,10922063,12215374,12226479,12477932,12690108,12879018,15164054,15289340,15328198,15489334,15560738,15709167,15856026,15868100,16002567,16169070,16189514,16217754,16219518,16357180,16765911,16799636,16803523,17207965,17255267,17360363,17394490,17576382,17576813,17600828,17638546,17638890,17729412,17786027,17928295,18029348,18059169,18092960,18163427,18309324,18359286,18371312,18476629,18551130,18728663,18838203,19060904,19088195,19273585,19339613,19505343,19535684,19593445,19641497,19668230,19690192,19799812,19935772,19956881,20026130,20082478,20100468,20201926,20368736,20436456,20437871,20637734,20801175,20855536,20963496,20973794,20978322,21037586,21152877,21210091,21293853,21318419,21409489,21516116,21573703,21711117,21792176,21911457,21987236,21988832,22173550,22292033,22302006,22455137,22458929,22505714,22639046,23142642,23160801,23209295,23216071,23291726,23364257,23504944,23538299,23579274,23667095,23688833,23728617,23851496,23979608,24162774,24211581,24402046,24824755,24928088,25416956,25436615,25547946,25618603,25891311,26012884,26102349,26186194,26253153,26416963	15		NP_004043.3|MGDAAADPPGPALPCEFLRPGCGAPLSPGAQLGRGAPTSAFPPPAAEAHPAARRGLRSPQLPSGAMSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF
61	VAC8	856702	Vacuolar protein 8		YEB3	baker's yeast	NM_001178828.3	NP_010903.3	NC_001137.3	P39968	Vacuole membrane.	NULL			Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. {ECO:0000269|PubMed:9490720}.		8849441,8885233,9169868,9490720,9664035,9739084,10837477,10888680,11078525,11283351,11406591,11441010,11805837,12529432,12594460,14519092,14685280,14690608,14764870,15520806,15701652,15901835,16186255,16269340,16301533,16554755,16720644,16824055,16854988,16978392,17565946,17923092,17925448,18467557,18541004,18627629,18676811,18690010,18701704,18757749,19223769,19416974,19453970,20041197,20526336,21196517,21196523,21987634,22140548,22199229,22384331,22447937,22885598,22940862,23209445,23222640,23270647,23547030,24374311,25987606,26061644	28		NP_010903.3|MGSCCSCLKDSSDEASVSPIADNEREAVTLLLGYLEDKDQLDFYSGGPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQVSREVLEPILILLQSQDPQIQVAACAALGNLAVNNENKLLIVEMGGLEPLINQMMGDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSKHIRVQRNATGALLNMTHSEENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLAQTEPRLVSKLVSLMDSPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRLLDYKDSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDSPVSVQSEISACFAILALADVSKLDLLEANILDALIPMTFSQNQEVSGNAAAALANLCSRVNNYTKIIEAWDRPNEGIRGFLIRFLKSDYATFEHIALWTILQLLESHNDKVEDLVKNDDDIINGVRKMADVTFERLQRSGIDVKNPGSNNNPSSNDNNSNNNDTGSEHQPVEDASLELYNITQQILQFLH
65	YPK1	853733	Serine/threonine-protein kinase YPK1		SLI2	baker's yeast	NM_001179692.1	NP_012796.1	NC_001143.9	P12688	Cytoplasm.  Cellmembrane.	NULL		60673,9821	Plays an essential role in the proliferation of yeast cells. Involved in a signaling pathway, required for optimal cell wall integrity, that acts in parallel with the PKC1-SLT2-dependent pathway. Downstream kinase in the sphingolipid-mediated signaling pathway. Its phosphorylation is regulated by the intracellular sphingolipid concentration. Cooperates with SLI1 in mediating resistance to the sphingolipid biosynthesis inhibitor drug myriocin (ISP-1). Its kinase activity is essential for the resistance. Required for both receptor-mediated and fluid-phase endocytosis, but is not necessary for receptor phosphorylation or ubiquitination. Necessary for the internalization of plasma membrane proteins carrying different types of internalization signals. Acts downstream of the PKH kinases to control endocytosis by phosphorylating components of the endocytic machinery. Phosphorylation of residue Thr-504 in the activation loop is essential for activity. phosphorylates and down-regulates flippase activator FPK1. {ECO:0000269|PubMed:10825204, ECO:0000269|PubMed:12221112, ECO:0000269|PubMed:15470109, ECO:0000269|PubMed:19966303, ECO:0000269|PubMed:8437590}.		8196765,8437590,8849441,10074427,10825204,11839800,12196392,12221112,14593073,14764870,15025559,15470109,15715908,15766533,15840588,16554755,17507646,17923092,18194531,18245329,18296441,18467557,19269370,19835169,19966303,20170199,20489023,20516150,21127252,21460040,22080611,22189709,22199229,22282571,22307609,22579291,22988299,23332755,23712011,24462291,24465216,25002487,25228766,25253719,25258318,25279700,25378585,26274562,26582391,26634277,26673895	28		NP_012796.1|MYSWKSKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHDASITRSSLDRKGTINPSNSSVVPVRVSYDASSSTSTVRDSNGGNSENTNSSQNLDETANIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPITSSEQILNKLLASGVPPPHKEISKEVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDNTVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQDEKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR
69	ATG33	851070	Autophagy-related protein 33			baker's yeast	NM_001182245.1	NP_013460.1	NC_001144.5	Q06485	Mitochondrion membrane.	NULL			Involved in the selective degradation of mitochondria via autophagy during starvation and at post-log phase. {ECO:0000269|PubMed:19793921, ECO:0000269|PubMed:20364111}.		8849441,9169871,12192589,14562095,15817685,16554755,19793921,19840948,20093466,23332755,24586198,24769239	28		NP_013460.1|MSVCLAITKGIAVSSIGLYSGLLASASLITSTTPLEVLTGSLTPTLTTLKNAATALGAFASTFFCVSFFGAPPSLRHPYLLYGMLVAPLSSFVLGCASNYQSRKYSKVSKESSLFPEDSKLAASELSDSIIDLGEDNHASENTPRDGKPAATTVSKPAEALHTGPPIHTKNLIAATAIAIVGFVQAVIGVYGEGQFI
70	ATG34	854071	Autophagy-related protein 34			baker's yeast	NM_001183337.1	NP_014558.1	NC_001147.6	Q12292	Preautophagosomal structure membrane.	NULL			Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole. {ECO:0000269|PubMed:20639194, ECO:0000269|PubMed:20659891}.		8849441,9169874,10688190,18087042,18719252,19840948,20489023,20639194,20659891,23332755,24705553,25281559	28	1->22,66->74,139->290,349->412	NP_014558.1|MKIAVETTLFDFFVIDQFKKSTFSAPNTKVDTIKGCINKFIEQFNVYDEQHIFWQPPGKSNVRLLSNANDFGQLGNFLHKKIKCNIFIGEEALRKYDLNICGPYDKFVENSDPSVKKVVNRDDVMLSRKCLNIISEQLSILEKSISKAQNQVLQSSEVEGKKCIILPEDKPELIKFFSKFETSVQLQEVYEGYKVYEKLLQKFGGQKKRMESFLNENTPMSGAEAIKQINISEELKEKGERLTTPNDPLLHVEVSNEDNSLHFILYNKTNIIIPGNCTFEFSSQISEVFSIKMGPHEIGIKGQKELWFFPSLPTPLSNYTMKVVNQDGETILVGKCADSNEITLKSPLASFSTGSFQTGSFHTLQDPTNVFRADALSSPDESSIMSTPFLGETDEVYNSGSTLSRPFTWEEI
73	APE1	853758	Vacuolar aminopeptidase 1 {ECO:0000303|PubMed:17329814}		API|LAP4|YSC1	baker's yeast	NM_001179669.1	NP_012819.1	NC_001143.9	P14904	Vacuole.	NULL			Resident vacuolar enzyme that catalyzes the removal of amino acids from the N-terminus of peptides and proteins. Also acts as the major cargo protein of the cytoplasm-to-vacuole targeting (Cvt) pathway. The precursor form of aminopeptidase 1 (prApe1) assembles into dodecamers and the propeptide mediates the aggregation of dodecamers into higher multimers. The multimers are then recognized via the propeptide by their receptor ATG19, and ATG19 further interacts with ATG11, which tethers the APE1-ATG19 complex to the pre-autophagosomal structure (PAS). The cargo- receptor complex (also Cvt complex) is selectively enwrapped by a double-membrane structure termed the Cvt vesicle under vegetative growth conditions and by a similar but larger double-membrane structure termed the autophagosome under nitrogen starvation conditions. The Cvt vesicle or the autophagosome fuses with the vacuolar membrane and release its content in the vacuolar lumen. In the vacuole, prApe1 is processed into mature aminopeptidase 1 (mApe1). {ECO:0000269|PubMed:11382752, ECO:0000269|PubMed:11430817, ECO:0000269|PubMed:15138258, ECO:0000269|PubMed:22123825, ECO:0000269|PubMed:363165, ECO:0000269|PubMed:8901576, ECO:0000269|PubMed:9214379, ECO:0000269|PubMed:9412464}.		1400574,2651436,2689224,3882418,8196765,8849441,10688190,11283351,11430817,11805837,12479808,17329814,18716881,18719252,19343713,19398890,19536198,19840948,20065090,20093466,20170199,20489023,20639194,20659891,21228276,21343297,22123825,22515269,22826123,22842922,23222640,23332755,23801757,24470217,24705553,25287303,26208681,26673895,26849847	28		NP_012819.1|MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
75	ARP2	851532	Actin-related protein 2		ACT2	baker's yeast	NM_001180088.1	NP_010255.1	NC_001136.10	P32381	Cytoplasm, cytoskeleton, actin patch.	NULL		8678,81037,9711,22863,29982,30849,8237,7405	Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). {ECO:0000250}.		8698808,8849441,9169867,9210376,9218799,9243513,10322115,10377407,10512884,10648569,11248049,11331312,11433303,11533442,11743205,11805826,11805837,12242276,12429847,12499356,12808026,14764870,15149595,15371547,15485833,15592479,15657399,15687504,15711538,15715908,15857833,16107558,16155567,16183906,16262445,16382152,16429126,16554755,16606443,16862144,17118118,17210948,17978096,18287533,18381280,18467557,18511909,18719252,18757749,18762987,19272406,19440046,19840948,19962315,20071330,20093466,20147449,20170199,20207164,20508643,21035341,21232131,21321079,21454476,21552543,21734642,22199229,22271760,22615397,22761830,23148219,23200048,23292935,23332755,23390603,23583819,23727094,23801757,23868593,23891562,24133141,25026036,25228766	28		NP_010255.1|MDPHNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEERASVATPLKDIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTSNGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEKLCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPGVGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPSRLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR
76	ARP3	853528	Actin-related protein 3		ACT4	baker's yeast	NM_001181723.3	NP_012599.3	NC_001142.9	P47117	Cytoplasm, cytoskeleton, actin patch.	NULL			Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). {ECO:0000250}.		8641269,8849441,9210376,10322115,10377407,10512884,11248049,11331312,11433303,11533442,11805826,11805837,12429847,12499356,14554195,15485833,15592479,15657399,15857833,16183906,16262445,16382152,16429126,16554755,16622836,16862144,17200106,18004728,18381280,18757749,19272406,19536198,19840948,19962315,20071330,20170199,20207164,20362448,21035341,21454476,21552543,21966278,23148219,23200048,23222640,23292935,23332755,23390603,23727094,23868593,23891562,24133141,24855027,25026036	28		NP_012599.3|MSYLNNPAVVMDNGTGLTKLGFAGNDSPSWVFPTAIATAAPSNTKKSSGVGAPSAVSNEASYFGNSTSATNFNGATGGLLSNNLSGKRGTEDLDFYIGNEALVASQGPSYSLSYPIRHGQVENWDHMERFWENSIFKYLRTEPEDHFFLLTEPPLNPPENREQVAEIFFESFNCAGLYIAVQAVLALAASWTSSKVTDRSLTGTVIDSGDGVTHVIPVAEGYVIGSAIKNIPIAGRDITLFIQSLLRERGEADTSLRTAEKIKQEYCYVCPDIVKEFNKFDKDPSKFAQFVVENQEKTRRKVVDIGYERFLAPEIFFNPEIASSDFLTPLPTVVDQTIQACPIDVRKGLYNNIVLSGGSTMFKDFGRRLQRDLKSIVNNRIAQSELLSGTKSTGVDVSVISHRKQRNAVWFGGSLLAQTAEFKGYCHTKKDYEEYGPEIVRNFSLFNMV
77	sepa-1	173196				nematode	NM_060938.3	NP_493339.1	NC_003279.8	G5EC37	NULL	NULL				Cel.18438	9851916,19167332,24140420	5		NP_493339.1|MTPLSALTSNPAPSPPPKFALGKCPATAIHVVSVLRPNRQRFCYEKTDAGDLIPHKCLICQPILTEKHISPYYAVYSDLLEDFVLFGYNTMTGKMEQFIYAFKTDCFVEVNRPEIKYNPAFLVKGNVVVALNGPEGELVVIERDCRGLLSKESTSYGQFRTLPTAALRTLTLQDLERDRWDRAANSDEVKISSGNESFDRLYAEYQKNLPRFQVRQCLHLNKEFLCVYSKTSGDYTRLEYIDETGDFQKISCTLCTCEVTESNLIPLYVERNASELVIHVHNTENNQIEQYIYDVRTFGFVQVKRNLVYDPKKITSGLNLFMAENIDNRKVYMIMRGRDGRLQKETSGSGGFEKMQPVAVKTFQVQWVEMKTEFEKKKASTERVEPQHPVQTEGEDIMETVLAMVESFNCDLRKELGLTQDQEIPRKAPRVESAETEENIVKNLEKLQIAKDPEEPTTAASEGGNTYGYQELDDTMSEGLLEKEAESKHQDANEPEPVKNVTYEPDVAAMDKKKKRRELKSRLNKINAQIDELEKRRMERAGKKQVVSSSVPSEEAAQVEAPASPALAENTNQISNEETPKIDIFEGYNGSFLFGTNTSKEWIVEDIRNHMVGKLLKAFWPRIQNVEEMNGELFKKLIANARKCETEILEASNDRDEYYRLMQLTVDQILKKTLKKDQRATEHNHQQPTQSSDELAKNHEKN
78	DIRAS3	9077	GTP-binding protein Di-Ras3	DIRAS3	ARHI|NOEY2	human	NM_004675.3,XM_006711027.2	NP_004666.1,XP_006711090.2	NC_000001.11,NC_018912.2,NG_011753.1,NT_032977.10,NW_004929290.1	O95661	Cell membrane.	NULL				Hs.194695	9874798,11418188,12477932,12485503,12771940,12874023,14506155,14702039,15489334,16061651,16158053,16710414,18286529,18302158,18612997,19033662,19435463,19482475,19639215,19759414,21093415,21244707,21602127,21643014,21933150,22117988,22427032,22497484,22605333,23157514,23247805,23447002,23604529,23678541,23801152,23871723,24104479,24458808,24476894,24676336,24769729,24879154,25077680,25193278,25499977,25640309,25675421,26186194,26247722	15		NP_004666.1|MGNASFGSKEQKLLKRLRLLPALLILRAFKPHRKIRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSDDTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCIIM,XP_006711090.2|MSCLFSIICGKDYLSCIKLLLDFRLKSVGPVFVGKVLPEAYSNRCQADLAPLCVGPAPHSWFLTTYCASGIYACYPHSLRPRTPLLCASRNIKPRRSELLGCPVGCRGSLSEQRICLLGCLVRASEKGVSCCQLSVGELVHVSPLRIPTMGNASFGSKEQKLLKRLRLLPALLILRAFKPHRKIRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSDDTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCIIM
79	RHEB	6009		RHEB	RHEB2	human	NM_005614.3,XM_011516457.1	NP_005605.1,XP_011514759.1	NC_000007.14,NC_018918.2,NT_007933.16,NW_004929333.1	A0A090N900,Q15382	Endomembrane system.	NULL				Hs.283521,Hs.568850,Hs.647068	8206940,8543055,8661031,8889548,9001246,9099708,9130713,9847074,10924367,11980706,12477932,12690205,12771962,12820960,12842888,12853948,12869548,12869586,12906785,14702039,15150271,15308774,15340059,15388940,15489334,15728574,15755954,15772076,15775987,15809305,15809346,15854902,15878852,15951850,16006564,16098514,16344560,16631613,16803888,16915281,17018601,17077083,17470430,17928295,17991864,18324915,18521078,18550814,18650380,18658153,18708577,18708578,18842593,18948269,19056867,19222999,19258434,19570981,19636822,19838215,20048149,20053679,20127734,20354165,20368287,20375271,20381137,20388784,20458337,20554106,20685651,20732420,20818424,20837708,21048031,21135540,21163940,21336308,21412983,21437936,21516116,21784859,21988832,23376485,23409921,23559067,23863162,24337580,24368770,24403554,24648513,25422319,25446900,25476905,25799580,26186194,26319900,26344197	15		NP_005605.1|MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSVM,XP_011514759.1|MGTFNLGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSVM
80	TSC1	7248		TSC1	LAM|TSC	human	NM_000368.4,NM_001008567.1,NM_001162426.1,NM_001162427.1,XM_005272211.1,XM_006717271.1,XM_006717272.2,XM_011518979.1	NP_000359.1,NP_001155898.1,NP_001155899.1,XP_005272268.1,XP_006717334.1,XP_006717335.1,XP_011517281.1	NC_000009.12,NC_018920.2,NG_012386.1,NT_008470.20,NW_004929367.1	Q32NF0,Q86WV8,Q92574,X5D9D2	NULL	NULL				Hs.370854	9039502,9242607,9328481,9580671,9803264,9809973,9924605,10227394,10533067,10570911,10585443,10607950,10806479,10807585,10915759,11112665,11175345,11290735,11307618,11444800,11686512,11741832,11741833,11774213,11829138,12015165,12062115,12112044,12147258,12167664,12176984,12226091,12271141,12477932,12511557,12766909,12773159,12773162,12773163,12820960,12853839,12869586,12894220,14551205,14559897,14633685,14651849,14680818,14756965,14985384,15059224,15072102,15314020,15324660,15340059,15342917,15355997,15477556,15589136,15595939,15624760,15647351,15798777,15851026,15851513,15963462,16211238,16258273,16339216,16344560,16424383,16464865,16554133,16636147,16897363,16909113,16940165,16996505,17043358,17077083,17114181,17273797,17287951,17304050,17308101,17353931,17355907,17376623,17378684,17522300,17658474,17693255,17717601,17979178,17997379,18032745,18342602,18368626,18381890,18397877,18411301,18413730,18480009,18538015,18772611,18794342,18794346,18830229,18926585,19005330,19058789,19169254,19175396,19357198,19419980,19422538,19608861,19747374,19918125,19966866,20146692,20166753,20185476,20301399,20368287,20371605,20383465,20412061,20453000,20547222,20562859,20605525,20658316,20819778,20877415,21048031,21134130,21243421,21309039,21329690,21345208,21412983,21449900,21559457,21709159,21712385,21784859,22025691,22161988,22490766,22608477,22658674,22795129,22903760,22923433,23169238,23254740,23275563,23389244,23401075,23455924,23788249,23793025,23846400,23851502,23857276,23878397,23891004,24073910,24077282,24477276,24529380,24599401,24615476,24633152,24722188,24770722,25209900,25434723,25498131,25565629,25796537,25814554,25889454,25900779,25915427,25927202,26186194,26496610	15		NP_000359.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS,NP_001155898.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS,NP_001155899.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS,XP_005272268.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS,XP_006717334.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS,XP_006717335.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKF,XP_011517281.1|MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS
81	TSC2	7249		TSC2	LAM|PPP1R160|TSC4	human	NM_000548.4,NM_001077183.2,NM_001114382.2,NM_001318827.1,NM_001318829.1,NM_001318831.1,NM_001318832.1,NM_021055.1,NM_021056.1,XM_005255529.3,XM_005255	NP_000539.2,NP_001070651.1,NP_001107854.1,NP_001305756.1,NP_001305758.1,NP_001305760.1,NP_001305761.1,XP_005255586.2,XP_005255588.2,XP_011520938.1,XP_	NC_000016.10,NC_018927.2,NG_005895.1,NT_010393.17,NW_004929400.1	B3KWH7,H3BMQ0,P49815,Q5HYF7,X5D2U8,X5D7Q2	NULL	NULL				Hs.90303	1303246,1870099,7558029,7581393,7608212,7823706,8269512,8634701,8789450,8806680,8824881,8825048,8933518,9045618,9302281,9328481,9361032,9463313,9580671,9809973,9829910,9831664,10052455,10069705,10205261,10206124,10533067,10570911,10585443,10607950,10732801,10735580,10807585,10823953,10915759,11112665,11175345,11290735,11403047,11533041,11686512,11703097,11741832,11741833,11781698,11811958,11836366,12015165,12062115,12127687,12147258,12150915,12167664,12172553,12176984,12271141,12364343,12438239,12468542,12477932,12511557,12547695,12581886,12582162,12711473,12752578,12766909,12771962,12773159,12773162,12773163,12820960,12842888,12869586,12894220,14551205,14559897,14651849,14680818,14690447,14702039,14756965,14871804,14985384,15024740,15039427,15059224,15066998,15072102,15150271,15161933,15175323,15231735,15261145,15314020,15324660,15340059,15342917,15355997,15477556,15489334,15579767,15589136,15595939,15616553,15624760,15647351,15757502,15798777,15851026,15851513,15854902,15874888,15963462,16053916,16192644,16211238,16213898,16237225,16258273,16339216,16341938,16344560,16357142,16388022,16424383,16464865,16537497,16554133,16624901,16636147,16835931,16897363,16905638,16940165,16959574,17018601,17043358,17077083,17081983,17114181,17114346,17163575,17234746,17273797,17287951,17304050,17353931,17373211,17458623,17470459,17592551,17632432,17658474,17671177,17693255,17888633,17922028,17975002,17979178,17989114,18029348,18032745,18060739,18085521,18094073,18298802,18302728,18320306,18342602,18368626,18381890,18411301,18451215,18538015,18624398,18794342,18794346,18807177,18848473,18926585,18958173,18974095,19005330,19058789,19086053,19175396,19250671,19259131,19265534,19332694,19357198,19389623,19395678,19419980,19422538,19443708,19608861,20042714,20145209,20146692,20160076,20166753,20169078,20169165,20201926,20219685,20237422,20301399,20304964,20354165,20363874,20412061,20453000,20530489,20605525,20618440,20622004,20639436,20658316,20671064,20818424,20834067,20882401,21036916,21048031,21134130,21145542,21243421,21252315,21309039,21329690,21332470,21345208,21407201,21412983,21419848,21449900,21533174,21555252,21784859,21795849,21846442,21900206,21900748,21910228,21949787,22001647,22090422,22189265,22251200,22287548,22456611,22490766,22608477,22707510,22795129,22867869,22889411,22903760,22939629,23217510,23251661,23254740,23348097,23389244,23689538,23788249,23818547,23846400,23867796,23878245,23878397,23891004,23947572,24075384,24077282,24163370,24255178,24271014,24318044,24372178,24398473,24444419,24529380,24599401,24606538,24683199,24722188,24748662,24794161,24917535,25114899,25185584,25281918,25355409,25432535,25476905,25498131,25563326,25565629,25654764,25724664,25780943,25921289,25927202,25936802,25972538,26186194,26252095,26496610,26563443	15		NP_000539.2|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,NP_001070651.1|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,NP_001107854.1|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,NP_001305756.1|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,NP_001305758.1|MECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,NP_001305760.1|MICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,NP_001305761.1|MEGFSGASWSTMAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,XP_005255586.2|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,XP_005255588.2|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,XP_011520938.1|MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWAGIASQREAVGCRAPLCLIDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV,XP_|
82	PTEN	5728		PTEN	10q23del|BZS|CWS1|DEC|GLM2|MHAM|MMAC1|PTEN1|TEP1	human	NM_000314.6,NM_001304717.2,NM_001304718.1,XM_006717926.2,XM_011539981.1,XM_011539982.1,XR_945789.1,XR_945790.1,XR_945791.1	NP_000305.3,NP_001291646.2,NP_001291647.1,XP_006717989.1,XP_011538283.1,XP_011538284.1	NC_000010.11,NC_018921.2,NG_007466.2,NT_030059.14,NW_004929376.1	A0A0U1RR63,F6KD01,P60484	Secreted.	NULL				Hs.500466,Hs.729457	7728760,8889548,9072974,9090379,9140396,9187108,9241266,9256433,9259288,9286463,9326929,9331071,9345101,9354427,9354433,9356475,9367992,9393744,9399897,9425889,9439675,9467011,9593664,9600246,9616126,9635567,9697695,9735393,9794233,9797362,9811831,9832031,9915974,9927060,10051160,10092130,10193515,10213484,10234502,10340391,10400703,10400993,10468583,10555148,10582703,10646847,10706759,10748157,10748870,10760291,10807691,10817502,10852473,10866302,10866658,10889927,10918569,10940933,10955808,10978354,11035285,11058880,11121587,11146448,11156385,11179477,11190805,11230179,11259087,11270682,11303600,11476065,11494117,11504770,11689295,11707428,11729185,11748304,11751500,11784722,11799112,11801303,11836379,11849740,11854177,11857088,11866895,11870516,11875759,11896207,11906179,11908870,11916965,11925138,11932928,11943731,11948419,11948491,11953696,11986403,12055674,12067477,12077252,12077256,12084351,12085208,12091320,12115563,12119278,12133897,12168088,12168116,12176037,12177006,12190124,12203362,12203792,12209607,12235113,12297295,12351634,12367630,12370746,12370766,12379854,12414663,12415190,12429629,12452054,12459646,12471211,12477932,12495846,12508347,12509854,12517803,12535639,12543774,12569555,12569572,12569575,12620407,12620973,12632503,12668978,12684422,12687015,12695913,12712134,12717346,12743124,12743604,12767263,12788938,12804776,12808147,12833416,12839924,12844284,12857747,12869565,12917336,12918097,12960424,14516315,14519639,14532122,14534684,14557489,14559824,14561749,14566704,14574156,14623110,14623898,14642363,14663583,14674989,14699494,14702039,14711368,14724591,14737113,14976311,14981940,15009714,15043466,15046604,15046605,15069540,15126336,15129904,15172121,15196854,15205473,15209376,15231710,15240129,15273733,15287024,15355975,15382065,15453811,15457582,15468057,15475931,15476185,15489334,15492994,15500293,15516982,15517593,15523694,15532706,15537704,15543611,15551732,15564381,15569824,15584861,15589575,15623531,15633233,15668893,15674339,15701646,15707982,15710331,15717329,15725467,15725474,15764699,15766664,15784509,15793569,15802268,15803130,15805158,15824172,15843377,15848175,15891996,15897909,15900596,15948123,15951562,15968641,15986432,15987703,15988030,15994292,16012720,16020969,16052674,16055704,16088943,16096376,16107342,16124450,16154532,16169070,16179636,16194892,16219695,16220831,16274701,16325763,16331670,16331889,16371363,16371366,16385451,16418168,16421604,16424003,16425372,16432235,16436456,16456542,16457151,16487009,16496415,16506206,16525657,16534839,16537447,16571650,16574322,16598737,16621980,16637073,16652388,16676006,16676097,16697957,16697958,16702386,16704528,16707597,16739377,16773562,16793127,16807353,16810057,16818626,16821090,16829519,16842970,16845383,16849370,16861931,16872708,16883792,16912159,16916644,16938570,16949921,16951148,16963781,16972255,16984224,17000554,17006756,17013611,17033968,17043057,17060456,17062663,17067457,17097286,17101085,17108713,17126809,17151929,17157319,17178862,17218260,17218261,17218262,17219201,17235455,17236582,17242191,17255257,17274640,17277022,17300726,17328268,17334236,17341483,17345711,17347137,17348444,17357516,17369847,17372210,17390041,17392703,17393112,17405772,17420249,17427195,17438373,17441421,17444818,17452061,17452630,17471559,17479230,17483060,17490733,17504383,17504928,17526801,17563403,17565999,17575221,17581634,17593340,17606718,17611573,17616684,17636424,17638861,17638924,17646270,17657213,17657248,17669465,17672936,17681183,17681738,17684018,17684142,17699782,17700571,17701929,17706140,17711623,17713092,17727244,17729405,17761400,17786367,17826033,17826953,17827710,17845801,17847000,17873065,17873119,17873882,17875968,17880912,17886097,17895757,17908983,17911267,17912443,17919877,17924977,17927875,17927889,17928923,17936563,17939398,17940504,17949781,17954274,17958724,17959258,17974977,17982625,17991315,18006852,18059158,18064632,18065496,18066063,18072631,18082964,18091387,18174230,18178612,18184409,18199536,18199538,18216329,18220422,18226337,18226854,18231751,18239055,18240926,18240930,18260377,18271247,18307411,18316341,18324520,18332865,18335551,18335752,18339852,18339899,18363844,18377423,18383208,18391023,18424911,18425369,18431376,18431742,18456716,18460397,18474617,18482992,18497947,18498243,18500270,18510548,18519768,18544045,18559622,18563337,18579579,18586681,18594467,18599181,18609703,18616639,18620995,18632658,18632660,18652763,18653908,18660489,18662848,18669866,18676680,18676830,18678645,18700047,18702307,18714395,18716620,18720079,18723495,18726116,18728972,18755892,18757403,18757404,18759867,18765664,18769113,18781191,18781614,18787170,18787206,18794875,18794879,18794882,18815879,18826385,18830414,18831514,18844062,18846217,18854827,18928601,18937284,18948956,18950007,18953692,19007975,19010541,19016009,19036165,19050264,19055754,19057511,19064572,19072831,19075230,19079342,19079986,19103758,19107233,19114656,19116269,19125794,19147772,19158375,19164214,19168705,19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IYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV,NP_001291647.1|MMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV,XP_006717989.1|MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVSCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV,XP_011538283.1|MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKQR,XP_011538284.1|MLLLKSVMIAFRKISKLLFQSKKFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
83	STK11	6794		STK11	LKB1|PJS|hLKB1	human	NM_000455.4,XM_005259617.1,XM_005259618.3,XM_011528209.1,XR_936204.1	NP_000446.1,XP_005259674.1,XP_005259675.1,XP_011526511.1	NC_000019.10,NC_018930.2,NG_007460.2,NT_011295.12,NW_004929412.1	A0A0S2Z4D1,Q15831	Nucleus.  Cytoplasm.	NULL				Hs.515005	2563227,8889548,8988175,9425897,9428765,9537235,9760200,9837816,10208439,10362809,10408777,10508479,10642499,10642527,11297520,11430832,11445556,11668633,11733352,11741830,11853558,12097271,12218179,12234250,12477932,12489981,12533684,12552571,12595760,12753905,12805220,12847291,12879020,12912948,14511394,14511408,14517247,14517248,14668798,14676191,14702039,14976552,14985505,15077168,15121768,15183188,15188174,15231735,15287029,15292028,15331174,15485651,15489334,15561763,15607222,15608654,15617552,15731909,15733851,15774015,15800014,15987703,16054041,16169070,16287113,16311241,16396636,16407220,16407837,16540748,16580634,16582077,16648371,16822578,16882735,16912160,16927138,16953221,17010524,17026623,17098823,17108107,17114342,17212587,17216128,17234589,17244606,17319781,17344591,17384680,17573348,17575127,17599048,17637250,17641416,17676035,17711506,17766436,17884763,17921699,17928927,17950019,18000088,18029348,18199157,18245474,18256292,18303014,18311138,18321849,18403917,18483235,18495044,18594528,18600394,18676680,18681789,18687677,18794113,18854309,18854318,19029933,19056867,19068194,19145097,19165201,19170196,19177591,19204826,19229701,19250387,19287990,19340305,19351817,19369417,19386264,19407487,19414597,19463221,19507030,19513107,19520843,19584313,19615099,19615732,19622832,19625176,19692168,19724060,19727776,19892943,19908348,20010869,20018878,20020146,20057966,20082862,20193846,20207041,20227367,20301443,20354225,20357370,20368287,20368693,20400510,20418665,20423848,20424326,20428811,20435009,20452353,20489196,20497868,20559149,20562859,20623358,20668229,20682687,20686846,20722467,20818976,20864035,20881644,20939895,20956321,20974850,21048031,21102257,21118512,21150337,21191146,21191700,21192934,21241696,21396365,21450399,21516116,21532627,21572398,21706049,21816872,21832049,21860411,21876548,21994947,22005930,22118009,22168747,22226967,22265968,22270359,22384927,22412893,22457270,22460425,22487816,22543132,22575644,22635025,22775437,22814264,22848740,22928647,22939624,22942091,22983157,22986809,22988252,23027127,23044421,23074285,23086944,23207623,23322200,23367447,23393134,23399955,23415580,23430953,23451056,23526220,23572524,23584481,23592276,23612973,23637231,23645358,23648482,23664447,23679304,23706335,23788249,23810581,23861764,23878245,23883619,23892522,23995788,24022664,24037887,24074562,24086281,24146957,24154639,24170201,24285539,24324551,24362629,24387336,24419424,24468202,24469340,24550282,24552808,24604241,24615515,24645967,24647869,24652667,24676538,24722282,24770722,24792998,24793789,24828662,24913037,24928005,24998845,25011082,25036637,25042259,25042806,25114112,25122068,25155037,25175672,25178656,25179843,25180605,25224251,25241761,25244018,25263448,25329316,25349262,25362209,25399650,25465874,25510663,25640309,25650664,25674212,25694554,25695224,25728766,25751324,25769882,25852190,25874445,25874865,25894929,26186194,26413869,26479318,26871637	15		NP_000446.1|MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGRAPNPARKACSASSKIRRLSACKQQ,XP_005259674.1|MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFTVPGPRRGGQSQWTAPGPPQGRVYERHRGGAAEHQIQGGGPGPQPCPQGLLRQQQDPPAVGLQAAVRLAACSPCPGAPPGARARPSVFLPVPPALPERWPPCFCADHAPGPPERPAGPGRGTAGTGRSPPPSAARQCTRLVDFAAPGGAFPGGRGRREAASMHFMWRLLAPPVASCSAGRPAPSGGPAADQLAGVETRLLTPPCMQRHLEAARPLWFFVWLVPFSFFLFFFKKK,XP_005259675.1|MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFTVPGGEEASEAGLRAERGLQKSEGSDLSGEEASRPAPQ,XP_011526511.1|MGSCRPGAVTHESKRSRPSWPTWEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFTVPGPRRGGQSQWTAPGPPQGRVYERHRGGAAEHQIQGGGPGPQPCPQGLLRQQQDPPAVGLQAAVRLAACSPCPGAPPGARARPSVFLPVPPALPERWPPCFCADHAPGPPERPAGPGRGTAGTGRSPPPSAARQCTRLVDFAAPGGAFPGGRGRREAASMHFMWRLLAPPVASCSAGRPAPSGGPAADQLAGVETRLLTPPCMQRHLEAARPLWFFVWLVPFSFFLFFFKKK
84	SESN1	27244	Sestrin-1	SESN1	PA26|SEST1	human	NM_001199933.1,NM_001199934.1,NM_014454.2	NP_001186862.1,NP_001186863.1,NP_055269.1	NC_000006.12,NC_018917.2,NG_029518.1,NT_025741.16,NW_004929328.1	Q9Y6P5	Nucleus.	NULL			Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth. {ECO:0000269|PubMed:15105503}.	Hs.591336	7938006,8889548,9926927,12477932,12607115,14702039,15105503,16751804,18692468,18703169,19704005,20800603,21067298,22658674,23274085,23535732,24587596	15		NP_001186862.1|MRLAAAANEAYTAPLAVSGLLGCKQCGGGRDQDEELGIRIPRPLGQGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELLYALRAITRYMT,NP_001186863.1|MHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELLYALRAITRYMT,NP_055269.1|MAEGENEVRWDGLCSRDSTTRETALENIRQTILRKTEYLRSVKETPHRPSDGLSNTESSDGLNKLLAHLLMLSKRCPFKDVREKSEFILKSIQELGIRIPRPLGQGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELLYALRAITRYMT
85	SESN2	83667	Sestrin-2	SESN2	HI95|SES2|SEST2	human	NM_031459.4,XR_946773.1	NP_113647.1	NC_000001.11,NC_018912.2,NT_032977.10,NW_004929289.1	P58004	NULL	NULL			Involved in the reduction of peroxiredoxins. {ECO:0000269|PubMed:15105503}.	Hs.469543	11230166,11256614,12203114,12477932,12607115,14702039,15105503,15489334,16344560,19113821,19377293,21418191,21536039,21988832,22363791,22450766,22749810,22982090,23238567,23274085,23383273,23916134,24046361,24825887,24838122,24947615,25024286,25040165,25378405,25457612,25572852,25692450,25716320,25778901,25802279,25819761,25962159,26133704,26186194,26449471,26586190	15		NP_113647.1|MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAESLEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPSADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT
86	ABL1	25		ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	human	NM_005157.5,NM_007313.2	NP_005148.2,NP_009297.2	NC_000009.12,NC_018920.2,NG_012034.1,NT_008470.20,NW_004929367.1	A0A024R8E2,P00519,Q59FK4	NULL	NULL				Hs.431048	1281542,1379745,1383690,1505033,1538749,1571536,1712671,1857987,1868241,2163052,2179820,2183353,2193202,2542016,2678002,2687768,2825022,2989692,2989703,3021337,3023859,3313010,3471171,4062888,6191223,6281890,6302194,6316147,6319012,6323103,7493940,7512963,7533294,7545908,7565761,7590236,7665185,7760813,7780740,7828850,7892170,7926767,7968380,8112292,8114715,8194526,8242749,8294442,8438166,8453102,8524328,8590002,8626527,8626543,8629002,8630736,8668148,8668151,8692915,8810278,8875975,8879209,8943360,8978305,9006901,9008161,9010225,9037071,9067577,9071815,9111318,9144171,9168116,9168117,9174058,9195915,9211900,9312071,9315092,9334312,9346925,9356459,9407116,9461559,9478921,9480911,9516488,9583676,9593709,9603926,9632734,9632788,9642287,9698566,9710592,9747873,9774693,9798959,9820532,9822717,9872323,9949177,10187839,10194451,10212258,10372803,10391249,10391250,10391251,10455176,10488096,10518561,10567556,10571082,10574931,10608806,10629029,10635328,10637231,10679771,10688886,10708759,10713049,10713716,10753870,10777567,10829062,10837221,10849448,10892742,10896159,10945997,10967110,10970852,10988075,11021760,11024037,11071635,11120811,11121037,11163214,11266449,11278340,11279131,11309382,11350980,11374898,11375976,11380621,11390389,11418237,11420673,11423618,11431473,11494128,11494134,11509666,11593427,11598012,11708318,11741929,11779715,11780146,11781820,11790798,11827972,11840343,11853795,11891774,11955625,11956190,11971963,12021275,12024016,12107171,12110584,12130510,12130516,12138893,12144533,12149456,12167702,12198159,12220663,12374288,12374739,12379115,12379650,12384576,12393636,12408765,12445832,12468540,12475393,12477932,12505259,12522270,12525554,12543778,12556557,12560071,12569093,12573241,12623848,12626632,12637538,12650908,12654250,12663457,12665579,12672821,12681507,12764153,12777393,12777400,12781448,12810679,12824179,12890867,12893824,12921956,12928501,12944467,12950161,12952226,14527680,14534537,14581377,14604282,14657955,14670960,14679214,14708008,14725908,14745431,14966468,14993251,15143187,15175272,15361874,15448168,15481444,15542838,15556646,15583852,15588985,15591787,15608616,15626746,15657060,15657136,15661746,15686624,15696159,15716990,15723338,15735728,15735735,15857938,15886098,15923648,15937340,15961388,16014719,16091742,16109371,16135792,16151465,16158059,16199863,16205638,16219545,16273093,16386788,16397227,16410245,16443220,16448696,16543148,16630659,16631755,16636310,16648821,16678104,16723087,16831423,16867995,16888623,16899465,16912036,16955467,16966279,16998483,17081983,17101133,17112510,17126298,17129785,17160020,17192257,17196995,17237826,17252009,17254966,17268511,17303698,17318191,17339230,17347407,17349636,17352427,17366548,17374743,17409407,17470729,17470736,17474147,17486070,17525531,17541395,17570524,17579186,17587335,17597804,17599053,17604596,17620332,17623672,17626041,17638918,17695727,17710227,17761812,17762503,17764157,17768119,17804707,17888034,17889935,17893873,17925491,17928051,17943163,17956664,17972958,18029348,18036399,18059481,18067320,18070606,18082628,18089786,18095154,18155796,18161990,18180382,18235045,18262060,18280240,18287094,18305217,18305550,18328268,18339898,18362889,18369471,18391983,18401414,18406870,18413724,18427551,18480060,18480061,18490454,18538733,18546844,18559503,18603549,18614052,18619508,18687796,18704194,18765637,18771174,18775312,18784740,18794796,18809728,18827185,18835194,18936177,18950845,19001122,19016792,19020542,19048492,19052872,19061839,19075013,19108887,19124506,19135771,19156526,19180499,19203793,19234221,19260121,19261608,19275932,19285032,19290927,19295548,19332026,19357699,19363261,19369965,19380743,19383348,19423701,19427856,19442657,19470755,19531213,19542604,19557636,19571320,19608682,19625707,19643477,19652056,19657362,19658100,19660459,19679652,19697154,19700222,19724931,19738611,19768693,19789182,19818398,19823681,19829692,19833721,19876398,19891780,19897486,19906645,19914245,19931180,19953087,19954044,19968720,20007699,20010464,20038234,20056178,20073070,20079431,20082857,20124512,20152788,20201926,20234815,20367437,20425353,20452982,20453000,20482842,20512393,20563669,20581864,20585028,20585556,20595523,20598684,20629032,20633771,20675402,20697350,20697894,20717963,20724541,20798688,20823226,20841568,20861316,20863169,20937825,20974687,21045136,21071472,21072043,21129254,21156844,21183952,21203397,21209200,21220745,21221851,21239056,21248063,21266020,21320496,21321929,21368377,21388681,21435002,21454413,21455220,21461967,21480391,21504383,21527514,21591355,21641753,21674858,21693657,21694468,21715626,21764785,21781306,21888027,21892207,21900237,21903771,21935931,21960589,21961412,21998569,22001646,22014333,22038725,22054731,22089930,22140458,22184410,22231445,22233112,22238610,22252550,22311485,22314255,22327125,22327338,22334513,22378042,22380496,22401567,22447844,22454521,22462553,22471662,22526369,22590567,22591684,22593461,22632162,22649097,22665066,22693568,22733220,22782217,22783572,22787435,22833565,22847163,22865780,22870928,22879933,22939624,22939629,22952603,22957062,22974441,22976291,22988030,23006999,23009571,23044928,23053188,23062104,23062378,23065514,23087049,23117882,23124138,23130349,23146907,23171811,23201011,23207522,23223358,23269583,23277196,23287430,23289360,23289634,23303187,23316053,23318434,23319661,23325923,23383002,23428668,23433665,23448894,23458731,23513809,23575066,23602568,23626584,23667855,23691243,23716543,23723070,23740246,23749639,23788109,23799845,23831022,23840065,23842646,23852372,23872305,23892407,23894305,23928308,23934627,23950177,23959873,23974192,23980151,24041959,24112389,24140708,24177958,24190424,24223753,24262285,24269846,24317448,24367707,24392933,24412932,24421390,24456693,24487968,24520051,24522549,24550512,24617663,24658140,24700464,24728074,24775308,24779036,24836440,24837466,24856998,24872081,24891505,24903628,24939418,24947832,24967705,25036192,25045550,25052580,25068103,25074247,25132497,25134459,25213664,25219501,25233427,25248240,25293778,25368164,25402006,25527259,25561363,25615000,25620702,25624478,25644089,25648025,25730044,25740611,25756742,25769542,25795725,25852190,25883211,25944899,25997600,25999467,26072332,26087013,26126715,26152360,26179066,26186983,26203192,26217035,26344197,26496610	15		NP_005148.2|MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR,NP_009297.2|MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR
87	BCR	613	Breakpoint cluster region protein	BCR	ALL|BCR1|CML|D22S11|D22S662|PHL	human	NM_004327.3,NM_021574.2	NP_004318.3,NP_067585.2	NC_000022.11,NC_018933.2,NG_009244.1,NT_011520.13,NW_004929430.1	P11274	NULL	NULL			GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity. {ECO:0000269|PubMed:1657398, ECO:0000269|PubMed:1903516}.	Hs.517461,Hs.715409	1317490,1383690,1657398,1706781,1712671,1763041,1868241,1900918,1903516,2193202,2263470,2407300,2678002,2820585,2825022,2915904,2989692,2989703,3023859,3107980,3118359,3194194,3285291,3422516,3463934,3540951,6281890,6316147,6319012,6584200,7506601,7529874,7534286,7606002,7665185,7724587,7939633,8112292,8195176,8204871,8453102,8502487,8621719,8622703,8756631,8757502,8943292,8955135,8978305,8995379,9053848,9071815,9174058,9178913,9209414,9211920,9407116,9467953,9535855,9566916,9747873,9788431,9822717,9872323,9874796,9949177,10194128,10403766,10508479,10706130,10849448,10887126,10887132,11069024,11376433,11726515,11746971,11780146,11790798,12023981,12096337,12114534,12115002,12144533,12145699,12370803,12393433,12408765,12477932,12522270,12543778,12556557,12560071,12586822,12592324,12734675,12764153,12781448,12808105,12821944,12890867,14534537,14581377,14654084,14656881,14702039,14725908,14961028,14966468,14993251,15123239,15143164,15144186,15145216,15248918,15389825,15481444,15489334,15494376,15542838,15626746,15684424,15716990,15723338,15735728,15857938,15866548,15968309,16045749,16079118,16116902,16169070,16264277,16418324,16442529,16442619,16449534,16469868,16481037,16490599,16494625,16502579,16502580,16543472,16596225,16598834,16631477,16670264,16723087,16778200,16825666,16849647,16855631,16888785,16912036,16914906,16955467,16966279,16998483,16999686,17018862,17081983,17090304,17102890,17110338,17145570,17196995,17303698,17314511,17347407,17349636,17374743,17579186,17597804,17638851,17638918,17643375,17710227,17762503,17768128,17822820,17928051,17934518,17939855,18070886,18082628,18227349,18246120,18287094,18354488,18385754,18391951,18406870,18406872,18474292,18495245,18503828,18538733,18549649,18603297,18603549,18617057,18676680,18704194,18784740,18794796,18809762,18827185,18976975,19020542,19048492,19056867,19061839,19067742,19135771,19170196,19203346,19240172,19261608,19295548,19369965,19380743,19557636,19571320,19608682,19615732,19619277,19625176,19625707,19652056,19692168,19718053,19724931,19840940,19876398,19911011,19946888,20007699,20010464,20015884,20028985,20038234,20141430,20207846,20304029,20351714,20379614,20442314,20452982,20463552,20520635,20607847,20633771,20675402,20697350,20717963,20739956,21045136,21124777,21156844,21183952,21203397,21239056,21248063,21266020,21310073,21330459,21489624,21504383,21641753,21674858,21693761,21706016,21762985,21764785,21895409,21900237,21903771,21908428,21935931,21960589,22153077,22184410,22230800,22231445,22233112,22327125,22384256,22447844,22471662,22526369,22542470,22587422,22591684,22593461,22665066,22772060,22782217,22787435,22847163,22889411,22896000,22952844,22957062,23047475,23062104,23062378,23065514,23086624,23124138,23171834,23207522,23211419,23223358,23269583,23277196,23287430,23289360,23317202,23382219,23396943,23428668,23455922,23458731,23547655,23588714,23604228,23716543,23788109,23799845,23894305,23934627,23940119,23950177,23974192,23980151,24189400,24262285,24269846,24456693,24487968,24550512,24675360,24779036,24836440,24856998,24903628,24967705,24998540,25132497,25134459,25213664,25217883,25241761,25293778,25379619,25479544,25520136,25615000,25631082,25644089,25648025,25721898,25730044,25740611,25756742,25769542,25876659,25921289,26087013,26179066,26186194,26186983,26496610,26638075,26673895	15		NP_004318.3|MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV,NP_067585.2|MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNELDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV
88	CASP3	836	Caspase-3 subunit p12	CASP3	CPP32|CPP32B|SCA-1	human	NM_004346.3,NM_032991.2,XM_011532301.1	NP_004337.2,NP_116786.1,XP_011530603.1	NC_000004.12,NC_018915.2,NT_016354.20,NW_004929320.1	P42574	Cytoplasm.	NULL			Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. {ECO:0000269|PubMed:21357690, ECO:0000269|PubMed:7596430}.	Hs.141125	1067155,7596430,7774019,7983002,8044845,8605870,8626669,8673606,8689682,8696339,8755496,8780721,8804412,8812467,8900201,8943232,8962078,8976194,9021152,9045680,9108473,9115219,9206994,9208847,9219695,9230442,9233763,9235961,9252332,9267021,9278461,9298992,9323209,9326610,9334214,9334240,9334338,9337844,9348292,9351817,9353287,9361003,9367996,9368003,9384571,9395403,9422780,9452471,9525868,9535906,9545236,9548463,9593687,9618490,9624143,9632733,9660939,9671712,9685336,9694885,9705209,9708895,9736630,9751706,9786869,9796814,9799125,9811849,9840926,9850056,9857079,9875225,9878167,9894612,9933635,9990034,10022118,10066732,10069390,10082566,10103059,10200531,10205158,10205159,10319819,10364179,10409750,10430052,10432301,10435619,10438581,10454555,10469173,10479680,10490026,10510468,10521396,10556977,10564664,10579725,10602493,10602513,10608812,10611247,10629060,10671544,10672017,10675528,10704341,10708425,10712510,10713703,10734073,10748026,10770929,10777594,10791974,10799874,10821855,10823823,10862606,10896157,10899937,10921886,10926122,10942389,10998058,11016947,11024045,11042212,11053413,11058115,11076937,11084335,11098060,11106668,11123279,11141237,11149901,11162250,11162351,11170436,11175261,11177389,11222676,11230124,11242052,11248093,11257230,11257232,11261798,11274152,11278283,11278287,11278424,11278572,11278782,11278797,11283607,11313965,11331419,11345898,11350920,11356849,11359776,11387340,11399776,11420704,11423904,11425872,11437602,11438643,11447297,11462036,11470874,11478781,11479289,11500511,11509621,11514563,11517310,11526478,11550094,11551979,11555640,11602184,11675509,11689006,11696595,11741893,11748221,11752060,11752215,11787859,11788610,11795487,11802788,11815631,11825902,11830582,11832478,11840332,11854437,11859414,11866986,11875078,11901153,11904443,11927604,11948397,11960384,11972398,11981455,11988074,11989976,11992386,12004072,12019321,12032677,12036886,12044963,12055227,12070005,12070657,12080079,12095993,12107159,12112012,12118383,12124386,12145703,12149654,12150947,12151338,12169388,12181128,12181742,12186978,12190962,12207967,12210761,12228224,12235123,12297281,12390838,12393901,12397210,12401855,12404116,12425945,12438416,12444137,12477932,12483536,12490308,12511568,12515825,12566444,12576296,12576443,12579342,12581734,12598529,12605885,12606589,12611892,12621124,12624662,12643601,12657644,12677451,12686427,12700630,12700660,12707329,12750393,12750404,12760639,12787561,12788227,12788938,12792782,12804035,12809603,12821118,12824190,12833566,12837287,12854132,12867600,12874324,12888622,12897143,14555204,14570914,14572611,14612448,14623896,14657946,14674699,14678329,14684629,14710359,14764700,14960581,14970175,14971566,14976035,14982947,14991812,14993250,15014070,15015772,15033720,15033815,15041704,15087450,15098015,15153940,15156398,15178331,15179054,15186778,15187159,15200957,15204919,15205454,15220451,15241180,15246206,15254227,15258591,15280469,15345747,15375594,15473998,15489334,15505416,15507451,15542841,15564512,15569669,15569672,15569692,15578977,15599395,15617521,15637055,15638357,15650747,15657349,15657356,15670787,15705385,15706351,15716280,15725353,15735701,15748158,15748808,15767427,15803189,15806167,15843892,15848173,15869582,15935070,15996160,16009347,16080782,16083554,16111829,16120388,16121124,16179347,16203739,16204230,16213496,16227597,16242324,16286477,16300929,16320828,16330530,16337360,16338743,16344560,16382148,16455648,16463650,16480911,16498457,16501604,16505307,16511342,16516911,16520893,16526059,16529748,16530181,16530191,16543147,16567804,16651613,16689860,16716256,16781734,16787777,16791842,16802364,16808908,16835231,16869888,16882668,16884727,16894574,16897667,16931214,16935258,16948902,16949642,16955788,16977583,16979168,16983089,17008916,17013756,17013758,17023557,17038954,17065568,17069460,17071630,17080552,17114647,17118559,17121821,17123522,17124493,17130234,17140287,17141888,17143787,17167422,17172814,17198755,17217622,17219053,17235653,17245643,17261582,17272816,17283187,17291493,17301822,17321792,17324936,17337451,17340613,17364171,17379327,17412564,17413988,17430778,17436592,17437405,17462862,17488272,17495975,17498346,17505517,17525639,17534194,17544405,17559062,17597071,17606719,17606900,17616526,17645689,17653867,17689858,17698513,17721932,17724022,17805550,17823127,17880920,17908973,17928446,17936584,17950632,17967742,17978580,17981569,17983802,17989718,18000616,18029348,18047842,18054197,18055116,18058802,18060501,18074388,18083346,18086147,18088367,18092356,18155705,18155731,18164959,18171980,18209072,18211414,18227733,18256758,18256791,18266005,18296636,18297401,18298948,18300076,18309324,18330265,18379198,18381704,18384375,18415681,18415689,18427836,18439040,18441516,18450750,18473402,18476631,18521960,18551626,18561948,18577580,18585351,18586680,18623086,18652315,18658137,18669646,18676680,18708163,18712678,18723680,18727869,18754867,18759060,18763039,18768468,18814044,18818379,18820371,18821563,18829519,18838202,18844072,18946722,18986328,19013323,19035131,19043361,19046417,19052714,19058789,19074885,19132366,19141860,19157504,19157506,19159073,19170196,19178812,19200347,19204086,19219602,19223905,19236754,19240112,19241192,19244543,19258326,19266703,19269008,19270727,19272183,19275584,19275586,19275587,19281794,19283487,19289465,19299722,19319745,19322201,19351510,19355923,19379562,19404232,19414860,19453261,19458171,19513559,19519609,19531679,19544333,19549685,19550122,19553679,19557639,19559790,19567200,19570417,19573080,19585117,19598027,19604093,19610261,19625176,19626422,19636556,19655253,19655254,19655415,19665028,19692168,19692467,19698783,19698994,19713971,19715609,19723039,19724860,19724907,19730442,19738422,19759058,19770576,19770581,19773279,19774677,19784808,19788069,19788411,19807657,19812265,19826114,19838207,19840460,19854241,19878567,19895210,19913121,19925402,19937139,19942343,19956888,19996122,19996272,19996275,19996278,20001963,20012528,20025478,20038816,20041182,20042134,20045442,20060927,20063052,20068062,20072652,20085765,20087649,20101263,20103643,20104682,20142237,20150439,20180022,20198319,20227371,20299368,20307198,20340172,20346214,20383567,20402676,20404718,20423928,20424172,20450729,20453000,20492341,20512574,20530714,20566630,20580881,20598358,20619728,20628086,20628645,20632819,20644561,20661084,20665667,20667824,20683021,20683843,20702410,20722551,20723300,20738749,20801175,20814064,20839416,20855536,20856198,20862799,20919853,20929126,20947770,20950443,20959405,20962079,20966960,20981869,21029675,21048031,21081164,21098975,21099290,21099299,21123175,21123558,21142842,21148072,21151026,21160486,21178828,21203962,21216952,21223758,21237154,21248767,21255440,21270757,21307660,21317880,21319273,21382445,21437568,21441410,21479362,21483469,21483669,21484410,21504623,21506333,21548803,21555338,21561870,21624464,21644054,21644232,21667042,21668377,21671484,21682651,21700414,21706480,21724551,21725926,21726810,21729540,21756903,21775054,21785112,21802116,21819468,21827945,21859712,21869592,21875325,21880013,21914347,21923740,21926353,21944661,21959934,21987091,21988832,22013052,22072751,22094081,22121772,22136337,22147199,22184067,22191568,22216281,22238643,22242595,22298410,22302483,22309278,22320973,22429811,22429842,22451931,22482362,22489116,22496955,22504224,22541080,22552851,22568453,22607239,22629415,22678593,22683311,22764223,22796265,22815893,22832123,22837201,22844442,22872644,22885173,22912727,22926545,22931643,22939953,22944165,22949938,22951837,22952982,22964638,23049853,23054082,23074197,23103707,23109891,23122728,23152053,23156805,23170075,23170789,23202514,23220614,23221544,23271051,23271418,23295106,23326121,23343959,23345589,23359247,23364796,23384723,23386603,23416147,23421973,23460086,23503461,23519117,23531593,23531848,23545262,23555267,23563149,23568731,23591201,23599180,23616419,23650375,23658722,23686572,23703388,23708668,23724505,23728617,23729654,23732112,23765963,23775301,23781587,23791066,23846227,23867824,23892923,23894522,23900644,23907941,23949910,23954828,23979166,24009453,24028796,24058658,24104479,24113184,24122846,24123326,24129493,24161344,24204256,24252910,24265318,24268429,24338704,24347041,24362034,24363090,24418364,24434142,24434746,24466265,24496691,24553140,24561085,24573549,24583153,24607276,24691971,24764681,24792179,24810056,24810717,24839934,24842904,24903211,24917042,24952432,24969479,24980229,25002346,25037599,25041019,25058423,25058453,25068691,25112874,25124665,25156550,25177685,25180606,25197379,25241761,25246356,25343534,25352594,25435190,25467409,25476481,25531894,25578648,25619400,25645462,25662045,25665064,25689150,25738796,25744832,25748204,25800561,25806508,25821312,25866249,25887904,25909216,25943894,26014377,26045308,26055088,26064904,26109071,26161867,26186194,26257207,26334686,26344197,26526615	15		NP_004337.2|MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH,NP_116786.1|MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH,XP_011530603.1|MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
89	EIF4E	1977		EIF4E	AUTS19|CBP|EIF4E1|EIF4EL1|EIF4F|eIF-4E	human	NM_001130678.1,NM_001130679.1,NM_001968.3,XM_006714126.2,XM_006714127.2	NP_001124150.1,NP_001124151.1,NP_001959.1,XP_006714189.1,XP_006714190.1	NC_000004.12,NC_018915.2,NG_047048.1,NT_016354.20,NW_004929320.1	D6RBW1,P06730,Q32Q75,X5D7E3	NULL	NULL				Hs.249718	1384058,1672854,1674733,1736299,1916814,1993647,2016328,3112145,3469651,7590282,7651417,7665584,7782323,7935836,8449919,8505316,8521827,8662663,8816458,8939971,9155017,9330633,9372926,9418880,9593750,9607624,9628874,9878069,10022874,10364159,10394359,10405182,10600798,10648556,10698949,10753870,10772338,10856257,10870064,10880459,10910074,11072066,11154262,11401917,11408474,11500381,11553333,11575918,11605658,11771728,11847216,11879179,11959093,12071973,12089333,12105188,12138083,12151318,12167712,12169454,12186496,12189553,12239292,12374671,12438698,12477932,12482586,12554669,12588972,12588975,12691746,12775419,12781867,12897141,12918105,12975586,14558943,14645512,14673156,14732354,14990584,15094042,15122903,15153109,15220445,15247416,15355912,15361857,15371741,15375804,15487973,15489334,15542544,15767663,15809305,15840819,15878868,15897904,15956551,15961545,16023599,16112647,16124648,16189514,16242075,16271312,16281055,16332685,16341674,16467844,16504179,16540463,16541103,16648488,16699599,16720573,16739988,16756390,16798736,16824195,17010208,17074885,17203162,17245113,17254965,17316564,17353931,17357517,17524464,17601486,17631896,17638893,17667941,17689990,17724079,17786246,17855553,18234281,18250159,18343217,18423201,18479935,18593934,18614538,18719964,18789325,18805096,18955708,18957614,19020722,19060904,19114552,19122207,19134194,19188486,19244480,19261348,19262567,19289374,19367274,19383915,19440045,19483468,19556253,19560264,19603014,19615732,19776122,19834456,19850923,19850929,20053821,20101233,20224576,20347422,20359850,20360068,20379614,20421305,20427534,20430826,20434207,20458337,20499137,20537983,20616046,20652449,20655307,20686366,21047768,21088106,21145089,21159249,21238947,21320304,21334199,21389327,21415224,21661078,21750861,21798997,21832049,21876152,21883093,21913890,21941146,21964297,21988832,21995271,22216185,22397984,22456335,22457629,22509910,22556409,22578813,22586265,22614784,22623428,22681889,22684010,22748716,22759308,22797067,22851180,22863883,22872150,22902403,22939629,23079111,23100465,23277284,23359369,23410891,23467026,23471078,23472659,23547259,23588929,23665580,23665581,23667251,23737503,23814182,23831578,23883783,23901100,23974830,24052408,24211447,24239466,24345331,24363449,24431103,24491247,24551240,24714040,24722188,24814906,24818597,24845562,24971752,25004955,25025927,25049413,25193863,25197055,25234597,25263391,25342548,25343550,25403230,25416956,25422161,25425688,25439783,25450520,25456498,25466251,25524901,25533957,25588502,25615552,25702871,25717031,25755728,25813250,25835715,25839159,25884680,25915158,25921289,25982998,25986608,26143374,26147685,26186194,26344197,26427906	15		NP_001124150.1|MLDLTSRGQVGTSRRMAEAACSAHFLETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV,NP_001124151.1|MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPKVLELQLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV,NP_001959.1|MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV,XP_006714189.1|MKKKQNKKERKKMRAEDGENDAIKKQAESLRESQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV,XP_006714190.1|MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPKVLELQV
90	daf-2	175410				nematode	NM_001312987.1,NM_001312988.1,NM_001312989.1,NM_001312990.1,NM_001312991.1,NM_065249.4,NR_132448.1	NP_001299916.1,NP_001299917.1,NP_001299918.1,NP_001299919.1,NP_001299920.1,NP_497650.4	NC_003281.10	A0A0K3ARE8,A0A0K3ARZ1,A0A0K3AUA1,A0A0K3AUY1,A0A0K3AXA0,Q968Y9	Membrane.	NULL				Cel.8775	7789761,8005442,8247153,9252323,9790527,9851916,10625546,11381260,12399591,12571101,12654727,12817143,14516929,14576426,14961122,15217602,15308663,15708444,15905404,16103914,16151516,16164423,16441841,16522328,16530049,16751106,16777605,16917064,16968739,17266680,17411345,17571923,17608836,17660533,17673661,17897480,18006689,18025456,18056973,18245374,18358814,18587389,18662544,18665238,18762027,18782349,18832074,18927620,18988854,19043800,19372390,19442682,19506556,19667176,19675139,19747231,19851507,19936206,19940149,20209166,20226839,20392130,20461074,20502519,20523893,20550516,20613724,20946987,21040400,21129974,21343369,21408062,21441213,21471153,21531333,21723504,21749693,21907144,22116032,22123849,22445852,22560223,22562940,22672310,23049887,23247094,23262285,23566034,23791175,23820781,24120884,24555535,24671263,25035490,25048458,25469508	5		NP_001299916.1|MTRMNIVRCRRRHKILENLEEENLGPSCSSTTSTTAATEALGTTTEDMRLKQQRSSSRATEHDIVDGNHHDDEHITMRRLRLVKNSRTRRRTTPDSSMDCYEENPPSQKTSINYSWISKKSSMTSLMLLLLFAFVQPCASIVEKRCGPIDIRNRPWDIKPQWSKLGDPNEKDLAGQRMVNCTVVEGSLTISFVLKHKTKAQEEMHRSLQPRYSQDEFITFPHLREITGTLLVFETEGLVDLRKIFPNLRVIGGRSLIQHYALIIYRNPDLEIGLDKLSVIRNGGVRIIDNRKLCYTKTIDWKHLITSSINDVVVDNAAEYAVTETGLMCPRGACEEDKGESKCHYLEEKNQEQGVERVQSCWSNTTCQKSCAYDRLLPTKEIGPGCDANGDRCHDQCVGGCERVNDATACHACKNVYHKGKCIEKCDAHLYLLLQRRCVTREQCLQLNPVLSNKTVPIKATAGLCSDKCPDGYQINPDDHRECRKCVGKCEIVCEINHVIDTFPKAQAIRLCNIIDGNLTIEIRGKQDSGMASELKDIFANIHTITGYLLVRQSSPFISLNMFRNLRRIEAKSLFRNLYAITVFENPNLKKLFDSTTDLTLDRGTVSIANNKMLCFKYIKQLMSKLNIPLDPIDQSEGTNGEKAICEDMAINVSITAVNADSVFFSWPSFNITDIDQRKFLGYELFFKEVPRIDENMTIEEDRSACVDSWQSVFKQYYETSNGEPTPDIFMDIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSKIGFVRTSYYTPDPPTLALAQVDSDAIHITWEAPLQPNGDLTHYTIMWRENEVSPYEEAEKFCTDASTPANRQHTKDPKETIVADKPVDIPSSRTVAPTLLTMMGHEDQQKTCAATPGCCSCSAIEESSEQNKKKRPDPMSAIESSAFENKLLDEVLMPRCDIKNDPVGCAMLLLPPEIDDSDVGDDDEEPGGGSEQQQRILRNSEILKRQKRQILGRSLGGIHGIRSIGRKEYEQFADMILDTMRVRRSIEDANRVSEELEKAENLGKAPKTLGGKKPLIHISKKKPSSSSTTSTPAPTIASMYALTRKPTTVPGTRIRLYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPGASCSISHRAGALKRTKHITDIDKVLNETIEWRFMNNSQQVNVTWDPPTEVNGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGAGPEAESSDPIVVMTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVRYGKKVKALSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEALDLDDIDDTDMNDQVVEVAPDVENVEVQSDSERRNTDSIPLKQFKTIPPINATTSHSTISIDETPMKAKQREGSLDEEYALMNHSGGPSDAEVRTYAGDGDYVERDVRENDVPTRRNTGASTSSYTGGGPYCLTNRGGSNERGAGFGEAVRLTDGVGSGHLNDDDYVEKEISSMDTRRSTGASSSSYGVPQTNWSGNRGATYYTSKAQQAATAAAAAAAALQQQQNGGRGDRLTQLPGTGHLQSTRGGQDGDYIETEPKNYRNNGSPSRNGNSRDIFNGRSAFGENEHLIEDNEHHPLV,NP_001299917.1|MRLKQQRSSSRATEHDIVDGNHHDDEHITMRRLRLVKNSRTRRRTTPDSSMDCYEENPPSQKTSINYSWISKKSSMTSLMLLLLFAFVQPCASIVEKRCGPIDIRNRPWDIKPQWSKLGDPNEKDLAGQRMVNCTVVEGSLTISFVLKHKTKAQEEMHRSLQPRYSQDEFITFPHLREITGTLLVFETEGLVDLRKIFPNLRVIGGRSLIQHYALIIYRNPDLEIGLDKLSVIRNGGVRIIDNRKLCYTKTIDWKHLITSSINDVVVDNAAEYAVTETGLMCPRGACEEDKGESKCHYLEEKNQEQGVERVQSCWSNTTCQKSCAYDRLLPTKEIGPGCDANGDRCHDQCVGGCERVNDATACHACKNVYHKGKCIEKCDAHLYLLLQRRCVTREQCLQLNPVLSNKTVPIKATAGLCSDKCPDGYQINPDDHRECRKCVGKCEIVCEINHVIDTFPKAQAIRLCNIIDGNLTIEIRGKQDSGMASELKDIFANIHTITGYLLVRQSSPFISLNMFRNLRRIEAKSLFRNLYAITVFENPNLKKLFDSTTDLTLDRGTVSIANNKMLCFKYIKQLMSKLNIPLDPIDQSEGTNGEKAICEDMAINVSITAVNADSVFFSWPSFNITDIDQRKFLGYELFFKEVPRIDENMTIEEDRSACVDSWQSVFKQYYETSNGEPTPDIFMDIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSKIGFVRTSYYTPDPPTLALAQVDSDAIHITWEAPLQPNGDLTHYTIMWRENEVSPYEEAEKFCTDASTPANRQHTKDPKETIVADKPVDIPSSRTVAPTLLTMMGHEDQQKTCAATPGCCSCSAIEESSEQNKKKRPDPMSAIESSAFENKLLDEVLMPRDTMRVRRSIEDANRVSEELEKAENLGKAPKTLGGKKPLIHISKKKPSSSSTTSTPAPTIASMYALTRKPTTVPGTRIRLYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPGASCSISHRAGALKRTKHITDIDKVLNETIEWRFMNNSQQVNVTWDPPTEVNGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGAGPEAESSDPIVVMTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVRYGKKVKALSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEALDLDDIDDTDMNDQVVEVAPDVENVEVQSDSERRNTDSIPLKQFKTIPPINATTSHSTISIDETPMKAKQREGSLDEEYALMNHSGGPSDAEVRTYAGDGDYVERDVRENDVPTRRNTGASTSSYTGGGPYCLTNRGGSNERGAGFGEAVRLTDGVGSGHLNDDDYVEKEISSMDTRRSTGASSSSYGVPQTNWSGNRGATYYTSKAQQAATAAAAAAAALQQQQNGGRGDRLTQLPGTGHLQSTRGGQDGDYIETEPKNYRNNGSPSRNGNSRDIFNGRSAFGENEHLIEDNEHHPLV,NP_001299918.1|MRRLRLVKNSRTRRRTTPDSSMDCYEENPPSQKTSINYSWISKKSSMTSLMLLLLFAFVQPCASIVEKRCGPIDIRNRPWDIKPQWSKLGDPNEKDLAGQRMVNCTVVEGSLTISFVLKHKTKAQEEMHRSLQPRYSQDEFITFPHLREITGTLLVFETEGLVDLRKIFPNLRVIGGRSLIQHYALIIYRNPDLEIGLDKLSVIRNGGVRIIDNRKLCYTKTIDWKHLITSSINDVVVDNAAEYAVTETGLMCPRGACEEDKGESKCHYLEEKNQEQGVERVQSCWSNTTCQKSCAYDRLLPTKEIGPGCDANGDRCHDQCVGGCERVNDATACHACKNVYHKGKCIEKCDAHLYLLLQRRCVTREQCLQLNPVLSNKTVPIKATAGLCSDKCPDGYQINPDDHRECRKCVGKCEIVCEINHVIDTFPKAQAIRLCNIIDGNLTIEIRGKQDSGMASELKDIFANIHTITGYLLVRQSSPFISLNMFRNLRRIEAKSLFRNLYAITVFENPNLKKLFDSTTDLTLDRGTVSIANNKMLCFKYIKQLMSKLNIPLDPIDQSEGTNGEKAICEDMAINVSITAVNADSVFFSWPSFNITDIDQRKFLGYELFFKEVPRIDENMTIEEDRSACVDSWQSVFKQYYETSNGEPTPDIFMDIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSKIGFVRTSYYTPDPPTLALAQVDSDAIHITWEAPLQPNGDLTHYTIMWRENEVSPYEEAEKFCTDASTPANRQHTKDPKETIVADKPVDIPSSRTVAPTLLTMMGHEDQQKTCAATPGCCSCSAIEESSEQNKKKRPDPMSAIESSAFENKLLDEVLMPRDTMRVRRSIEDANRVSEELEKAENLGKAPKTLGGKKPLIHISKKKPSSSSTTSTPAPTIASMYALTRKPTTVPGTRIRLYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPGASCSISHRAGALKRTKHITDIDKVLNETIEWRFMNNSQQVNVTWDPPTEVNGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGAGPEAESSDPIVVMTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVRYGKKVKALSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEALDLDDIDDTDMNDQVVEVAPDVENVEVQSDSERRNTDSIPLKQFKTIPPINATTSHSTISIDETPMKAKQREGSLDEEYALMNHSGGPSDAEVRTYAGDGDYVERDVRENDVPTRRNTGASTSSYTGGGPYCLTNRGGSNERGAGFGEAVRLTDGVGSGHLNDDDYVEKEISSMDTRRSTGASSSSYGVPQTNWSGNRGATYYTSKAQQAATAAAAAAAALQQQQNGGRGDRLTQLPGTGHLQSTRGGQDGDYIETEPKNYRNNGSPSRNGNSRDIFNGRSAFGENEHLIEDNEHHPLV,NP_001299919.1|MWRENEVSPYEEAEKFCTDASTPANRQHTKDPKETIVADKPVDIPSSRTVAPTLLTMMGHEDQQKTCAATPGCCSCSAIEESSEQNKKKRPDPMSAIESSAFENKLLDEVLMPRDTMRVRRSIEDANRVSEELEKAENLGKAPKTLGGKKPLIHISKKKPSSSSTTSTPAPTIASMYALTRKPTTVPGTRIRLYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPGASCSISHRAGALKRTKHITDIDKVLNETIEWRFMNNSQQVNVTWDPPTEVNGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGAGPEAESSDPIVVMTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVRYGKKVKALSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEALDLDDIDDTDMNDQVVEVAPDVENVEVQSDSERRNTDSIPLKQFKTIPPINATTSHSTISIDETPMKAKQREGSLDEEYALMNHSGGPSDAEVRTYAGDGDYVERDVRENDVPTRRNTGASTSSYTGGGPYCLTNRGGSNERGAGFGEAVRLTDGVGSGHLNDDDYVEKEISSMDTRRSTGASSSSYGVPQTNWSGNRGATYYTSKAQQAATAAAAAAAALQQQQNGGRGDRLTQLPGTGHLQSTRGGQDGDYIETEPKNYRNNGSPSRNGNSRDIFNGRSAFGENEHLIEDNEHHPLV,NP_001299920.1|MTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVRYGKKVKALSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEALDLDDIDDTDMNDQVVEVAPDVENVEVQSDSERRNTDSIPLKQFKTIPPINATTSHSTISIDETPMKAKQREGSLDEEYALMNHSGGPSDAEVRTYAGDGDYVERDVRENDVPTRRNTGASTSSYTGGGPYCLTNRGGSNERGAGFGEAVRLTDGVGSGHLNDDDYVEKEISSMDTRRSTGASSSSYGVPQTNWSGNRGATYYTSKAQQAATAAAAAAAALQQQQNGGRGDRLTQLPGTGHLQSTRGGQDGDYIETEPKNYRNNGSPSRNGNSRDIFNGRSAFGENEHLIEDNEHHPLV,NP_497650.4|MTRMNIVRCRRRHKILENLEEENLGPSCSSTTSTTAATEALGTTTEDMRLKQQRSSSRATEHDIVDGNHHDDEHITMRRLRLVKNSRTRRRTTPDSSMDCYEENPPSQKTSINYSWISKKSSMTSLMLLLLFAFVQPCASIVEKRCGPIDIRNRPWDIKPQWSKLGDPNEKDLAGQRMVNCTVVEGSLTISFVLKHKTKAQEEMHRSLQPRYSQDEFITFPHLREITGTLLVFETEGLVDLRKIFPNLRVIGGRSLIQHYALIIYRNPDLEIGLDKLSVIRNGGVRIIDNRKLCYTKTIDWKHLITSSINDVVVDNAAEYAVTETGLMCPRGACEEDKGESKCHYLEEKNQEQGVERVQSCWSNTTCQKSCAYDRLLPTKEIGPGCDANGDRCHDQCVGGCERVNDATACHACKNVYHKGKCIEKCDAHLYLLLQRRCVTREQCLQLNPVLSNKTVPIKATAGLCSDKCPDGYQINPDDHRECRKCVGKCEIVCEINHVIDTFPKAQAIRLCNIIDGNLTIEIRGKQDSGMASELKDIFANIHTITGYLLVRQSSPFISLNMFRNLRRIEAKSLFRNLYAITVFENPNLKKLFDSTTDLTLDRGTVSIANNKMLCFKYIKQLMSKLNIPLDPIDQSEGTNGEKAICEDMAINVSITAVNADSVFFSWPSFNITDIDQRKFLGYELFFKEVPRIDENMTIEEDRSACVDSWQSVFKQYYETSNGEPTPDIFMDIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSKIGFVRTSYYTPDPPTLALAQVDSDAIHITWEAPLQPNGDLTHYTIMWRENEVSPYEEAEKFCTDASTPANRQHTKDPKETIVADKPVDIPSSRTVAPTLLTMMGHEDQQKTCAATPGCCSCSAIEESSEQNKKKRPDPMSAIESSAFENKLLDEVLMPRDTMRVRRSIEDANRVSEELEKAENLGKAPKTLGGKKPLIHISKKKPSSSSTTSTPAPTIASMYALTRKPTTVPGTRIRLYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPGASCSISHRAGALKRTKHITDIDKVLNETIEWRFMNNSQQVNVTWDPPTEVNGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGAGPEAESSDPIVVMTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVRYGKKVKALSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEALDLDDIDDTDMNDQVVEVAPDVENVEVQSDSERRNTDSIPLKQFKTIPPINATTSHSTISIDETPMKAKQREGSLDEEYALMNHSGGPSDAEVRTYAGDGDYVERDVRENDVPTRRNTGASTSSYTGGGPYCLTNRGGSNERGAGFGEAVRLTDGVGSGHLNDDDYVEKEISSMDTRRSTGASSSSYGVPQTNWSGNRGATYYTSKAQQAATAAAAAAAALQQQQNGGRGDRLTQLPGTGHLQSTRGGQDGDYIETEPKNYRNNGSPSRNGNSRDIFNGRSAFGENEHLIEDNEHHPLV
91	EGFR	1956		EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	human	NM_005228.3,NM_201282.1,NM_201283.1,NM_201284.1	NP_005219.2,NP_958439.1,NP_958440.1,NP_958441.1	NC_000007.14,NC_018918.2,NG_007726.3,NT_007819.18,NW_004929330.1	P00533	Secreted.	NULL				Hs.488293,Hs.605083	1281549,1301150,1309762,1322798,1333047,1334406,1372092,1382070,1383230,1385407,1501243,1505215,1623525,1633149,1647028,1651322,1689310,1706616,1808202,1850098,1988448,2173144,2176151,2434500,2543678,2543683,2790960,2810532,2984676,2985580,2987962,2991749,2991899,3039909,3138233,3329716,6093780,6297856,6324343,6325948,6326261,6328312,6330563,7506413,7510700,7518560,7527043,7532293,7535770,7540771,7542744,7543024,7588596,7592693,7623846,7640657,7654368,7657591,7657660,7673163,7682059,7685104,7690989,7693694,7730382,7736574,7761838,7782294,7797556,7880396,7903710,7993895,8034616,8125298,8305738,8413296,8493579,8497321,8577769,8596488,8610109,8610433,8621392,8638121,8639530,8647288,8647858,8650580,8657103,8662998,8702572,8729040,8798643,8810325,8845374,8875975,8885868,8887653,8918811,8940013,8940083,8943228,8962717,9006901,9020117,9049247,9050838,9050991,9079622,9103388,9115287,9121472,9130710,9188692,9207933,9233779,9307968,9344857,9346925,9355745,9356464,9362449,9363897,9374534,9416834,9419975,9425043,9430697,9447973,9480911,9488479,9506989,9506992,9507002,9528863,9535896,9544989,9556602,9617486,9642287,9658162,9710451,9733788,9737977,9756944,9781061,9815893,9819414,9837959,9843575,9852145,9872323,9886492,9890970,9988678,10026169,10049786,10075741,10085134,10086340,10092522,10187783,10229072,10347170,10358079,10362357,10428778,10435588,10508618,10523301,10527633,10558875,10567358,10571044,10572067,10595738,10618391,10635327,10648629,10675333,10722725,10731668,10734107,10734310,10777553,10788520,10799548,10805725,10806474,10861448,10888683,10889023,10913131,10918300,10918587,10938113,10953014,10969083,10971656,10980697,10985391,10993906,11094073,11114724,11116146,11161793,11172806,11223155,11226410,11239464,11278868,11279102,11286993,11294897,11349134,11370743,11375397,11408594,11432805,11459228,11467954,11470832,11483589,11500516,11500850,11504770,11506178,11516622,11531336,11533253,11533659,11602604,11687594,11696537,11726515,11751923,11788593,11796728,11814623,11823423,11831486,11839738,11843178,11853560,11875501,11886870,11887937,11894095,11896612,11897506,11912208,11916499,11916981,11935304,11950845,11953893,11956190,11960376,11966576,11968000,11983694,11983899,11992543,11994282,12006493,12006662,12009895,12018405,12023273,12061819,12070153,12093135,12093292,12095417,12099646,12099696,12105206,12127568,12127695,12133497,12134064,12134089,12135609,12147707,12152785,12153558,12161422,12167618,12177062,12180964,12181310,12192610,12198159,12218189,12223352,12234920,12243760,12297049,12297050,12354693,12354760,12381737,12388423,12388817,12397069,12399475,12419588,12429632,12429742,12435727,12444032,12446727,12446789,12454019,12456372,12471035,12477932,12479108,12487410,12488461,12508124,12517767,12517803,12522132,12522133,12527890,12532415,12534349,12534934,12543931,12556561,12560083,12568494,12573287,12577067,12579331,12582944,12586732,12586780,12588871,12589790,12593795,12593796,12601080,12603863,12604776,12606307,12606946,12607604,12614260,12615082,12620237,12631599,12637327,12642595,12643788,12646923,12653106,12654182,12657642,12664617,12672817,12673202,12681285,12683217,12686539,12694196,12704666,12708474,12708492,12719950,12722480,12725245,12733059,12734385,12743604,12746449,12746839,12754251,12754350,12757445,12768436,12771190,12782602,12794748,12795333,12803489,12807903,12814937,12817007,12819035,12824187,12825853,12828935,12829707,12839682,12844146,12853948,12871937,12873986,12878187,12879076,12897150,12900408,12919676,12925580,12930839,12939263,12953068,12953099,12954170,12955084,13679441,13679857,14505571,14506149,14506242,14507652,14512423,14520461,14530278,14551192,14557654,14560030,14568990,14576349,14592989,14607699,14627991,14632199,14647423,14660604,14665621,14670955,14676838,14679214,14681060,14688027,14690686,14701753,14702346,14704150,14711810,14718570,14729599,14734462,14764825,14960328,14963038,14966128,14977086,14977838,14978035,14988406,14996911,15009100,15010475,15026342,15031710,15039424,15042583,15054105,15057284,15063762,15082004,15082764,15100232,15107835,15117950,15118073,15118125,15123705,15134305,15143334,15144186,15159412,15166244,15166495,15182358,15185528,15192046,15205458,15210722,15211117,15212941,15213840,15215236,15219825,15219850,15221011,15225635,15226397,15233293,15245434,15248827,15253134,15253384,15254267,15254682,15256501,15269346,15271882,15282306,15282549,15284024,15284455,15288768,15298855,15300588,15302576,15302935,15305378,15322115,15329413,15335267,15337524,15337756,15340161,15342520,15345710,15358139,15364923,15366372,15383614,15383630,15389569,15389641,15447984,15456872,15465819,15467833,15469987,15469991,15475003,15485674,15485908,15494003,15507625,15519654,15522239,15524283,15540509,15541730,15542601,15545271,15556605,15556944,15557335,15562026,15572377,15574420,15580296,15581623,15588985,15590694,15592685,15618223,15620700,15621729,15623594,15635092,15652339,15652750,15657067,15657358,15665278,15665299,15665312,15668240,156724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25872475,25872741,25873175,25877876,25883211,25885672,25886066,25886585,25886900,25889637,25893361,25903122,25911864,25912735,25915403,25918867,25921002,25921289,25921464,25922063,25922362,25923549,25923550,25925001,25925667,25930120,25931286,25934077,25935365,25936882,25936883,25939061,25953087,25953424,25955689,25959250,25959864,25961746,25964092,25964184,25964481,25966200,25969544,25969993,25971727,25980493,25981168,25991665,25992628,25993617,25996283,26000960,26002322,26006730,26009168,26016774,26021752,26022577,26023239,26026095,26026961,26030178,26034219,26043909,26047463,26047622,26051236,26053020,26055326,26057862,26064952,26066081,26068861,26071255,26075254,26076812,26079101,26079946,26091796,26093903,26094656,26096453,26099724,26101090,26105696,26109002,26114632,26124345,26124364,26125777,26138587,26141217,26143491,26145760,26148607,26150526,26159065,26159916,26161893,26165226,26170125,26171917,26171935,26173590,26174465,26177020,26181014,26181354,26182292,26184032,26186194,26191267,26193216,26209091,26229411,26235264,26239118,26244656,26247735,26248464,26259512,26264748,26268359,26272609,26279457,26280531,26280537,26282175,26299074,26330164,26330166,26335629,26344197,26345124,26350464,26372697,26374070,26381405,26399481,26420346,26440883,26455392,26461062,26475093,26483334,26496610,26505339,26514923,26514924,26551075,26554801,26571401,26581390,26612919,26718225,26753647,26766154,26793845	15		NP_005219.2|MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA,NP_958439.1|MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGS,NP_958440.1|MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGLS,NP_958441.1|MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGPGNESLKAMLFCLFKLSSCNQSNDGSVSHQSGSPAAQESCLGWIPSLLPSEFQLGWGGCSHLHAWPSASVIITASSCH
92	raptor	31543		raptor	4320|CG4320|DmelCG4320|Raptor|dRap|dRaptor|raptor/CG4320	fruit fly	NM_001297995.1,NM_132066.2	NP_001284924.1,NP_572294.2	NC_004354.4	Q9W437	NULL	NULL				Dm.2949	10731132,12537568,12537572,12537573,12537574,15268862,15718470,16110336,16496002,16516475,16627617,16713952,17043309,17086199,17183368,17412918,17462592,17569856,17569867,18084299,18653470,18791638,18854141,19026789,19214224,19216764,19232407,19234471,19543366,19723496,20066047,20585550,20585616,21239477,21267071,21576393,21816278,21847093,22068330,22071194,22102829,22264732,22319582,22493059,22510984,22911822,23144943,23393158,23532117,24389064,24786828,24809668,25007267,25284370,25369313,25393288,25481477,25681415,25866192,25920570,26063572	12		NP_001284924.1|MTSAVRAKSAAAAVGVAVDESSGSSNGSVADQEVASSKEAVLSVLIRKRYEKYVFAPWDDPIILIMEQLEHIEHCRSAALGNQVAIGRDPSQDDSLNDLGKVISNMRQDQSLVPIVKHIEQISDIQASNGQELASLGSLRELIRTIRKEWPRDDSIKLRLKEIQILGMPPARSLCFGERIRDDRCPLSLQTKRHKERIQAMMYERQPWRIRERMKTASVALVLCLNIGVDPPDVVKIQPCSRLECWIDPSSVSPPKAMELIGSNLQMQYERWQPRARYKKCNDPTVDDVKKLCTSLRRNAKGERILFHYNGHGVPKPTANGEIWVFNKTFTQYIPLSIFELITWMSAPSIYVYDCSNAGIIINSFQPYAKQHEEELGKALAAAQQRGGVQQLVGGSGGAANVAANQVQLTNQMVSYKNCIHLAACAANEILPMNAQLPADLFTSCLTTPINIALKWYAMQEKLGMVPRIQSELIDKIPGKVNDRRTMMGELNWIFTAITDTIAWNTLPRELFQRLFRQDLLVASLFRNFLLAERILRSHDCTPVSLPALPPCYRHPMWKAWDLVVDLALQQLPEILDHNAPYRQLPFFEHQLTAFQVWLDSESESRTPPEQLPIVLQVLLSQVHRLRALELLARFLDLGPWAVNLALGVGIFPYVLKLLQSSTRELRPVLVFIWAKILAVDPSCQVDLVKEYKYFLSVLQDTSVSKEHRTLSAFVLSSIVHNFLLGQTSALQGPLLSICLEQLNDGSWLLRQWLAICLGMLWQNFEKARWSGARDLAHEKLYVLLRDSIPEVRAAAVFALGTFISSVTDRSEEQANNIDRIIAITMLETVGEDMSPLVRMELAAALQWMVVLFESQFVAVYLTEHMRGHVSAASFVMCPDPRDLTSSTHSLERHVTIRRGASSSSISNMGGASISSGTGSSSNPLGRSKSGSGSSGGRGAAGAAGGTNSIPFQSIFTKLWLGICNLAQDPFPRVAAIAQEIVEHVRDTALCPIMAAKEATMANASEKCSSLSVSLPPSPNTRVNYLGGGGAPGGAGATAESPPVGAAASGASHWAQKLRLSGSGACMGAGDPQTILQRKLRTSSINDETDSGPGYSRGVAGAGTGLGLPSGPRESTHSARSSGSESNHYLEPGHSLTPIVLTEFIPWAISYFTRPGKERYSSAEGSAEEGRQRFPVDRNSAELRRRRLRFLRNDFVRRHAGRKHQELIDPYGFDVCVWNRKTQFTPSIVKLLPYEPQIAVAYREKVLVYDFQYNSVRTYGAESLGGNFTGYSSGYGSGSGSSSSLNGSTPRKSGAHTSGGGGGGFSAAPFARVSSIEFINAQDMALNLVAHEDGVVRVWQSSPPASSATSEDTPSKARLVTAWTALGQVNQHNHRQRSVASGGSIGKGADASGLSSAAIGSGGIVTAWQQCSQHLVIGGGGCRFIRIWDVERELKLADIPLGRSETCARVLSPYLPNMRSDVILAGCDDGSVRLFDKRCAPQDAGISVYRRHSAPILHASLRANGLVLVSGCTEGRISVADMRGSQSSINPFDVVYEWDAGGDVTAITSHQLEDTVACGNASKIVIYSLDGRQQKVLRTNEGFIGPKIGHPTYLYFHPYKAQLAVGFVDNTVAIYSPTPVL,NP_572294.2|MTSAVRAKSAAAAVGVAVDESSGSSNGSVADQEVASSKEAVLSVLIRKRYEKYVFAPWDDPIILIMEQLEHIEHCRSAALGNQVAIGRDPSQDDSLNDLGKVISNMRQDQSLVPIVKHIEQISDIQASNGQELASLGSLRELIRTIRKEWPRDDSIKLRLKEIQILGMPPARSLCFGERIRDDRCPLSLQTKRHKERIQAMMYERQPWRIRERMKTASVALVLCLNIGVDPPDVVKIQPCSRLECWIDPSSVSPPKAMELIGSNLQMQYERWQPRARYKKCNDPTVDDVKKLCTSLRRNAKGERILFHYNGHGVPKPTANGEIWVFNKTFTQYIPLSIFELITWMSAPSIYVYDCSNAGIIINSFQPYAKQHEEELGKALAAAQQRGGVQQLVGGSGGAANVAANQVQLTNQMVSYKNCIHLAACAANEILPMNAQLPADLFTSCLTTPINIALKWYAMQEKLGMVPRIQSELIDKIPGKVNDRRTMMGELNWIFTAITDTIAWNTLPRELFQRLFRQDLLVASLFRNFLLAERILRSHDCTPVSLPALPPCYRHPMWKAWDLVVDLALQQLPEILDHNAPYRQLPFFEHQLTAFQVWLDSESESRTPPEQLPIVLQVLLSQVHRLRALELLARFLDLGPWAVNLALGVGIFPYVLKLLQSSTRELRPVLVFIWAKILAVDPSCQVDLVKEYKYFLSVLQDTSVSKEHRTLSAFVLSSIVHNFLLGQTSALQGPLLSICLEQLNDGSWLLRQWLAICLGMLWQNFEKARWSGARDLAHEKLYVLLRDSIPEVRAAAVFALGTFISSVTDRSEEQANNIDRIIAITMLETVGEDMSPLVRMELAAALQWMVVLFESQFVAVYLTEHMRGHVSAASFVMCPDPRDLTSSTHSLERHVTIRRGASSSSISNMGGASISSGTGSSSNPLGRSKSGSGSSGGRGAAGAAGGTNSIPFQSIFTKLWLGICNLAQDPFPRVAAIAQEIVEHVRDTALCPIMAAKEATMANASEKCSSLSVSLPPSPNTRVNYLGGGGAPGGAGATAESPPVGAAASGASHWAQKLRLSGSGACMGAGDPQTILQRKLRTSSINDETDSGPGYSRGVAGAGTGLGLPSGPRESTHSARSSGSESNHYLEPGHSLTPIVLTEFIPWAISYFTRPGKERYSSAEGSAEEGRQRFPVDRNSAELRRRRLRFLRNDFVRRHAGRKHQELIDPYGFDVCVWNRKTQFTPSIVKLLPYEPQIAVAYREKVLVYDFQYNSVRTYGAESLGGNFTGYSSGYGSGSGSSSSLNGSTPRKSGAHTSGGGGGGFSAAPFARVSSIEFINAQDMALNLVAHEDGVVRVWQSSPPASSATSEDTPSKARLVTAWTALGQVNQHNHRQRSVASGGSIGKGADASGLSSAAIGSGGIVTAWQQCSQHLVIGGGGCRFIRIWDVERELKLADIPLGRSETCARVLSPYLPNMRSDVILAGCDDGSVRLFDKRCAPQDAGISVYRRHSAPILHASLRANGLVLVSGCTEGRISVADMRGSQSSINPFDVVYEWDAGGDVTAITSHQLEDTVACGNASKIVIYSLDGRQQKVLRTNEGFIGPKIGHPTYLYFHPYKAQLAVGFVDNTVAIYSPTPVL
93	RagA-B	41071		RagA-B	CG11968|DmelCG11968|Gtr1|Rag|RagA|dRagA|dRagB	fruit fly	NM_141593.4	NP_649850.1	NT_033777.3	Q9VHJ4	NULL	NULL				Dm.1110	10731132,12537568,12537572,12537573,12537574,14605208,16110336,17569856,17569867,17660546,18497260,18604198,20457147,20457610,21267071,21816278,22863314,24393626,24529380,26063572	12		NP_649850.1|MKKKVLLMGKSGSGKTSMRSIIFANYIARDTTRLGATIDVEHSHVRFLGNLVLNLWDCGGQEGFMKQYFAQQRDNIFRNVEVLIYVFDVESQEIERDIHYYQSCLEALLQNSPEAKIFCLVHKMDLVPEGLRESVFTERMEDLIKLSKPGNVTCFRTSIWDETLYKAWSSIVTMLIPNVAALENSVTHFGNVIEADEVLLFEKATFLVISHCQSKKNRDSHRFEKVSNIIKQFKLSCSKLGAKFQSMEVRNSAFAAFIDTFTSNTYVMVVMSDPTLPSEATLVNIRNARKYFEELENPSNSAINHHGQRYH
94	RagC-D	35793		RagC-D	CG8707|DmelCG8707|Gtr2|RagC|dRagC	fruit fly	NM_136517.3	NP_610361.1	NT_033778.4	Q7K519	NULL	NULL				Dm.524	10731132,12537568,12537572,12537573,12537574,14605208,15056610,16110336,17569856,17569867,18245838,18497260,18604198,20381137,20457147,21267071,22053050,22980980,24529380	12		NP_610361.1|MSYDDDDYPADTFPKDFGYRAYNQDGLELEPNATGSSETKPRILLMGMRRSGKSSIQKVVFHKMSPNETLFLESTSKIVKDDINNSSFVQFQIWDFPGQIDFFEPTFDSDMIFGGCGALVFVIDAKDDYNEALTKFKNTVLQAYKVNKRIKFEVFIHKVDGISDDSKMESQRDIHQRSSDDLNEAGLDQIHLSFHLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFIPNSGIEKAFLFDVVSKIYIATDSSPVDMQTYELCCDMIDVVIDLSSIYSSEETAFDSGSSSLIKLNNNTILYLREVNKFLALVCILREENFNRQGVIDYNFICFRDAISEVFELRLKRQKQLENNDQDDDDLVDEQTLIRHGHDAGGISRAQPIN
95	Rab7	42841		Rab7	AAF56218|CG5915|DRAB7|DRab7|Dm Rab7|DmRab7|DmelCG5915|Drab7|O76742|RAB7|Rab-7|Rab-r7|dRab7|drab7|rab7	fruit fly	NM_001260347.1,NM_001260348.2,NM_079748.4	NP_001247276.1,NP_001247277.1,NP_524472.1	NT_033777.3	O76742	NULL	NULL				Dm.1701	9074639,9832531,10731132,11104523,11136982,11404335,11697911,11867535,12050111,12427870,12431369,12537568,12537572,12537573,12537574,12593804,12612640,12730121,12743107,12756167,12857788,14523402,14536058,14579253,14605208,14757636,15051737,15102702,15110713,15261673,15367757,15496440,15572139,15620650,15728675,15944190,16041758,16103123,16110336,16113648,16137758,16139221,16155582,16258546,16354714,16530179,16606693,16652170,16713958,16785324,16837550,16862146,16950109,16979555,17006545,17084357,17084358,17151602,17284519,17304216,17329360,17409086,17569856,17569867,17681133,17855388,17919535,18057029,18067683,18272590,18287038,18331716,18335037,18434417,18434418,18498733,18504302,18804371,19000840,19001129,19064670,19064709,19158398,19176804,19214218,19317464,19427848,19506041,19557185,19707569,19736327,19758563,19798413,19906846,19995935,20015953,20110316,20111007,20194640,20226663,20368415,20421416,20451383,20482700,20495530,20504956,20513768,20534670,20551180,20577216,20696708,20702701,20966964,21068057,21149700,21151882,21282466,21316589,21340027,21347281,21458671,21490061,21490149,21533196,21535339,21562262,21571226,21610029,21658948,21710435,21878499,22000105,22036573,22160599,22171073,22190636,22194648,22234859,22253573,22270918,22348149,22389401,22389409,22391037,22542187,22567011,22648168,22736244,22778279,22791894,22794106,22814602,22825871,22844416,22863314,22934826,23178945,23226104,23250212,23292348,23319140,23322046,23335205,23395371,23418349,23492732,23523245,23562806,23591813,23658195,23665457,23676709,23696892,23765091,23771030,23812537,24104056,24114784,24119134,24239514,24244405,24327558,24356450,24401369,24412417,24521780,24553921,24574010,24743267,24781186,24803650,24823375,24855951,24971745,25154396,25220057,25365996,25422373,25617722,25639794,25804739,25942626,25959678	12		NP_001247276.1|MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC,NP_001247277.1|MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC,NP_524472.1|MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC
96	RAF1	5894		RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	human	NM_002880.3,XM_005265355.1,XM_005265357.1,XM_005265358.3,XM_005265359.3,XM_005265360.1,XM_011533974.1,XM_011533975.1	NP_002871.1,XP_005265412.1,XP_005265414.1,XP_005265415.1,XP_005265416.1,XP_005265417.1,XP_011532276.1,XP_011532277.1	NC_000003.12,NC_018914.2,NG_007467.1,NT_022517.19,NW_004929309.1	A0A0S2Z4L5,B4E0X2,L7RRS6,P04049	Cytoplasm.  Cell membrane.  Mitochondrion. Nucleus.	NULL				Hs.159130	1611909,1612588,1639773,1846778,2475255,2955285,2993863,3003687,3616625,7477354,7479742,7517401,7523381,7559537,7628630,7644510,7730360,7731720,7744247,7760835,7766599,7782277,7791872,7862125,7882972,7935795,7939632,7969158,8035810,8063729,8084603,8085158,8125298,8157000,8307946,8321321,8332187,8332195,8349614,8349631,8393135,8394352,8408024,8530446,8601312,8621729,8628317,8663231,8670882,8692945,8702721,8710867,8753867,8756332,8816460,8876196,8887682,8889548,8900182,8910675,8911690,8929531,8929532,8939988,8962087,9001246,9069260,9069267,9091312,9099670,9115221,9144171,9150145,9153224,9154803,9230211,9234708,9261098,9311917,9315742,9446616,9488663,9523700,9553107,9624170,9632690,9658081,9671314,9689060,9710607,9765203,9808624,9819434,9823899,9867809,10064593,10205168,10329666,10369681,10373531,10433554,10454553,10486249,10497893,10498616,10523633,10523642,10531364,10557073,10576742,10585452,10611249,10620507,10644344,10712923,10757792,10783161,10837247,10848612,10869570,10882715,10887173,10922060,10958680,10969079,11005817,11044439,11171046,11226259,11231577,11306563,11325826,11350735,11409918,11427728,11447113,11463741,11520933,11585916,11585923,11604401,11676916,11697890,11733498,11741534,11751906,11756411,11784866,11788587,11853019,11909642,11948406,11969417,11971957,11997508,12010819,12079506,12087097,12127063,12194967,12237340,12244094,12360521,12374792,12379659,12391160,12429936,12477932,12488548,12490852,12551923,12620389,12626521,12663662,12682854,12691824,12717443,12734410,12774123,12843393,12851216,12865432,12925535,12954639,12975377,14597674,14623285,14654780,14654844,14688025,14688280,14724584,14724641,15031288,15035987,15041731,15067053,15075335,15118098,15122343,15150271,15211515,15215316,15302887,15314064,15385642,15451031,15459208,15470083,15485920,15489334,15520859,15591313,15618521,15653554,15657590,15662129,15664191,15666389,15674327,15688026,15705808,15710605,15711535,15752761,15778465,15845549,15849194,15854902,15866172,15899852,15925322,15935327,15936278,15943972,16009725,16029117,16041367,16086581,16093354,16172610,16239230,16266749,16301319,16306228,16330544,16332724,16364241,16364920,16405965,16413928,16465392,16504566,16537381,16537561,16565089,16569214,16575407,16649144,16707572,16803888,16837009,16862215,16883571,16909118,16924233,16964381,17018604,17064357,17081983,17097642,17243098,17277048,17314511,17332776,17353931,17397260,17409432,17428866,17462920,17572489,17603482,17603483,17614099,17635919,17666399,17699868,17724343,17889508,17889669,17979178,17998336,18006502,18022816,18064632,18182859,18241070,18273062,18294816,18316782,18332145,18356164,18465753,18472967,18483265,18556463,18592002,18660489,18708364,18715846,18794803,18952605,19001375,19011619,19020799,19029954,19037990,19047752,19049963,19058874,19063885,19122653,19133693,19197339,19206169,19222999,19298812,19357705,19363522,19380724,19492075,19595761,19608861,19633425,19638574,19638615,19667065,19696784,19710016,19718030,19730683,19737955,19801192,19802003,19805522,19812696,19825990,19881545,19895838,19913121,19917255,19953087,19953625,20039095,20052757,20071468,20086174,20141835,20159553,20178605,20179103,20212043,20230813,20234004,20301303,20301557,20302979,20364151,20372086,20389169,20404846,20489206,20543023,20630999,20679480,20686565,20688353,20802526,20854332,20868603,20947508,21048031,21122381,21139044,21207082,21215703,21336309,21348951,21419342,21457714,21514245,21536655,21577205,21617351,21779496,21808062,21831839,21841781,21871886,21881167,21892329,21917714,21988832,22020327,22081024,22096607,22103831,22110214,22131876,22138288,22169110,22222486,22225925,22262839,22282237,22350907,22389993,22421411,22438909,22447278,22464151,22510884,22556409,22605333,22658674,22678362,22711539,22738312,22752602,22826437,22833462,22886302,22886303,22907845,22922483,22926515,22935974,22939624,23076151,23087049,23105109,23118896,23153539,23157514,23352452,23360980,23383273,23397142,23455922,23517740,23554973,23559827,23602568,23610963,23680146,23737487,23760062,23891004,23923067,24008843,24097068,24108181,24167568,24189400,24223781,24255178,24330068,24371145,24427333,24462205,24486585,24658140,24736947,24746704,24777450,24778252,24863296,24969872,25022756,25027403,25036637,25137548,25155755,25241761,25265753,25355599,25402006,25473895,25476789,25512530,25640309,25674762,25684575,25706034,25713071,25755752,25817574,25852190,26004137,26048984,26100670,26496610,26549023,26578655,26673895,26871637	15		NP_002871.1|MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF,XP_005265412.1|MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF,XP_005265414.1|MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLFSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF,XP_005265415.1|MMANSQILLRQATLSVFSCRTSKEQCKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF,XP_005265416.1|MMANSQILLRQATLSVFSCRTSKEQCKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLFSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF,XP_005265417.1|MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNMPELESFGGKAMWGLKNGLIHN,XP_011532276.1|MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF,XP_011532277.1|MMANSQILLRQATLSVFSCRTSKEQCKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
97	MAP2K1	5604		MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	human	NM_002755.3,XM_011521783.1	NP_002746.1,XP_011520085.1	NC_000015.10,NC_018926.2,NG_008305.1,NT_010194.18,NW_004929398.1	A4QPA9,B4DFY5,Q02750	NULL	NULL				Hs.145442	1281467,7601337,7624324,7731720,7957875,7969158,8131746,8157000,8226933,8388392,8394352,8529659,8621729,8626767,8631303,8900182,8939914,9006895,9069267,9223324,9311917,9325171,9351825,9465908,9553107,9558095,9563949,9564043,9621077,9733512,9765203,9841871,10395327,10402467,10409742,10489373,10509564,10523642,10570282,10644344,10712923,10716983,10748187,10757792,10780709,10799874,10806207,10828601,10848576,10912793,10958680,10969079,10982368,10997882,11044099,11044439,11104681,11134045,11226259,11260070,11266467,11278389,11279118,11352917,11409852,11520933,11535599,11579140,11604401,11684694,11726657,11741534,11741894,11823456,11891225,11940661,11948406,12032872,12063167,12089333,12167619,12370306,12456688,12477932,12482669,12522135,12522145,12531514,12556561,12594221,12609978,12612059,12663662,12682854,12689928,12697810,12775419,12788955,12792650,12807433,12839928,12917419,12975377,14500727,14581471,14656894,14672918,14724641,15020233,15021912,15069060,15090600,15118098,15155804,15231747,15258589,15276183,15284233,15292274,15297310,15299019,15302887,15353548,15485920,15520859,15538402,15543157,15557124,15572374,15615716,15638726,15657353,15657590,15665520,15757891,15866172,15888452,15979847,16086581,16093354,16239230,16291755,16313339,16344560,16439621,16454711,16533805,16728640,16737746,16810323,16820947,16861903,16888650,16957420,17038630,17054908,17101779,17110930,17182854,17192257,17197157,17255949,17260965,17366577,17419998,17461449,17490600,17603482,17667937,17704260,17951252,17979178,17981815,18029348,18042262,18060073,18192500,18329369,18332145,18390968,18413255,18424438,18434598,18533112,18556463,18569454,18593598,18617556,18632602,18660489,19001375,19014680,19056740,19058874,19133693,19153083,19156172,19164283,19197339,19206169,19261809,19322201,19342664,19411838,19447520,19453261,19500021,19565474,19567590,19625741,19681119,19802003,19816936,19835659,19858308,19953087,20007706,20019835,20056645,20172001,20179161,20212043,20299489,20301303,20301365,20301557,20302979,20354455,20404718,20433920,20512084,20610816,20676060,20679487,20885957,20926789,20936779,20956560,21131601,21179471,21336309,21383288,21447798,21458501,21567396,21621846,21675959,21690289,21705440,21707777,21713404,21835307,21965271,22020285,22037177,22052387,22065579,22180573,22188669,22197931,22241220,22298595,22327936,22357202,22495818,22546605,22572157,22588879,22707717,22752157,22773810,22791812,22805291,22805292,22833572,22902540,22935974,22946047,22946697,23001481,23157514,23225884,23237773,23241949,23360980,23376485,23383273,23423222,23524336,23555914,23626836,23684925,23698055,23698777,23727904,23746211,23852369,23923067,24011934,24091658,24104479,24114843,24132923,24211253,24241536,24255178,24338975,24418364,24419498,24445144,24501087,24623782,24639526,24681949,24704364,24709918,24746704,24909280,24982505,25155755,25164676,25188412,25194980,25202140,25351745,25370473,25408231,25416956,25425646,25463315,25534823,25541062,25600339,25710724,25713071,25899310,25943894,26034353,26186194,26324360,26344197,26496610,26549023,26638075	15		NP_002746.1|MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV,XP_011520085.1|MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
98	MAP2K2	5605		MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	human	NM_030662.3,XM_006722799.2,XM_011528133.1	NP_109587.1,XP_006722862.1,XP_011526435.1	NC_000019.10,NC_018930.2,NG_007996.1,NT_011295.12,NW_004929412.1	B3KS97,P36507	Cytoplasm. Membrane.	NULL				Hs.465627	7566098,7687743,7839144,8157000,8226933,8388392,8393135,8529659,8626767,8668348,8702863,9006895,9069267,9159118,9223324,9325171,9427625,9558095,9563949,9621077,9671314,9733512,9781012,9808624,9915804,10224087,10409742,10489373,10509564,10712923,10780709,10799874,10828601,10862698,10982368,11044099,11104681,11134045,11260070,11409852,11520933,11579140,11726657,11823456,11909642,12032872,12063167,12089333,12167619,12477932,12482669,12505790,12531514,12582162,12612059,12775419,12788955,12792650,12839928,14499342,14517288,14656894,14672918,14702039,14724641,15071496,15118098,15276183,15284233,15292274,15302935,15489334,15543157,15638726,15979847,16103188,16239230,16332685,16364241,16439621,16454711,16533805,16651638,16957420,16964243,17038630,17081983,17101779,17192257,17366577,17380122,17419998,17461449,17603482,17643375,17704260,17979178,17981815,18042262,18060073,18390968,18413255,18424438,18569454,18617556,18624398,19014680,19058874,19156172,19164283,19206169,19447520,19453261,19496172,19500021,19565474,19681119,19816936,19858308,19884766,20172001,20301365,20302979,20358587,20404718,20467437,20837746,20885957,20936779,21178588,21365009,21445343,21447798,21458501,21509657,21525035,21615688,21675959,21969554,21988832,22052387,22185284,22197931,22298595,22805291,22805292,22833572,22895183,22902540,22935974,22946697,22990118,23237773,23379592,23423222,23555914,23626836,23684925,24011934,24255178,24311457,24501087,24639526,24704364,24746704,24797263,25218145,25416956,25425646,25463315,25487361,25600339,25852190,26078274,26186194,26344197,26549023,26673895	15		NP_109587.1|MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV,XP_006722862.1|MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV,XP_011526435.1|MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
99	RGS19	10287		RGS19	GAIP|RGSGAIP	human	NM_001039467.1,NM_005873.2,XM_005260182.2,XM_005260183.1,XM_011528484.1,XM_011528485.1,XM_011528486.1	NP_001034556.1,NP_005864.1,XP_005260239.1,XP_005260240.1,XP_011526786.1,XP_011526787.1,XP_011526788.1	NC_000020.11,NC_018931.2,NT_011362.11,NW_004929419.1	B4DP94,P49795	Membrane.	NULL				Hs.422336	8524874,8986788,9305927,9571244,9748280,9770488,10359779,10364213,10452897,10760272,10760275,10906137,10993892,11090272,11251075,11780052,11829488,11956658,12477932,12507475,12826607,14617818,15356268,15489334,15761153,16293724,18360038,19294699,20468064,21705135,21900206,22045062,23416464,23799031,24793302,26116529,26496610	15		NP_001034556.1|MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA,NP_005864.1|MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA,XP_005260239.1|MSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA,XP_005260240.1|MSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA,XP_011526786.1|MGVSRNLQWGPHLGPSLGGGARSCCSSLLNDPGPPPSPAITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA,XP_011526787.1|MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA,XP_011526788.1|MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
100	eIF-2alpha	32617	Eukaryotic translation initiation factor 2 subunit 1	eIF-2alpha	CG9946|DmelCG9946|EIF-2alpha|Eif2alpha|IF2A_DROME|M(1)14C|M(1)19-153|M(1)8e3-10|deIF2alpha|eIF-2|eIF-2 a|eIF-2 alpha|eIF-2alphaeIF-2alpha|eIF2 alpha|eIF2-alpha|eIF2a|eIF2alpha|eiF-2alpha|elF2alpha|l(1	fruit fly	NM_001298400.1,NM_132902.4	NP_001285329.1,NP_573130.1	NC_004354.4	P41374,X2JFR6	NULL	NULL			eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This preinitiation complex mediates ribosomal recognition of a start codon during the scanning process of the leader region.	Dm.3157	1908463,7862085,7893711,8026331,8144032,8244005,8878687,8948593,9139706,9495316,10731132,10908586,11060303,12537568,12537572,12537573,12537574,12605680,12865422,14525933,14605208,15221030,16110336,17151602,17387279,17392269,17412918,17569856,17569867,17927810,18403407,18433294,18723887,19101615,19661161,19889774,20036725,20858900,21239477,21509536,21890737,21954288,22219196,22445104,22500638,22539005,22817988,22884528,23336078,23408971,23583758,23665227,23749869,23944235,23950728,24020503,24058701,24092876,24336168,24347626,24444805,24485457,24550463,25715730	12		NP_001285329.1|MALTSRFYNERYPEIEDVVMVNVLSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLIRVGKTEPVVVIRVDKEKGYIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILGFEGNEKLEDLYQKTAWHFEKKYNNKTVAYDIFKQSVTDPTVFDECNLEPETKEVLLSNIKRKLVSPTVKIRADIECSCYGYEGIDAVKASLTKGLELSTEELPIRINLIAPPLYVMTTSTTKKTDGLKALEVAIEHIRAKTSEYDGEFKVIMAPKLVTAIDEADLARRLERAEAENAQVAGDDDEEDGADQEGMQFDPEKEFNHKGSGAGRANEEDEEEEED,NP_573130.1|MALTSRFYNERYPEIEDVVMVNVLSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLIRVGKTEPVVVIRVDKEKGYIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILGFEGNEKLEDLYQKTAWHFEKKYNNKTVAYDIFKQSVTDPTVFDECNLEPETKEVLLSNIKRKLVSPTVKIRADIECSCYGYEGIDAVKASLTKGLELSTEELPIRINLIAPPLYVMTTSTTKKTDGLKALEVAIEHIRAKTSEYDGEFKVIMAPKLVTAIDEADLARRLERAEAENAQVAGDDDEEDGADQEGMQFDPEKEFNHKGSGAGRANEEDEEEEED
101	Gcn2	43709		Gcn2	CG1609|DGCN2|DmelCG1609|EIF2|GCN2|Gcn-2|dGCN2	fruit fly	NM_001276212.1,NM_001276213.1,NM_057882.4	NP_001263141.1,NP_001263142.1,NP_477230.1	NT_033777.3	A0A0B4KHX7,Q9V9X8	NULL	NULL				Dm.2985	9139706,9649537,10731132,10775272,10908587,11157786,12537568,12537572,12537573,12537574,12605680,14605208,15616552,16110336,17569856,17569867,18981222,19661161,19917724,21954288,22817988,23284702,23418347,23748611,24381562,24485457,24658702,24801064,24937262,25153327,25239948,25284370	12		NP_001263141.1|MADEKAKESFRERQAQELEVIKSIFGCDVEDLRPQANPSLWKPTDIRIQLTPLRDSSNGLETYVCTKLHVTCPSKYPKLPPKISLEESKGMSDQLLEALRNQLQAQSQELRGEVMIYELAQTVQAFLLEHNKPPKGSFYDQMLQDKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFKTEAKRRGEPRRSMSESNPRHPSSSESSENSSPYYRGHIYPSKCLDHRNTETLYFHKMGRQIQRGCCVGHSQRGCIAYTGIDMHCGQLLYITEWNIKYSQLEQPCIGGGKCHWSSESKCMGSHRVDEVMASIEKQVSSLSQLQHKNLVSYECVLCIKRKEGLLVYLVQDFLLGTSVFSISSSLGWCMDGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTGNVRVSDFSLVPNLLELLSGAGQSSSCGDLPALGALVESLMPTNSYEMRDFVDKCNSDRTLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTVQRTGSAMPYQIPTLALSQSRLRTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVRYFNSWIESVDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDEEDSSSSMWNGYIPNMEDSDSDGIEFVDSNGKVAVYDDEEQEDSTRGKTNSPKPLMQVMYIQMEFCEKCTLRTAIDDNLFNDTDRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPVNQITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDTSMERAQTIMALRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPPAQLEANELQEMLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAIIIDDIVSLNPVIEFVKAKVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGCVVVLPCDLRTQFARHVTMNSVNLIRRYCVDRVYREERVFNFHPKQSYDCSFDIIAPTTGSHLVDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDFIESRISRFQFHSSITGIMEKSRTSAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKGEAASLARGALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPNRSGHPSVLAIGERYDSMLHEFQKQAQKFNPAMPARGVLSGAGLTFSLDKLVAAVGVEYAKDCRAIDVGICVCGTRPPLKDVTYIMRLLWSVGIRCGIVEAASELGDEAQDLARLGALHVILVAENGSLRVRSFERERFQERHLTRTELVEFIQKMLRSDGLNGTTVDNFSQLSALGSGDNRSSGGKERERGENGLSTSASNATIKNNYSQLPNLQVTFLTHDKPTANYKRRLENQVAQQMSSTLSQFLKKETFVVLVVELPPAVVNAIVGAINPREIRKRETEPEINYVIERFSKYKRYISEINEEVVDYLSDAKTPIVALYSISDSYYRVII,NP_001263142.1|MADEKAKESFRERQAQELEVIKSIFGCDVEDLRPQANPSLWKPTDIRIQLTPLRDSSNGLETYVCTKLHVTCPSKYPKLPPKISLEESKGMSDQLLEALRNQLQAQSQELRGEVMIYELAQTVQAFLLEHNKPPKGSFYDQMLQDKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFKTEAKRRGEPRRSMSESNPRHPSSSESSENSSPYYRGHIYPSKCLDHRNTETLYFHKMGRQIQRGCCVGEGHSQRGCIAYTGIDMHCGQLLYITEWNIKYSQLEQPCIGGGKCHWSSESKCMGSHRVDEVMASIEKQVSSLSQLQHKNLVSYECVLCIKRKEGLLVYLVQDFLLGTSVFSISSSLGWCMDGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTGNVRVSDFSLVPNLLELLSGAGQSSSCGDLPALGALVESLMPTNSYEMRDFVDKCNSDRTLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTVQRTGSAMPYQIPTLALSQSRLRTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVRYFNSWIESVDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDEEDSSSSMWNGYIPNMEDSDSDGIEFVDSNGKVAVYDDEEQEDSTRGKTNSPKPLMQVMYIQMEFCEKCTLRTAIDDNLFNDTDRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPVNQITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDTSMERAQTIMALRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPPAQLEANELQEMLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAIIIDDIVSLNPVIEFVKAKVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGCVVVLPCDLRTQFARHVTMNSVNLIRRYCVDRVYREERVFNFHPKQSYDCSFDIIAPTTGSHLVDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDFIESRISRFQFHSSITGIMEKSRTSAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKGEAASLARGALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPNRSGHPSVLAIGERYDSMLHEFQKQAQKFNPAMPARGVLSGAGLTFSLDKLVAAVGVEYAKDCRAIDVGICVCGTRPPLKDVTYIMRLLWSVGIRCGIVEAASELGDEAQDLARLGALHVILVAENGSLRVRSFERERFQERHLTRTELVEFIQKMLRSDGLNGTTVDNFSQLSALGSGDNRSSGGKERERGENGLSTSASNATIKNNYSQLPNLQVTFLTHDKPTANYKRRLENQVAQQMSSTLSQFLKKETFVVLVVELPPAVVNAIVGAINPREIRKRETEPEINYVIERFSKYKRYISEINEEVVDYLSDAKTPIVALYSISDSYYRVII,NP_477230.1|MADEKAKESFRERQAQELEVIKSIFGCDVEDLRPQANPSLWKPTDIRIQLTPLRDSSNGLETYVCTKLHVTCPSKYPKLPPKISLEESKGMSDQLLEALRNQLQAQSQELRGEVMIYELAQTVQAFLLEHNKPPKGSFYDQMLQDKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFKTEAKRRGEPRRSMSESNPRHPSSSESSENSSPYYRGHIYPSKCLDHRNTETLYFHKMGRQIQRGCCVGHSQRGCIAYTGIDMHCGQLLYITEWNIKYSQLEQPCIGGGKCHWSSESKCMGSHRVDEVMASIEKQVSSLSQLQHKNLVSYECVLCIKRKEGLLVYLVQDFLLGTSVFSISSSLGWCMDGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTGNVRVSDFSLVPNLLELLSGAGQSSSCGDLPALGALVESLMPTNSYEMRDFVDKCNSDRTLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTVQRTGSAMPYQIPTLALSQSRLRTEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVRYFNSWIESVDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDEEDSSSSMWNGYIPNMEDSDSDGIEFVDSNGKVAVYDDEEQEDSTRGKTNSPKPLMQVMYIQMEFCEKCTLRTAIDDNLFNDTDRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPVNQITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDTSMERAQTIMALRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPPAQLEANELQEMLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAIIIDDIVSLNPVIEFVKAKVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGCVVVLPCDLRTQFARHVTMNSVNLIRRYCVDRVYREERVFNFHPKQSYDCSFDIIAPTTGSHLVDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDFIESRISRFQFHSSITGIMEKSRTSAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKGEAASLARGALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPNRSGHPSVLAIGERYDSMLHEFQKQAQKFNPAMPARGVLSGAGLTFSLDKLVAAVGVEYAKDCRAIDVGICVCGTRPPLKDVTYIMRLLWSVGIRCGIVEAASELGDEAQDLARLGALHVILVAENGSLRVRSFERERFQERHLTRTELVEFIQKMLRSDGLNGTTVDNFSQLSALGSGDNRSSGGKERERGENGLSTSASNATIKNNYSQLPNLQVTFLTHDKPTANYKRRLENQVAQQMSSTLSQFLKKETFVVLVVELPPAVVNAIVGAINPREIRKRETEPEINYVIERFSKYKRYISEINEEVVDYLSDAKTPIVALYSISDSYYRVII
101	GCN2	851877	eIF-2-alpha kinase GCN2 {ECO:0000250|UniProtKB:Q9HGN1}		AAS1|AAS102|NDR2	baker's yeast	NM_001180591.3	NP_010569.3	NC_001136.10	P15442	Cytoplasm.	NULL			(orthologuous-specific) Binds to aminoacylated tRNA(Phe) less tightly than to deacylated tRNA(Phe) (PubMed:10983975). Binds to double-stranded RNA (PubMed:9430731). {ECO:0000269|PubMed:10983975, ECO:0000269|PubMed:9430731}.		1333044,1739968,2038314,2188100,2668117,3537709,3540603,6351059,6387704,7565788,7623840,7934812,8035796,8102207,8164676,8200534,8798780,8849441,8887689,9032257,9169867,9539420,9566889,10048025,10567567,10713174,10775272,10801780,11101534,11350982,11408481,11805826,11805837,12628929,14993275,15314660,15485912,15633294,15879519,15964839,16429126,16554755,16990799,17202131,17704055,17890903,17923092,18417611,19114556,19176519,19269370,19387492,19448108,19546227,19840948,20093466,20404097,20430885,20485439,20489023,20684782,20805354,21126371,21127252,21239490,21459853,21460040,21552543,21849502,21919885,22002225,22039512,22087310,22245679,22282571,22326914,22404850,22888004,23712011,24244480,24391917,24719324,24811037,25437641,25695491,26493364,26673895	28		NP_010569.3|MSLSHLTLDQYYEIQCNELEAIRSIYMDDFTDLTKRKSSWDKQPQIIFEITLRSVDKEPVESSITLHFAMTPMYPYTAPEIEFKNVQNVMDSQLQMLKSEFKKIHNTSRGQEIIFEITSFTQEKLDEFQNVVNTQSLEDDRLQRIKETKEQLEKEEREKQQETIKKRSDEQRRIDEIVQRELEKRQDDDDDLLFNRTTQLDLQPPSEWVASGEAIVFSKTIKAKLPNNSMFKFKAVVNPKPIKLTSDIFSFSKQFLVKPYIPPESPLADFLMSSEMMENFYYLLSEIELDNSYFNTSNGKKEIANLEKELETVLKAKHDNVNRLFGYTVERMGRNNATFVWKIRLLTEYCNYYPLGDLIQSVGFVNLATARIWMIRLLEGLEAIHKLGIVHKCINLETVILVKDADFGSTIPKLVHSTYGYTVLNMLSRYPNKNGSSVELSPSTWIAPELLKFNNAKPQRLTDIWQLGVLFIQIISGSDIVMNFETPQEFLDSTSMDETLYDLLSKMLNNDPKKRLGTLELLPMKFLRTNIDSTINRFNLVSESVNSNSLELTPGDTITVRGNGGRTLSQSSIRRRSFNVGSRFSSINPATRSRYASDFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRHTEEKLSTILSEVMLLASLNHQYVVRYYAAWLEEDSMDENVFESTDEESDLSESSSDFEENDLLDQSSIFKNRTNHDLDNSNWDFISGSGYPDIVFENSSRDDENEDLDHDTSSTSSSESQDDTDKESKSIQNVPRRRNFVKPMTAVKKKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLPVKHQDEVIKEALKSLSNPSSPWQQQVRESLFNQSYSLTNDILFDNSVPTSTPFANILRSQMTEEVVKIFRKHGGIENNAPPRIFPKAPIYGTQNVYEVLDKGGTVLQLQYDLTYPMARYLSKNPSLISKQYRMQHVYRPPDHSRSSLEPRKFGEIDFDIISKSSSESGFYDAESLKIIDEILTVFPVFEKTNTFFILNHADILESVFNFTNIDKAQRPLVSRMLSQVGFARSFKEVKNELKAQLNISSTALNDLELFDFRLDFEAAKKRLYKLMIDSPHLKKIEDSLSHISKVLSYLKPLEVARNVVISPLSNYNSAFYKGGIMFHAVYDDGSSRNMIAAGGRYDTLISFFARPSGKKSSNTRKAVGFNLAWETIFGIAQNYFKLASGNRIKKRNRFLKDTAVDWKPSRCDVLISSFSNSLLDTIGVTILNTLWKQNIKADMLRDCSSVDDVVTGAQQDGIDWILLIKQQAYPLTNHKRKYKPLKIKKLSTNVDIDLDLDEFLTLYQQETGNKSLINDSLTLGDKADEFKRWDENSSAGSSQEGDIDDVVAGSTNNQKVIYVPNMATRSKKANKREKWVYEDAARNSSNMILHNLSNAPIITVDALRDETLEIISITSLAQKEEWLRKVFGSGNNSTPRSFATSIYNNLSKEAHKGNRWAILYCHKTGKSSVIDLQR
102	ATF4	468	Cyclic AMP-dependent transcription factor ATF-4	ATF4	CREB-2|CREB2|TAXREB67|TXREB	human	NM_001675.4,NM_182810.2	NP_001666.2,NP_877962.1	NC_000022.11,NC_018933.2,NT_011520.13,NW_004929430.1	P18848,Q96AQ3	NULL	NULL			Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes. During ER stress response, activates the transcription of NLRP1, possibly in concert with other factors (PubMed:26086088). {ECO:0000250, ECO:0000269|PubMed:15775988, ECO:0000269|PubMed:16682973, ECO:0000269|PubMed:18940792, ECO:0000269|PubMed:26086088}.	Hs.496487	1371974,1534408,1827203,1847461,2516827,8939898,9190894,9295363,9488481,10419887,10591208,11018027,11025215,11087824,11238952,11274184,11478948,11564156,11960987,12477932,12689582,12743605,12805554,12812986,12860379,12871976,14561767,14623284,14630807,14630918,14685163,14695168,14747470,15277680,15314157,15385533,15461802,15475356,15489334,15677469,15775988,15788408,16169070,16189514,16219772,16343488,16682973,16687408,16751776,17042743,17346882,17347301,17369260,17684156,17707795,17726049,17822787,17872950,17938202,17996332,18052253,18163433,18171674,18189280,18195013,18255255,18276110,18330356,18408768,18451308,18635891,18697751,18940792,19017641,19053519,19061639,19073601,19114033,19164757,19193809,19251251,19417138,19447967,19453261,19509279,19855386,19946894,20022965,20102225,20185790,20211142,20398657,20473272,20514020,20551969,20564243,20592469,20724472,20732869,20873783,20936779,21044953,21087962,21113145,21203563,21244365,21408167,21516116,21683813,21706477,21801305,21832049,21866569,21951999,21966512,21988832,22007000,22013210,22016052,22017875,22050711,22052162,22082360,22233381,22246806,22338651,22363646,22422769,22435535,22485215,22609407,22658674,22691366,22813743,22848420,22915762,22934019,22955275,23001845,23078367,23090478,23128233,23153536,23205607,23241898,23242184,23294542,23339444,23392669,23471465,23661758,23665047,23792164,23891064,23908598,23916134,23975372,24021586,24100623,24308964,24330582,24418603,24681956,24715035,24853302,24874742,24905361,24939851,24952347,25002527,25052841,25078779,25130172,25142020,25171414,25236743,25241761,25332235,25375376,25416956,25449779,25515538,25567807,25621764,25681212,25727012,25795775,25931127,26011642,26030745,26091241,26111340,26125799,26172539,26504039	15		NP_001666.2|MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP,NP_877962.1|MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
103	EIF2AK3	9451		EIF2AK3	PEK|PERK|WRS	human	NM_001313915.1,NM_004836.6,XM_005264649.3,XR_939749.1	NP_001300844.1,NP_004827.4,XP_005264706.1	NC_000002.12,NC_018913.2,NG_016424.1,NT_022184.16,NW_004929300.1	B3KY45,E7ER02,Q68DI6,Q9NZJ5	Endoplasmic reticulum membrane.	NULL				Hs.591589	1677563,8099443,9819435,10026192,10542257,10575235,10677345,10848580,10932183,11555640,11907036,12014989,12086964,12370288,12446770,12446838,12477932,12610133,14517290,15146197,15220213,15234121,15483661,15489334,15650164,16147992,16148948,16288713,16344560,16720581,17229688,17785458,17823375,18063576,18216498,18426796,18451152,18664456,18787411,19009018,19029953,19061639,19586904,19816510,19837917,19913121,19946888,20072656,20103619,20202148,20348950,20371724,20379614,20457808,20463975,20628086,20709135,20800603,20881960,21385877,21419175,21464971,21518408,21648287,21685912,21709020,22013210,22028037,22072062,22169477,22246806,22253692,22354021,22446326,22795130,22813743,22915762,22917505,22934019,22956602,23000344,23103912,23110043,23116876,23160380,23294542,23471998,23585173,23592989,23759358,23830192,24097291,24103755,24114838,24168455,24252572,24457600,24594363,24664756,24705811,24813399,24846185,24874742,25183803,25203443,25226532,25329545,25393282,25429064,25475719,25579883,25609649,25675914,25692299,25761777,25925385,25976933,25996949,26078722,26186194,26268696,26638075,26642955	15		NP_001300844.1|MIIPSLDGALFQWDQDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN,NP_004827.4|MERAISPGLLVRALLLLLLLLGLAARTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDETELRPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGALFQWDQDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN,XP_005264706.1|MEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN
104	ERN1	2081	Endoribonuclease	ERN1	IRE1|IRE1P|IRE1a|hIRE1p	human	NM_001433.3,NM_152461.2	NP_001424.3	NC_000017.11,NC_018928.2,NT_010783.16,NW_004929407.1	O75460	Endoplasmic reticulum membrane.	NULL			Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. {ECO:0000250|UniProtKB:Q9EQY0, ECO:0000269|PubMed:11175748, ECO:0000269|PubMed:12637535, ECO:0000269|PubMed:9637683}.	Hs.133982,Hs.700027,Hs.744953	9637683,10587643,10650002,10737800,11175748,11278723,11779464,11779465,11850408,11897784,12050113,12446770,12477932,12637535,12843613,14702039,15063770,15234121,16107700,16344560,16645094,16680093,17585877,17638880,17951406,17991856,18065414,18242182,18369366,18840095,19135427,19328063,19622636,19913121,20007910,20013084,20103773,20379614,20447464,20625543,20628086,20702765,20798350,20819778,20965234,21118962,21317875,21385877,21482118,21525936,21680894,21954231,22013210,22194594,22199355,22219383,22314839,22315414,22419015,22446326,22718352,22787145,22917505,23000344,23001845,23041190,23042294,23103912,23110043,23363253,23378536,23529610,23575540,23598528,23602568,23684307,23748775,23752693,23830192,23880584,23942232,23950715,24121653,24177270,24240056,24330607,24497642,24524643,24565834,24664756,24743743,24810055,24936061,24951540,24970676,25142592,25170079,25225294,25226532,25241761,25437541,25475719,25476903,25495526,25516437,25675914,25692299,25742138,25797626,25816608,25870107,25901709,25968568,25976933,25993558,26056941,26093676,26125799,26173697,26254280,26255341,26306048,26438213,26469762,27025058,27025059	15		NP_001424.3|MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFHEPPEPQPPVTPDAL
105	TRAF2	7186		TRAF2	MGC:45012|TRAP|TRAP3	human	NM_021138.3,XM_005266099.3,XM_011518973.1,XM_011518974.1,XM_011518975.1,XM_011518976.1,XM_011518977.1,XM_011518978.1	NP_066961.2,XP_005266156.1,XP_011517275.1,XP_011517276.1,XP_011517277.1,XP_011517278.1,XP_011517279.1,XP_011517280.1	NC_000009.12,NC_018920.2,NT_008470.20,NW_004929369.1	A0A024R8H5,Q12933	Cytoplasm.	NULL				Hs.522506	7639698,7758105,8069916,8125298,8548810,8565075,8612133,8627180,8643514,8662842,8692885,8702708,8710854,8875942,8943045,8985011,8999898,9020361,9104814,9151858,9153189,9162022,9168896,9208847,9244310,9275204,9353251,9384571,9418902,9461607,9464265,9488716,9500555,9582383,9607925,9685412,9692890,9705938,9712898,9718306,9733516,9774460,9774977,9794406,9827693,9852070,9990007,10025951,10037686,10075662,10206649,10339433,10346818,10352240,10411888,10477597,10490605,10514511,10521462,10523862,10544141,10581243,10617615,10650002,10753917,10759890,10764746,10809768,10837247,10880535,10882101,10892748,10903733,10911999,10980203,10990461,11035039,11057907,11064452,11112773,11181075,11278268,11278723,11279055,11340079,11359906,11374864,11384837,11435475,11466612,11479302,11562359,11607847,11728344,11777919,11784851,11798190,11804591,11805080,11821416,11882293,11907088,11907583,11932422,11971184,12005438,12136106,12169272,12220533,12296995,12411322,12411493,12477932,12529173,12547194,12571250,12591926,12637493,12796506,12842894,12843613,12867425,12887920,12917691,14517219,14557256,14585990,14633987,14644197,14685163,14702039,14741690,14743216,14982987,15084608,15121867,15125833,15208311,15258597,15265700,15308666,15310755,15327770,15383523,15485634,15485837,15489334,15670770,15670977,15696169,15707590,15708970,15743837,15861135,15941918,15944293,16009713,16153868,16189514,16214042,16227629,16260598,16263936,16282325,16291755,16304992,16311516,16341674,16378096,16446357,16603398,16611992,16636664,16713569,16876162,16891304,16936264,17015619,17314283,17353931,17379600,17384642,17389591,17544371,17599408,17626074,17724081,18022363,18024283,18029348,18069092,18221368,18230756,18271526,18292192,18312353,18362156,18362886,18671942,18776134,18787502,18818748,18827186,18950704,18981220,18990758,19019335,19150425,19151112,19234489,19243308,19287455,19336370,19380743,19453261,19506082,19527514,19573080,19584093,19586614,19667091,19690440,19773279,19795416,19810754,19815541,19937093,20005846,20047764,20056178,20064526,20133937,20138174,20184394,20237496,20333651,20348096,20368287,20385093,20447407,20448643,20449947,20562859,20568250,20577214,20585848,20614026,20628086,20676093,20732415,20856938,20949042,21041452,21041727,21071692,21078624,21119000,21229359,21266470,21282461,21282507,21289304,21325409,21331077,21421854,21516116,21525013,21620750,21653699,21782231,21793045,21810480,21813773,21822258,21864338,21886773,21903422,21921033,21988832,22013210,22029577,22078441,22167321,22170762,22179575,22184250,22195745,22212761,22271254,22343716,22525270,22585859,22685297,22711886,22792062,22847298,23000344,23007157,23051914,23085658,23088713,23142077,23160117,23188828,23301098,23357418,23381138,23405219,23414308,23453969,23524849,23543740,23595117,23608757,23624947,23638224,23690480,23743189,23754945,23772036,23774506,23775076,23885119,23890813,23918987,23972990,24008839,24276241,24362534,24429366,24434549,24457600,24457959,24457966,24464131,24552808,24586810,24633224,24658140,24722188,24726327,24735611,24841215,24912918,24980434,25029497,25051892,25056949,25134449,25225294,25241761,25246529,25260751,25299769,25402006,25416956,25636800,25681446,25715336,25716317,25795708,25797626,25852190,25911380,25963095,25996949,26038599,26186194,26212014,26221961,26299341,26389662,26390021,26521044	15		NP_066961.2|MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_005266156.1|MGLEGLQGSLKLCDSASLSLDRRALFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_011517275.1|MQTSEKEASSRCEQVDCGYLRKEPTWESPELRHGQSESPLSSQQTRALFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_011517276.1|MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_011517277.1|MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_011517278.1|MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_011517279.1|MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL,XP_011517280.1|MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
106	CHUK	1147	Inhibitor of nuclear factor kappa-B kinase subunit alpha	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	human	NM_001278.4,NM_001320928.1,XM_011539196.1,XM_011539197.1,XM_011539198.1,XR_945589.1,XR_945590.1	NP_001269.3,NP_001307857.1,XP_011537498.1,XP_011537499.1,XP_011537500.1	NC_000010.11,NC_018921.2,NG_028023.1,NT_030059.14,NW_004929376.1	O15111	Cytoplasm. Nucleus.	NULL			Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Negatively regulates the pathway by phosphorylating the scaffold protein TAXBP1 and thus promoting the assembly of the A20/TNFAIP3 ubiquitin-editing complex (composed of A20/TNFAIP3, TAX1BP1, and the E3 ligases ITCH and RNF11). Therefore, CHUK plays a key role in the negative feedback of NF-kappa-B canonical signaling to limit inflammatory gene activation. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa- B RelB-p52 complexes. In turn, these complexes regulate genes encoding molecules involved in B-cell survival and lymphoid organogenesis. Participates also in the negative feedback of the non-canonical NF-kappa-B signaling pathway by phosphorylating and destabilizing MAP3K14/NIK. Within the nucleus, phosphorylates CREBBP and consequently increases both its transcriptional and histone acetyltransferase activities. Modulates chromatin accessibility at NF-kappa-B-responsive promoters by phosphorylating histones H3 at 'Ser-10' that are subsequently acetylated at 'Lys-14' by CREBBP. Additionally, phosphorylates the CREBBP-interacting protein NCOA3. Also phosphorylates FOXO3 and may regulate this pro-apoptotic transcription factor (PubMed:15084260). {ECO:0000269|PubMed:12789342, ECO:0000269|PubMed:15084260, ECO:0000269|PubMed:17434128, ECO:0000269|PubMed:20434986, ECO:0000269|PubMed:20501937, ECO:0000269|PubMed:21765415}.	Hs.198998	7558004,8246997,8777433,9244310,9252186,9346241,9346484,9346485,9409737,9520446,9632806,9689078,9721103,9742107,9744859,9751059,9751060,9813230,9819420,9891086,9914500,10022904,10072079,10094049,10187861,10195894,10469655,10485710,10485711,10521409,10648614,10713178,10723127,10733566,10747982,10755617,10779355,10848576,10848580,10887201,10962033,10968790,10980203,11002417,11042193,11057907,11080499,11095741,11096118,11113112,11136824,11278268,11359906,11485410,11527961,11585904,11594795,11805286,11809792,11815618,11830587,11853669,11864612,11877453,11940602,11959143,11971985,11976329,12048203,12054687,12070292,12093792,12133833,12138192,12190313,12210728,12244103,12351658,12411322,12459277,12477932,12482991,12486103,12504025,12547194,12589056,12612076,12637324,12707358,12709429,12730857,12771929,12789342,12842894,12943667,14499622,14585846,14585847,14585990,14597638,14695475,14743216,14963024,15071597,15084260,15084608,15125834,15140882,15153339,15164054,15184390,15208311,15218148,15226448,15276183,15310755,15383283,15389589,15456791,15469934,15489227,15494311,15590691,15601829,15670770,15677466,15749833,15761153,15782119,15800029,15802604,15808510,15836773,15845455,15856023,16034126,16046471,16051665,16126728,16129692,16177806,16258173,16280329,16286467,16303288,16319058,16344560,16354686,16356855,16365431,16382138,16385451,16393995,16405428,16407216,16497931,16498412,16583354,16611882,16651533,16733051,16840786,16893890,16902410,16938294,17000764,17047224,17053167,17079494,17102620,17138672,17145747,17182689,17237423,17237434,17237443,17244613,17272824,17289033,17317777,17319651,17363905,17363973,17379600,17384642,17434128,17439942,17452332,17452475,17507655,17537731,17540171,17563756,17568778,17597077,17616684,17620599,17630505,17643371,17684021,17693255,17703412,17728323,17785555,17823124,17897950,17914462,17939994,17977820,18003900,18029348,18071880,18074035,18079694,18163512,18180283,18207244,18224289,18266467,18268325,18362886,18443205,18490760,18501560,18512729,18519641,18550535,18560356,18571841,18579519,18593939,18600435,18604171,18625728,18626576,18633439,18688039,18704119,18760861,18782346,18818691,18829575,18922877,18940312,18949366,18952893,18990758,19050262,19074436,19085841,19088076,19104039,19150425,19223558,19258923,19270264,19287455,19421711,19453261,19488402,19573080,19656241,19728335,19773279,19786094,19815509,19838210,19851296,19854138,19875381,19909783,19913121,19948975,19959994,20005846,20026656,20028970,20043910,20051109,20056178,20098747,20100315,20133937,20145131,20149620,20164171,20198315,20200282,20331378,20348096,20351780,20356841,20368414,20378831,20379146,20434986,20448286,20449947,20501937,20503287,20508983,20568250,20614026,20628086,20634891,20671123,20684021,20711193,20817876,20855622,20932476,20940109,20961246,21048031,21056038,21081648,21170261,21191633,21248029,21451574,21455180,21474709,21482671,21571356,21575199,21703539,21724995,21765415,21784860,21795344,21862596,21887257,21903422,21988832,22149351,22156202,22196886,22262057,22384180,22407921,22435562,22474019,22480519,22547678,22605335,22660635,22740410,22748238,22776252,22810585,22848609,22863883,22891964,22939629,22990857,23007157,23027537,23032264,23035900,23041317,23091055,23115237,23131831,23178494,23322406,23343355,23444213,23455325,23477746,23501112,23563314,23597566,23602409,23602568,23636414,23708292,23732909,23774506,23776175,23778976,23872070,23894194,23986494,24075781,24189400,24215713,24270572,24469399,24556686,24618592,24720748,24753359,24874739,24971480,24990947,25036637,25064159,25096806,25187543,25241761,25304104,25482200,25740981,25748427,25852190,25900832,25921289,26060140,26186194,26240016,26496610,26603838,26673895	15		NP_001269.3|MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIEENLNCLGHLSTIIHEANEEQGNSMMNLDWSWLTE,NP_001307857.1|MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVGDFSTNDRRKFELPWPFKHYYS,XP_011537498.1|MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIEENLNCLGHLSTIIHEANEEQGNSMMHFICNKFSCS,XP_011537499.1|MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVGDFSTNDRRKFELPWPFKHYYS,XP_011537500.1|MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVGDFSTNDRRKFELPWPFKHYYS
107	CDKN2A	1029		CDKN2A	ARF|CDK4I|CDKN2|CMM2|INK4|INK4A|MLM|MTS-1|MTS1|P14|P14ARF|P16|P16-INK4A|P16INK4|P16INK4A|P19|P19ARF|TP16	human	NM_000077.4,NM_001195132.1,NM_058195.3,NM_058196.1,NM_058197.4,XM_005251343.1,XM_011517675.1,XM_011517676.1,XM_011517677.1,XM_011517678.1,XM_011517679	NP_000068.1,NP_001182061.1,NP_478102.2,NP_478104.2,XP_005251400.1,XP_011515977.1,XP_011515978.1,XP_011515979.1,XP_011515980.1,XP_011515981.1	NC_000009.12,NC_018920.2,NG_007485.1,NT_008413.19,NW_004929342.1	G3XAG3,K7PML8,P42771,Q8N726	Mitochondrion.	NULL				Hs.512599	7541708,7603984,7604013,7624129,7624155,7647780,7726912,7882351,7970734,7972006,7987387,7987388,8060323,8152487,8153634,8259215,8595405,8622687,8710906,8723678,8755727,8783570,8805225,8910511,9054499,9228064,9328469,9380698,9425228,9482104,9516223,9529248,9529249,9653180,9724636,9751050,9916806,10205165,10208428,10353611,10360174,10445844,10484981,10491434,10556039,10580009,10585280,10651484,10719365,10801444,10822382,10871849,10874641,10891505,10892805,10956390,11008905,11122857,11136714,11156381,11223036,11278317,11297540,11314011,11314038,11382768,11500805,11556834,11642719,11668523,11687599,11692873,11695244,11700040,11705866,11718560,11719461,11720478,11726555,11733969,11739795,11740049,11749694,11758167,11763427,11775544,11792819,11800646,11804283,11807902,11820732,11830494,11836163,11836554,11839577,11839665,11850526,11859122,11859969,11860939,11861400,11869511,11869517,11874489,11883935,11889694,11900540,11908877,11920239,11920642,11943335,11948103,11953887,11956078,11960384,11960918,11992549,12000709,12009890,12016143,12036898,12046062,12060387,12065407,12072536,12072543,12073046,12077343,12082609,12082610,12082630,12082636,12085228,12091906,12099684,12101111,12101670,12107107,12115568,12124774,12127556,12149228,12151395,12152785,12154087,12167711,12168936,12169206,12199782,12200117,12203782,12209876,12228235,12296515,12297306,12357355,12359767,12360404,12360471,12362978,12362979,12368906,12370286,12391839,12406345,12417717,12419160,12420227,12429789,12438273,12446718,12454511,12459643,12459644,12459645,12477932,12482990,12507899,12507935,12514789,12529334,12532425,12549483,12556369,12556559,12565176,12581788,12581892,12582152,12592382,12606707,12610506,12624503,12632489,12632492,12640129,12660818,12665584,12670910,12673200,12684623,12684640,12698196,12702553,12717828,12738733,12738984,12740913,12753296,12759390,12763133,12777976,12783933,12792748,12819388,12824886,12853838,12860972,12875969,12883368,12883667,12911724,12918069,12924439,12924440,12949053,12950144,12963980,14506702,14508519,14519636,14536079,14585357,14586645,14601048,14604992,14612427,14636574,14646619,14657708,14665636,14679123,14717921,14719099,14719109,14719111,14720514,14722037,14729628,14732230,14732922,14735200,14743210,14749371,14966292,14981901,14985402,14991744,15012776,15014024,15014032,15018706,15059516,15065884,15073118,15075790,15083191,15094066,15107860,15112341,15122588,15138269,15140233,15146471,15149599,15150307,15164053,15168247,15195142,15197677,15199070,15205349,15210108,15223748,15232106,15254040,15254707,15257544,15258567,15260847,15286709,15292938,15297411,15297971,15304099,15305154,15305164,15308640,15328914,15336553,15355988,15361825,15361884,15367673,15367885,15370242,15373786,15378017,15381905,15447998,15450420,15455389,15459500,15485902,15489334,15492837,15492852,15492985,15495191,15502810,15523694,15547691,15567177,15569978,15577313,15582998,15608367,15620660,15623583,15649253,15655836,15668906,15672251,15688012,15701851,15701968,15705881,15724013,15729358,15750619,15757201,15775976,15785933,15796965,15800668,15809712,15811326,15813917,15819981,15824172,15824739,15832197,15842853,15856016,15859515,15860862,15876874,15878620,15879498,15888044,15897876,15913553,15915391,15917995,15930346,15937071,15960923,15985168,15989956,15998377,16007099,16100943,16107876,16115911,16117791,16135794,16142358,16161044,16163549,16173922,16184554,16199529,16201750,16203797,16211008,16222700,16234564,16243918,16254068,16254459,16257403,16273250,16288006,16289646,16313047,16314743,16316628,16320052,16350398,16354203,16357845,16374456,16395703,16410719,16412137,16415792,16447252,16449650,16449996,16464125,16481301,16501607,16504234,16508011,16533425,16533530,16537449,16541270,16551852,16572177,16575904,16582619,16582626,16614725,16614947,16616093,16618779,16618910,16619045,16619216,16623784,16627991,16633070,16633071,16646054,16649250,16675157,16679321,16696307,16697958,16699861,16705183,16713577,16723698,16754749,16760301,16765318,16766534,16767161,16778587,16784614,16786135,16791592,16799475,16799478,16802342,16820088,16828922,16855788,16858682,16867217,16888288,16893909,16896043,16897432,16901784,16905682,16909113,16912209,16919029,16924243,16948516,16957780,16988943,16989737,17001621,17008550,17017004,17028578,17035234,17047042,17052587,17060721,17061045,17063143,17072968,17094449,17094467,17106238,17110379,17116689,17117177,17149367,17171691,17195959,17198183,17198188,17198740,17201148,17206475,17216555,17218939,17225865,17233832,17243166,17255954,17274640,17276933,17289033,17292825,17294450,17297463,17326708,17333389,17334400,17340131,17344414,17351341,17351674,17353931,17369842,17373842,17388661,17393105,17409409,17420273,17426254,17428253,17429140,17452980,17459456,17460193,17461444,17463246,17463248,17463249,17466040,17475325,17478679,17478681,17479413,17486064,17486078,17488404,17492760,17493032,17493241,17498885,17505013,17505264,17507663,17512033,17517622,17523078,17533400,17535296,17539963,175434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2,24431303,24436120,24440092,24440286,24449825,24464562,24473065,24485399,24487593,24491138,24495407,24503757,24505435,24509480,24515764,24518594,24522534,24525025,24525695,24529061,24560018,24569073,24572376,24573017,24577117,24588771,24599170,24599991,24606815,24607493,24612037,24623965,24625418,24633888,24642606,24656093,24672805,24673285,24676500,24698966,24710824,24739827,24740700,24742402,24747207,24747969,24760498,24767865,24769896,24778252,24785530,24793773,24798431,24803719,24806561,24811488,24816738,24820457,24837742,24839133,24850170,24855949,24875940,24876098,24878818,24893334,24908414,24913706,24925218,24929480,24930384,24935385,24935963,24937448,24950189,24968695,24969958,24983247,24991542,24999598,25003221,25003838,25012870,25023876,25028366,25029561,25033601,25046224,25053516,25053593,25062258,25064638,25065444,25069600,25072932,25077370,25129146,25138050,25149503,25149524,25155625,25164462,25169493,25181340,25187374,25188353,25205430,25207720,25217637,25222242,25224768,25227142,25236571,25239644,25261804,25264243,25267748,25280564,25289642,25294903,25304494,25308604,25319982,25331947,25337256,25344837,25361631,25370744,25386766,25417611,25432631,25439690,25464386,25465729,25467050,25471335,25480095,25488749,25497382,25499675,25515124,25523612,25541826,25542698,25544647,25544708,25547827,25550505,25550546,25551298,25556463,25558642,25567807,25575976,25576161,25578974,25579180,25592620,25596080,25605180,25616284,25619363,25640309,25640361,25652585,25661481,25667294,25668009,25674264,25675191,25675863,25688737,25691462,25693938,25705251,25711229,25723571,25735349,25744911,25752701,25752754,25765380,25784651,25787093,25798586,25809483,25818616,25835498,25839936,25852058,25853694,25866970,25879218,25885064,25886176,25890228,25891176,25908244,25910412,25921285,25923845,25943250,26017881,26022239,26055329,26057448,26057450,26074259,26104880,26111702,26118188,26125737,26152733,26168478,26171917,26171937,26186194,26187004,26190415,26191206,26191276,26201719,26212014,26230097,26248224,26254363,26255234,26330556,26334876,26335606,26341139,26365380,26371784,26379150,26400483,26416059,26448191,26487755,26496610,26504065,26514741,26527286,26537237,26578773	15		NP_000068.1|MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD,NP_001182061.1|MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA,NP_478102.2|MVRRFLVTLRIRRACGPPRVRVFVVHIPRLTGEWAAPGAPAAVALVLMLLRSQRLGQQPLPRRPGHDDGQRPSGGAAAAPRRGAQLRRPRHSHPTRARRCPGGLPGHAGGAAPGRGAAGRARCLGPSARGPG,NP_478104.2|MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVGRGSAAGAGDGGRLWRTKFAGELESGSASILRKKGRLPGEFSEGVCNHRPPPGDALGAWEAKEEE,XP_005251400.1|MMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD,XP_011515977.1|MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSAGWTNLRISKPNCAWHHLEISRSRLFCTTQLI,XP_011515978.1|MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSVTASIQVPGGEEGDFGSSYS,XP_011515979.1|MGRGRCVGPSLQLRGQEWRCSPLVPKGGAAAAELGPGGGENMVRRFLVTLRIRRACGPPRVRVFVVHIPRLTGEWAAPGAPAAVALVLMLLRSQRLGQQPLPRRPGINQFSGRM,XP_011515980.1|MGRGRCVGPSLQLRGQEWRCSPLVPKGGAAAAELGPGGGENMVRRFLVTLRIRRACGPPRVRVFVVHIPRLTGEWAAPGAPAAVALVLMLLRSQRLGQQPLPRRPETLRIPEA,XP_011515981.1|MMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD
108	CDKN1B	1027	Cyclin-dependent kinase inhibitor 1B	CDKN1B	CDKN4|KIP1|MEN1B|MEN4|P27KIP1	human	NM_004064.4	NP_004055.1	NC_000012.12,NC_018923.2,NG_016341.1,NT_009714.18,NW_004929383.1	P46527,Q6I9V6	NULL	NULL			Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. {ECO:0000269|PubMed:10831586, ECO:0000269|PubMed:12244301, ECO:0000269|PubMed:16782892, ECO:0000269|PubMed:17254966, ECO:0000269|PubMed:19075005}.	Hs.238990	7478582,7882308,7882309,7882310,8012384,8033212,8530100,8560263,8596954,8629023,8637577,8684460,8756624,8891332,8978686,9106657,9192873,9218599,9311993,9380407,9464540,9467944,9472014,9632134,9658399,9660939,9699679,9716181,9716736,9724724,9731735,9811456,9840927,9840943,9858585,9891079,10022926,10098522,10198259,10208428,10323868,10337545,10342870,10361114,10393546,10397455,10514396,10559792,10559916,10585280,10597239,10779628,10828884,10891500,10891505,10908655,10913178,10918569,10944199,10973491,11076863,11278754,11360184,11374878,11420686,11463388,11565034,11800646,11875067,11877274,11877298,11884439,11889117,11908736,11920465,11931757,11940481,11940657,11957145,11967155,12015771,12036888,12036906,12042314,12051866,12051885,12052868,12070150,12082530,12082635,12085261,12086850,12093740,12101669,12119282,12123335,12133429,12133571,12140288,12188931,12202478,12210483,12239454,12244301,12244302,12244303,12351407,12356941,12386815,12401804,12413889,12417722,12429629,12464637,12477932,12482975,12490316,12501191,12507555,12508646,12515730,12527941,12529174,12529328,12529437,12531224,12576455,12579309,12599217,12637327,12642875,12670508,12682919,12684422,12684618,12698196,12700629,12727815,12748192,12771291,12777997,12800980,12809895,12813041,12820381,12824885,12837699,12850001,12860294,12882323,12883474,12904306,12947099,12954644,12963725,12963837,12972555,14517080,14534684,14558671,14573608,14586408,14606065,14612944,14614018,14654548,14666612,14694185,14707456,14707458,14719054,14747563,14760081,14871979,14984940,15014027,15024385,15026335,15034923,15050687,15057270,15060836,15061869,15064717,15075339,15084260,15096506,15133847,15146197,15154004,15161709,15170516,15188025,15199159,15217930,15239677,15271792,15289327,15302935,15314639,15352609,15355997,15358549,15374880,15378017,15457580,15469821,15475071,15480426,15489334,15489336,15492811,15531880,15557281,15579463,15579505,15583032,15592362,15605273,15611642,15619620,15627896,15645120,15647380,15647383,15652359,15652749,15688004,15688030,15695403,15701850,15708847,15710386,15713665,15718252,15722793,15735731,15736055,15743786,15746092,15746103,15777850,15798096,15813917,15833859,15890360,15924242,15936816,15963850,15996662,16006622,16012758,16019539,16022660,16023837,16024059,16035731,16052694,16086840,16097446,16123592,16135812,16169070,16189514,16191374,16194892,16209941,16254341,16273250,16283443,16289477,16300740,16322693,16326706,16344560,16365885,16381901,16391524,16398674,16407831,16425372,16458085,16463785,16465393,16467204,16474380,16480585,16526056,16532026,16537899,16554660,16598766,16636894,16705171,16774918,16780593,16782892,16804901,16835890,16842750,16880511,16939421,16951171,16966613,17008550,17013388,17030811,17053782,17072949,17072952,17123889,17148774,17178856,17188136,17203174,17216128,17237771,17239930,17254966,17254967,17285761,17293600,17303695,17311291,17316413,17319789,17357515,17372254,17404431,17404436,17407140,17409409,17418410,17448572,17464290,17470459,17502456,17519308,17550142,17553787,17554557,17560996,17567920,17581405,17586698,17601350,17611557,17613551,17627278,17651785,17671428,17685465,17692879,17695524,17710155,17721077,17803708,17804714,17851288,17854759,17908995,17914108,17927588,17951406,17974037,17974156,18006823,18027257,18032931,18036045,18037997,18073348,18089324,18095123,18154709,18156402,18174243,18177895,18180298,18181833,18202760,18203777,18222429,18226337,18239684,18246793,18272788,18281517,18281541,18285702,18288099,18301453,18305109,18321488,18327303,18334837,18334933,18346358,18350604,18363870,18385518,18393360,18408738,18415709,18425369,18437054,18459109,18476592,18507837,18514141,18521080,18543099,18568767,18570873,18583941,18593906,18593937,18598941,18604165,18604603,18615582,18644126,18645269,18647205,18663445,18673462,18676680,18691549,18694622,18695910,18708351,18710468,18710949,18756055,18758183,18766473,18769118,18781093,18788572,18794148,18805092,18808421,18818203,18818877,18822693,18823025,18838534,18850315,18855981,18922157,18925698,18953829,18977241,18987662,19010853,19020940,19034576,19038492,19040567,19056892,19064572,19077036,19079342,19082479,19088079,19093261,19096232,19106631,19107213,19112177,19123975,19124506,19139918,19141585,19170105,19170196,19187271,19221487,19236751,19258477,19263441,19266349,19273599,19276255,19281796,19293259,19298520,19304516,19322201,19349901,19351827,19379560,19397698,19424645,19430707,19445020,19451650,19461157,19470470,19473963,19474519,19493606,19522032,19531414,19533041,19536092,19542220,19556892,19557642,19559782,19576211,19584057,19587092,19591933,19594747,19625176,19631451,19636294,19657571,19667240,19686743,19692168,19698214,19723645,19724954,19727727,19730150,19734935,19738611,19777788,19789190,19817957,19819988,19832036,19838216,19843869,19860623,19887899,19889619,19910837,19912438,19913121,19923826,19924135,19938192,19952944,19953484,19959471,20011080,20054616,20059402,20074558,20075119,20108172,20143334,20146005,20160477,20160482,20193371,20360068,20372838,20399237,20448040,20453000,20458559,20492341,20507346,20508912,20530095,20541486,20541671,20546339,20558775,20565904,20608352,20615757,20624000,20626751,20628086,20631637,20647308,20661724,20663873,20668328,20683061,20698225,20713460,20723295,20813693,20818387,20818424,20819778,20824794,20833334,20837141,20851109,20890423,20980721,21045237,21048031,21054888,21062737,21067268,21075101,21115898,21177330,21182779,21216562,21224344,21236467,21237244,21245140,21264218,21278490,21289244,21310472,21338280,21351264,21355095,21371741,21422114,21423214,21423803,21454826,21464733,21478095,21478681,21503567,21508681,21552422,21575583,21575944,21628527,21637966,21715330,21715331,21762277,21780161,21785466,21795702,21813412,21828232,21840777,21841827,21885849,21907315,21981759,21988832,22014979,22026581,22036806,22094872,22110200,22120635,22134138,22158033,22158041,22161326,22199306,22221586,22291433,22293177,22296117,22310285,22311264,22343731,22350412,22404445,22446332,22469187,22492278,22511779,22524983,22547391,22553813,22586611,22632967,22650359,22665064,22675932,22710719,22748924,22763761,22770219,22820506,22823061,22908227,22959436,22970236,22988851,22995332,23029392,23034899,23062638,23077062,23077088,23133524,23184467,23203004,23221544,23221604,23230143,23273568,23301842,23312942,23339869,23382584,23383273,23438793,23440295,23455922,23536577,23543736,23553486,23555276,23559091,23584484,23594796,23602409,23602568,23624368,23665265,23678366,23707388,23718855,23725357,23800691,23815208,23832541,23858559,23896637,23907123,23910095,23946596,23963898,23965337,23966119,23982416,24008375,24018641,24021283,24052415,24067984,24078094,24085301,24098519,24141420,24170542,24185120,24185511,24216315,24243100,24322019,24336114,24336329,24337749,24381057,24423924,24427780,24443386,24457952,24460254,24488669,24504262,24523023,24532476,24574749,24643689,24656158,24667864,24671224,24708177,24727675,24741631,24789280,24806449,24819502,24867101,24920291,24947332,25003467,25032860,25051361,25053516,25053875,25084021,25121353,25143434,25151966,25205053,25205104,25213837,25224768,25228008,25241761,25293778,25310086,25323759,25411243,25412309,25416956,25462566,25490861,25524798,25534318,25536447,25566967,25572801,25578966,25587029,25663461,25666480,25675191,25695279,25733683,25744729,25760044,25788262,25790540,25821107,25824098,25851349,25852190,25894374,25925673,25945542,26044523,26065650,26109559,26186194,26254224,26291312,26313918,26450989,26471266,26496610,26579796,26602816,26613412,26701207,26775844	15		NP_004055.1|MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
109	VTI1B	839208	Vesicle transport v-SNARE 12		ATVTI12|T24P13.5|T24P13_5|VESICAL TRANSPORT V-SNARE 12|VTI12	thale cress	NM_102430.4	NP_564255.1	NC_003070.9	Q9SEL5	NULL	NULL			May function as a v-SNARE responsible for the docking or fusion of transport vesicles within the trans-Golgi network (TGN). May be also involved in retrograde traffic to the cis-Golgi (By similarity). {ECO:0000250}.	At.24378	10888666,11115874,11130712,11739776,12068098,15797025,15919093,17277094,17360696,19251905,19819752,22737156,22923678,24556609,24833385	3		NP_564255.1|MSDVFEGYERQYCELSTNLSRKCHSASVLSNGEEKKGKIAEIKSGIDEADVLIRKMDLEARSLQPSAKAVCLSKLREYKSDLNQLKKEFKRVSSADAKPSSREELMESGMADLHAVSADQRGRLAMSVERLDQSSDRIRESRRLMLETEEVGISIVQDLSQQRQTLLHAHNKLHGVDDAIDKSKKVLTAMSRRMTRNKWIITSVIVALVLAIILIISYKLSH
110	FOXO3	2309	Forkhead box protein O3 {ECO:0000305}	FOXO3	AF6q21|FKHRL1|FKHRL1P2|FOXO2|FOXO3A	human	NM_001455.3,NM_201559.2,XM_005266867.3,XM_005266868.2,XM_011535626.1,XM_011535627.1,XM_011535628.1,XM_011535629.1	NP_001446.1,NP_963853.1,XP_005266924.1,XP_005266925.1,XP_011533928.1,XP_011533929.1,XP_011533930.1,XP_011533931.1	NC_000006.12,NC_018917.2,NT_025741.16,NW_004929328.1	O43524	Cytoplasm, cytosol.  Nucleus.	NULL			Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. {ECO:0000269|PubMed:10102273, ECO:0000269|PubMed:16751106, ECO:0000269|PubMed:21329882}.	Hs.220950	9345057,9479491,9852958,10102273,10783894,11154281,11435445,11884591,11896584,12027802,12107410,12351634,12477932,12881712,12960271,14527951,14551207,14563822,14574404,14702039,14734530,14962911,14976264,14981546,15047604,15084259,15084260,15123239,15126506,15207915,15265780,15322085,15324660,15489334,15509806,15551757,15604093,15604409,15616007,15662024,15674333,15688014,15708996,15798096,15905404,16061480,16100571,16133873,16373335,16571842,16687394,16690749,16709600,16751106,16809346,16888645,16964248,16979636,17044646,17077388,17190839,17234971,17289590,17389761,17452451,17496928,17522055,17558024,17601350,17711846,17726016,17888023,17900262,17940099,17959613,17979178,18032526,18032780,18037997,18055337,18063811,18178829,18193458,18195003,18204439,18239069,18311149,18312651,18344987,18360030,18363870,18385518,18391984,18393360,18458087,18487207,18524825,18572085,18593906,18678662,18685617,18687691,18692812,18756565,18757210,18757300,18765803,18772130,18781224,18787191,18824006,18977241,18978678,18981303,19010793,19050264,19151395,19160093,19188590,19196970,19211844,19244250,19276113,19276163,19285077,19321440,19322201,19324885,19355923,19380174,19415983,19424579,19457552,19460752,19473970,19494111,19533653,19564415,19592618,19608644,19636295,19751111,19793722,19799812,19807657,19911116,19913121,19917721,19933843,19940129,20018851,20018872,20040763,20110348,20169663,20190568,20215543,20219431,20306291,20371605,20371610,20371612,20379614,20562859,20625400,20628086,20631076,20656682,20671123,20677014,20729811,20733005,20808831,20849522,20862322,20868776,20874444,20881262,20884733,20934750,20956937,20966391,20978166,21092744,21138866,21203424,21209944,21216879,21304824,21329882,21336599,21393426,21447726,21452041,21458454,21510935,21532621,21604264,21613825,21621268,21621563,21685924,21690325,21690554,21705328,21708191,21713995,21715626,21725602,21732363,21775285,21777391,21793107,21813271,21841822,21860419,21900206,21909281,21910584,21911455,21915097,21926463,21933986,21965295,22015955,22094256,22107151,22128155,22139133,22159921,22209974,22223847,22310285,22349704,22394200,22411791,22430142,22435562,22451935,22459618,22474286,22474372,22489133,22489168,22515357,22531926,22552808,22582938,22588664,22590725,22714061,22718346,22743331,22748238,22761423,22761832,22761954,22815774,22820736,22833338,22848740,22892845,22893124,22922206,22971992,22978663,23071284,23085518,23250986,23262029,23262295,23278239,23295054,23340844,23378341,23418729,23492774,23509296,23535732,23568341,23580232,23585551,23592131,23603907,23624922,23640897,23665396,23691078,23732517,23828518,23828551,23851496,23855308,23857333,23907459,23920411,23950211,23966291,23967095,23967259,23970205,23975182,23982205,24014251,24021689,24028821,24035192,24047697,24077281,24077289,24123662,24123695,24140020,24158851,24194912,24255178,24257750,24265696,24269635,24284420,24333267,24337611,24360957,24376725,24448243,24450884,24467486,24486593,24489705,24589462,24630930,24684457,24700636,24727891,24766860,24769729,24809632,24858012,24864229,24895270,24920680,24947616,24990963,24994714,25000517,25044111,25047750,25053419,25060657,25069037,25093499,25122426,25162939,25168244,25172912,25174716,25186470,25199915,25202904,25208626,25241761,25261981,25271153,25286764,25323477,25344604,25365249,25421486,25422052,25470293,25470651,25480585,25503443,25546383,25554016,25578861,25609649,25640014,25647415,25648147,25704884,25743813,25745998,25753771,25791921,25802279,25843800,25893985,25913413,25935481,25952685,25993007,26054675,26061565,26089158,26186945,26280018,26318418,26370108,26455863,26638075,26673895	15		NP_001446.1|MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,NP_963853.1|MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,XP_005266924.1|MTVALQKGASGGGPCLKQNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,XP_005266925.1|MRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,XP_011533928.1|MRLPRSLGHGQVRRGGRGRRRGKGERTGVHLLDSPDSTEENSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,XP_011533929.1|MKQYGSVSLGRFLEDPMGGNPGQNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,XP_011533930.1|MRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG,XP_011533931.1|MRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG
111	TER94	36040		TER94	22.26|7.12|Apple|BcDNA.GM02885|BcDNA:GM02885|CDC48|CG2331|DmTER94|DmelCG2331|I|Ter94|Tera|VCP|VCP ATPase|VCP/p97|Vcp|anon-WO2004063362.65|anon-WO2004063362.67|cdc48|dTERA|dVCP|dmTERA|dvcp|l(2)03775|l(	fruit fly	NM_001103779.2,NM_001103780.2,NM_001299332.1,NM_058021.4	NP_001097249.1,NP_001097250.1,NP_001286261.1,NP_477369.1	NT_033778.4	A0A0B4LFZ4,Q7KN62	Cytoplasm. Nucleus.	NULL				Dm.2968	7729689,7929140,9046244,9639875,10373303,10471706,10471707,10564274,10656772,10731132,11131529,11810242,11859409,11969264,12097338,12537568,12537572,12537573,12537574,12537575,14605208,14657277,15899868,16110336,16543254,16652170,17151602,17194782,17569856,17569867,17956857,18355804,18433294,18584029,18590813,19101615,19237597,19286629,19317464,19675129,19704789,19718442,19782090,20410307,20519548,20530634,20585616,20604808,20861518,20865169,21149573,21304887,21343367,21447556,21447707,22036573,22481368,22567011,22577517,22722341,22884528,23316440,23498974,23526974,23583758,23652004,23747190,23790629,24114784,24292889,24332855,24497576,24598157,24793180,24799714,25012699,25242033,25255315,25469707,26167652	12		NP_001097249.1|MDHDGDTRDFMRGYHSEQDEKMKPKDSFDKREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFPGQTGNTSGSGNNLPVNSPGDNGDDDLYS,NP_001097250.1|MDELQLFRGDTVILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFPGQTGNTSGSGNNLPVNSPGDNGDDDLYS,NP_001286261.1|MDHDGDTRDFMRGYHSEQDEKMKPKDSFDKREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQNSAMDDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFPGQTGNTSGSGNNLPVNSPGDNGDDDLYS,NP_477369.1|MADSKGEDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFPGQTGNTSGSGNNLPVNSPGDNGDDDLYS
112	RUNX1	861		RUNX1	AML1|AML1-EVI-1|AMLCR1|CBF2alpha|CBFA2|EVI-1|PEBP2aB|PEBP2alpha	human	NM_001001890.2,NM_001122607.1,NM_001754.4,XM_005261068.3,XM_005261069.3,XM_011529766.1,XM_011529767.1,XM_011529768.1,XM_011529769.1,XM_011529770.1,XR_	NP_001001890.1,NP_001116079.1,NP_001745.2,XP_005261125.1,XP_005261126.1,XP_011528068.1,XP_011528069.1,XP_011528070.1,XP_011528071.1,XP_011528072.1	NC_000021.9,NC_018932.2,NG_011402.2,NT_011512.12,NW_004929426.1	Q01196	Nucleus.	NULL				Hs.149261,Hs.612648	1423235,1427868,1560822,1720541,2845103,7533526,7541640,7651838,7761424,7780150,7795214,7835892,7862156,7891692,7919324,8313895,8334990,8353289,8395054,8413232,8490181,8565077,8622667,8622955,8634147,8700862,8889548,9119228,9199349,9447981,9751710,10068652,10207087,10228168,10404214,10455134,10508512,10521447,10531362,10545320,10675041,10713153,10825294,10830953,10856244,10882117,11118213,11203699,11274169,11276260,11641401,11742995,11792409,11830488,11921279,11965546,11979742,11986950,12002768,12060124,12072207,12082641,12091359,12200707,12217689,12352981,12356919,12377125,12393286,12393523,12393679,12460926,12477932,12495904,12496475,12526921,12554803,12555067,12557226,12560229,12576332,12604126,12643014,12699896,12760263,12773394,12874780,12917624,12937148,14523475,14525764,14561740,14562119,14615365,14623259,14702039,14703694,14729951,14747476,14752096,14966519,14970218,15051730,15061191,15104277,15104290,15142876,15142881,15179033,15184985,15203865,15302935,15331439,15333839,15339695,15386419,15475366,15489901,15613106,15618958,15654961,15688019,15704129,15705784,15723339,15728845,15735013,15741216,15829516,15856017,15897867,15914564,15968309,15970674,15991223,16042694,16102112,16149049,16177090,16213368,16237704,16249223,16278392,16287839,16307024,16314494,16386788,16442267,16474840,16519819,16598304,16616331,16627249,16628190,16652140,16652147,16652416,16673018,16674921,16684349,16702405,16741927,16803898,16821265,16888092,16892559,16914570,16917507,16964375,17015828,17017876,17043020,17072347,17079875,17095626,17213321,17234761,17285576,17377532,17394134,17431401,17485549,17532767,17533375,17550866,17560011,17560331,17589498,17625612,17635584,17650443,17673463,17684492,17690704,17854666,17889709,17889714,17894555,17910630,17935781,17956600,17975013,17989718,17996649,18003885,18029348,18073335,18087673,18166807,18183572,18192504,18202228,18202291,18206538,18206548,18276842,18280240,18316480,18328148,18332109,18337762,18445843,18462252,18478040,18487507,18511808,18519037,18539581,18548094,18622412,18635414,18656694,18663147,18668679,18671852,18687517,18687690,18695000,18701449,18723428,18724045,18728978,18767145,18767146,18768464,18790797,18853425,18925961,18928518,18952841,19001502,19020999,19043539,19100510,19100516,19114653,19129484,19144660,19151769,19158815,19167608,19179469,19282830,19322201,19322702,19328795,19334039,19337732,19351817,19357396,19387465,19403666,19448675,19453261,19454010,19458628,19494111,19497860,19524548,19581587,19585539,19603429,19626042,19638627,19665068,19666867,19773259,19808697,19850737,19896186,19913121,19917773,19946261,19998443,20001241,20008790,20030931,20035012,20096094,20111069,20124335,20181616,20190817,20195544,20197715,20206228,20236534,20306249,20306685,20308320,20339092,20346360,20379614,20395453,20421268,20430957,20439113,20460523,20506188,20520634,20520637,20547749,20589720,20603019,20628086,20678218,20682397,20686504,20688956,20722699,20735389,20807887,20846103,20855863,20880116,20946940,20970160,21029724,21054152,21057539,21059642,21070662,21076613,21088106,21090242,21109770,21129147,21148331,21150319,21166663,21179004,21200020,21204219,21224468,21233836,21252065,21268063,21283084,21292764,21294243,21322790,21325596,21332713,21343560,21380778,21445863,21447743,21468021,21493867,21518930,21571218,21576367,21640801,21642993,21723253,21725049,21764752,21799513,21803869,21822204,21828118,21829377,21836606,21836608,21869842,21873977,21900195,22012064,22021368,22024923,22025082,22028862,22032690,22076464,22081516,22094587,22145956,22163048,22193545,22201794,22221250,22253733,22318203,22343733,22366949,22404039,22419089,22430633,22498736,22542470,22551552,22673192,22689058,22689681,22725134,22748822,22753902,22777353,22828445,22865593,22898599,22919028,22995345,23022380,23028138,23034403,23065512,23086478,23148227,23175372,23223432,23254331,23321257,23327922,23333304,23341344,23344057,23350231,23352661,23372166,23426948,23442798,23443342,23471304,23488608,23527860,23528260,23551011,23667531,23741012,23752268,23753029,23848403,23874874,23958918,23979164,24002588,24007691,24035334,24055056,24100448,24123676,24130502,24240203,24297870,24321385,24327541,24339741,24388988,24390342,24402164,24449215,24456692,24523240,24606315,24616160,24646888,24651404,24673627,24695740,24716598,24727677,24732596,24752773,24756106,24783204,24792891,24897507,24967588,24972750,24973361,25066867,25082877,25101977,25114263,25129146,25135298,25185713,25241761,25263451,25283809,25313057,25388957,25452107,25486427,25490895,25537508,25546363,25562167,25575569,25596267,25612891,25656571,25801305,25879624,25893288,25901786,25911237,26010396,26021490,26161748,26175287,26185316,26214902,26496610,26598521,27100087	15		NP_001001890.1|MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,NP_001116079.1|MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQEEDTAPWRC,NP_001745.2|MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,XP_005261125.1|MPAAPRGPAQGEAAARTRSRDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,XP_005261126.1|MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRNTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,XP_011528068.1|MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,XP_011528069.1|MASDSIFESFPSYPQCFMRDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,XP_011528070.1|MASDSIFESFPSYPQCFMRDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRNTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY,XP_011528071.1|MRGPGRCRARQGGRGGTHGDGSSLRWEGAPPGGVGVGSARRTGGGALRAPRKCPQHRGDRRRGKRPPAREAGETLRWPLTHAASETRGGIEPRPGRSGKKHPLQKPTQGKTLRANGTRGRRPASCKESAPLRRSCQPDGAGARSGSPGPRGQIAPPPWKRRPGPGRPRRIWGRPRAAARFGSLVAATAPACSGSRGRASPGAARRPGPPRAGGACFLFPGLRTVATRGAAQACVWLRKGVRTRAGPRASMQAWMRGAGVASDSPPGLRTVARGAAAGARGPIPGAGGGEPRPG,XP_011528072.1|MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQEEDTAPWRC
113	MTMR14	64419		MTMR14	C3orf29	human	NM_001077525.2,NM_001077526.2,NM_022485.4,XM_005265400.1,XM_011534012.1,XM_011534013.1,XR_245152.1	NP_001070993.1,NP_001070994.1,NP_071930.2,XP_005265457.1,XP_011532314.1,XP_011532315.1	NC_000003.12,NC_018914.2,NG_017068.1,NT_022517.19,NW_004929309.1	Q8NCE2,Q8WYY9	NULL	NULL				Hs.475382	8619474,9110174,11256614,12477932,14702039,15186772,16344560,17008356,19590496,20379614,20595810,21832049,25416956,26186194,26673895	15		NP_001070993.1|MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKRCLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSVDHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL,NP_001070994.1|MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKRCLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL,NP_071930.2|MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKRCLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL,XP_005265457.1|MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKRCLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSVDHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL,XP_011532314.1|MAAGPAALRFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSVDHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL,XP_011532315.1|MARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSVDHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL
114	PRB1	856649	Cerevisin		CVT1	baker's yeast	NM_001178875.1	NP_010854.1	NC_001137.3	P09232	Vacuole.	NULL			Vacuolar proteinase B involved in protein degradation in the vacuole. Among other substrates, acts on carboxypeptidase Y (cpY/PRC1) to activate it by processing its Pro-peptide. Required for meiosis and spore formation, and for optimal survival in stationary phase. {ECO:0000269|PubMed:6764902, ECO:0000269|PubMed:7021321}.		377296,385314,2674123,3325823,6764902,8849441,9169868,9529893,9649520,10436014,10900456,11805837,14764870,15766533,16554755,17899065,18616809,20093466,20641016,21196523,21552543,21777812,21825077,22282571,22940862,22997150,23169651,23222640,23332755,23712011,24389104,24587380,26161950,26217697,26508657,26849847	28		NP_010854.1|MKLENTLFTLGALGSISAALVIPNLENAADHHELINKEDHHERPRKVEFTKDDDEEPSDSEDKEHGKFHKKGRKGQDKESPEFNGKRASGSHGSAHEGGKGMKPKHESSNDDDNDDKKKKPHHKGGCHENKVEEKKMKGKKVKGKKHHEKTLEKGRHHNRLAPLVSTAQFNPDAISKIIPNRYIIVFKRGAPQEEIDFHKENVQQAQLQSVENLSAEDAFFISTKDTSLSTSEAGGIQDSFNIDNLFSGYIGYFTQEIVDLIRQNPLVDFVERDSIVEATEFDTQNSAPWGLARISHRERLNLGSFNKYLYDDDAGRGVTSYVIDTGVNINHKDFEKRAIWGKTIPLNDEDLDGNGHGTHCAGTIASKHYGVAKNANVVAVKVLRSNGSGTMSDVVKGVEYAAKAHQKEAQEKKKGFKGSTANMSLGGGKSPALDLAVNAAVEVGIHFAVAAGNENQDACNTSPASADKAITVGASTLSDDRAYFSNWGKCVDVFAPGLNILSTYIGSDDATATLSGTSMASPHVAGLLTYFLSLQPGSDSEFFELGQDSLTPQQLKKKLIHYSTKDILFDIPEDTPNVLIYNGGGQDLSAFWNDTKKSHSSGFKQELNMDEFIGSKTDLIFDQVRDILDKLNII
115	isp6	2543097	Sexual differentiation process putative subtilase-type proteinase isp6		prb1		NM_001019245.2	NP_593815.1	NC_003424.3	P40903	NULL	NULL					7954893,11115118,11859360,11872168,16550352,16823372,17295836,21153812,23050226	33		NP_593815.1|MRIPYSNLFSAAAGLALFASTACAAPVMPATDSDIAHAGIRPELDNAFYDSHGEAATPKHKPHAGPNAAPLLSASNADTTGLDSHYIIVLQPDLSEQEFQAHTNWVSEMHQMDIASQEDEYYDTSDSNYMFGLKHVYDFGEDSFKGYSGQFSSNIVEQIRLHPHVIAVERDQVVSIKKLETQSGAPWGLARISHKSVKYDDIGKYVYDSSAGDNITAYVVDTGVSIHHVEFEGRASWGATIPSGDVDEDNNGHGTHVAGTIASRAYGVAKKAEIVAVKVLRSSGSGTMADVIAGVEWTVRHHKSSGKKTSVGNMSLGGGNSFVLDMAVDSAVTNGVIYAVAAGNEYDDACYSSPAASKKAITVGASTINDQMAYFSNYGSCVDIFAPGLNILSTWIGSNTSTNTISGTSMATPHVAGLSAYYLGLHPAASASEVKDAIIKMGIHDVLLSIPVGSSTINLLAFNGAQE
120	avt3	2543612	Vacuolar amino acid transporter 3				NM_001018984.2	NP_593551.1	NC_003424.3	Q10074	Endoplasmic reticulum membrane.	NULL			Involved in amino acid efflux from the vacuole to the cytoplasm. Capable of transporting large neutral amino acids including tyrosine, glutamine, asparagine, isoleucine and leucine (By similarity). Required for spore formation. {ECO:0000250, ECO:0000269|PubMed:19778961}.		11859360,16823372,26083598	33		NP_593551.1|MSNSQSIKIKKPRSNENFASGSYSSRRSQQIHRLSHSPMAEGFHKPKLNISPSESNLPNNVAENTTDTPVNYGSIRDENHNSRKGKDVTLNSDEAHSENVPSTSEDPDVVRRHLGGQAADDDNFSSLQLQGGDMHRQVYRWQQEVDQNKQIRRGRSRSFSAKVSDPNLHLRSVQDMKQAGGMRRDFLRNRASSISMSSNAHGNPNFLNRNFIEFLSVYGHFAGEELSEEDEDEDTDDFAMPRDVNPSLIHSTVPSEQEPLISRHGRYKLQTPGNASNGKAVLLLLKSFVGTGVLFLPKAFKLGGLVFSSATLLIVGVLSHICFLLLIQTRMKVPGSFGDIGGTLYGPHMRFAILASIVVSQIGFSSAYISFVASTLQACVKVISTTHREYHLAVFIFIQFLVFVPLSLVRKISKLSATALIADVFILLGILYLYFWDVITLATKGIADVAMFNKTDFSLFIGVAIFTYEGICLILPIQEQMAKPKNLPKLLTGVMAAISLLFISIGLLSYAAFGSKVKTVVILNMPESTFTVIIQFLYAIAILLSTPLQLFPAIAIIEQGIFTRSGKRNRKIKWRKNYLRVLIVILAILISWAGSSRLDLFVSMVGSVCCIPLIYMYPPMLHYKACANNWILRTLDIFMFTIGAFAMAFTTYMTFF
121	avt5	2540081	Vacuolar amino acid transporter 5				NM_001021118.2	NP_595211.1	NC_003423.3	O74327	Vacuole membrane.	NULL			Vacuolar amino acid transporter involved in the vacuolar uptake of histidine, glutamate, tyrosine, arginine, lysine, and serine. Required for sporulation. {ECO:0000269|PubMed:19778961, ECO:0000269|PubMed:20388511}.		11859360,20388511,20699567	33		NP_595211.1|MSGYSPLSSGPADVHIGKAGFFSSVINLANTILGAGILSLPNAFTKTGLLFGCLTIVFSAFASFLGLYFVSQCAARLPRGKASFAAVAKHTFPSLAVVFDASIAVKCFGVAVSYLVIVGDLMPQIAPSLGLSSPMFLRRQTWIVFALFVLTPLSFLKRLDSLRHTSVISLIALCYLVFIVLYHFIIGDTVKGEIRYFVPESGFGYLSVLPVFVFGFTCHQNAFSVINEVRNFSQGFVNFTMFTAIISSTLLYLLVAITGYLSFGSLASGNIIAMYDNTSIWIIGGKLAIVVLVLFSYPLQCHPCRNSVYQAIRRSYSAHDMSDGYHAVITLCILLFTHSLALLLSSLEMVLAFVGSTGSTFISFILPGSLYYFFSHKVASPGNSSPLQLRISRAFAAGLAIYGTVVMILCLNINIAKLSH
122	ams1	2543485	Alpha-mannosidase				NM_001019405.2	NP_593979.1	NC_003424.3	Q9UT61	Cytoplasm. Vacuole.	NULL			Degrades free oligosaccharides in the vacuole. {ECO:0000250}.		11859360,16079177,16823372	33		NP_593979.1|MTLFPVLNNTPVGKQVDSIYESRLDQFLSEGQYRDFNLPSVYDHARIDNPSGDVNNDLSKGFVDLKVYRVPDLSRPSFNEVVGHKKFDETASKGDTFGPSWATFWFEVHIRLPKSWAKYEQVIFQWNCDNEGLVYSQDGVPLQAFSGSERTDFILPDSWKTTEDTFYIEMACNGMFGTGAGSQIAPPDPNRYFTLTKADLVAPNLPAMALAYDFLLMQQCVKQLPSNCWQKYKARQICNDIMNTFHPNDLSTINECRNLAKAFLGNDIDSEAVFEKNNDKANVFAIGHCHIDTAWLWPFAETRRKIVRSWATQMNIMDRYPEYQFVCSQALQYLWLKEDHPDVFEKLKEYVNQNKFIPIGGSWVEHDTNIPNGESLIRQFLLGQHFFEKEFGVRCRTFWLPDTFGYSSQIPQICRLCGMDRFLTQKLSWNNINSFPTSTFNWVALDGSQVICHMPPANTYTADTNVNDVLHSIDQHKNLVNDQAGLLVFGIGDGGGGPTPEMLEKLRRCKGIANTVGYLPNVKLGNTVDEFFDGILKRTNAGQTLPSWNGELYFEFHRGTYTTQAELKKLMRKVEIALHDAEYVSTLASIFSKDYSYPKESLQDLWRDTLLCQFHDVLPGSCIEMVYKDAIPIMSKVLKNTEALLWQAIEQLGFKKASSSDNKEQLCLLNTLPWNVRGVITETEENKLVYFESCDGKGILTAAHTSLKHPAAAYQKDDNFILVNDHLRVTIAPNGLILSLFDLHKEREILDLKSGKNHAGANQYVLFEDTPLSWQAWDTEVFSLEKYEVLDKGKVSIKESGPLRASVVVDIPISELSHMKATISLEGYNDCSEFTGVNFTCEVDWHESCKFLKVEFPVDIHSEFASYETQFGITKRPTHYNTSWDVAKFEVCHQKFADYSDFTYGVSVLNDCKYGFSTHGNLMRLSLLRSPKQPDAHADMGKHTIRYAVYPHSKPLDSSTVRAAHKFNSNFRLLTRASDTANLDIFDAFQLVGEPNVILSHIKMAEKGKSIILRVYESLGGKSRARLVIKSLTVASVTKCNGLEEDLEELCTLKSNDYYEVPIELRAFEIATFKVNL
123	fnx1	2539786	Multidrug resistance protein fnx1		SPBC21D10.04c		NM_001021917.2	NP_596009.1	NC_003423.3	Q09752	Vacuole membrane.	NULL			Efflux transporter. Confers resistance to a variety of toxic compounds. {ECO:0000269|PubMed:9710608}.		9710608,11859360,16823372,18503766,20388511,21436456	33		NP_596009.1|MVDQVNLATEQTSLLYPEVSRKKEELSVNKWTILPALWVGGFLSALDMTIVASLYPVIGSEFKLMNNASYIVTAYLITNTAFQPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGLGTMSSIISSDIVSLRERGTWQGITNIVWGIGGSLGGPLGGLIAQRWGWRTAFHFQVPMGILSTILVAWRVRVKPTVRNSNASLLSRIDYLGSFLLVTGITALVVTFNMGGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPVEILSQPTPLNVCLGNFFNAFCSFVIVYELPLFFETTLLMPSSEAGVRIFPYVISTSVGSLCSGLYMKKTGRYRNLVIAGFFFMLMGIVSFAVLTSFGHRTPLILISLCLAMTGCSYGMNLTSTLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQTTTLSILMKQLASNLKDDPDKDDLIRRLRESISIIPNLPKDIQKLVIKSYATAFTWTFALVAIIAFAGFWCSLRIKQFYLHTSVDRS
124	fnx2	2541016	Vacuolar membrane amino acid uptake transporter fnx2				NM_001022009.2	NP_596093.1	NC_003423.3	O59726	Vacuole.  Membrane.	NULL			MFS-type transporter involved in vacuolar amino acid uptake. {ECO:0000269|PubMed:18503766}.		11859360,16823372,18503766	33		NP_596093.1|MSNPRTKSPNTNRGQGLRSERSALLNDSLSSLNGNSSYDSIKDSSKNNKDVAEVNEYPRRPESSVSVVSNSPHRQDAATTNTVSTVSVSKVLPALLLGVVLAALDNTIVASTYTKIGAEFGKFSQVSWTATAYMISCTAFQPLFGKFCDIYGRKKTLLAAYCVFGIGCFLCGTSRSLWQLVAARAIAGIGGGGMNSTVSILMSDIVPLKQRGTYQGIINVFFAIGSSLGGPVGGYFADQYTWRIGFLIQVPLIAIAFLCVYFTLNLPHHNHVSFMTRFRKIDLKGLILLIIGVTTMTCAFTLGGNVREWNDPVVISLLIASSISYLSFVYVEAFVAFEPLAPMDVLTERTCLSSYLCNFFHSVANFGWIYGMPLFFQSIKNEGAEKSGIRLIPMIIGSSLGSLLGGAVISLTGNYKKITVGSYFFGSVAALFMLRYGYSNFNWEYAVYPFSGGLGNGIAVTTTLVAIIHASPSAFQASAIATSYLFRSNGCVLGVSISSSIVQTVLGIKLRKSLDFDVDELLHHLRKDISYVHRLPEEIRQTVLDALLGSIHYSFLFVSFMFFCAFVCSMFIKNRNL
125	InR	42549	Insulin-like receptor subunit beta 2	InR	18402|CG18402|DIHR|DILR|DIR|DIRH|DIRbeta|DInR|DInr|Dir-a|Dir-b|DmelCG18402|INR|INS|IR|Inr|Inr-alpha|Inr-beta|InsR|dINR|dIR|dIRH|dInR|dInr|dInsR|dinr|dir|er10|inR|inr|insulin/insulin-like growth factor	fruit fly	NM_001144621.3,NM_001144622.2,NM_001144623.2,NM_079712.6	NP_001138093.1,NP_001138094.1,NP_001138095.1,NP_524436.2	NT_033777.3	P09208	Membrane.	NULL			Has a ligand-stimulated tyrosine-protein kinase activity. Required for cell survival. Regulates body size and organ size by altering cell number and cell size in a cell- autonomous manner. Involved in the development of the embryonic nervous system, and is necessary for axon guidance and targeting in the visual system. Also plays a role in life-span determination. {ECO:0000269|PubMed:10455177, ECO:0000269|PubMed:11250149, ECO:0000269|PubMed:11292875, ECO:0000269|PubMed:12702880, ECO:0000269|PubMed:7628438, ECO:0000269|PubMed:8603594}.	Dm.1271	1915852,2454394,3014506,3099787,3118188,3934169,7545165,7628438,7711018,7750456,7876183,8024818,8366341,8393126,8603594,8621681,8628319,8831701,9006070,9255069,9276463,9835652,9883586,10399915,10455177,10470487,10471706,10475855,10491260,10523207,10556061,10559955,10679387,10731132,10790335,10801879,10862736,10934032,10935514,10980431,11128988,11169585,11179818,11250149,11292874,11292875,11294208,11295511,11301264,11348592,11377964,11381037,11390358,11402332,11740932,11752451,11782950,11784000,11832249,11897402,11998690,12147138,12163412,12208851,12386938,12426388,12470891,12537568,12537572,12537573,12537574,12539239,12559758,12636917,12702863,12702880,12871911,12882346,12893776,12908874,14616064,14668372,14677635,15013662,15296714,15454075,15454083,15533947,15565107,15592467,15616552,15707896,15710747,15723055,15734678,15734679,15782175,15820683,15843412,15935772,15944190,15960805,15998720,16086608,16099985,16110336,16143107,16150727,16163709,16172603,16182527,16187303,16198284,16230533,16243018,16332201,16526509,16630820,16730347,17021175,17086199,17125816,17139322,17167488,17183370,17215867,17234883,17256009,17264888,17301792,17398096,17462750,17465980,17569856,17569867,17646657,17658221,17895391,17956857,18068153,18084299,18234213,18245346,18396138,18412985,18489752,18505882,18573871,18632097,18653470,18682802,18690062,18721782,18757933,18820430,18832180,18957936,18972134,19005568,19036722,19064709,19066463,19128792,19136634,19178699,19211682,19216764,19317915,19336466,19336477,19376106,19378453,19384053,19390610,19398492,19412543,19494035,19515698,19543366,19680438,19692410,19696884,19724682,19742324,19778508,19822665,19861550,19910925,19956092,20001959,20005803,20044986,20059956,20061393,20074316,20074523,20100334,20203043,20333234,20346676,20417156,20418542,20447440,20471268,20493190,20504961,20574526,20585550,20621708,20634900,20645870,20739318,20849947,20946983,20951347,20974844,20976250,21040900,21055942,21084378,21145317,21183078,21183483,21267071,21303840,21346761,21385607,21423626,21443682,21447707,21458672,21464442,21516106,21516128,21572965,21613324,21652649,21664581,21680868,21694719,21703546,21707536,21814033,21816278,21907145,21931847,22028469,22049341,22050674,22068330,22085964,22102829,22117545,22132213,22190992,22228302,22240588,22240900,22241840,22242005,22348290,22350798,22357619,22367393,22407365,22411915,22510984,22529821,22570625,22609549,22629134,22645656,22654869,22685490,22715466,22743648,22745312,22751499,22786647,22817988,22829591,22870402,22872808,22876196,22911822,22913798,22925826,22927638,22956542,23019586,23022298,23077061,23087833,23087834,23129806,23132575,23144631,23173097,23236133,23251396,23307869,23339871,23407678,23455472,23477723,23493057,23541587,23549788,23590848,23591813,23624434,23685249,23690177,23732470,23853709,23878722,23885240,23895933,23911328,23935447,23944235,24026119,24035390,24055154,24062693,24068890,24069139,24133012,24133450,24137131,24150648,24191061,24217617,24243023,24278035,24348428,24357227,24357229,24361577,24380076,24385933,24395637,24439370,24439372,24478707,24489769,24500165,24509725,24513978,24530508,24609035,24676055,24680699,24685228,24685612,24690889,24706800,24723892,24752400,24755363,24768030,24778227,24793180,24795642,24795868,24801064,24817759,24845618,24865556,24882358,24902665,24902837,24912777,24937262,24945255,24946019,24949430,25007267,25015062,25017064,25020200,25043021,25058496,25092766,25101872,25126791,25200291,25214494,25232726,25239918,25263556,25280996,25284370,25319083,25356674,25367037,25393288,25421701,25451929,25470527,25472843,25481758,25521289,25523082,25541690,25566097,25581915,25634895,25805973,25850671,25937233,25966593,26020640	12		NP_001138093.1|MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA,NP_001138094.1|MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA,NP_001138095.1|MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA,NP_524436.2|MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA
126	Rheb	117332		Rheb	CG1081|DReb|Dm Rheb|DmRheb|DmelCG1081|Q9VND8|RHEB|RheB|dRheb|rheb	fruit fly	NM_169068.3,NM_169069.3	NP_730950.2,NP_730951.2	NT_033777.3	H1ZYG4,Q9VND8	Endomembrane system.	NULL				Dm.11577	10731132,10753927,12537568,12537572,12537573,12537574,12766775,12766776,12771962,12893813,14579253,14607085,14616073,15084262,15102439,15210936,15240005,15296714,15367757,15454083,15545626,15589139,15707896,15782175,15843412,15985179,15998720,16110336,16278294,16332201,16361227,16461276,16516475,16627617,16630820,16713952,16774996,16785324,17021175,17038544,17043309,17086199,17114577,17139322,17208179,17253963,17301792,17347671,17371599,17398096,17412918,17440611,17569856,17569867,17928404,18067683,18086911,18299344,18474623,18505882,18604198,18653470,18692051,18794330,18854141,19216764,19225150,19262129,19317915,19378453,19531351,19720874,19778508,19789644,19862331,20038815,20203043,20214937,20339376,20362445,20457610,20471268,20478529,20504956,20585550,20585616,20619819,20808898,21151027,21169990,21239477,21267071,21346761,21464442,21516128,21658589,21680868,21816278,21951762,22037307,22068330,22264732,22319582,22350798,22493059,22622177,22654869,22745312,22863314,22911822,22921367,22952930,22960233,23028662,23144631,23144943,23251396,23393158,23444356,23447678,23530222,23532117,23608455,23707736,23843608,23853709,23878397,24068890,24133450,24265594,24357229,24385933,24464041,24558265,24685228,24755363,24809668,24862573,24949430,24953188,25017064,25126791,25210733,25305039,25356674,25361581,25373901,25662449,25977367,26063572,26198204	12		NP_730950.2|MPTKERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQDEYSIFPVQYSMDYHGYVLVYSITSQKSFEVVKIIYEKLLDVMGKKYVPVVLVGNKIDLHQERTVSTEEGKKLAESWRAAFLETSAKQNESVGDIFHQLLILIENENGNPQEKSGCLVS,NP_730951.2|MPTKERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQDEYSIFPVQYSMDYHGYVLVYSITSQKSFEVVKIIYEKLLDVMGKKYVPVVLVGNKIDLHQERTVSTEEGKKLAESWRAAFLETSAKQNESVGDIFHQLLILIENENGNPQEKSGCLVS
127	Tsc1	42862		Tsc1	CG6147|DmelCG6147|TSC|TSC1|dTSC|dTSC-1|dTSC1|dTsc1|dtsc1|rocky|tsc1	fruit fly	NM_058067.3	NP_477415.1	NT_033777.3	Q9VCC9	NULL	NULL				Dm.3097	10052455,10731132,10731134,10806479,11348591,11348592,11377964,11390358,11397651,11686512,11698190,11782950,12172554,12172555,12381661,12445406,12537568,12537572,12537573,12537574,12559758,12563289,12618308,12766775,12766776,12771962,12773160,12908874,12941273,14502294,14505573,14523394,14559897,14605208,14607085,14616073,14645523,15020472,15102439,15186745,15240005,15296714,15331236,15454075,15454083,15466161,15545626,15589139,15630418,15704171,15776001,15843412,15998720,16054033,16110336,16143107,16143599,16219781,16273080,16332201,16341207,16461276,16496002,16627617,16652170,16753569,16785324,16949821,16996266,17038544,17110495,17136098,17139322,17253963,17256009,17301792,17369395,17398096,17440611,17569856,17569867,17967059,18084299,18177722,18299344,18474623,18505882,18653470,18794330,18827008,18854141,18957936,19211682,19214224,19216764,19225150,19317915,19378453,19543366,19546244,19609361,19720874,19723496,19917724,20001959,20038815,20059956,20074523,20203043,20339376,20434990,20463884,20471268,20478298,20504961,20573703,20585550,20808898,20849947,21035763,21239477,21243421,21267071,21311569,21346761,21364671,21555458,21680868,21750678,21816278,21907145,22068330,22264732,22367393,22473013,22493059,22504180,22510984,22555456,22654869,22683826,22745312,22911822,22913798,22921367,22949833,22951642,22956542,23144631,23144943,23251396,23393158,23447678,23583758,23843608,23853709,23878397,23885240,24068890,24133012,24133450,24265594,24268699,24357229,24409421,24558265,24609035,24685228,24755363,24786828,24809668,24949430,24953188,24953654,25210733,25239948,25313405,25329560,25356674,25361581,25373901,25481758,25512509,25866192	12		NP_477415.1|MVIEKIIGDLESNMTLENEEAKRKLVELLSQNKEQWVVKFMLDYFFTTGSQRILEVLVKAQAPHDGYIFDKLDDCLKQSQHRVQSLQVFCFIVRHHPTWLYKIEKHRLIKSVFKLMTHEKEIVPLMSALLCIITLLPIIPNSVPNFLNDLFEVFGHLASWKLQNSNKLPDEKLVHLQLGLQMLFHRLYGMYPCSFIAYLVEFIKRGNGGGIFQHTIKPLLNTVRVHPMLVTATPETEVNNTRWKEMEPHDVVMECANLSLPVLLPETSNEDGSYAYPMTPGYSRMTSNTSNTDYSYQLREFQQSRNVYTRFDSFASGDDVGPIWSPHNEIATTSSGIPLTPTTSFILPLQPAMNSQLMVGMTGSSPPEAAVEATPETTPLKDMRDIKQPGRAVNSHAVRAIFAVSQPSSPMRKDQQSQFSFPDVSREAEESSHSYLEVNRGTAYDRRLSQVIQDRHNVERSVNTPCPSSLPEINSDLSLVGGSVYPSVTQEVAAVCGECNETDRNLCSVGGLHMPTSRSMHQLAKKRRNRMASYSGNGSCADSRSSAAKKASWSTEAENPMRRTKSCSALSGMRQQHLEENDDEADCSSQRQRGENGNTQKTGSRLQRSGRNLAISAPKDTARSCTHASTQTVEGLDSAPAQYENWLIELLLECKEQRIDYERNLLYPQDILDEYIKHAIKANESFDAEQGQLMCLQLEYESYRRSIHAERNRRLMGRSRDKRSLEMERDRLREQLKNFDAKNKDLANKMDQAIRLANERQNIHQEELGEMRAKYQHELEEKKCLRQANDDLQTRLTSELARHKEMNYELESLRGQVFSLGTELQHTQQQADIGLQCKQELARLEAEFIIMGEVQVRCRDRLAEIDNFRARDEELQMLQESSNLELKDLRHSLDEKTSQLESMKHKISDLQAQLANSEKAMTEQKRLLSTVKDEYEEKFKSVNKKYDVQKKIIMQMEEKLMMMMQQPQGTTGHNTCSPDTDRTDIASSIERNSPLSTSLASSESLSASLRSTELKNLHQLVDTPTIPDVLNSMAGGAQFEDEVRPPAVDLASSASTASAINIVPHALDLPSTSGGIGHTLTHPHPHPHLHLQQQQQDQLQ
128	gig	40201		gig	6975|C1|CG6975|DmelCG6975|Gigas|ME 109|TSC2|Tsc2|Tsc2/gig|dTSC2|dTsc2|gig|Tsc2|l(3)109|tsc2	fruit fly	NM_001275160.1,NM_079453.3	NP_001262089.1,NP_524177.1	NT_037436.4	M9PD17,Q9VW83	NULL	NULL				Dm.2047	6790324,7965385,8000567,9437021,10052455,10518988,10637629,10679387,10731132,10862736,10980431,11348591,11348592,11377964,11390358,11397651,11487649,11686512,11698190,11782950,12172554,12172555,12381661,12445406,12537568,12537572,12537573,12537574,12559758,12563289,12618308,12766775,12766776,12771962,12773160,12941273,14505573,14523394,14559897,14607085,14616073,14645523,15020472,15102439,15110045,15186745,15240005,15296714,15331236,15454075,15466161,15545626,15589139,15630418,15843412,16054033,16110336,16219781,16273080,16332201,16336044,16387886,16439203,16461276,16496002,16516475,16627617,16648646,16713952,16785324,17038544,17086199,17110495,17136098,17139322,17208179,17440611,17569856,17569867,17928404,17967059,18084299,18171476,18381890,18474623,18505882,18604198,18653470,18762023,18794330,18827008,18854141,19141596,19211682,19216764,19225150,19317915,19363474,19378453,19543366,19609361,19720874,19723496,19917724,20001959,20038815,20059956,20203043,20444419,20463884,20471268,20478298,20478529,20573703,20585550,20619819,20808898,20849947,21035763,21239477,21243421,21267071,21346761,21364671,21555458,21680868,21816278,21907145,22028469,22264732,22493059,22498699,22504180,22555456,22817988,22911822,22927638,22949833,22951642,22952930,23144631,23144943,23251396,23393158,23444356,23447678,23843608,23853709,23878397,23934892,24068890,24133012,24133450,24265594,24268699,24357229,24409421,24529380,24531791,24609035,24661984,24685228,24685612,24755363,24809668,24949430,25220459,25239948,25313405,25329560,25356674,25361581,25373901,25704823,25826386,25826530	12		NP_001262089.1|MNSKDKSKFKLFLKSLPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNHEAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKRQLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYRMSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDSPLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGNDIEELANTLLKINLVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSNAKMLSSDIVNLNSLNEDSSNRKRSTSLTERGSRNNANAWNDLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENSSAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIMLDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTISGQFNYACVIVEPLDLNSNRVYVKARSEISKFVCHAEYRIVSDRSAPLLARQMALHANLASLVYQSVQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGINASAIGSDMDDQRGDFIKYT,NP_524177.1|MNSKDKSKFKLFLKSLPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNHEAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKRQLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYRMSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDSPLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGNDIEELANTLLKINLVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSIQSNAKMLSSDIVNLNSLNEDSSNRKRSTSLTERGSRNNANAWNDLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENSSAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIMLDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTISGQFNYACVIVEPLDLNSNRVYVKARSEISKFVCHAEYRIVSDRSAPLLARQMALHANLASLVYQSVQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGINASAIGSDMDDQRGDFIKYT
130	CG12772	31803		CG12772	DmelCG12772|FBgn 30055	fruit fly	NM_001272419.2,NM_132268.2	NP_001259348.1,NP_572496.1	NC_004354.4	Q9W3C9	NULL	NULL				Dm.13223	10731132,12537568,12537572,12537573,12537574,12909364,16110336,17435224,17569856,17569867,19401399,20500887,24389064	12		NP_001259348.1|MTTPPPPPTLASDAIEGAVYAAGEALHHQHDHPQQQQQQQQQQQLARNSLLADLRRSTNFWFRAAKSTDGLQLLAQSCTRILQHGLLQPVELRRLADDFEFLLASAGKQQQQTKPQPYRPDYAARDSASMVNGVEEFLGEWTTRCLRARCLSQCLQTLVSDPELMELYYPSEEAFLRRSGDATALFVCLTAVQLNQSGLLSQLEVRHQVRHRRTCSQPNFSISPKLQAVPEERLQKRIFLRRLKSLPNLSQEDEELDDRAAFRRRCQTFSSSRSHKLREDHLDAPSTSSCSSHDSPRRIQLINCDDIKIWTDQTPQEVPEEVHEKLQQASKASTSVGGYLGSFFGSPPLYTSWFHRGVGDDLNASGDGGMLDTFLPVNGRKLKKQHTLFEGVSMLDEAASSTACISSAPWDIQGSAGDSTTSTTASSSVSITPGSDKMDQQSLASFLQMSRQTHNNTQLEKENAHFRISEACITAIEHVKWSRRLATPAGPTSHNLSEPNLMPYAEQIPGGGMQNHSAEAVGLQLISRFSEQQLPRLGHLKWLVSEQEAPQQLLPLPTPKQDHEQASLTRGTSSWAPPRQQIIFTEHPSESRSKVLQKQNHRCAGCGMRVAKHLQQHFRYCTYLGKYLCTGCHRNQISAIPARILRSWDFRCYPVCSFAYRLIEQMYAFPLFHVPDLNSQLYKHKELAKARKRRLQLQAVKGFIANCRFATREQSFFNAIPAHITQDPDMWSMCDFVDVQNTSMNRSIKEVIALSEQHVHNCVLCTGRAFVCEHCKGGELIYPWQRKVQRCDRCGACFHNGCWKVRSRCRNQNDPCPRCSRLQSRAS,NP_572496.1|MTTPPPPPTLASDAIEGAVYAAGEALHHQHDHPQQQQQQQQQQQLARNSLLADLRRSTNFWFRAAKSTDGLQLLAQSCTRILQHGLLQPVELRRLADDFEFLLASAGKQQQQTKPQPYRPDYAARDSASMVNGVEEFLGEWTTRCLRARCLSQCLQTLVSDPELMELYYPSEEAFLRRSGDATALFVCLTAVQLNQSGLLSQLEVRHQVRHRRTCSQPNFSISPKLQAVPEERLQKRIFLRRLKSLPNLSQEDEELDDRAAFRRRCQTFSSSRSHKLREDHLDAPSTSSCSSHDSPRRIQLINCDDIKIWTDQTPQEVPEEVHEKLQQASKASTSVGGYLGSFFGSPPLYTSWFHRGVGDDLNASGDGGMLDTFLPVNGRKLKKQHTLFEGVSMLDEAASSTACISSAPWDIQGSAGDSTTSTTASSSVSITPGSDKMDQQSLASFLQMSRQTHNNTQLEKENAHFRISEACITAIEHVKWSRRLATPAGPTSHNLSEPNLMPYAEQIPGGGMQNHSAEAVGLQLISRFSEQQLPRLGHLKWLVSEQEAPQQLLPLPTPKQDHEQASLTRGTSSWAPPRQQIIFTEHPSESRSKVLQKQNHRCAGCGMRVAKHLQQHFRYCTYLGKYLCTGCHRNQISAIPARILRSWDFRCYPVCSFAYRLIEQMYAFPLFHVPDLNSQLYKHKELAKARKRRLQLQAVKGFIANCRFATREQSFFNAIPAHITQDPDMWSMCDFVDVQNTSMNRSIKEVIALSEQHVHNCVLCTGRAFVCEHCKGGELIYPWQRKVQRCDRCGACFHNGCWKVRSRCRNQNDPCPRCSRLQSRAS
131	lqf	38846		lqf	0110/27|CG8532|DmelCG8532|E(faf)bE25|Epsin|LqF|Lqf|anon-WO0118547.239|dEpsin|epsin|l(3)S011027	fruit fly	NM_001104059.2,NM_001274596.1,NM_001274597.1,NM_001274598.1,NM_001274599.1,NM_001274600.1,NM_001274601.1,NM_079238.3,NM_168219.1,NM_168220.1,NM_168221	NP_001097529.1,NP_001261525.1,NP_001261526.1,NP_001261527.1,NP_001261528.1,NP_001261529.1,NP_001261530.1,NP_523962.2,NP_729266.2,NP_729267.1,NP_729268	NT_037436.4	A8JNM3,M9PBU6,M9PEF2,M9PEM7,Q7KU90,Q7KU93,Q9VS85	NULL	NULL				Dm.2223	9332974,9409831,10725248,10731132,10798391,10898994,11697879,11782945,11825870,12121618,12194846,12461563,12537568,12537572,12537573,12537574,12747835,12850443,12932322,14605208,15469967,15469974,15539484,15575970,15620635,15694383,15930117,16110336,16204451,16702236,17074801,17084358,17179082,17569856,17569867,17620409,18057029,18256200,18299346,18439406,18728778,18796008,19305132,19401399,20008933,20214937,20226669,20410139,20493818,20861518,21350007,21448287,22265678,23050227,23487316,23571220,23840387,23973209,24711428,25687947	12		NP_001097529.1|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQQNNNMPWIKPEAATNPFLS,NP_001261525.1|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPSMEAWTLK,NP_001261526.1|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS,NP_001261527.1|MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPSMEAWTLK,NP_001261528.1|MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS,NP_001261529.1|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS,NP_001261530.1|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPSMEAWTLK,NP_523962.2|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS,NP_729266.2|MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS,NP_729267.1|MQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEEGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS,NP_729268|
132	Eip93F	44936		Eip93F	CG18389|DmelCG18389|E93|Eip93|Eip93f|anon-WO02059370.58|eip93f|l(3)93|l(3)ry93|lincRNA.833|psg11	fruit fly	NM_001104395.2,NM_001275888.1,NM_143745.3	NP_001097865.1,NP_001262817.1,NP_652002.2	NT_033777.3	A0A0B4KHV1,Q7YU18,Q9VD60	NULL	NULL				Dm.21704	1849859,6289435,7550245,7556910,7954827,8521511,8603594,8783940,8913033,9264248,9521911,10078197,10354477,10419696,10731132,10772791,10882130,10983989,11102824,11262243,11494315,11703937,11976954,12095613,12297099,12453466,12537568,12537572,12537573,12537574,12548287,12593803,12593804,12852852,12970673,14668412,15082536,15221030,15572132,15657059,15943864,16110336,16264191,16324723,16337999,17256009,17339378,17339382,17569856,17569867,17679695,17761811,17937502,17948312,18056427,18327787,18330897,18353099,18653470,19214204,19841092,20023167,20063412,20702563,20813047,21856777,22085964,22308414,22422652,22427741,22913798,22935612,23077599,23209440,23652443,24170736,24316411,24336022,24374353,24685159,24778249,24949430,25008785,25687947,25824290	12		NP_001097865.1|MADCSYVRCQQERRLIKKKLLKWSTDMLHIVALERVAEECMGRRQWKHYQDKLTCSHLNIEEQQPIAIAGSEDEPSQYNHSSKEISQSNPNHCKTENHRLEQQHNGSQLLEEEDSENNQTSHDSSRTPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSSTSNSHIHQHDSDSNSSASLPHHISSSSSSNNNSSGNRARHIAAASARATPAAATPANSLELYKLLTQRAAKMTSMDSMAAQLAQFSLLADFNLINSLASQQQQQQQQQIASAVTPTTSEVSAAAISPALKDTPSPSVDAPLDLSSKPSPNSSISGDVKSVRACATPTPSGRRAYSEEDLSRALQDVVANKLDARKSASQHHEQRSILDNRLFKMKHHDQEQDHDGDELEDSNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVDRGSPKMGRHPACGNASANQGAPPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDFIKGLLVANSGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRLPKSETPETNSSLDPNDASEDPILKIPSFKVSGPASSSSLSPGGLVGGHHHPLNNNNSLSISNNSNHSSNSHRNGSNRSPHSASPMLAAAVAQGGYSAGNSLLTSSSSSIQKMMASNIQRQINEQSGQESLRNGNVSDCSSNNGGSSSLGYKKPSISVAKIIGGTDTSRFGASPNLLSQQHHSAHHLTHQQQQQQLSAQEALGKGTRPKRGKYRNYDRDSLVEAVKAVQRGEMSVHRAGSYYGVPHSTLEYKVKERHLMRPRKREPKPQPDLVGLTGPANKLQLDKLKAGPHGGSKLSNALKNQNNQAAAAAAAAAAAAAAATPNGLKLPLFEAGPQALSFQPNMFWPQTNATNAYGLDFNRITEAMRNPQASNHHGLMKSAQDMVENVYDGIIRKTLQASEGNGSAAGNGSNGSNGNGHGHGHGHGHALLDQLLVKKTPLPFTNHRNNDYAATCSSASGESVKRSGSPMGNYADIKRERLSADSGGSSDEEHSASHINNNNSDLAHNKNKSGGGGGGGGNGQTNGNGRSSRMTSRDDSETDASSLKSGESGGQQNHKMMDLNGGSSSSSHIKCESEAATGHHSPGHHTTSILHEKLAQIKAEQVDQADQL,NP_001262817.1|MHISSYEISLERVAEECMGRRQWKHYQDKLTCSHLNIEEQQPIAIAGSEDEPSQYNHSSKEISQSNPNHCKTENHRLEQQHNGSQLLEEEDSENNQTSHDSSRTPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSSTSNSHIHQHDSDSNSSASLPHHISSSSSSNNNSSGNRARHIAAASARATPAAATPANSLELYKLLTQRAAKMTSMDSMAAQLAQFSLLADFNLINSLASQQQQQQQQQIASAVTPTTSEVSAAAISPALKDTPSPSVDAPLDLSSKPSPNSSISGDVKSVRACATPTPSGRRAYSEEDLSRALQDVVANKLDARKSASQHHEQRSILDNRLFKMKHHDQEQDHDGDELEDSNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVDRGSPKMGRHPACGNASANQGAPPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDFIKGLLVANSGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRLPKSETPETNSSLDPNDASEDPILKIPSFKVSGPASSSSLSPGGLVGGHHHPLNNNNSLSISNNSNHSSNSHRNGSNRSPHSASPMLAAAVAQGGYSAGNSLLTSSSSSIQKMMASNIQRQINEQSGQESLRNGNVSDCSSNNGGSSSLGYKKPSISVAKIIGGTDTSRFGASPNLLSQQHHSAHHLTHQQQQQQLSAQEALGKGTRPKRGKYRNYDRDSLVEAVKAVQRGEMSVHRAGSYYGVPHSTLEYKVKERHLMRPRKREPKPQPDLVGLTGPANKLQLDKLKAGPHGGSKLSNALKNQNNQAAAAAAAAAAAAAAATPNGLKLPLFEAGPQALSFQPNMFWPQTNATNAYGLDFNRITEAMRNPQASNHHGLMKSAQDMVENVYDGIIRKTLQASEGNGSAAGNGSNGSNGNGHGHGHGHGHALLDQLLVKKTPLPFTNHRNNDYAATCSSASGESVKRSGSPMGNYADIKRERLSADSGGSSDEEHSASHINNNNSDLAHNKNKSGGGGGGGGNGQTNGNGRSSRMTSRDDSETDASSLKSGESGGQQNHKMMDLNGGSSSSSHIKCESEAATGHHSPGHHTTSILHEKLAQIKAEQVDQADQLXEQPMAANPAFAWPPLAAHYYSF,NP_652002.2|MHISSYEISLERVAEECMGRRQWKHYQDKLTCSHLNIEEQQPIAIAGSEDEPSQYNHSSKEISQSNPNHCKTENHRLEQQHNGSQLLEEEDSENNQTSHDSSRTPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSSTSNSHIHQHDSDSNSSASLPHHISSSSSSNNNSSGNRARHIAAASARATPAAATPANSLELYKLLTQRAAKMTSMDSMAAQLAQFSLLADFNLINSLASQQQQQQQQQIASAVTPTTSEVSAAAISPALKDTPSPSVDAPLDLSSKPSPNSSISGDVKSVRACATPTPSGRRAYSEEDLSRALQDVVANKLDARKSASQHHEQRSILDNRLFKMKHHDQEQDHDGDELEDSNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVDRGSPKMGRHPACGNASANQGAPPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDFIKGLLVANSGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRLPKSETPETNSSLDPNDASEDPILKIPSFKVSGPASSSSLSPGGLVGGHHHPLNNNNSLSISNNSNHSSNSHRNGSNRSPHSASPMLAAAVAQGGYSAGNSLLTSSSSSIQKMMASNIQRQINEQSGQESLRNGNVSDCSSNNGGSSSLGYKKPSISVAKIIGGTDTSRFGASPNLLSQQHHSAHHLTHQQQQQQLSAQEALGKGTRPKRGKYRNYDRDSLVEAVKAVQRGEMSVHRAGSYYGVPHSTLEYKVKERHLMRPRKREPKPQPDLVGLTGPANKLQLDKLKAGPHGGSKLSNALKNQNNQAAAAAAAAAAAAAAATPNGLKLPLFEAGPQALSFQPNMFWPQTNATNAYGLDFNRITEAMRNPQASNHHGLMKSAQDMVENVYDGIIRKTLQASEGNGSAAGNGSNGSNGNGHGHGHGHGHALLDQLLVKKTPLPFTNHRNNDYAATCSSASGESVKRSGSPMGNYADIKRERLSADSGGSSDEEHSASHINNNNSDLAHNKNKSGGGGGGGGNGQTNGNGRSSRMTSRDDSETDASSLKSGESGGQQNHKMMDLNGGSSSSSHIKCESEAATGHHSPGHHTTSILHEKLAQIKAEQVDQADQL
133	hep	32256		hep	CG2190|CG4353|D-MKK7|DHEP/MKK7|DJNKK|DMKK7|DmelCG4353|HEP|HEP/MKK7|Hep|Hep/Mkk7|JNKK|MAP2K7|MAPKK|MKK7|Mkk7|dJNKK|dMKK7|hem|hep/JNKK|hp|hrp|l(1)7P1|l(1)G0107|l(1)G0208	fruit fly	NM_001272571.2,NM_001272572.2,NM_001298253.1,NM_078587.3,NM_167346.2	NP_001259500.1,NP_001259501.1,NP_001285182.1,NP_511142.2,NP_727661.1	NC_004354.4	M9PEF9,M9PH06,Q23977,X2JJV1	NULL	NULL				Dm.5867	2499512,8521475,8723337,8946915,8946916,9207092,9224721,9224722,9285703,9312105,9328834,9381174,9388784,9405368,9448464,9472024,9584193,9674432,9694801,9808621,9858699,10047521,10047950,10048301,10208418,10322111,10323867,10364162,10408443,10427090,10433922,10449347,10469646,10490662,10556060,10556069,10557109,10581276,10634792,10731132,10757786,10801428,10822261,10878576,10884420,10903184,10903185,10908587,10985385,11102803,11257223,11287182,11316611,11402332,11468292,11494317,11526075,11543614,11703947,11719206,11784101,11825878,11865058,11868902,11912189,11961558,12000787,12015961,12065414,12110163,12135916,12147138,12198495,12231351,12324941,12351623,12413899,12414186,12431377,12447392,12470891,12537568,12537572,12537573,12537574,12676357,12677046,12728280,12874122,12975351,14519762,14585960,14592975,14602080,14605208,14624240,14668378,14691535,15066286,15084254,15102441,15196554,15197160,15250826,15363413,15381778,15457211,15469838,15634694,15766749,15788564,15798200,15820683,15827086,15922834,15932641,15936337,16002472,16052209,16079232,16110336,16118195,16150723,16170305,16198331,16273080,16281037,16317725,16369482,16391236,16451733,16455799,16496002,16542414,16700059,16753569,16763552,16831834,16875661,16888342,16930585,16933974,16996061,17032066,17082773,17090721,17166915,17183370,17277363,17301221,17343912,17356067,17483425,17531976,17569856,17569867,17573067,17616927,17658258,17765686,17879315,17936269,17950580,18039880,18068152,18233955,18312214,18394890,18407067,18474356,18519585,18524906,18845846,18927396,18940735,19028667,19048077,19064708,19084594,19164706,19194501,19244279,19289090,19390610,19427848,19464045,19540338,19563763,19627268,19641625,19720829,19737745,19745814,19797770,19822734,19840402,19888449,19893628,19934041,20014406,20035736,20072127,20100334,20153725,20203043,20215351,20404112,20490898,20496123,20530545,20541542,20543996,20574526,20627080,20813047,20813879,20876565,20933214,20951347,20976250,21102643,21109026,21148307,21167805,21331775,21333721,21512585,21844890,21878507,21949710,21963537,21963538,21979942,21986496,22190992,22275438,22307950,22326868,22368770,22412942,22479597,22498775,22509270,22666340,22701808,22722927,22802725,22848763,22925826,22976306,22992958,23124073,23172856,23177739,23239028,23264732,23266957,23284287,23570874,23593018,23613593,23633961,23644660,23726905,23748611,23831567,23846225,23944235,24035390,24066226,24136228,24162658,24184102,24268699,24335260,24380076,24585718,24598157,24916379,24981286,25025279,25089524,25160612,25284370,25299777,25345385,25395664,25453105,25522254,25583514,25594180,25657321,25695602,25710168,25719210,25737837,25790850,25794683,25798905,25855961,25880195,25950467	12		NP_001259500.1|MSTIEFETIGSRLQSLEAKLQAQNESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRATATGSAIGSGAGSLAGSGSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAGIGDLNRLYRKSPFMQRKLSNGSHHPHYKYNDESPKKESMFSSIGQSILRNLTTSPFSQKKHNSTATTIPLPHNNQTLITDAATAAAAAATATTPPNIAATVLTTTPTTTPTWRLPTENSQAYDSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTESPTLQLTSQQQQQPQRLQPGNQSPIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTSTNPFHSNYVPPPPSTHSTSSQSSTQSTCSQIAINPASISPSSGSGTGNMAGLGIGSAPASGLGAAGHFGAGGTGEQLQYQPLPIAAEATGTSPTLQSRSPEQQSDYGGNGNMVASKLSKLYARRQLLGQSSSSGASNSSLDGCSREQHDAATSPVASSMDRDQEPVHPQPPAYRSVVNNGSGGKSYYYRTLSAASSSSNTSQSTSPTTEPLPGGGTSSFLRRYASSGPGGSISTPPSPHILAGLDRRHRSPDPPPRYNRGQSPLLLRKNLLELSGQPPGSPLLHRRYVSASPPLPPPRRGSESVPGSPQHFRTRIHYTPEPQRRIYRTIDQXVALQIMVM,NP_001259501.1|MSTIEFETIGSRLQSLEAKLQAQNESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRLPNS,NP_001285182.1|MSTIEFETIGSRLQSLEAKLQAQNESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRATATGSAIGSGAGSLAGSGSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAGIGDLNRLYRKSPFMQRKLSNGSHHPHYKYNDESPKKESMFSSIGQSILRNLTTSPFSQKKHNSTATTIPLPHNNQTLITDAATAAAAAATATTPPNIAATVLTTTPTTTPTWRLPTENSQAYDSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTESPTLQLTSQQQQQPQRLQPGNQSPIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTSTNPFHSNYVPPPPSTHSTSSQSSTQSTCSQIAINPASISPSSGSGTGNMAGLGIGSAPASGLGAAGHFGAGGTGEQLQYQPLPIAAEATGTSPTLQSRSPEQQSDYGGNGNMVASKLSKLYARRQLLGQSSSSGASNSSLDGCSREQHDAATSPVASSMDRDQEPVHPQPPAYRSVVNNGSGGKSYYYRTLSAASSSSNTSQSTSPTTEPLPGGGTSSFLRRYASSGPGGSISTPPSPHILAGLDRRHRSPDPPPRYNRGQSPLLLRKNLLELSGQPPGSPLLHRRYVSASPPLPPPRRGSESVPGSPQHFRTRIHYTPEPQRRIYRTIDQ,NP_511142.2|MSTIEFETIGSRLQSLEAKLQAQNESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRLPNS,NP_727661.1|MSTIEFETIGSRLQSLEAKLQAQNESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRATATGSAIGSGAGSLAGSGSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAGIGDLNRLYRKSPFMQRKLSNGSHHPHYKYNDESPKKESMFSSIGQSILRNLTTSPFSQKKHNSTATTIPLPHNNQTLITDAATAAAAAATATTPPNIAATVLTTTPTTTPTWRLPTENSQAYDSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTESPTLQLTSQQQQQPQRLQPGNQSPIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTSTNPFHSNYVPPPPSTHSTSSQSSTQSTCSQIAINPASISPSSGSGTGNMAGLGIGSAPASGLGAAGHFGAGGTGEQLQYQPLPIAAEATGTSPTLQSRSPEQQSDYGGNGNMVASKLSKLYARRQLLGQSSSSGASNSSLDGCSREQHDAGWFNTLAGAMKRQFATYVKTQLNSTATSPVASSMDRDQEPVHPQPPAYRSVVNNGSGGKSYYYRTLSAASSSSNTSQSTSPTTEPLPGGGTSSFLRRYASSGPGGSISTPPSPHILAGLDRRHRSPDPPPRYNRGQSPLLLRKNLLELSGQPPGSPLLHRRYVSASPPLPPPRRGSESVPGSPQHFRTRIHYTPEPQRRIYRTIDQ
134	bsk	44801		bsk	BSK|Bsk|CG5680|D-JNK|D-junk|DBSK/JNK|DJNK|DJNK/bsk|DmelCG5680|JNK|JNK/SAPK|Jnk|Junk|SAPKa|dJNK|jnk|pJNK	fruit fly	NM_001169459.1,NM_001169461.3,NM_164900.3	NP_001162930.1,NP_001162932.1,NP_723541.1	NT_033779.5	E1JHD6,P92208	Cytoplasm.	NULL				Dm.1448	7588072,7774017,8405984,8514131,8628256,8946915,8946916,9153394,9224720,9224721,9224722,9224723,9285703,9328834,9381174,9388784,9425352,9448464,9472024,9584193,9674432,9694801,9808621,9858699,10022918,10047521,10047950,10048301,10085257,10208418,10322111,10322485,10323867,10339422,10399915,10427090,10449347,10449360,10469646,10471707,10475855,10502111,10507837,10556060,10556061,10557109,10601009,10617573,10634792,10683140,10731132,10744979,10757786,10801428,10801879,10878576,10878822,10903144,10903184,10903185,10908587,10924470,10985385,11212302,11283698,11287182,11316611,11331897,11402332,11439243,11472834,11489639,11509232,11543614,11702944,11703923,11703947,11742539,11784101,11825878,11865058,11868902,11900973,11912189,11959832,11976688,12000787,12012234,12015117,12015961,12065414,12091301,12110163,12135916,12137730,12147138,12176339,12198495,12231350,12231351,12325120,12350339,12351623,12354665,12385750,12413899,12414186,12415279,12429700,12453405,12467587,12470891,12504027,12508287,12537568,12537572,12537573,12537574,12676357,12728280,12766944,12874122,12900440,12941274,12941693,12967554,12975351,14502295,14504224,14519762,14585960,14588244,14592975,14602080,14602681,14603309,14605208,14706698,14707132,14980217,15032585,15037551,15084254,15102441,15182690,15197160,15250826,15254235,15269788,15306851,15457211,15514678,15575970,15582780,15591127,15596544,15640802,15647755,15678745,15704109,15708556,15760463,15766749,15774763,15776001,15788564,15820683,15827086,15831751,15922834,15932641,15965261,15968584,16002472,16041752,16052209,16079158,16079232,16081424,16110336,16116462,16118195,16150723,16198331,16254241,16273080,16317725,16339186,16359857,16369482,16391236,16451733,16455799,16496002,16542414,16611691,16621891,16753569,16763552,16815332,16875661,16887822,16888342,16919444,16930585,17000765,17027478,17032066,17034783,17055976,17082773,17090721,17110495,17121811,17218455,17227793,17277363,17301221,17343912,17356067,17483425,17492752,17531976,17569856,17569867,17588928,17616927,17658258,17765686,17879315,17915206,17950580,17994084,18056427,18067683,18068152,18084299,18233955,18246068,18286519,18344986,18385808,18394890,18394891,18407067,18430930,18430932,18456458,18516287,18519585,18524906,18538428,18547166,18562277,18632567,18694958,18716220,18775745,18815370,18820468,18820472,18832361,18836313,18927396,18940735,19026547,19028667,19064708,19084594,19164706,19176529,19194501,19225150,19243220,19247932,19289090,19348653,19366729,19382940,19390610,19406101,19427848,19464045,19473727,19540338,19563762,19563763,19627268,19646875,19720829,19727075,19745814,19778415,19786572,19797770,19805631,19812789,19838331,19840402,19861550,19888449,19893628,19934041,20008933,20014406,20035736,20043942,20066009,20072127,20080168,20100334,20117206,20153725,20178599,20184864,20203043,20209437,20215351,20374622,20375590,20381350,20404112,20418542,20453880,20473027,20490898,20496123,20541542,20543996,20574526,20600624,20627081,20642455,20643350,20644714,20645870,20655917,20668515,20724829,20736302,20813260,20813879,20817925,20849943,20849947,20921142,20933214,20946983,20951347,20952447,20976250,21045109,21062384,21076039,21145886,21148307,21176204,21177347,21183483,21234801,21364671,21368274,21378980,21385866,21389055,21397843,21406223,21512585,21561986,21664581,21669933,21672235,21730059,21810906,21829386,21844890,21857667,21878507,21886179,21948705,21949710,21949861,21955824,21963538,21979942,21979943,21986496,21987827,22036573,22065747,22101275,22114909,22134547,22153373,22190496,22190992,22197814,22227521,22262460,22307950,22312004,22326868,22355724,22363408,22368770,22371299,22374403,22388889,22393355,22426530,22446736,22449966,22467874,22479597,22498775,22509270,22575490,22580825,22679484,22701670,22701808,22722927,22733771,22802725,22832276,22843669,22848763,22858408,22890320,22900232,22902989,22925826,22939627,22952763,22954894,22976306,22992958,23023132,23056407,23063437,23077619,23093933,23102700,23108407,23124073,23184991,23196366,23227189,23239028,23264732,23306653,23335205,23412656,23418496,23449394,23471010,23471909,23509066,23549790,23550134,23555310,23593018,23618811,23644660,23726905,23796903,23802043,23821035,23827194,23831567,23846225,23853709,23878275,23885240,23904612,23911328,23959949,24002645,24010524,24023255,24029952,24035390,24058767,24062693,24066226,24068890,24069566,24069567,24104056,24136228,24137131,24184102,24198375,24268699,24335260,24380076,24381562,24385865,24392358,24409421,24412365,24497843,24498174,24531729,24553922,24555652,24583474,24585718,24586740,24598157,24641887,24662564,24673174,24676055,24680699,24685611,24685612,24701963,24705267,24752236,24755363,24780858,24788409,24790636,24795868,24799191,24819147,24819984,24856462,24942366,24946019,24948796,24949430,24981286,24995985,25012819,25025279,25089524,25093834,25114797,25142568,25160612,25217223,25224221,25226030,25241934,25281658,25284370,25299777,25307481,25313405,25344916,25345385,25421599,25522254,25530181,25583514,25594180,25601202,25624491,25695602,25710168,25719210,25726747,25753035,25754635,25762498,25798905,25855961,25950467,25968311,26222204,26377800,26586184	12		NP_001162930.1|MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR,NP_001162932.1|MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR,NP_723541.1|MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR
135	Jra	36057		Jra	AP-1|AP1|CG2275|D-Jun|D-jun|D-jun/Jra|DJUN|DJun|DM14|Djun|DmelCG2275|JRA|JUN|Jun|V|c-Jun|cJun|d-JRA|d-Jun|d-jun|dAP-1|dJRA|dJUN|dJra|dJun|djun|dm-Jun|jra|jun|l(2)46Ef|l(2)IA109|l(2R)IA109	fruit fly	NM_001273915.2,NM_057238.5,NM_165739.2	NP_001260844.1,NP_476586.1,NP_724882.1	NT_033778.4	A0A0B4KEI6,P18289	Nucleus.	NULL				Dm.3574	1339674,1652801,1696724,2116361,3149584,3215512,7588072,7732572,7749324,7789766,7867504,7923366,8082742,8218421,8521492,8543167,8670899,8946915,8946916,9106169,9155027,9224720,9224721,9224723,9232604,9285703,9310330,9328834,9334280,9342356,9381174,9388784,9425352,9431804,9448464,9584193,9674432,9694801,9808621,10047521,10047950,10048301,10085257,10433922,10449347,10469646,10491260,10518507,10557109,10612401,10634792,10637629,10716948,10731132,10771085,10801428,10805795,10903184,10903185,10924470,10929403,10935514,10949024,10985385,11167131,11223240,11287182,11311164,11331897,11402332,11432740,11439243,11509232,11543614,11554782,11606746,11702944,11810242,11825878,11865058,11900973,11959832,11973616,11976688,12000787,12015117,12015961,12032070,12049765,12065414,12110163,12137730,12147138,12175486,12176927,12351623,12385750,12409480,12414186,12431377,12490195,12537568,12537572,12537573,12537574,12695332,12867522,12874129,12877999,12881422,12925579,12941693,12954631,12967557,12969508,14602681,14605208,14668437,14706698,14980217,15102441,15238528,15250826,15254235,15269788,15306851,15454543,15640802,15652711,15788564,15831745,15831751,15922834,15932641,15936265,15965261,16052209,16061818,16110336,16163734,16198331,16317725,16336044,16339186,16369566,16391236,16455799,16713132,16740481,16763552,16793242,16815332,16880385,16888342,16930585,17000765,17086199,17090721,17110495,17199047,17255947,17483425,17492752,17531976,17553907,17569856,17569867,17616927,17623811,17708993,17803358,17923096,17941717,17998402,18067683,18084299,18171476,18245346,18286519,18291359,18369463,18374648,18394890,18394891,18395996,18419806,18430930,18519585,18548486,18573871,18832361,18927396,19164706,19168633,19218438,19228945,19243220,19464045,19641625,19797770,19805631,19884309,19893628,20007327,20023169,20035736,20117206,20504768,20643350,20813260,20813879,20888037,20921142,21102643,21149573,21378980,21542906,21688401,21764853,21949710,21987827,21994247,22036573,22180774,22368770,22391484,22412942,22426530,22498775,22509270,22575490,22649226,22666340,22790786,22817988,22841498,22851689,22890320,22911822,22954894,22976306,23175847,23177739,23209438,23293292,23550134,23618811,23637905,23661758,23796903,23802043,23891849,24157427,24184102,24243023,24302569,24335260,24676055,24856462,24948796,25007267,25307481,25395664,25679813,25710168,25779349,25880195,25945750	12		NP_001260844.1|MKTPVSAAANLSIQNAGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQXHLELSAGENDEEDVALETETPSNPEDPEQPMPLEFFSSASTGALELEGSASQDISLTNSELLEEESDNEQPLVLYILADDAT,NP_476586.1|MKTPVSAAANLSIQNAGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQ,NP_724882.1|MKTPVSAAANLSIQNAGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQ
136	kay	3772082		kay	AP-1|AP1|CG15507|CG15509|CG33956|D-Fos|D-fos|D-fos/kay|DFOS|DFos|DFra|DM3|DM30|Dfos|DmelCG33956|FOS|Fos|Fra|KAY|Kay|c-Fos|c-fos|d-fos|dAP-1|dFRA|dFos|dFra|dfos|dlhD|fbz|fos|fra	fruit fly	NM_001032405.4,NM_001032406.2,NM_001032407.3,NM_001032408.3,NM_001300662.1	NP_001027577.2,NP_001027578.1,NP_001027579.1,NP_001027580.1,NP_001287591.1	NT_033777.3	A0A0B4LHU8,A8MPH9,C4JC86,P21525	Nucleus.	NULL				Dm.6968	1680377,2116361,2581833,3149584,3215512,7588072,7732572,7774017,7796534,7923366,7958445,8218421,9155027,9310330,9381174,9388786,9405368,9774110,10047950,10048301,10085257,10433922,10449347,10502111,10557109,10612401,10637629,10720429,10731132,10805795,10903184,11035778,11044608,11167131,11311164,11331897,11402332,11410534,11432740,11470538,11472834,11494317,11509232,11526088,11543614,11702944,11784101,11865058,11901120,11902676,11973616,11976688,12000787,12049765,12049770,12072465,12110163,12147138,12176927,12409480,12414186,12435434,12447392,12537568,12537572,12537573,12537574,12586062,12676319,12701108,12867522,12969508,14602681,14605208,14684833,14980217,15032585,15102441,15197160,15252443,15269788,15306851,15640802,15766749,15831745,15831751,15922834,15932641,15936337,16052209,16061818,16110336,16118195,16163390,16163734,16281037,16391236,16455799,16496002,16594976,16607613,16648585,16713132,16815332,16888342,16930585,16966382,17000765,17082773,17086199,17183370,17194782,17343912,17409080,17483425,17492752,17531976,17569856,17569867,17941717,18039871,18084299,18245346,18286519,18291359,18332113,18374648,18394890,18419806,18430930,18519585,18547166,18548486,18571877,18612247,18757933,18832361,18924113,19026789,19075113,19168633,19228945,19641625,19805631,19893628,20023169,20035736,20041201,20193670,20501590,20504768,20659448,20686706,20813879,20819157,20921142,20959007,21078873,21159966,21194948,21307097,21378980,21490149,21497762,21764853,21810906,21987827,22036573,22085964,22192913,22312004,22391484,22412942,22509270,22575490,22666340,22802725,22954894,22976306,23175847,23177739,23209438,23239028,23293292,23316440,23550134,23583758,23618811,23637905,23661758,23699410,23749869,23802043,23904612,23977298,24002645,24198375,24380076,24412365,24439372,24738783,24856462,24865556,24948796,25001617,25020150,25217886,25226030,25307481,25483042,25679813,25710168,25779349,25800055,25880195,25933381,26021350,26102525	12		NP_001027577.2|MKNLNGRTHNACYHPYYHQSLHFAQQQQQQQQHHLQQQQQHMQQQQQQQQAPQQQLRHQQRQLPTQPAYQQSQSVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNNAAAMAAVCQMQNFFNQQQQQQQQLEFNNNCMPINYYQQQQQQHYPSESQSSASGWNPETPGQAQLALTATTCNTTAAATCNTTAAATTSTTATSAAAGSDNNHSDNFAMDASEIATFLANELFLQQLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL,NP_001027578.1|MTLDSYNIFNDEYLFNMPLSPLPKVLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL,NP_001027579.1|MKVKVERTTKKPAIRKPEDPDPAEEDRVKMVQDDPEDQENQAVDEEELDFLPADLSAAISTATTKIATPTRNLILGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL,NP_001027580.1|MIALKATEMQHNNNALQQQQQLQHQLLQQHQQQHQQQLQQQLNSPDNNYIWATTHNANISRNNAMLQLQQQQLRAPWITDCNKQHHINNNNSMNVNYNQQLTQQPQQQQQQTQYMQHNYNNYTQQQQQQHLVPATTSQSNSHFYQCNQQQQQQQFLAPTTTTAAVVVAAAHQQHQTQQQHQSQQQQQHQRQDYASLQMGRQLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL,NP_001287591.1|MKVKVERTTKKPAIRKPEDPDPAEEDRVKMVQDDPEDQENQAVDEEELDFLPADLSAAISTATTKIATPTRNLIVSRAETTELSGATNVQCHMTHIWVHNPFSCPPSCHLLYQMVLISVWILIPHLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL
137	foxo	41709		foxo	3143|Afx|CG3143|Dfoxo|DmQ95V5|DmelCG3143|FKHR|FOXO|FOXO1|FoxO|Foxo|Q95V55|anon-WO0118547.374|cg3143|dFOXO|dFoxO|dFoxo|dfoxo|fd88A|foxO|foxo|dFOXO	fruit fly	NM_001275628.1,NM_001316497.1,NM_142073.5,NM_206482.3,NM_206483.3	NP_001262557.1,NP_001303426.1,NP_650330.3,NP_996204.1,NP_996205.1	NT_033777.3	A0A0B4KGN1,Q95V55	Cytoplasm.  Nucleus.	NULL				Dm.3957	10731132,12537568,12537572,12537573,12537574,12844367,12893776,12908874,14563554,14605208,14745961,14764878,15175753,15192154,15545659,15565107,15589139,15704171,15710747,15734678,15734679,15734681,15820683,15843412,15851659,15935772,15963974,15998720,16054033,16055649,16086608,16103212,16110336,16163709,16179433,16230533,16243018,16254176,16271526,16332201,16520939,16564014,16774996,16783380,16785324,16890541,16938867,17055976,17090700,17113379,17139322,17167488,17183370,17208179,17215387,17234883,17363962,17369395,17369827,17462592,17462750,17465980,17569856,17569867,17603113,17686972,17705839,17765686,17895391,18068153,18177722,18221413,18234213,18241326,18245346,18245854,18246068,18299344,18344986,18396138,18460334,18562277,18632097,18650956,18665908,18687152,18690062,18815370,18827008,19005568,19018274,19043547,19128792,19141596,19211682,19214224,19237508,19317915,19378453,19378454,19390610,19406101,19470468,19477978,19494035,19543366,19553463,19594484,19627268,19651894,19684592,19692410,19696884,19720829,19727075,19804760,19822665,19840842,19855018,19861550,19910925,20005803,20059956,20080168,20090753,20117129,20195385,20203043,20333234,20339377,20346676,20417156,20478298,20496123,20498635,20504961,20585550,20585652,20624856,20627082,20634900,20655917,20686706,20688956,20734804,20739318,20816975,20849947,20888228,20940226,20976250,21035763,21036383,21040900,21078113,21108726,21111239,21145317,21149573,21195352,21217822,21234801,21346761,21372148,21406223,21443682,21512585,21518241,21565616,21635778,21664581,21669932,21680868,21694719,21814033,21816278,22053049,22068330,22102829,22117545,22134547,22156377,22242005,22275878,22312004,22326868,22378780,22384357,22393355,22493059,22493273,22510984,22513101,22518146,22529821,22570625,22654869,22672579,22724070,22751499,22786647,22843669,22851689,22858408,22876196,22911822,22913798,22935001,22949833,22956542,22997544,23063786,23121290,23129806,23236133,23240086,23246004,23251396,23307869,23355844,23499946,23519314,23593018,23608455,23624434,23649823,23818862,23853709,23874700,23878722,23885240,23895933,23934892,23936253,23977298,24035390,24038661,24062693,24069139,24092876,24133012,24133450,24137131,24149429,24191061,24244197,24335260,24348428,24357229,24380076,24430872,24439372,24508462,24508822,24509725,24513978,24558258,24603715,24609035,24685228,24690889,24705759,24746817,24755363,24768030,24778227,24819984,24821805,24832605,24847072,24883306,24902837,24916379,24949430,24981286,24983497,24993942,25007267,25043021,25126791,25133314,25217886,25223702,25232726,25280996,25329053,25356674,25421296,25421701,25511696,25520354,25663303,25740230,25814322,25824290,25920570,25959206,26119340,26474173,26553999,26606805	12		NP_001262557.1|MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEDNNCASTLIGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH,NP_001303426.1|MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGSYGWSRFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH,NP_650330.3|MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEDNNCASTLIGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH,NP_996204.1|MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH,NP_996205.1|MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH
138	Ilp2	39150		Ilp2	CG8167|DILP|DILP-2|DILP2|Dilp|Dilp 2|Dilp-2|Dilp2|DmelCG8167|ILP2|IRP|Ilp|Ilp-2|dILP-2|dILP2|dIlp2|dilp|dilp-2|dilp2|ilp2	fruit fly	NM_079288.3	NP_524012.1	NT_037436.4	E7BBS1,Q9VT51	Secreted.	NULL				Dm.2285	10731132,11179818,11250149,11301264,11396725,11782950,11897402,12004130,12176357,12427481,12537568,12537572,12537573,12537574,12559758,12618402,12852852,14505564,14505573,14738879,15175753,15592467,15708981,15820683,16099985,16110336,16122349,16150727,16163709,16172603,16187303,16243018,16332201,16481470,16870731,16890541,17139322,17465980,17569856,17569867,17686972,17707655,18056636,18084299,18177722,18221413,18344986,18365028,18396138,18396139,18412985,18434551,18460334,18628395,18634898,18665908,18690062,18803813,18852455,18972134,19005568,19128792,19136634,19319573,19352497,19378453,19378454,19385039,19390610,19459219,19470468,19494137,19594484,19619547,19627268,19680544,19723496,19757495,19840842,19887630,19914231,20001959,20044986,20059956,20059957,20074523,20107057,20117129,20156206,20195385,20195512,20223202,20333234,20417156,20444422,20447440,20493190,20585652,20627082,20628603,20652954,20699643,20739318,20849947,20890228,20926386,21035763,21108726,21111239,21159815,21183078,21195352,21196470,21209905,21303840,21346761,21406223,21443682,21565616,21572965,21664581,21719444,21814033,21816278,21818550,21850269,21901108,22036568,22036573,22053049,22116763,22173880,22228302,22367393,22385966,22407365,22411915,22654869,22685490,22778134,22792260,22829591,22876196,22935001,22960233,23021220,23077061,23121290,23129806,23150601,23251396,23307869,23326371,23407678,23471909,23477723,23587196,23591813,23608455,23760890,23853709,23866071,23874700,23885240,24006466,24035390,24062693,24094110,24133450,24137131,24192838,24240321,24278035,24348428,24357229,24385933,24430872,24439370,24439378,24489769,24495972,24505416,24508822,24558258,24609035,24651653,24685228,24690889,24755363,24766812,24768030,24795642,24821805,24845618,24861087,24864304,24902837,24937262,24949430,25015062,25064813,25101872,25126791,25200291,25203426,25356674,25393288,25393614,25451929,25452710,25481758,25523082,25541690,25565944,25566191,25651184,25821834,25850671,25850672,25882208,25994086,26138755	12		NP_524012.1|MSKPLSFISMVAVILLASSTVKLAQGTLCSEKLNEVLSMVCEEYNPVIPHKRAMPGADSDLDALNPLQFVQEFEEEDNSISEPLRSALFPGSYLGGVLNSLAEVRRRTRQRQGIVERCCKKSCDMKALREYCSVVRN
139	IRGM	345611	Immunity-related GTPase family M protein	IRGM	IFI1|IRGM1|LRG-47|LRG47	human	NM_001145805.1,XM_011537641.1,XR_944324.1	NP_001139277.1,XP_011535943.1	NC_000005.10,NC_018916.2,NG_027809.1,NT_029289.12,NW_004929324.1	A1A4Y4	Golgi apparatus membrane.  Cellmembrane.  Cytoplasmic vesicle, phagosome membrane.	NULL			Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity). {ECO:0000250, ECO:0000269|PubMed:16888103}.	Hs.519680,Hs.652148	7561525,12477932,14576437,16277747,16888103,17554261,17554300,17921695,18438406,18580884,18587394,18936107,18985712,19098858,19120485,19165925,19174780,19266026,19422935,19491842,19683022,19750224,19760754,20024904,20106866,20210993,20360734,20395867,20547146,20737271,20886065,20962850,21049557,21072187,21079743,21102437,21102463,21283700,21508684,21981022,22163006,22174682,22228152,22370477,22508677,22573572,22713085,23049477,23128233,23365659,24232856,24264476,24469081,24595493,24626347,24656308,24713404,24859836,25191865,25526194,25619828,25707354,25853521,25891078	15		NP_001139277.1|MEAMNVEKASADGNLPEVISNIKETLKIVSRTPVNITMAGDSGNGMSTFISALRNTGHEGKASPPTELVKATQRCASYFSSHFSNVVLWDLPGTGSATTTLENYLMEMQFNRYDFIMVASAQFSMNHVMLAKTAEDMGKKFYIVWTKLDMDLSTGALPEVQLLQIRENVLENLQKERVCEY,XP_011535943.1|MEAMNVEKASADGNLPEVISNIKETLKIVSRTPVNITMAGDSGNGMSTFISALRNTGHEGKASPPTELVKATQRCASYFSSHFSNVVLWDLPGTGSATTTLENYLMEMQFNRYDFIMVASAQFSMNHVMLAKTAEDMGKKFYIVWTKLDMDLSTGALPEVQLLQIRENVLENLQKERLACHEKYLKSTPENSTRPRNIPSRRKLYVNLLRIFNS
140	NOD1	10392		NOD1	CARD4|CLR7.1|NLRC1	human	NM_006092.2,XM_005249568.1,XM_005249572.1,XM_005249576.1,XM_006715633.2,XM_011515079.1,XM_011515080.1,XM_011515081.1,XM_011515082.1,XM_011515083.1,XM_	NP_006083.1,XP_005249625.1,XP_005249629.1,XP_005249633.1,XP_006715696.1,XP_011513381.1,XP_011513382.1,XP_011513383.1,XP_011513384.1,XP_011513385.1,XP_	NC_000007.14,NC_018918.2,NG_013025.1,NT_007819.18,NW_004929329.1	A0A024RA73,G3XAL1,Q9Y239	Cytoplasm.  Cell membrane.  Apical cellmembrane.  Basolateral cell membrane.	NULL				Hs.405153,Hs.738731	10224040,10329646,10880512,11058605,11113115,12459189,12477932,12690205,12761501,12775719,12791997,12813035,12853948,12871942,14702039,14977954,15107016,15276183,15489334,15653568,15657077,15718249,15790594,15967716,15990792,16083881,16115863,16172124,16260731,16446438,16464805,16493424,16517750,16741608,16893397,16918516,16935475,17005562,17012967,17030188,17054981,17100974,17156193,17285593,17309748,17322292,17337451,17403538,17420470,17435760,17452051,17521327,17595233,17613538,17620097,17907287,17964870,17970764,18186648,18397186,18426885,18521924,18536738,18573991,18574154,19043560,19050632,19074885,19120480,19122645,19167431,19247692,19260860,19264973,19273470,19327158,19337385,19401779,19406482,19423540,19538217,19570976,19587002,19660916,19667203,19723304,19818630,19843337,19882212,19898471,19913121,20002790,20007577,20039881,20124104,20300534,20384614,20389019,20395963,20403997,20406964,20438785,20453000,20470879,20485444,20519512,20595247,20628086,20646321,20713621,20818820,20844241,20846183,21042538,21048031,21097508,21241317,21263023,21310790,21330608,21342182,21677137,21722177,21739538,21745515,21757725,21768114,21864388,21924184,21978001,21988832,22062585,22143988,22218461,22507623,22563200,22658674,22763410,22795647,22848741,22870324,22902391,23062636,23107019,23136938,23182460,23275338,23300079,23353647,23382681,23460743,23711367,23712977,23740944,23839082,23888881,23901396,23935490,24018334,24041848,24053487,24143223,24295830,24366254,24444388,24598002,24661094,24690886,24746552,24829218,24832447,24934088,24958724,25012219,25024364,25036637,25093298,25503380,25801093,25840495,25854006,25891078,25933107,26052894,26871637	15		NP_006083.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_005249625.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_005249629.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_005249633.1|MSRDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_006715696.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_011513381.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_011513382.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_011513383.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_011513384.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_011513385.1|MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF,XP_|
141	NOD2	64127	Nucleotide-binding oligomerization domain-containing protein 2	NOD2	ACUG|BLAU|CARD15|CD|CLR16.3|IBD1|NLRC2|NOD2B|PSORAS1	human	NM_001293557.1,NM_022162.2,XM_005256084.2,XM_006721242.2,XM_006721243.2,XM_011523257.1,XM_011523258.1,XM_011523259.1,XM_011523260.1,XM_011523261.1,XR_	NP_001280486.1,NP_071445.1,XP_005256141.1,XP_006721305.1,XP_006721306.1,XP_011521559.1,XP_011521560.1,XP_011521561.1,XP_011521562.1,XP_011521563.1	NC_000016.10,NC_018927.2,NG_007508.1,NT_010498.16,NW_004929402.1	Q9HC29	Cytoplasm.  Membrane.  Basolateral cell membrane.	NULL			Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561). {ECO:0000269|PubMed:18511561, ECO:0000269|PubMed:23806334}.	Hs.592072	7809109,8587604,8894707,9541106,9797359,9924607,10053016,10439963,11087742,11318544,11385576,11385577,11425413,11472070,11528384,11752413,11834373,11837220,11875755,11890351,11910336,11910337,11938034,11976792,12019209,12019468,12020527,12105836,12105838,12115195,12115249,12198692,12202985,12210321,12360101,12397216,12415614,12454871,12459523,12474146,12492195,12508397,12512038,12512064,12514169,12527755,12529700,12532667,12556233,12563685,12577202,12595627,12595906,12617879,12618963,12626759,12631666,12631668,12631669,12649405,12650796,12671896,12671897,12673278,12704363,12810925,12823148,12851870,12871942,12876263,12879366,12923865,12930309,12940436,13680285,14508222,14516815,14522785,14555911,14597055,14627676,14638352,14644139,14690304,14743885,14747834,14750643,14971813,14996717,15002819,15008984,15016407,15024686,15044951,15046221,15046222,15052696,15056084,15075345,15090455,15095853,15107016,15107849,15140210,15142196,15145460,15168811,15180737,15190267,15194649,15202784,15214053,15276183,15279649,15289769,15308523,15320482,15367194,15377357,15459013,15468360,15472511,15479689,15489579,15492242,15515785,15516360,15520108,15527324,15539411,15539413,15551253,15571586,15571588,15578724,15620648,15626887,15626888,15637755,15638227,15643611,15653568,15654786,15655821,15666202,15667501,15685536,15712650,15753091,15770725,15778542,15785318,15795594,15800781,15803022,15807862,15812565,15840263,15842589,15843082,15927452,15930978,15967635,15967716,15973116,15973118,15984988,15990626,15998797,16000642,16002353,16008671,16009674,16010583,16080653,16115863,16126943,16133971,16134725,16134731,16148063,16161956,16167972,16174099,16179784,16198136,16203728,16230083,16239840,16239841,16244543,16255050,16257953,16260731,16266221,16267612,16278823,16279904,16306764,16315780,16319062,16344053,16344054,16385250,16389181,16393227,16397396,16402184,16414084,16416181,16424393,16436969,16437636,16437728,16441470,16446977,16454837,16461743,16485124,16489646,16492792,16493424,16493449,16494109,16494592,16510569,16519819,16522788,16534418,16611251,16614992,16641610,16642031,16669960,16670523,16670524,16714539,16716969,16741608,16771961,16773683,16804398,16804670,16819374,16825909,16840031,16897777,16907704,16920047,16933467,16949315,16952484,16965521,16977346,17005562,17006998,17009307,17012967,17018387,17020469,17030188,17057186,17058067,17068223,17096091,17100974,17100976,17101573,17113749,17119385,17131470,17142621,17156146,17156193,17157607,17160430,17171451,17174426,17187069,17200669,17206080,17206636,17206688,17258734,17269998,17278126,17285593,17301648,17303577,17319929,17333217,17337451,17337463,17348859,17351900,17355968,17356065,17379562,17389014,17389035,17393391,17403538,17404888,17417801,17420470,17435756,17447842,17451203,17452051,17460484,17476680,17484863,17484864,17486745,17489054,17498224,17509030,17538984,17548659,17554300,17558494,17558906,17563761,17565648,17570063,17595233,17600378,17613538,17620097,17652449,17660460,17661913,17666747,17684544,17690884,17703412,17705850,17719742,17724347,17725592,17763471,17786191,17804789,17852840,17876878,17877509,17892524,17894849,17907287,17911997,17919942,17941079,17964196,17964870,17965022,17968944,17976376,17978873,17980027,18022867,18022871,18028374,18047543,18052659,18069758,18088053,18090989,18092344,18092345,18096043,18157816,18158963,18162085,18166373,18182678,18184136,18200509,18200510,18213697,18219096,18227809,18240302,18243161,18248772,18253730,18256385,18271063,18305068,18317454,18329614,18340358,18341489,18367950,18371139,18371140,18382655,18383179,18384487,18413660,18419343,18433468,18438406,18466472,18489434,18507017,18521914,18521924,18541930,18563169,18573991,18574154,18576390,18587394,18594982,18617779,18619921,18633131,18640012,18647548,18670786,18676680,18680223,18698678,18715515,18756601,18758419,18758464,18787464,18804983,18818748,18819462,18824555,18855982,18938111,18942751,18942754,18972554,18976442,18985712,19019335,19050632,19058231,19074885,19079230,19098858,19103524,19103559,19112191,19116920,19120480,19139201,19169908,19170196,19174806,19183163,19184348,19184350,19189651,19200604,19219079,19235913,19240061,19244164,19247692,19253375,19258923,19262523,19266573,19273470,19275920,19299732,19305026,19319132,19337309,19337385,19349988,19397946,19406482,19422935,19423540,19426395,19434699,19479836,19479837,19482182,19527514,19535145,19570052,19570976,19572373,19579027,19579029,19590455,19592251,19625176,19638967,19641059,19659808,19664207,19667203,19679065,19679608,19692168,19693669,19701189,19701969,19713276,19721713,19728064,19748964,19759286,19760754,19787357,19809335,19822951,19826411,19830732,19843337,19853919,19880660,19888426,19896081,19898471,19907652,19912254,19913121,19948723,19966812,20002790,20018961,20024904,20027650,20032092,20047977,20066736,20079790,20082483,20087966,20110711,20124104,20140262,20155851,20177049,20182871,20230816,20232407,20298285,20332463,20346235,20350193,20362271,20371648,20373538,20379614,20380008,20384614,20385562,20387682,20403997,20406964,20412372,20428899,20436512,20438785,20441518,20452482,20453000,20483763,20485703,20503287,20524760,20525885,20537165,20541026,20549515,20565245,20570966,20583427,20595247,20601676,20622911,20628086,20632099,20637199,20646002,20646321,20673868,20676658,20698950,20713205,20800603,20839241,20844241,20850627,20854823,20865702,20875485,20886065,20940596,20959815,20962850,21039068,21040192,21040358,21042538,21097508,21102463,21123652,21155887,21172192,21206965,21209938,21215810,21218092,21241317,21263023,21274544,21310790,21335489,21337670,21342182,21343918,21385537,21388357,21391291,21410503,21448648,21460759,21565239,21573891,21596301,21625457,21659536,21665963,21690088,21699783,21716313,21730793,21734346,21734790,21739538,21744420,21745302,21745515,21768114,21799103,21887730,21914217,21943069,21978001,22139875,22147245,22212192,22218461,22244368,22266421,22275320,22286692,22289211,22319155,22346247,22397822,22412388,22416979,22426692,22464675,22502597,22504414,22509093,22549783,22563200,22571967,22605977,22607974,22665475,22684479,22700971,22719818,22730064,22739221,22795647,22807259,22815893,22829933,22879519,22936669,22997500,22998942,23019338,23085276,23100559,23102769,23109427,23121969,23128233,23173613,23287275,23300079,23322906,23376921,23409731,23437331,23488593,23493074,23558906,23562557,23594678,23615072,23651603,23709157,23711367,23712977,23740944,23806334,23818254,23824692,23850724,23868940,23872065,23888881,23892590,23901396,23977330,23991106,24015287,24018334,24047397,24054330,24076061,24098051,24099766,24295830,24297055,24298015,24345423,24360029,24366254,24391456,24393249,24444388,24586700,24597572,24627602,24651958,24656308,24670424,24671169,24679666,24682985,24695226,24719038,24722226,24781050,24782627,24790089,24803813,24832447,24901824,24932916,24960071,25024364,25042478,25048429,25053139,25093298,25148897,25170077,25171511,25183734,25248089,25259511,25326182,25335775,25365249,25367361,25549945,25642632,25649363,25664710,25670499,25674246,25722298,25801769,25825396,25840495,25891078,25910289,25922834,25933107,26019273,26042516,26070941,26147989,26167078,26517420,26670046	15		NP_001280486.1|MCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,NP_071445.1|MGEEGGSASHDEEERASVLLGHSPGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,XP_005256141.1|MCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,XP_006721305.1|MCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,XP_006721306.1|MCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKAL,XP_011521559.1|MDWLPSFYNMFRNYQSHWPCLWKMRELRPRKAKWLAQVYGGPRFSNSAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,XP_011521560.1|MDWLPSFYNMFRNYQSHWPCLWKMRELRPRKAKWLAQVYGGPRFSNSAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,XP_011521561.1|MAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRGNTFSLEEVDKLGCRDTRLLL,XP_011521562.1|MCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKAL,XP_011521563.1|MCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKAL
142	HDAC6	10013		HDAC6	CPBHM|HD6|JM21|PPP1R90	human	NM_001321225.1,NM_001321226.1,NM_001321227.1,NM_001321228.1,NM_001321229.1,NM_001321230.1,NM_001321231.1,NM_006044.3,NR_135591.1,NR_135592.1,NR_135593	NP_001308154.1,NP_001308155.1,NP_001308156.1,NP_001308157.1,NP_001308158.1,NP_001308159.1,NP_001308160.1,NP_006035.2,XP_005272621.2,XP_005272622.1,XP_	NC_000023.11,NC_018934.2,NG_012560.1,NT_079573.5,NW_004929439.1	A0A024QZ26,B4DZH6,Q9UBN7	Nucleus.  Cytoplasm.  Perikaryon.  Cell projection, dendrite.  Cellprojection, axon.	NULL				Hs.6764	9139815,9150131,10048485,10220385,10898795,11474198,11533236,11677242,11689694,11861901,11948178,12024216,12032081,12354939,12391164,12477932,12486003,12535528,12606581,12620231,12718889,12792815,14670976,14675537,14702039,14743216,15102857,15171253,15302935,15347674,15467736,15469820,15501975,15806142,15831498,15831516,15835920,15916966,15937109,15937340,15976449,16082198,16148047,16186112,16192271,16288017,16344560,16738306,16919237,16951198,16964243,17389687,17474147,17512543,17516032,17588522,17604723,17643370,17785525,17846173,17851643,17872950,18029348,18079183,18316616,18356165,18413721,18499657,18568448,18591380,18606987,18636984,18644987,18671804,18697214,18781140,18794144,18852123,18996840,19033385,19036992,19081074,19158084,19167333,19228685,19321449,19344692,19383825,19438744,19596000,19737819,19744931,19805354,19855091,19893491,19910924,19913121,19961433,20008322,20018896,20029029,20102703,20129057,20133936,20159555,20181727,20308065,20360068,20371724,20457763,20593489,20628086,20696758,20720006,20837465,20970878,21044318,21076528,21082217,21090589,21103663,21220424,21235576,21284752,21340680,21377170,21421902,21455583,21486957,21532619,21562571,21690293,21699378,21753002,21847094,21847364,21900206,21949397,21952047,21988832,22022450,22069321,22089141,22124372,22174839,22193721,22238643,22334690,22367689,22367781,22372633,22375943,22384180,22392728,22464548,22492994,22504143,22589388,22645275,22658674,22674379,22678362,22766642,22778253,22792322,22797925,22936009,22952844,22955928,22957056,22967444,22989952,22994762,23010497,23076141,23084749,23133622,23152903,23159615,23181831,23258539,23322205,23370327,23402884,23405166,23487739,23580651,23618908,23621219,23634874,23698468,23703321,23723075,23727580,23752268,23770849,23798680,23824909,23962722,23974956,24023063,24025866,24035499,24086678,24089523,24146251,24200693,24216476,24220335,24255178,24302573,24308962,24413532,24474193,24474778,24561123,24574519,24614595,24618845,24658140,24685680,24687993,24722339,24795145,24861260,24882211,24932665,25031336,25070956,25111897,25299772,25307283,25342804,25402006,25429107,25482939,25516595,25548531,25609649,25770209,25774669,25921289,25946558,25963833,26080397,26105074,26112604,26112958,26150340,26186194,26210454,26227334,26363065,26471297,26496610,26508657,26524593,26549023,26673895	15		NP_001308154.1|MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,NP_001308155.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,NP_001308156.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,NP_001308157.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,NP_001308158.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,NP_001308159.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHR,NP_001308160.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHR,NP_006035.2|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,XP_005272621.2|MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,XP_005272622.1|MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH,XP_|
143	WDFY3	23001		WDFY3	ALFY|ZFYVE25	human	NM_014991.4,NM_178583.2,NM_178585.2,XM_005262858.3,XM_011531757.1,XM_011531758.1,XM_011531759.1,XM_011531760.1,XM_011531761.1,XM_011531762.1,XM_011531	NP_055806.2,XP_005262915.1,XP_011530059.1,XP_011530060.1,XP_011530061.1,XP_011530062.1,XP_011530063.1,XP_011530064.1,XP_011530065.1,XP_011530066.1,XP_	NC_000004.12,NC_018915.2,NG_046917.1,NT_016354.20,NW_004929320.1	A0A024RDI0,Q8IZQ1	Nucleus membrane.  Cytoplasm.  Nucleus, PMLbody.  Membrane.	NULL				Hs.480116,Hs.726339	8619474,8889548,9110174,9847074,10231032,12168954,12477932,14702039,15292400,15489334,17207965,17452356,18083104,20168092,20379614,20417604,20493804,20971078,21150266,21516116,22458338,22658674,23455922,23455924,23640897,23824909,24128730,24668264,25416956,25814554,26186194,26496610	15		NP_055806.2|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_005262915.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530059.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530060.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530061.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530062.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530063.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530064.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVAKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530065.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_011530066.1|MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEKQCALLSPKDFKATTPSEAASRAIVQFLEINQSEEASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKPAGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQPFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFDRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEAGLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPHDIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAIVLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSKGMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEASKNAKLMREFQLIPKLLLTLRDMSLSQPTIAAISNVLSFLLQGFPSSNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVISCRSKQGCQFDLDSIWTFIFGVPASSGTVVSSIHNVCTEAVFLLLGMLRSMLTSPWQSEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCNVGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSRAHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEGRQLLIKAVNRVWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEKKCISRGEALAPTTQSKLSRVSSGFGLSKLTGSRRNRKESGLNKHSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEYYMRLASGNPAIVQDAIVESSEGEAAQQEPEHGEDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSIEEEEKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCSIFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLTDSSESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEKAKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC,XP_|
144	MAPK8	5599		MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	human	NM_001278547.1,NM_001278548.1,NM_001323302.1,NM_001323320.1,NM_001323321.1,NM_001323322.1,NM_001323323.1,NM_001323324.1,NM_001323325.1,NM_001323326.1,	NP_001265476.1,NP_001265477.1,NP_001310231.1,NP_001310249.1,NP_001310250.1,NP_001310251.1,NP_001310252.1,NP_001310253.1,NP_001310254.1,NP_001310255.1,	NC_000010.11,NC_018921.2,NG_029053.2,NT_030059.14,NW_004929376.1	A1L4K2,P45983	Cytoplasm. Nucleus.	NULL				Hs.138211,Hs.522924	1748630,7535770,7642542,7737129,7737130,7839144,8001819,8137421,8177321,8224842,8586671,8621542,8632909,8654373,8846788,8917518,9020136,9030579,9045910,9129988,9162092,9195981,9199329,9199504,9207092,9211903,9223324,9235954,9343414,9374537,9393873,9396779,9399639,9403476,9405400,9405416,9520479,9575168,9621077,9661668,9670954,9692890,9724739,9732264,9733513,9774977,9788880,9808624,9851932,9872331,9889198,10187783,10346818,10357815,10383391,10391943,10393177,10394361,10419510,10446219,10471813,10490659,10509564,10521505,10523642,10551811,10567572,10585392,10597297,10601313,10629060,10713157,10722755,10747973,10756100,10797012,10799874,10856240,10878576,10912793,10913135,10962563,11042694,11057897,11062067,11108663,11153078,11238452,11260070,11278389,11278395,11278789,11278799,11279118,11279197,11279232,11283254,11323415,11350938,11387337,11408587,11432831,11448159,11468147,11479302,11489891,11504923,11517249,11525649,11551945,11566021,11602244,11606564,11698270,11700324,11707464,11749722,11781324,11788583,11865055,11907583,11912216,11931768,11944898,11948398,11971973,11983683,11988087,12023963,12039864,12052834,12058026,12058028,12079429,12089333,12095152,12097334,12121974,12135322,12138158,12140754,12143039,12148599,12167088,12171600,12185592,12189133,12206715,12225289,12228228,12239168,12242293,12296995,12351658,12351702,12354774,12359245,12376548,12391307,12413764,12417588,12421945,12477932,12478662,12514174,12538493,12576423,12591950,12592382,12646240,12646564,12659851,12689591,12697749,12707267,12714584,12734330,12756254,12763138,12775419,12787561,12788955,12804775,12810082,12818176,12821118,12847227,12853963,12857973,12859962,12874243,12878610,12902351,12917434,12958075,12960231,12963725,13130464,14500675,14500727,14504284,14514687,14517282,14532003,14551213,14557276,14561739,14572659,14597672,14612408,14615289,14633987,14637155,14688370,14699155,14701702,14701799,14702039,14724588,14729602,14764673,14766760,14967141,14981905,15013949,15184502,15225643,15238629,15246824,15276183,15299005,15302935,15326485,15334056,15345747,15383283,15456887,15474087,15483136,15516492,15527495,15528994,15538975,15542843,15569856,15590691,15603708,15629131,15637062,15655348,15657352,15659383,15665513,15677475,15688026,15693750,15696159,15721744,15722200,15733859,15749833,15755722,15769735,15778365,15778501,15827086,15850461,15857981,15860507,15890690,15894542,15958389,15979846,15981086,15998799,16007099,16038800,16086581,16105650,16153436,16157600,16166642,16176806,16243842,16260419,16260609,16264271,16282329,16283431,16291755,16307741,16321971,16328781,16339571,16343492,16344560,16381010,16395283,16407310,16412424,16434970,16446428,16465391,16481105,16533805,16539678,16549498,16569638,16581800,16611996,16636664,16648634,16687404,16699726,16740711,16760468,16794185,16802349,16810318,16814421,16815888,16824735,16840345,16895791,16912864,16927023,16972261,16982329,16983342,17008315,17023523,17054907,17074809,17079291,17145805,17158878,17178870,17189706,17192257,17255354,17296730,17303384,17317777,17363973,17453826,17478078,17481915,17496921,17541429,17545598,17568996,17584736,17603935,17620321,17626013,17640761,17652454,17690186,17693927,17699782,17702750,17703233,17704768,17719653,17785464,17875713,17883418,17904874,17908987,17913539,17933493,17942603,17967471,17982228,18003900,18025271,18036196,18055217,18082745,18086557,18087676,18094581,18160848,18164704,18181766,18199680,18212053,18218857,18219313,18249102,18253836,18256527,18276794,18286207,18288129,18292600,18293403,18297686,18316600,18316603,18325654,18337589,18344085,18348163,18356158,18373696,18387958,18401423,18405916,18429822,18439101,18457359,18495129,18506470,18524773,18540881,18541008,18547751,18570871,18573678,18594007,18603327,18620777,18636174,18651223,18663379,18667537,18681908,18682391,18703151,18713649,18713996,18718914,18723442,18757369,18769111,18782768,18813780,18815275,18818208,18845538,18922473,18936517,18950845,18957422,18978303,18979912,18982452,18989785,18996088,19033664,19036714,19037093,19041150,19052872,19056926,19060920,19069644,19071215,19074436,19097143,19153595,19154785,19159663,19166930,19168796,19194824,19204086,19206162,19234442,19245816,19248119,19270716,19275580,19286999,19287189,19319745,19339050,19351724,19352384,19418584,19424800,19454725,19468799,19478459,19479051,19523467,19527717,19567513,19570911,19574423,19589256,19593445,19596001,19604147,19616043,19620725,19638579,19651615,19664626,19667122,19676104,19686584,19690982,19693773,19695707,19723092,19723627,19748889,19778898,19782079,19801633,19802005,19803394,19806201,19815509,19822148,19822666,19843478,19859790,19862774,19864026,19877043,19893453,19900593,19901160,19910486,19913121,19923798,19937141,19940138,19940360,19966288,19995557,19996270,20018857,20027304,20051532,20056178,20056910,20060003,20069553,20070836,20070945,20074375,20086174,20088952,20102411,20103647,20116378,20130137,20133937,20138424,20139358,20142324,20145041,20150185,20156194,20173753,20186153,20194509,20225236,20336759,20371626,20380698,20432452,20450729,20452983,20457808,20483637,20483734,20490718,20495362,20510162,20511226,20512919,20512932,20525557,20551953,20566643,20573157,20581839,20622336,20628086,20632440,20647313,20648623,20680486,20717968,20732415,20735357,20829350,20870032,20878914,20919940,20944115,20960177,21095239,21106355,21122381,21123173,21134350,21145111,21148294,21148313,21152872,21156789,21172010,21172429,21187925,21191018,21212517,21223552,21237154,21362231,21364631,21364637,21368226,21378396,21384452,21439937,21444723,21454558,21465527,21483469,21483669,21504622,21511059,21524306,21526344,21629969,21651489,21660049,21697181,21719561,21729547,21752354,21757743,21764057,21768777,21775054,21806545,21817106,21822690,21832049,21856198,21863240,21900206,21931671,21943220,21948112,21959987,21964465,21984578,21988832,22005259,22014979,22021110,22027397,22065586,22087220,22100391,22110360,22114267,22154358,22164242,22171160,22184250,22283740,22327296,22351776,22357202,22363806,22394200,22433870,22435755,22441692,22446103,22447977,22450687,22456510,22493283,22493490,22506718,22509080,22689214,22729748,22749438,22763043,22766602,22844345,22850273,22870247,22902540,22920299,22942770,23020677,23051914,23056263,23077074,23237571,23258237,23273084,23290789,23326144,23359252,23393199,23397142,23416355,23440494,23555914,23580093,23602568,23603344,23608488,23608534,23615449,23662689,23712703,23715767,23762317,23770673,23776175,23799149,23816567,23817665,23857473,23861391,23863879,23891538,23900581,23900681,23906792,23912840,23916702,23922701,23981301,24008433,24023255,24023291,24037431,24040019,24044867,24055030,24073601,24086554,24091673,24127566,24170769,24184208,24225136,24316756,24335928,24366007,24418364,24434780,24452601,24457963,24502975,24515257,24515990,24556843,24587347,24589734,24642040,24658140,24661418,24679696,24699410,24704364,24787013,24820448,24825906,24862326,24874739,24901053,24906853,24914133,24927726,24936061,24947996,24963148,24970676,24975362,24984152,25043814,25064159,25068797,25077544,25113506,25116390,25143627,25160932,25164676,25218495,25233933,25241761,25254627,25270024,25284480,25288801,25316285,25341038,25353341,25398907,25402006,25415535,25423287,25456131,25496033,25501809,25502879,25504636,25526895,25546243,25583514,25642820,25726846,25737554,25779847,25792289,25847947,25852190,25896662,25943894,25955534,26095851,26157010,26186194,26296767,26344197,26352010,26496610,26519559,26546165	15		NP_001265476.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR,NP_001265477.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ,NP_001310231.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ,NP_001310249.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR,NP_001310250.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ,NP_001310251.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR,NP_001310252.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR,NP_001310253.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ,NP_001310254.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ,NP_001310255.1|MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ
145	AVO1	854076	Target of rapamycin complex 2 subunit AVO1			baker's yeast	NM_001183332.1	NP_014563.1	NC_001147.6	Q08236	Cell membrane.	NULL			Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway.		8849441,9169874,11805826,11805837,12408816,12631735,14736892,15809876,16002396,16155567,16319894,17303383,18552287,18667435,19144819,19269370,19840948,19841731,20101242,20489023,21035341,22207764,22505404,23332755,24386330,26028537,26493364,26700129	28		NP_014563.1|MDTVTVLNELRAQFLRVCPEKDQMKRIIKPYIPVDEFNTEQCLDSSIRELYMNSDGVSLLPELESPPVSKDFMENYASLGKMRIMRENEGQKGKANQNLIGAEKTERDEEETRNLQDKSAKNTLIVEENGTLRYNPLNSSASNSLLNDDDHTSGKHHKTSSKEDSYLNSSMEMQKKSSKRSSLPFVRIFKSRRDHSNTSGNKNVMNTTNTRAKSSTLHPPGARHNKKGSKFDMNFDFDENLEEEDDDDDDDEEGDDIHSQFFQLDDDFDAKGSGASPAHKGINGMSNNKNNTYTNNRNSISILDDRESSNGNIGSASRLKSHFPTSQKGKIFLTDNKNDGQKSDSLNANKGIHGDGSSASGNGSVSRDGLTETESNNISDMESYINEKDLDDLNFDTVTSNINKTVSDLGGHESTNDGTAVMNRDSKDSRSNSNEFNAQNRDRITPGSSYGKSLLGSEYSEERYSNNDSSTMESGEMSLDSDMQTNTIPSHSIPMSMQKYGIYHGDDDSTLNNVFDKAVLTMNSSRHPKERRDTVISGKEPTSLTSSNRKFSVSSNLTSTRSPLLRGHGRTSSTASSEHMKAPKVSDSVLHRARKSTLTLKQDHSQPSVPSSVHKSSKEGNILIEKTTDYLVSKPKASQLSNMFNKKKKRTNTNSVDVLEYFSFVCGDKVPNYESMGLEIYIQASKKYKRNSFTTKVRKSSTIFEVIGFALFLYSTEKKPDNFEEDGLTVEDISNPNNFSLKIVDEDGEPFEDNFGKLDRKSTIQSISDSEVVLCKVDDAEKSQNEIETPLPFETGGGLMDASTLDANSSHDTTDGTINQLSFYKPIIGNEDDIDKTNGSKIIDVTVYLYPNVNPKFNYTTISVLVTSHINDILVKYCKMKNMDPNEYALKVLGKNYILDLNDTVLRLDGINKVELISKKDARELHLEKMKPDLKKPVLPTIQSNDLTPLTLEPLNSYLKADAGGAVAAIPENTKVTSKAKKISTKYKLGLAKQHSSSSVASGSVSTAGGLANGNGFFKNKNSSKSSLHGTLQFHNINRSQSTMEHTPDTPNGVGDNFQDLFTGAYHKYKVWRRQQMSFINKHERTLAIDGDYIYIVPPEGRIHWHDNVKTKSLHISQVVLVKKSKRVPEHFKIFVRREGQDDIKRYYFEAVSGQECTEIVTRLQNLLSAYRMNHK
146	AVO2	855090	Target of rapamycin complex 2 subunit AVO2			baker's yeast	NM_001182566.1	NP_013784.1	NC_001145.3	Q04749	Cell membrane.	NULL			Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway.		8849441,9169872,10688190,11283351,11914276,12408816,12631735,14736892,15372071,15689497,15809876,16002396,16319894,16554755,17507646,18087042,18552287,19269370,20093466,20489023,21035341,21460040,21552543,22207764,23332755,26028537	28		NP_013784.1|MLKEPSVRLREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKKKGPPLGAGKKPSSFRTPILNAKATFEDGPSPVLSMNSPYSLYSNNSPLPVLPRRISTHTTSGNGGNRRSSITNPVFNPRKPTLSTDSFSSSSNSSSRLRVNSINVKTPVGVSPKKELVSESVRHSATPTSPHNNIALINRYLLPNKSNDNVRGDSQTATINDDGGGGNGGDATIGMGLRKDPDDENENKYKIKVNNGEPRRRVSLLNIPISKLRNSNNTRAED
147	TSC11	856828	Target of rapamycin complex 2 subunit TSC11		AVO3	baker's yeast	NM_001178984.1	NP_011018.1	NC_001137.3	P40061	Cell membrane.	NULL			Essential component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway. TSC11 may exert its functions through two distinct mechanisms, one mediated by AVO1 and the other mediated by AVO2 and SLM1. {ECO:0000269|PubMed:15809876}.		8849441,9169868,9804843,11283351,11805826,11805837,12408816,12631735,14736892,15242642,15809876,16002396,16155567,16959779,17507646,18245329,18249174,18552287,19269370,19840948,20093466,20489023,21035341,21107429,21552543,22207764,22282571,22307609,22875988,22940862,23390603,24462291,24465216,25026036,25624345,26028537,26493364	28		NP_011018.1|MSIPHSAKQSSPLSSRRRSVTNTTPLLTPRHSRDNSSTQISSAKNITSSSPSTITNESSKRNKQNLVLSTSFISTKRLENSAPSPTSPLMARRTRSTMTKALLNLKAEINNQYQELARLRKKKDDIEHLRDSTISDIYSGSYSTNHLQKHSMRIRANTQLREIDNSIKRVEKHIFDLKQQFDKKRQRSLTTSSSIKADVGSIRNDDGQNNDSEELGDHDSLTDQVTLDDEYLTTPTSGTERNSQQNLNRNSTVNSRNNENHSTLSIPDLDGSNKVNLTGDTEKDLGDLENENQIFTSTTTEAATWLVSDYMQSFQEKNVNPDFIAQKANGLVTLLKEHSEIRKDLVLTSFMSSIQNLLLNGNKLIAASAYRVCRYLINSSIFIDELLELRLDAFIIISLAKDNSFQIEREQALKMVRRFIEYNNGVTQGIMQAIISCVEKPEDSLRHMALETLLELCFVAPEMVKECRGMRVIEGFLQDYTSFSLASVILDTILQLMATHKTRQHFLEDFNVSVLTTVFSDTNTKSNVNVEKMQNASTLISITLNSYNGFMLFSNNNFKPLKQLVSFFQIPICAQYLIDIFLDVLKIKPLPYKPRGRHSHSFKPIPSQYYKECMSVNQRLALIVLILENSEFVPHLLELLNEEDRDDHLVAKGRYLLTEYFNLRMNLVDKKYTSVSKPIYKENFTYVNETFQFKKIAYKMNRNRNTIGMSGIDYAQNIKSFSKNIKENTLLREVDDFRFRRMVYDSKVLQTKDFTRWNWNIINELLEGPLLNKKQLEELVKSTKFIRRLLVFYRPLRLRFSNVNKGAKLSQKYVQVGCQFFKTLTATPEGMKILMDDTKIIPQLASLMFRAMEGNISGNIFNKNKLREKIIFGYFKFIGILTQSKNGVHILTRWNFFTVIYKMFQFESKLGLEFLLLTIPELDLKYSSHCRVIIGKALVVANEKVRIEATKHIGDKLKELLSTKESDLKLKANKVKLQQFKMEMLTRQLYDLSPSVVAVADQALYECIVAGNGSEELGTSFRMFLNQMVFIRSPILFELLSRPYGFQLLNEINFVKEERDSWLSKKNIEYVHIVEEFLKKNESINAKSLTFQQKSRLPLHFYESLTKTEDGILLLSQTGDLVTFMNVIKKYVNGNNMATVENAKEILDLKAALWCVGFIGSTELGIGLLDNYSLVEDIIEVAYNASVTSVRFTAFYVLGLISMTREGCEILDEMGWNCCVSVQDEPIGIALPNRLDRFLSYNEHKWSAFGEYSDEMIVFNKSDGDLIEKCLPIEFDLDKLLKEKDTAENPLNEKIITNKYDNDITSQTITVSGENSSLFANEGLSSPYVTQYRNDDDSIESKVLHIVSQLGNHILSNHAVKEITEINNKYGPRLFENEKMFFKVFNMMSKYRFKPHVRKFLCGLFINNRALENVIRHDNKRDKRPANFTR
148	BIT61	853388	Target of rapamycin complex 2 subunit BIT61			baker's yeast	NM_001181491.1	NP_012477.1	NC_001142.9	P47041	Cell membrane.	NULL			Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway. {ECO:0000269|PubMed:14736892}.		8641269,8849441,10688190,11283351,14562095,14736892,15689497,16157669,18667435,18719252,19144819,19269370,19840948,20093466,21035341,21987634,22207764,22282571,25624345,26028537	28		NP_012477.1|MTAEDILLRERTSTTTQRPVNSEQYLNVQLATAPVKNFQTTSEISRQTLVDTSNDDVYSIKNLKGSRNPISPSVSNVGFQSIFHTVDHPRSKVSVASNHSLRSNDNASAATSKSGSSQIGESHSVDTVECSNNLSKKLSSDAISITQKSLHSTPSGRYMKGKASGFFNRRNRAHTTISSDPASFLTDSSTLHNSSHSFRNVIKNFFQNKSHRHIGQDAIEPAIPNSLSKFLHSSYGRHKSPSQFIHTNAGQLVDSGTSVYSLNVNPSGVNPNTIVEDPLSGTDPASPNPVSMLHDLLRNLPSLEANYKHFNSQELTTLTNNIWNIFCSNVAELFRTQRIWKLRAKIENFNEVLEFYCILKTDPRVTHSGMNRIISDLKEFLVSSLYNLENQIVFNYSNEDTINNALKRLGVIWRIFYQEVYYDLAAVLLPLDQSIREDGNSTVLKSGNESRTHINGNYSIGFLLLMCFRDSIVLPCYENFVNSNDGISKSFQLYIFNQEEESNVTETDKLTLLQ